{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T19:03:49Z","timestamp":1757617429519,"version":"3.44.0"},"reference-count":19,"publisher":"Japan Surgical Society","issue":"1","funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["24K11910"],"award-info":[{"award-number":["24K11910"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Surg Case Rep"],"published-print":{"date-parts":[[2025]]},"DOI":"10.70352\/scrj.cr.25-0247","type":"journal-article","created":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T22:09:24Z","timestamp":1757023764000},"page":"n\/a","source":"Crossref","is-referenced-by-count":0,"title":["Pancreatic Hemangioblastoma in a Patient with von Hippel-Lindau Disease: A Case Report"],"prefix":"10.70352","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6953-5634","authenticated-orcid":false,"given":"Naoto","family":"Nakamura","sequence":"first","affiliation":[{"name":"Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2815-6309","authenticated-orcid":false,"given":"Yosuke","family":"Kasai","sequence":"additional","affiliation":[{"name":"Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan"},{"name":"Department of Gastroenterological Surgery, Kyoto-Katsura Hospital, Kyoto, Kyoto, Japan"},{"name":"VHL Center, Kyoto University Hospital, Kyoto, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuyuki","family":"Nagai","sequence":"additional","affiliation":[{"name":"Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan"},{"name":"VHL Center, Kyoto University Hospital, Kyoto, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asahi","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kentaro","family":"Kadono","sequence":"additional","affiliation":[{"name":"Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norimitsu","family":"Uza","sequence":"additional","affiliation":[{"name":"VHL Center, Kyoto University Hospital, Kyoto, Kyoto, Japan"},{"name":"Division of Gastroenterology, Department of Internal Medicine, Graduate School of Medicine, Kobe University, Kobe, Hyogo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsuyoshi","family":"Ohno","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sho","family":"Koyasu","sequence":"additional","affiliation":[{"name":"VHL Center, Kyoto University Hospital, Kyoto, Kyoto, Japan"},{"name":"Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Nakamoto","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noritaka","family":"Sano","sequence":"additional","affiliation":[{"name":"VHL Center, Kyoto University Hospital, Kyoto, Kyoto, Japan"},{"name":"Department of Neurosurgery, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayako","family":"Takahashi","sequence":"additional","affiliation":[{"name":"VHL Center, Kyoto University Hospital, Kyoto, Kyoto, Japan"},{"name":"Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinya","family":"Otsuki","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kei","family":"Yamane","sequence":"additional","affiliation":[{"name":"Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takayuki","family":"Anazawa","sequence":"additional","affiliation":[{"name":"Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Ogiso","sequence":"additional","affiliation":[{"name":"Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2266-7722","authenticated-orcid":false,"given":"Yoichiro","family":"Uchida","sequence":"additional","affiliation":[{"name":"Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takamichi","family":"Ishii","sequence":"additional","affiliation":[{"name":"Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Etsuro","family":"Hatano","sequence":"additional","affiliation":[{"name":"Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"51119","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1) Lonser RR, Glenn GM, Walther M, et al. von Hippel-Lindau disease. Lancet 2003; 361: 2059\u201367.","DOI":"10.1016\/S0140-6736(03)13643-4"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Maher ER, Kaelin WG Jr. von Hippel-Lindau disease. Medicine (Baltimore) 1997; 76: 381\u201391.","DOI":"10.1097\/00005792-199711000-00001"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Maher ER, Neumann HP, Richard S. von Hippel-Lindau disease: a clinical and scientific review. Eur J Hum Genet 2011; 19: 617\u201323.","DOI":"10.1038\/ejhg.2010.175"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Maher ER, Yates JR, Harries R, et al. Clinical features and natural history of von Hippel-Lindau disease. QJM 1990; 77: 1151\u201363.","DOI":"10.1093\/qjmed\/77.2.1151"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Perez RL, Wu KJ, Nguyen BD. Extraneuraxial pancreatic hemangioblastoma in a patient with tuberous sclerosis. Jpn J Clin Oncol 2024; 54: 735\u20136.","DOI":"10.1093\/jjco\/hyae017"},{"key":"6","unstructured":"6) Shirakabe H, Nishizawa M, Higurashi K, et al. Hemangioblastoma cavernosum of the pancreas. Rinsho Hoshasen 1966; 11: 405\u20139."},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Latif F, Tory K, Gnarra J, et al. Identification of the von Hippel-Lindau disease tumor suppressor gene. Science 1993; 260: 1317\u201320.","DOI":"10.1126\/science.8493574"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Yamasaki I, Nishimori I, Ashida S, et al. Clinical characteristics of pancreatic neuroendocrine tumors in Japanese patients with von Hippel-Lindau disease. Pancreas 2006; 33: 382\u20135.","DOI":"10.1097\/01.mpa.0000240604.26312.e4"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Ito T, Masui T, Komoto I, et al. JNETS clinical practice guidelines for gastroenteropancreatic neuroendocrine neoplasms: diagnosis, treatment, and follow-up: a synopsis. J Gastroenterol 2021; 56: 1033\u201344.","DOI":"10.1007\/s00535-021-01827-7"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Blansfield JA, Choyke L, Morita SY, et al. Clinical, genetic and radiographic analysis of 108 patients with von Hippel-Lindau disease (VHL) manifested by pancreatic neuroendocrine tumors (PNETs). Surgery 2007; 142: 814\u20138.e2; discussion 818.e811\u20132.","DOI":"10.1016\/j.surg.2007.09.012"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Wanebo JE, Lonser RR, Glenn GM, et al. The natural history of hemangioblastomas of the central nervous system in patients with von Hippel-Lindau disease. J Neurosurg 2003; 98: 82\u201394.","DOI":"10.3171\/jns.2003.98.1.0082"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Boughey AM, Fletcher NA, Harding AE. Central nervous system haemangioblastoma: a clinical and genetic study of 52 cases. J Neurol Neurosurg Psychiatry 1990; 53: 644\u20138.","DOI":"10.1136\/jnnp.53.8.644"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Brodkey JA, Buchignani JA, O\u2019Brien TF. Hemangioblastoma of the radial nerve: case report. Neurosurgery. 1995; 36: 198\u2013201; discussion 200\u20131.","DOI":"10.1097\/00006123-199501000-00028"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Fanburg-Smith JC, Gyure KA, Michal M, et al. Retroperitoneal peripheral hemangioblastoma: a case report and review of the literature. Ann Diagn Pathol 2000; 4: 81\u20137.","DOI":"10.1016\/S1092-9134(00)90016-9"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Richard S, Campello C, Taillandier L, et al. Haemangioblastoma of the central nervous system in von Hippel-Lindau disease. French VHL Study Group. J Intern Med 1998; 243: 547\u201353.","DOI":"10.1046\/j.1365-2796.1998.00337.x"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Kanno H, Kuratsu J, Nishikawa R, et al. Clinical features of patients bearing central nervous system hemangioblastoma in von Hippel-Lindau disease. Acta Neurochir (Wien) 2013; 155: 1\u20137.","DOI":"10.1007\/s00701-012-1514-y"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Bisceglia M, Muscarella LA, Galliani CA, et al. Extraneuraxial hemangioblastoma: clinicopathologic features and review of the literature. Adv Anat Pathol 2018; 25: 197\u2013215.","DOI":"10.1097\/PAP.0000000000000176"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Nonaka D, Rodriguez J, Rosai J. Extraneural hemangioblastoma: a report of 5 cases. Am J Surg Pathol 2007; 31: 1545\u201351.","DOI":"10.1097\/PAS.0b013e3180457bfc"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Schaller T, Bode M, Berlis A, et al. Specific immunohistochemical pattern of carbonic anhydrase IX is helpful for the diagnosis of CNS hemangioblastoma. Pathol Res Pract 2015; 211: 513\u201320.","DOI":"10.1016\/j.prp.2015.03.003"}],"container-title":["Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/scrj\/11\/1\/11_cr.25-0247\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T04:18:17Z","timestamp":1757132297000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/scrj\/11\/1\/11_cr.25-0247\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.70352\/scrj.cr.25-0247","relation":{},"ISSN":["2198-7793"],"issn-type":[{"type":"electronic","value":"2198-7793"}],"subject":[],"published":{"date-parts":[[2025]]},"article-number":"cr.25-0247"}}