{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T07:26:23Z","timestamp":1774077983910,"version":"3.50.1"},"reference-count":27,"publisher":"Japan Surgical Society","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Surg Case Rep"],"published-print":{"date-parts":[[2026]]},"DOI":"10.70352\/scrj.cr.25-0779","type":"journal-article","created":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T22:11:39Z","timestamp":1773958299000},"page":"n\/a","source":"Crossref","is-referenced-by-count":0,"title":["Pancreaticobiliary Fistula Caused by Intraductal Papillary Mucinous Adenoma Requiring Pancreaticoduodenectomy"],"prefix":"10.70352","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-1241-2002","authenticated-orcid":false,"given":"Mina","family":"Nagao","sequence":"first","affiliation":[{"name":"Department of Gastroenterological Surgery, Kagawa University, Kita, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8476-3985","authenticated-orcid":false,"given":"Hironobu","family":"Suto","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Kagawa University, Kita, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Matsukawa","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Kagawa University, Kita, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junichi","family":"Fujiwara","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Kagawa University, Kita, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seiko","family":"Kagawa","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Kagawa University, Kita, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takuro","family":"Fuke","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Kagawa University, Kita, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshio","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Kagawa University, Kita, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arata","family":"Nishigaki","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Kagawa University, Kita, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8686-2810","authenticated-orcid":false,"given":"Yasuhisa","family":"Ando","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Kagawa University, Kita, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minoru","family":"Oshima","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Kagawa University, Kita, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9559-6182","authenticated-orcid":false,"given":"Keiichi","family":"Okano","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Kagawa University, Kita, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"51119","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1) Ohtsuka T, Fernandez-Del Castillo C, Furukawa T, et al. International evidence-based Kyoto guidelines for the management of intraductal papillary mucinous neoplasm of the pancreas. Pancreatology 2024; 24: 255\u201370.","DOI":"10.1016\/j.pan.2023.12.009"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Machado NO, Al Qadhi H, Al Wahibi K. Intraductal papillary mucinous neoplasm of pancreas. N Am J Med Sci 2015; 7: 160\u201375.","DOI":"10.4103\/1947-2714.157477"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Abe K, Kitago M, Masugi Y, et al. Indication for resection and possibility of observation for intraductal papillary mucinous neoplasm with high-risk stigmata. Pancreatology 2021; 21: 755\u201362.","DOI":"10.1016\/j.pan.2021.02.012"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Ecker BL, Dickinson SM, Saadat LV, et al. Segmental versus diffuse main duct intraductal papillary mucinous neoplasm: examination of main pancreatic duct morphology and implications for malignancy risk and extent of surgical resection. Ann Surg 2023; 278: 110\u20137.","DOI":"10.1097\/SLA.0000000000005672"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Shishido Y, Mitsuoka E, Ito R, et al. Fistula formation into other organs secondary to intraductal papillary mucinous neoplasm of the pancreas: a case report and literature review. Medicine (Baltimore) 2023; 102: e34288.","DOI":"10.1097\/MD.0000000000034288"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Itagaki Y, Sato S, Omori Y, et al. Pancreaticobiliary fistula associated with intraductal papillary mucinous neoplasm and the simultaneous ampullary carcinoma: a case report. Medicine (Baltimore) 2025; 104: e43563.","DOI":"10.1097\/MD.0000000000043563"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Okada K, Furuuchi T, Tamada T, et al. Pancreatobiliary fistula associated with an intraductal papillary-mucinous pancreatic neoplasm manifesting as obstructive jaundice: report of a case. Surg Today 2008; 38: 371\u20136.","DOI":"10.1007\/s00595-007-3630-5"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Mie T, Sasaki T, Takeda T, et al. A case of endoscopic ultrasound-guided hepaticogastrostomy for obstructive jaundice caused by intraductal papillary mucinous neoplasm-associated pancreatobiliary fistula. Clin J Gastroenterol 2021; 14: 893\u20138.","DOI":"10.1007\/s12328-021-01355-0"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Sung KF, Chu YY, Liu NJ, et al. Direct peroral cholangioscopy and pancreatoscopy for diagnosis of a pancreatobiliary fistula caused by an intraductal papillary mucinous neoplasm of the pancreas: a case report. Dig Endosc 2011; 23: 247\u201350.","DOI":"10.1111\/j.1443-1661.2011.01126.x"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Koizumi M, Kumagi T, Kuroda T, et al. Difficulty in management of intraductal papillary mucinous neoplasm-associated pancreatobiliary fistulas and the role of \u201cpig-nose\u201d appearance and intraductal ultrasonography in diagnosis. Endosc Int Open 2016; 4: E446\u201350.","DOI":"10.1055\/s-0042-102956"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Komo T, Oishi K, Kohashi T, et al. Pancreatobiliary fistula associated with intraductal papillary mucinous carcinoma accompanying obstructive jaundice: a case report. Int J Surg Case Rep 2018; 48: 126\u201330.","DOI":"10.1016\/j.ijscr.2018.05.019"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Jausset F, Delvaux M, Dumitriu D, et al. Benign intraductal papillary-mucinous neoplasm of the pancreas associated with spontaneous pancreaticogastric and pancreaticoduodenal fistulas. Digestion 2010; 82: 42\u20136.","DOI":"10.1159\/000265829"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Shimizu M, Kawaguchi A, Nagao S, et al. A case of intraductal papillary mucinous neoplasm of the pancreas rupturing both the stomach and duodenum. Gastrointest Endosc 2010; 71: 406\u201312.","DOI":"10.1016\/j.gie.2009.09.018"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Morotti A, Busso M, Rappa Verona P, et al. Gastropancreatic fistula in a patient with chronic pancreatitis and IPMN. BMJ Case Rep 2016; 2016.","DOI":"10.1136\/bcr-2016-215375"},{"key":"15","unstructured":"15) Kurihara K, Nagai H, Kasahara K, et al. Biliopancreatic fistula associated with intraductal papillary-mucinous pancreatic cancer: institutional experience and review of the literature. Hepatogastroenterology 2000; 47: 1164\u20137."},{"key":"16","unstructured":"16) Le Corguille M, L\u00e9vy P, Ponsot P, et al. Intraductal papillary mucinous tumor with pancreatobiliary and pancreatodigestive fistulae: a case report. Gastroenterol Clin Biol 2002; 26: 1172\u20134. (in French)"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Sano S, Nishimori I, Okamoto N, et al. Biliopancreatic fistula caused by an intraductal papillary-mucinous tumor of the pancreas confirmed by biochemical analysis of mucin. Int J Gastrointest Cancer 2003; 34: 101\u20136.","DOI":"10.1385\/IJGC:34:2-3:101"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Nagano H, Koneri K, Honda K, et al. Biliopancreatic fistula and abscess formation in the bursa omentalis associated with intraductal papillary mucinous cancer of the pancreas. Int J Clin Oncol 2009; 14: 460\u20134.","DOI":"10.1007\/s10147-008-0864-1"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Bong JJ, Wang J, Spalding DR. Pancreatobiliary and pancreatoduodenal fistulae in intraductal papillary mucinous neoplasm of the pancreas: report of a case. Surg Today 2011; 41: 281\u20134.","DOI":"10.1007\/s00595-009-4217-0"},{"key":"20","unstructured":"20) Goto N, Yoshioka M, Hayashi M, et al. Intraductal papillary-mucinous neoplasm of the pancreas penetrating to the stomach and the common bile duct. JOP 2012; 13: 61\u20135."},{"key":"21","doi-asserted-by":"crossref","unstructured":"21) Mihara K, Yamamoto Y, Sasaki K, et al. A case of pancreaticobiliary fistula associated with an intraductal papillary mucinous neoplasm of the pancreas. Jpn J Clin Oncol 2015; 45: 232.","DOI":"10.1093\/jjco\/hyu217"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Ren X, Zhu CL, Qin XF, et al. Co-occurrence of IPMN and malignant IPNB complicated by a pancreatobiliary fistula: a case report and review of the literature. World J Clin Cases 2019; 7: 102\u20138.","DOI":"10.12998\/wjcc.v7.i1.102"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) Khneizer G, Reddy KM, Hammami MB, et al. Formation of pancreatoduodenal fistula in intraductal papillary mucinous neoplasm of the pancreas decreased the frequency of recurrent pancreatitis. Gastroenterology Res 2019; 12: 43\u20137.","DOI":"10.14740\/gr1140"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24) Okamoto M, Kamitani Y, Iwamoto T, et al. Obstructive cholangitis by mucus from an intraductal papillary mucinous neoplasm with pancreatobiliary fistula treated by endoscopic septotomy and direct peroral cholangioscopy: a case report. Clin J Gastroenterol 2019; 12: 495\u20139.","DOI":"10.1007\/s12328-019-00973-z"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) Kumar M, Sonika U, Sachdeva S, et al. Mucin-filled CBD, difficult to manage cholangitis. BMJ Case Rep 2021; 14: e238363.","DOI":"10.1136\/bcr-2020-238363"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) Patel S, Al Salmi U, Al Shamousi K. Main-duct intraductal papillary mucinous neoplasm complicated by a pancreaticogastric fistula and a pancreaticocholedocal fistula. Cureus 2023; 15: e38502.","DOI":"10.7759\/cureus.38502"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27) Gon\u00e7alves A, Leal C, Cotrim I, et al. An elderly patient\u2019s pancreatobiliary puzzle: unraveling diagnosis and treatment challenges. Rev Esp Enferm Dig 2025; 117: 579\u201380.","DOI":"10.17235\/reed.2024.10125\/2023"}],"container-title":["Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/scrj\/12\/1\/12_cr.25-0779\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T04:11:35Z","timestamp":1774066295000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/scrj\/12\/1\/12_cr.25-0779\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.70352\/scrj.cr.25-0779","relation":{},"ISSN":["2198-7793"],"issn-type":[{"value":"2198-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"article-number":"cr.25-0779"}}