{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T05:20:01Z","timestamp":1783142401764,"version":"3.54.6"},"reference-count":20,"publisher":"Japan Surgical Society","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Surg Case Rep"],"published-print":{"date-parts":[[2026]]},"DOI":"10.70352\/scrj.cr.26-0123","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T22:20:34Z","timestamp":1782858034000},"page":"n\/a","source":"Crossref","is-referenced-by-count":0,"title":["Surgically Diagnosed Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia in Asymptomatic Patients"],"prefix":"10.70352","volume":"12","author":[{"given":"Chen","family":"Lu","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3054-6760","authenticated-orcid":false,"given":"Yosuke","family":"Matsuura","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgical Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruxue","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Pathology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abigail","family":"Fickel","sequence":"additional","affiliation":[{"name":"Mayo Clinic Alix School of Medicine, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangyao","family":"Ning","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenyu","family":"Sun","sequence":"additional","affiliation":[{"name":"Division of Public Health, Infectious Diseases, and Occupational Medicine, Mayo Clinic, Rochester, MN, USA"},{"name":"Mayo Clinic School of Graduate Medical Education, Mayo Clinic College of Medicine and Science, Rochester, MN, USA"},{"name":"School of Public Health, University of Minnesota-Twin Cities, Minneapolis, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"51119","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1) Samhouri BF, Halfdanarson TR, Koo CW, et al. DIPNECH: pragmatic approach, uncertainties, notable associations, and a proposal for an improved definition. Endocr Relat Cancer 2023; 30: e230051.","DOI":"10.1530\/ERC-23-0051"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Sun TY, Hwang G, Pancirer D, et al. Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia: clinical characteristics and progression to carcinoid tumour. Eur Respir J 2022; 59: 2101058.","DOI":"10.1183\/13993003.01058-2021"},{"key":"3","unstructured":"3) WHO Classification of Tumours Editorial Board. Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia. In: Thoracic tumours: WHO classification of tumours, 5th ed. Lyon: International Agency for Research on Cancer; 2021. p. 130."},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Hayes AR, Luong TV, Banks J, et al. Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH): prevalence, clinicopathological characteristics and survival outcome in a cohort of 311 patients with well-differentiated lung neuroendocrine tumours. J Neuroendocrinol 2022; 34: e13184.","DOI":"10.1111\/jne.13184"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Hurabielle C, Taill\u00e9 C, Pr\u00e9vot G, et al. De-labelling severe asthma diagnosis: the challenge of DIPNECH. ERJ Open Res 2022; 8: 00485\u20132021.","DOI":"10.1183\/23120541.00485-2021"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Gutierrez M, Alonso A, Penha D, et al. Radiological\u2013pathological correlation in diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH): imaging and histopathology. Clin Radiol 2024; 79: 133\u201341.","DOI":"10.1016\/j.crad.2023.10.013"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Kligerman SJ, Henry T, Lin CT, et al. Mosaic attenuation: etiology, methods of differentiation, and pitfalls. Radiographics 2015; 35: 1360\u201380.","DOI":"10.1148\/rg.2015140308"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Samhouri BF, Koo CW, Yi ES, et al. Is the combination of bilateral pulmonary nodules and mosaic attenuation on chest CT specific for DIPNECH? Orphanet J Rare Dis 2021; 16: 490.","DOI":"10.1186\/s13023-021-02103-w"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Inomata S, Matsumura Y, Kobayashi Y, et al. Lung adenocarcinoma coexisting with diffuse idiopathic pulmonary neuroendocrine cell hyperplasia manifesting as multiple pulmonary nodules: a case report. Thorac Cancer 2022; 13: 3076\u20139.","DOI":"10.1111\/1759-7714.14662"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Worrell JC, O\u2019Brien H, Quinn S, et al. Neuroendocrine hyperplasia of infancy and diffuse idiopathic neuroendocrine cell hyperplasia: two faces of pulmonary neuroendocrine cell pathology. Clin Chest Med 2025; 46: 727\u201338.","DOI":"10.1016\/j.ccm.2025.07.011"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Samhouri BF, Azadeh N, Halfdanarson TR, et al. Constrictive bronchiolitis in diffuse idiopathic pulmonary neuroendocrine cell hyperplasia. ERJ Open Res 2020; 6: 00527\u20132020.","DOI":"10.1183\/23120541.00527-2020"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Little BP, Junn JC, Zheng KS, et al. Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia: imaging and clinical features of a frequently delayed diagnosis. AJR Am J Roentgenol 2020; 215: 1312\u201320.","DOI":"10.2214\/AJR.19.22628"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Mengoli MC, Rossi G, Cavazza A, et al. Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (dipnech) syndrome and carcinoid tumors with\/without nech: a clinicopathologic, radiologic, and immunomolecular comparison study. Am J Surg Pathol 2018; 42: 646\u201355.","DOI":"10.1097\/PAS.0000000000001033"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Sazonova O, Manem V, B\u00e9land C, et al. Development and validation of diffuse idiopathic pulmonary neuroendocrine hyperplasia diagnostic criteria. JTO Clin Res Rep 2020; 1: 100078.","DOI":"10.1016\/j.jtocrr.2020.100078"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Wen M, Zheng Q, Ji X, et al. Precise diagnosis and prognosis assessment of malignant lung nodules: a narrative review. J Thorac Dis 2024; 16: 7999\u20138013.","DOI":"10.21037\/jtd-24-1058"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Herr\u00e1n de la Gala D, Calapaqu\u00ed Ter\u00e1n AK, Pe\u00f1a G\u00f3mez ME. Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia: a rare and under-diagnosed condition. Pulmonology 2022; 28: 324\u20135.","DOI":"10.1016\/j.pulmoe.2021.12.011"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Al-Toubah T, Grozinsky-Glasberg S, Strosberg J. An update on the management of diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH). Curr Treat Options Oncol 2021; 22: 28.","DOI":"10.1007\/s11864-021-00828-1"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Ramirez RA, Cass AS, Das S, et al. A multidisciplinary approach to the work up and management of pulmonary carcinoid tumors and DIPNECH: a narrative review. Transl Lung Cancer Res 2022; 11: 2567\u201387.","DOI":"10.21037\/tlcr-22-415"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Bennett KH, Khor BY, Hughes S, et al. A multi-lesional analysis of diffuse idiopathic pulmonary neuroendocrine cell hyperplasia: a single-centre analysis. Clin Radiol 2024; 79: 413\u20139.","DOI":"10.1016\/j.crad.2024.01.036"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Chung C, Bommart S, Marchand-Adam S, et al. Long-term imaging follow-up in DIPNECH: multicenter experience. J Clin Med 2021; 10: 2950.","DOI":"10.3390\/jcm10132950"}],"container-title":["Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/scrj\/12\/1\/12_cr.26-0123\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T05:10:36Z","timestamp":1783141836000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/scrj\/12\/1\/12_cr.26-0123\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.70352\/scrj.cr.26-0123","relation":{},"ISSN":["2198-7793"],"issn-type":[{"value":"2198-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"article-number":"cr.26-0123"}}