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This review examines the interplay between obesity, microbial dysbiosis, and two archetypal inflammatory skin disorders\u2014hidradenitis suppurativa (HS) and psoriasis. We highlight how obesity-induced changes in immune signaling, gut permeability, and microbiota composition\u2014both in the gut and the skin\u2014contribute to cutaneous inflammation. Special emphasis is placed on shared pathways such as the Th17\/IL-23 and IL-22 signaling axes, adipokine imbalance, and microbial metabolites like short-chain fatty acids and lipopolysaccharides. The review critically evaluates the current literature, distinguishing preclinical insights from clinical evidence, and underscores the potential of microbiota-targeted therapies and metabolic interventions as adjunctive treatment strategies. 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