{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T17:44:56Z","timestamp":1782841496695,"version":"3.54.5"},"reference-count":0,"publisher":"ECMS","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,23]]},"abstract":"<jats:p>Laryngeal oncosurgery often results in severely impaired speech with unstable voicing and spectral aperiodicity. This paper compares two subdifferential-optimization paradigms within the same clinical pathological speech synthesis backbone to isolate how nonsmooth optimization geometry shapes rehabilitation-relevant outcomes: (i) the Ioffe Subdifferential Optimization Framework (ISOF) for robust long\u2011form pathological speech synthesis and (ii) the Mordukhovich Subdifferential Optimization (MSO) paradigm for multi\u2011criteria voice cloning into a single clinical framework. ISOF combines approximate subgradients via minimum\u2011norm convex combinations and proximal anchoring, MSO balances naturalness, similarity, efficiency, and pathology preservation. ISOF improved AVE, PVF, PVS, HNR, CPP and markedly increased ASVI; no degradation from beginning to end in running speech. MSO achieved high MOS\/SMOS and strong objective scores (lower MCD, VDE, GPE, FFE; higher STOI, SII). ISOF+MSO approaches yielded stable, intelligible synthesized speech suitable for rehabilitation, preserving medically plausible signatures.<\/jats:p>","DOI":"10.7148\/2026-0547","type":"proceedings-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T16:55:14Z","timestamp":1782838514000},"page":"547-553","source":"Crossref","is-referenced-by-count":0,"title":["Pathological speech synthesis modelling after laryngeal oncosurgery: comparing isof and mso approaches"],"prefix":"10.7148","author":[{"given":"Rytis","family":"Maskeliunas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Blazauskas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robertas","family":"Damasevicius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kipras","family":"Pribuisis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virgilijus","family":"Uloza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4144","published-online":{"date-parts":[[2026,6,23]]},"event":{"name":"40th ECMS International Conference on Modelling and Simulation"},"container-title":["ECMS 2026 Proceedings edited by Filippo Sanfilippo, Florenc Demrozi, Fabio Sgarbossa, Mohammad Poursina"],"original-title":[],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T16:55:20Z","timestamp":1782838520000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scs-europe.net\/dlib\/2026\/ecms2026acceptedpapers\/0547_simo_ecms2026_0070.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,23]]},"references-count":0,"URL":"https:\/\/doi.org\/10.7148\/2026-0547","relation":{},"subject":[],"published":{"date-parts":[[2026,6,23]]}}}