{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T03:57:32Z","timestamp":1792814252067,"version":"4.5.0"},"reference-count":0,"publisher":"Ivyspring International Publisher","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Theranostics"],"published-print":{"date-parts":[[2026,1,1]]},"DOI":"10.7150\/thno.122246","type":"journal-article","created":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T09:19:25Z","timestamp":1766049565000},"page":"2721-2747","source":"Crossref","is-referenced-by-count":1,"title":["Neuron-specific WDR5 epigenetically upregulates ARID5B to impair GABAergic synaptic transmission and promotes epileptogenesis"],"prefix":"10.7150","volume":"16","author":[{"given":"Juan","family":"Gu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping-Yang","family":"Ke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin-Yu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Lan","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen-Zhong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Xiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4137","container-title":["Theranostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.thno.org\/v16p2721.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T09:19:51Z","timestamp":1766049591000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.thno.org\/v16p2721.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,1]]},"references-count":0,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.7150\/thno.122246","relation":{},"ISSN":["1838-7640"],"issn-type":[{"value":"1838-7640","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1,1]]}}}