{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:13:27Z","timestamp":1761743607408},"reference-count":7,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>\n          Introduction:\u2003The cocaine is obtained from the leaves of the coca (Erythroxylon coca). It can be used in many ways, but the most common is the drug inhalation. The Cocaine also causes vasoconstriction at nasal mucous membrane and its chronic use can cause necrosis and nasal septum perforation. Pyoderma gangrenosum is an uncommon idiopathic disease characterized by ulcerations, usually observed on the legs. Its diagnosis is most common an exclusion of others diseases. So far, there is no specific treatment based on evidence by randomized controlled trials.<\/jats:p><jats:p>\n          Objective:\u2003Describe the rare association between Pyoderma gangrenosum and cocaine.<\/jats:p><jats:p>\n          Case Report:\u2003E. A., 27-year-old woman with destruction of nasal septum and palate who has been using a big amount of cocaine, been necessary note the difference from which disease cause de damage.<\/jats:p><jats:p>\n          Final Comments:\u2003Also there are only three cases of Pyoderma gangrenosum complicated with nasal septum perforation in cocaine users.<\/jats:p>","DOI":"10.7162\/s1809-97772012000200018","type":"journal-article","created":{"date-parts":[[2012,5,7]],"date-time":"2012-05-07T08:32:18Z","timestamp":1336379538000},"page":"278-281","source":"Crossref","is-referenced-by-count":6,"title":["Nasal septum perforation in patient with pyoderma gangrenosum"],"prefix":"10.1055","volume":"16","author":[{"given":"Felippe","family":"Felix","sequence":"first","affiliation":[{"name":"Master for the UFRJ. Doctor of the Department of Otolaryngology of the State Serving Hospital, Health department, Rio de Janeiro."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vania","family":"Paes","sequence":"first","affiliation":[{"name":"Medical Teacher of the Hospital of the State Server."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia Alves","family":"de Azevedo","sequence":"first","affiliation":[{"name":"Resident Doctor (a) of Otolaryngology of the Hospital of the State Server, Health department, Rio de Janeiro."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliza Raquel Negr\u00e3o","family":"Grangeiro","sequence":"first","affiliation":[{"name":"Resident Doctor of Dermatology of the Hospital of the State Server, Health department, Rio de Janeiro."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonatah Lucas N.","family":"Riccio","sequence":"first","affiliation":[{"name":"Resident Doctor (a) of Otolaryngology of the Hospital of the State Server, Health department, Rio de Janeiro."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen Cruz","family":"Rito","sequence":"first","affiliation":[{"name":"Resident Doctor (a) of Otolaryngology of the Hospital of the State Server, Health department, Rio de Janeiro."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camilla Bezerra da Cruz","family":"Maia","sequence":"additional","affiliation":[{"name":"Resident Doctor of Otolaryngology."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2013,12,5]]},"reference":[{"key":"ref1","first-page":"655","article-title":"Pyoderma (echthyma) gangrenosum: clinical and experimental observations in five cases occurring in adults","volume":"22","year":"1930","journal-title":"Arch Dermatol"},{"issue":"1","key":"ref2","first-page":"37","article-title":"Pyoderma gangrenosum: a comparison of typical and atypical forms with an emphasis on time to remission. Case review of 86 patients from 2 institutions","volume":"79","year":"2000"},{"key":"ref3","volume-title":"Pyoderma Gangrenosum: an update","year":"2007"},{"issue":"1","key":"ref4","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1590\/S0365-05962005000100011","article-title":"Pioderma Gangrenoso e Artrite Reumat\u00f3ide - Relato de Caso","volume":"80","year":"2005","journal-title":"An Bras Dermatol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1111\/j.1610-0387.2007.0328.x","article-title":"Pyoderma gangrenosum: clinical presentation and outcome in 18 cases and review of the literature","volume":"5","year":"2007","journal-title":"J Dtsch Dermatol Ges"},{"issue":"2","key":"ref6","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.jaad.2004.10.006","article-title":"Treatment recommendations for Pyoderma gangrenosum: An evidence based review of the literature based on more than 350 patients","volume":"53","year":"2005","journal-title":"J Am Acad Dermatol"},{"key":"ref7","volume-title":"Neutrophilic Dermatoses","year":"2008"}],"container-title":["International Archives of Otorhinolaryngology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.7162\/S1809-97772012000200018.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T05:38:04Z","timestamp":1705556284000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.7162\/S1809-97772012000200018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4]]},"references-count":7,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2013,12,5]]},"published-print":{"date-parts":[[2012,4]]}},"URL":"https:\/\/doi.org\/10.7162\/s1809-97772012000200018","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1809-9777","1809-4864"],"issn-type":[{"value":"1809-9777","type":"print"},{"value":"1809-4864","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4]]}}}