{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T22:22:06Z","timestamp":1763072526986,"version":"3.45.0"},"reference-count":39,"publisher":"International Society of Global Health","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Glob Health"],"DOI":"10.7189\/jogh.15.04129","type":"journal-article","created":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T22:19:10Z","timestamp":1763072350000},"source":"Crossref","is-referenced-by-count":0,"title":["COVID-19 vaccination and miscarriage risk: RNA-seq and bioinformatics analysis at the maternal-foetal interface"],"prefix":"10.7189","volume":"15","author":[{"given":"Yiyuan","family":"Qu","sequence":"first","affiliation":[{"name":"Department of Obstetrics-Gynecology, Center for Reproduction, the Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Yiwu, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chengcheng","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics-Gynecology, Center for Reproduction, the Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Yiwu, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Obstetrics-Gynecology, Center for Reproduction, the Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Yiwu, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianqiu","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics-Gynecology, Center for Reproduction, the Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Yiwu, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics-Gynecology, Center for Reproduction, the Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Yiwu, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linping","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Obstetrics-Gynecology, Center for Reproduction, the Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Yiwu, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xujia","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics-Gynecology, Center for Reproduction, the Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Yiwu, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bingbing","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics-Gynecology, Center for Reproduction, the Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Yiwu, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics-Gynecology, Center for Reproduction, the Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Yiwu, Zhejiang, China"},{"name":"Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiuying","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics-Gynecology, Center for Reproduction, the Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Yiwu, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4223","published-online":{"date-parts":[[2025,11,14]]},"reference":[{"key":"key-10.7189\/jogh.15.04129-202511132028-R1","doi-asserted-by":"publisher","first-page":"6213","DOI":"10.1021\/acsnano.0c02250","article-title":"Reusable and Recyclable Graphene Masks with Outstanding Superhydrophobic and Photothermal Performances.","volume":"14","author":"Zhong","year":"2020","journal-title":"ACS Nano"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R2","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1016\/j.chom.2017.04.007","article-title":"Microbial Vertical Transmission during Human Pregnancy.","volume":"21","author":"Arora","year":"2017","journal-title":"Cell Host Microbe"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R3","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1016\/j.ajog.2020.02.017","article-title":"Coronavirus Disease 2019 (COVID-19) and pregnancy: what obstetricians need to know.","volume":"222","author":"Rasmussen","year":"2020","journal-title":"Am J Obstet Gynecol"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R4","doi-asserted-by":"publisher","first-page":"e2313","DOI":"10.1002\/rmv.2313","article-title":"Covid-19 vaccines and variants of concern: A review.","volume":"32","author":"Hadj Hassine","year":"2022","journal-title":"Rev Med Virol"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R5","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1038\/s41577-021-00526-x","article-title":"COVID-19 vaccines: modes of immune activation and future challenges.","volume":"21","author":"Teijaro","year":"2021","journal-title":"Nat Rev Immunol"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R6","unstructured":"Johns Hopkings Coronavirus Resource Center. COVID-19 United States Cases by County. 2023. Available: https:\/\/coronavirus.jhu.edu\/us-map\/. Accessed: 18 December 2023."},{"key":"key-10.7189\/jogh.15.04129-202511132028-R7","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.ophtha.2022.08.027","article-title":"Vaccine-Associated Uveitis after COVID-19 Vaccination: Vaccine Adverse Event Reporting System Database Analysis.","volume":"130","author":"Singh","year":"2023","journal-title":"Ophthalmology"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R8","doi-asserted-by":"publisher","first-page":"1533","DOI":"10.1056\/NEJMc2113891","article-title":"Receipt of mRNA Covid-19 Vaccines and Risk of Spontaneous Abortion.","volume":"385","author":"Zauche","year":"2021","journal-title":"N Engl J Med"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R9","doi-asserted-by":"publisher","first-page":"758281","DOI":"10.3389\/fimmu.2021.758281","article-title":"Crosstalk Between Trophoblast and Macrophage at the Maternal-Fetal Interface: Current Status and Future Perspectives.","volume":"12","author":"Ding","year":"2021","journal-title":"Front Immunol"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R10","doi-asserted-by":"publisher","first-page":"2317","DOI":"10.3389\/fimmu.2019.02317","article-title":"Dynamic Function and Composition Changes of Immune Cells During Normal and Pathological Pregnancy at the Maternal-Fetal Interface.","volume":"10","author":"Yang","year":"2019","journal-title":"Front Immunol"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R11","doi-asserted-by":"publisher","first-page":"713","DOI":"10.21037\/atm-22-2287","article-title":"Narrative review of the relationship between the maternal-fetal interface immune tolerance and the onset of preeclampsia.","volume":"10","author":"Luo","year":"2022","journal-title":"Ann Transl Med"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R12","doi-asserted-by":"publisher","first-page":"e2434","DOI":"10.1002\/rmv.2434","article-title":"Effects of COVID-19 vaccination during pregnancy on SARS-CoV-2 infection and maternal and neonatal outcomes: A systematic review and meta-analysis.","volume":"33","author":"Rahmati","year":"2023","journal-title":"Rev Med Virol"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R13","unstructured":"National Institutes of Health. Gene Expression Omnibus. 2024. Available: https:\/\/www.ncbi.nlm.nih.gov\/geo\/. Accessed: 15 May 2025."},{"key":"key-10.7189\/jogh.15.04129-202511132028-R14","unstructured":"GeneCards. GeneCards: The Human Gene Database. 2025. Available: https:\/\/www.genecards.org\/. Accessed: 15 May 2025."},{"key":"key-10.7189\/jogh.15.04129-202511132028-R15","unstructured":"National Library of Medicine. PubMed. 2025. Available: https:\/\/pubmed.ncbi.nlm.nih.gov. Accessed: 15 May 2025."},{"key":"key-10.7189\/jogh.15.04129-202511132028-R16","unstructured":"Gene SEA. Molecular Signatures Data. 2011. Available: https:\/\/www.gsea-msigdb.org\/gsea\/msigdb. Accessed: 15 May 2025."},{"key":"key-10.7189\/jogh.15.04129-202511132028-R17","doi-asserted-by":"publisher","first-page":"P3","DOI":"10.1186\/gb-2003-4-5-p3","article-title":"DAVID: Database for Annotation, Visualization, and Integrated Discovery.","volume":"4","author":"Dennis","year":"2003","journal-title":"Genome Biol"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R18","doi-asserted-by":"crossref","unstructured":"STRING. STRING: functional protein association networks. 2017. Available: https:\/\/cn.string-db.org. Accessed: 18 December 2023.","DOI":"10.1177\/00031313231222150"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R19","unstructured":"GeneMANIA. Genemania.org. 2016. Available: https:\/\/genemania.org. Accessed: 18 December 2023."},{"key":"key-10.7189\/jogh.15.04129-202511132028-R20","unstructured":"Cytoscape. Cytoscape: a software environment for integrated models of biomolecular interaction networks. 2018. Available: https:\/\/cytoscape.org. Accessed: 18 December 2023."},{"key":"key-10.7189\/jogh.15.04129-202511132028-R21","doi-asserted-by":"publisher","first-page":"D607","DOI":"10.1093\/nar\/gky1131","article-title":"STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets.","volume":"47","author":"Szklarczyk","year":"2019","journal-title":"Nucleic Acids Res"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R22","unstructured":"Teichmann Lab. Data. 2013. Available: https:\/\/data.teichlab.org. Accessed: 18 December 2023."},{"key":"key-10.7189\/jogh.15.04129-202511132028-R23","doi-asserted-by":"publisher","first-page":"2277","DOI":"10.1007\/s00384-022-04265-w","article-title":"Risk of adverse outcomes in inflammatory bowel disease patients infected with SARS-CoV-2: a systematic review and meta-analysis.","volume":"37","author":"Chen","year":"2022","journal-title":"Int J Colorectal Dis"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R24","doi-asserted-by":"publisher","first-page":"166198","DOI":"10.1016\/j.bbadis.2021.166198","article-title":"Pregnancy and viral infections: Mechanisms of fetal damage, diagnosis and prevention of neonatal adverse outcomes from cytomegalovirus to SARS-CoV-2 and Zika virus.","volume":"1867","author":"Auriti","year":"2021","journal-title":"Biochim Biophys Acta Mol Basis Dis"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R25","doi-asserted-by":"publisher","first-page":"1469","DOI":"10.1001\/jama.2022.3271","article-title":"Association of SARS-CoV-2 Vaccination During Pregnancy With Pregnancy Outcomes.","volume":"327","author":"Magnus","year":"2022","journal-title":"JAMA"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R26","doi-asserted-by":"publisher","first-page":"2414","DOI":"10.1038\/s41467-022-30052-w","article-title":"Systematic review and meta-analysis of the effectiveness and perinatal outcomes of COVID-19 vaccination in pregnancy.","volume":"13","author":"Prasad","year":"2022","journal-title":"Nat Commun"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R27","doi-asserted-by":"publisher","first-page":"6588","DOI":"10.1002\/jmv.27214","article-title":"Safety of COVID-19 vaccines.","volume":"93","author":"Al Khames Aga","year":"2021","journal-title":"J Med Virol"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R28","doi-asserted-by":"publisher","first-page":"e13625","DOI":"10.1111\/aji.13625","article-title":"The impact of maternal SARS-CoV-2 vaccination and first trimester infection on feto-maternal immune responses.","volume":"88","author":"Juttukonda","year":"2022","journal-title":"Am J Reprod Immunol"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R29","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1093\/ajcp\/aqaa089","article-title":"Placental Pathology in COVID-19.","volume":"154","author":"Shanes","year":"2020","journal-title":"Am J Clin Pathol"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R30","doi-asserted-by":"publisher","first-page":"783","DOI":"10.3389\/fcell.2020.00783","article-title":"Single-Cell RNA-seq Identifies Cell Subsets in Human Placenta That Highly Expresses Factors Driving Pathogenesis of SARS-CoV-2.","volume":"8","author":"Ashary","year":"2020","journal-title":"Front Cell Dev Biol"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R31","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1016\/j.placenta.2015.03.004","article-title":"NOD1 and NOD2 control the invasiveness of trophoblast cells via the MAPK\/p38 signaling pathway in human first-trimester pregnancy.","volume":"36","author":"Wang","year":"2015","journal-title":"Placenta"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R32","doi-asserted-by":"publisher","first-page":"3209","DOI":"10.1080\/14767058.2020.1817369","article-title":"The expression of intracellular cytokines of decidual natural killer cells in unexplained recurrent pregnancy loss.","volume":"35","author":"Liu","year":"2022","journal-title":"J Matern Fetal Neonatal Med"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R33","doi-asserted-by":"publisher","first-page":"157","DOI":"10.3109\/09513590.2013.871514","article-title":"Higher levels of circulating CXCL-9 and CXCL-11 in euthyroid women with autoimmune thyroiditis and recurrent spontaneous abortions.","volume":"30","author":"Aktas","year":"2014","journal-title":"Gynecol Endocrinol"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R34","doi-asserted-by":"publisher","first-page":"ftx007","DOI":"10.1093\/femspd\/ftx007","article-title":"Involvement of matrix metalloproteinases and their inhibitors in endometrial extracellular matrix turnover in Chlamydia trachomatis-infected recurrent spontaneous aborters.","volume":"75","author":"Singh","year":"2017","journal-title":"Pathog Dis"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R35","doi-asserted-by":"publisher","first-page":"4522","DOI":"10.1039\/D2BM01997C","article-title":"Anti-aging biomaterial sturgeon chondroitin sulfate upregulating anti-oxidant and SIRT-1\/c-fos gene expression to reprogram stem cell senescence and prolong longevity.","volume":"11","author":"Singh","year":"2023","journal-title":"Biomater Sci"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R36","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1136\/jcp-2023-208931","article-title":"New kids on the block: FOS and FOSB gene.","volume":"76","author":"Cordier","year":"2023","journal-title":"J Clin Pathol"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R37","doi-asserted-by":"publisher","first-page":"1191","DOI":"10.1038\/nature07830","article-title":"The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex.","volume":"458","author":"Park","year":"2009","journal-title":"Nature"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R38","doi-asserted-by":"publisher","first-page":"1608","DOI":"10.3390\/ijms25031608","article-title":"Global Transcriptomic Analysis of Placentas from Women with Gestational SARS-CoV-2 Infection during the Third Trimester of Pregnancy.","volume":"25","author":"Tang","year":"2024","journal-title":"Int J Mol Sci"},{"key":"key-10.7189\/jogh.15.04129-202511132028-R39","doi-asserted-by":"publisher","first-page":"9203","DOI":"10.2147\/IJGM.S339194","article-title":"Altered NCF2, NOX2 mRNA Expression Levels in Peripheral Blood Mononuclear Cells of Pulmonary Tuberculosis Patients.","volume":"14","author":"Li","year":"2021","journal-title":"Int J Gen Med"}],"container-title":["Journal of Global Health"],"original-title":[],"link":[{"URL":"https:\/\/jogh.org\/2025\/jogh-15-04129","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T22:19:11Z","timestamp":1763072351000},"score":1,"resource":{"primary":{"URL":"https:\/\/jogh.org\/2025\/jogh-15-04129"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,14]]},"references-count":39,"URL":"https:\/\/doi.org\/10.7189\/jogh.15.04129","relation":{},"ISSN":["2047-2978","2047-2986"],"issn-type":[{"type":"print","value":"2047-2978"},{"type":"electronic","value":"2047-2986"}],"subject":[],"published":{"date-parts":[[2025,11,14]]},"article-number":"04129"}}