{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T07:57:31Z","timestamp":1785484651740,"version":"3.56.0"},"reference-count":46,"publisher":"International Society of Global Health","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Glob Health"],"DOI":"10.7189\/jogh.16.04258","type":"journal-article","created":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T07:00:14Z","timestamp":1785481214000},"source":"Crossref","is-referenced-by-count":0,"title":["Aggressive end-of-life care among over half a million patients with cancer in Shandong, China, 2017\u20132022"],"prefix":"10.7189","volume":"16","author":[{"given":"Ying","family":"Meng","sequence":"first","affiliation":[{"name":"School of Public Health, Peking University, Beijing, China"},{"name":"China Center for Health Development Studies, Peking University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Public Health, Shandong University, Jinan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"He","sequence":"additional","affiliation":[{"name":"Chinese Preventive Medicine Association, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaoyun","family":"Zhang","sequence":"additional","affiliation":[{"name":"China Center for Health Development Studies, Peking University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinxin","family":"Xia","sequence":"additional","affiliation":[{"name":"China Center for Health Development Studies, Peking University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaokang","family":"Ji","sequence":"additional","affiliation":[{"name":"School of Public Health, Shandong University, Jinan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingbo","family":"Zhao","sequence":"additional","affiliation":[{"name":"School of Public Health, Shandong University, Jinan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongchao","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Public Health, Shandong University, Jinan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifu","family":"Zhao","sequence":"additional","affiliation":[{"name":"School of Public Health, Shandong University, Jinan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ding","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Public Health, Shandong University, Jinan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Ke","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Molecular Oncology, Beijing Key Laboratory of Carcinogenesis and Translational Research, Department of Genetics, Peking University Cancer Hospital and Institute, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuzhong","family":"Xue","sequence":"additional","affiliation":[{"name":"School of Public Health, Shandong University, Jinan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Xu","sequence":"additional","affiliation":[{"name":"China Center for Health Development Studies, Peking University, Beijing, China"},{"name":"World Health Organization Collaborating Centre for Universal Health Coverage, Beijing, China"},{"name":"National Health Commission Key Laboratory of Health System Reform and Governance Research, Peking University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4223","published-online":{"date-parts":[[2026,7,31]]},"reference":[{"key":"key-10.7189\/jogh.16.04258-202607300859-R1","doi-asserted-by":"publisher","first-page":"e419","DOI":"10.1016\/j.jpainsymman.2021.12.015","article-title":"Cross country comparison of expert assessments of the quality of death and dying 2021.","volume":"63","author":"Finkelstein","year":"2022","journal-title":"J Pain Symptom Manage"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R2","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.jncc.2024.01.006","article-title":"Cancer incidence and mortality in China, 2022.","volume":"4","author":"Han","year":"2024","journal-title":"J Natl Cancer Cent"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R3","unstructured":"National Health Commission of the People\u2019s Republic of China. 2023 China Health Statistics Yearbook. Beijing, China: Peking Union Medical College Press; 2024. Chinese."},{"key":"key-10.7189\/jogh.16.04258-202607300859-R4","doi-asserted-by":"publisher","first-page":"20","DOI":"10.7150\/jca.78491","article-title":"Estimation of the three phases by direct cost of care for non-surviving patients with cancer: a national population-based patient-level study.","volume":"15","author":"Youk","year":"2024","journal-title":"J Cancer"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R5","doi-asserted-by":"publisher","first-page":"4907","DOI":"10.1200\/JCO.2004.06.050","article-title":"Perspectives, preferences, care practices, and outcomes among older and middle-aged patients with late-stage cancer.","volume":"22","author":"Rose","year":"2004","journal-title":"J Clin Oncol"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R6","doi-asserted-by":"publisher","first-page":"4387","DOI":"10.1200\/JCO.2012.43.6055","article-title":"Associations between end-of-life discussion characteristics and care received near death: a prospective cohort study.","volume":"30","author":"Mack","year":"2012","journal-title":"J Clin Oncol"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R7","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1001\/jama.2015.18604","article-title":"Family perspectives on aggressive cancer care near the end of life.","volume":"315","author":"Wright","year":"2016","journal-title":"JAMA"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R8","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.1200\/JCO.2010.31.9897","article-title":"Trends in the aggressiveness of end-of-life cancer care in the universal health care system of Ontario, Canada.","volume":"29","author":"Ho","year":"2011","journal-title":"J Clin Oncol"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R9","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1001\/jama.2015.18603","article-title":"Comparison of site of death, health care utilisation, and hospital expenditures for patients dying with cancer in 7 developed countries.","volume":"315","author":"Bekelman","year":"2016","journal-title":"JAMA"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R10","doi-asserted-by":"publisher","first-page":"e2440977","DOI":"10.1001\/jamanetworkopen.2024.40977","article-title":"Timing of palliative care, end-of-life quality indicators, and health resource utilisation.","volume":"7","author":"Mah","year":"2024","journal-title":"JAMA Netw Open"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R11","doi-asserted-by":"publisher","first-page":"e017624","DOI":"10.1136\/bmjgh-2024-017624","article-title":"Confronting global inequities in palliative care.","volume":"10","author":"Peeler","year":"2025","journal-title":"BMJ Glob Health"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R12","unstructured":"Economist Intelligence Unit. 2015 Quality of Death Index. 2015. Available: https:\/\/impact.economist.com\/health\/2015-quality-death-index. Accessed: 9 December 2025."},{"key":"key-10.7189\/jogh.16.04258-202607300859-R13","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1200\/JCO.2004.08.136","article-title":"Trends in the aggressiveness of cancer care near the end of life.","volume":"22","author":"Earle","year":"2004","journal-title":"J Clin Oncol"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R14","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1186\/s12904-019-0426-5","article-title":"Catastrophic health expenditure of cancer patients at the end-of-life: a retrospective observational study in China.","volume":"18","author":"Leng","year":"2019","journal-title":"BMC Palliat Care"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R15","doi-asserted-by":"publisher","first-page":"e026309","DOI":"10.1136\/bmjopen-2018-026309","article-title":"End-of-life cost and its determinants for cancer patients in urban China: a population-based retrospective study.","volume":"9","author":"Li","year":"2019","journal-title":"BMJ Open"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R16","first-page":"2315","article-title":"[Current situation and countermeasures for the construction of hospice care service system in China from the perspective of healthy ageing].","volume":"25","author":"Luo","year":"2022","journal-title":"Chin Gen Pract"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R17","unstructured":"National Healthcare Security Administration. \u201cAir medical transport\u201d, \u201chospice care\u201d, \u201csingle-room inpatient bed fee\u201d and 36 other items included in the Guideline for Establishing Comprehensive Consultation Medical Service Price Items, trial version. 2024. Available: https:\/\/www.nhsa.gov.cn\/art\/2024\/11\/12\/art_14_14650.html. Accessed: 12 August 2025. Chinese."},{"key":"key-10.7189\/jogh.16.04258-202607300859-R18","doi-asserted-by":"publisher","first-page":"26","DOI":"10.4103\/apjon.apjon_72_17","article-title":"Hospice and palliative care in China: development and challenges.","volume":"5","author":"Lu","year":"2018","journal-title":"Asia Pac J Oncol Nurs"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R19","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1186\/s12904-025-01891-3","article-title":"How does the general public perceive hospice and palliative care? An empirical study from China.","volume":"24","author":"Tang","year":"2025","journal-title":"BMC Palliat Care"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R20","doi-asserted-by":"publisher","first-page":"6592","DOI":"10.3390\/ijerph17186592","article-title":"Preference for aggressive end-of-life care among advanced cancer patients in Wuhan, China: a cross-sectional study.","volume":"17","author":"Liao","year":"2020","journal-title":"Int J Environ Res Public Health"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R21","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1634\/theoncologist.2016-0013","article-title":"Chemotherapy near the end of life for Chinese patients with solid malignancies.","volume":"22","author":"Sheng","year":"2017","journal-title":"Oncologist"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R22","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1186\/s12885-018-5237-1","article-title":"Geographical disparities in treatment and health care costs for end-of-life cancer patients in China: a retrospective study.","volume":"19","author":"Leng","year":"2019","journal-title":"BMC Cancer"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R23","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.1200\/JCO.2003.03.059","article-title":"Identifying potential indicators of the quality of end-of-life cancer care from administrative data.","volume":"21","author":"Earle","year":"2003","journal-title":"J Clin Oncol"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R24","doi-asserted-by":"publisher","first-page":"102561","DOI":"10.1016\/j.eclinm.2024.102561","article-title":"Prevalence of aggressive care among patients with cancer near the end of life: a systematic review and meta-analysis.","volume":"71","author":"Ma","year":"2024","journal-title":"EClinicalMedicine"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R25","doi-asserted-by":"publisher","first-page":"e041302","DOI":"10.1136\/bmjopen-2020-041302","article-title":"Incidence, comorbidity and mortality in patients with necrotising soft-tissue infections, 2005\u20132018: a Danish nationwide register-based cohort study.","volume":"10","author":"Hedetoft","year":"2020","journal-title":"BMJ Open"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R26","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1016\/0895-4356(94)90129-5","article-title":"Validation of a combined comorbidity index.","volume":"47","author":"Charlson","year":"1994","journal-title":"J Clin Epidemiol"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R27","unstructured":"Amin MB, Edge SB, Greene FL, Byrd DR, Brookland RK, Washington MK,\n                      et al\n                      . AJCC Cancer Staging Manual. 8th ed. Cham: Springer International Publishing; 2017."},{"key":"key-10.7189\/jogh.16.04258-202607300859-R28","unstructured":"National Cancer Institute. Metastatic cancer: when cancer spreads. Available: https:\/\/www.cancer.gov\/types\/metastatic-cancer. Accessed: 12 May 2026."},{"key":"key-10.7189\/jogh.16.04258-202607300859-R29","doi-asserted-by":"publisher","first-page":"e230394","DOI":"10.1001\/jamanetworkopen.2023.0394","article-title":"Incidence of aggressive end-of-life care among older adults with metastatic cancer living in nursing homes and community settings.","volume":"6","author":"Koroukian","year":"2023","journal-title":"JAMA Netw Open"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R30","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1186\/s12904-019-0419-4","article-title":"Multicentre analysis of intensity of care at the end-of-life in patients with advanced cancer, combining health administrative data with hospital records: variations in practice call for routine quality evaluation.","volume":"18","author":"Colombet","year":"2019","journal-title":"BMC Palliat Care"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R31","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.jss.2020.11.062","article-title":"A closer look into global hospital beds capacity and resource shortages during the COVID-19 pandemic.","volume":"260","author":"Sen-Crowe","year":"2021","journal-title":"J Surg Res"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R32","doi-asserted-by":"publisher","first-page":"djx028","DOI":"10.1093\/jnci\/djx028","article-title":"Aggressive end-of-life care for metastatic cancer patients younger than age 65 years.","volume":"109","author":"Falchook","year":"2017","journal-title":"J Natl Cancer Inst"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R33","doi-asserted-by":"publisher","first-page":"1106","DOI":"10.1016\/j.jpainsymman.2019.02.016","article-title":"Intensity of cancer care near the end of life at a tertiary care cancer center in Jordan.","volume":"57","author":"Abdel-Razeq","year":"2019","journal-title":"J Pain Symptom Manage"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R34","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1007\/s00134-024-07347-1","article-title":"Variation in intensive care unit beds capacity in China from 2007 to 2021.","volume":"50","author":"Yuan","year":"2024","journal-title":"Intensive Care Med"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R35","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1186\/s12904-024-01459-7","article-title":"Decreased aggressive care at the end of life among advanced cancer patients in the Republic of Korea: a nationwide study from 2012 to 2018.","volume":"23","author":"Kwon","year":"2024","journal-title":"BMC Palliat Care"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R36","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1089\/jpm.2015.0367","article-title":"Populations and interventions for palliative and end-of-life care: a systematic review.","volume":"19","author":"Singer","year":"2016","journal-title":"J Palliat Med"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R37","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1016\/j.jpainsymman.2010.06.010","article-title":"Chinese familial tradition and western influence: a case study in Singapore on decision making at the end of life.","volume":"40","author":"Ho","year":"2010","journal-title":"J Pain Symptom Manage"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R38","first-page":"27","article-title":"[Progress and development suggestions for per diem payment policy for hospice care in China].","volume":"41","author":"Wang","year":"2024","journal-title":"Health Econ Res"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R39","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1186\/s12904-025-01877-1","article-title":"Developing supportive policy environments for hospice care in China: a quantitative policy evaluation based on the PMC-index model.","volume":"24","author":"Li","year":"2025","journal-title":"BMC Palliat Care"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R40","doi-asserted-by":"publisher","first-page":"e228788","DOI":"10.1001\/jamanetworkopen.2022.8788","article-title":"Preferences for end-of-life care among patients with terminal cancer in China.","volume":"5","author":"Leng","year":"2022","journal-title":"JAMA Netw Open"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R41","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1016\/S0140-6736(21)02314-X","article-title":"Report of the Lancet Commission on the value of death: bringing death back into life.","volume":"399","author":"Sallnow","year":"2022","journal-title":"Lancet"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R42","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1007\/s00520-015-2885-4","article-title":"Factors associated with aggressive end of life cancer care.","volume":"24","author":"Henson","year":"2016","journal-title":"Support Care Cancer"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R43","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1016\/j.jpainsymman.2020.08.040","article-title":"Palliative care in the Greater China region: a systematic review of needs, models, and outcomes.","volume":"61","author":"Chung","year":"2021","journal-title":"J Pain Symptom Manage"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R44","doi-asserted-by":"publisher","first-page":"1967","DOI":"10.1016\/S0140-6736(22)01546-X","article-title":"The path to healthy ageing in China: a Peking University-Lancet Commission.","volume":"400","author":"Chen","year":"2022","journal-title":"Lancet"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R45","doi-asserted-by":"publisher","first-page":"11918","DOI":"10.21037\/apm-21-3228","article-title":"Is there a need for advance care planning in China? An interview survey of healthcare professionals in the neurology department.","volume":"10","author":"Huang","year":"2021","journal-title":"Ann Palliat Med"},{"key":"key-10.7189\/jogh.16.04258-202607300859-R46","doi-asserted-by":"publisher","first-page":"1354","DOI":"10.1186\/s12889-020-09463-1","article-title":"Disparities in end-of-life care, expenditures, and place of death by health insurance among cancer patients in China: a population-based, retrospective study.","volume":"20","author":"Li","year":"2020","journal-title":"BMC Public Health"}],"container-title":["Journal of Global Health"],"original-title":[],"link":[{"URL":"https:\/\/jogh.org\/2026\/jogh-16-04258","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T07:00:16Z","timestamp":1785481216000},"score":1,"resource":{"primary":{"URL":"https:\/\/jogh.org\/2026\/jogh-16-04258"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,31]]},"references-count":46,"URL":"https:\/\/doi.org\/10.7189\/jogh.16.04258","relation":{},"ISSN":["2047-2978","2047-2986"],"issn-type":[{"value":"2047-2978","type":"print"},{"value":"2047-2986","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,31]]},"article-number":"04258"}}