{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T19:19:48Z","timestamp":1767208788896,"version":"build-2238731810"},"posted":{"date-parts":[[2019,1,24]]},"group-title":"PeerJ Preprints","reference-count":0,"publisher":"PeerJ","license":[{"start":{"date-parts":[[2019,1,24]],"date-time":"2019-01-24T00:00:00Z","timestamp":1548288000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Mitochondrial DNA (mtDNA) presents several characteristics useful for forensic studies, especially related to the lack of recombination, to a high copy number, and to matrilineal inheritance. mtDNA typing based on sequences of the control region or full genomic sequences analysis is used to analyze a variety of forensicsamples such as old bones, teeth and hair, as well as other biological samples where the DNA content is low. Evaluation and reporting of the results requires careful consideration of biological issues as well as other issues such as nomenclature and reference population databases. In this work we review mitochondrial DNA profiling methods used for human identification and present their use in the main cases of human identification focusing on the most relevant issues for the forensic and medico-legal areas.<\/jats:p>","DOI":"10.7287\/peerj.preprints.27500v1","type":"posted-content","created":{"date-parts":[[2019,1,24]],"date-time":"2019-01-24T09:10:50Z","timestamp":1548321050000},"source":"Crossref","is-referenced-by-count":0,"title":["Mitochondrial DNA in human identification: a review"],"prefix":"10.7287","author":[{"given":"Ant\u00f3nio","family":"Amorim","sequence":"first","affiliation":[{"name":"Instituto Nacional de Medicina Legal e Ci\u00eancias Forenses, Lisbon, Portugal"}]},{"given":"Teresa","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Biologia, Universidade de \u00c9vora, \u00c9vora, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0176-5585","authenticated-orcid":true,"given":"Nuno","family":"Taveira","sequence":"additional","affiliation":[{"name":"Instituto Universit\u00e1rio Egas Moniz (IUEM), Almada, Portugal"},{"name":"Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisbon, Portugal"}]}],"member":"4443","container-title":[],"original-title":[],"link":[{"URL":"https:\/\/peerj.com\/preprints\/27500v1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/peerj.com\/preprints\/27500v1.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/peerj.com\/preprints\/27500v1.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/peerj.com\/preprints\/27500v1.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,12,23]],"date-time":"2019-12-23T20:20:14Z","timestamp":1577132414000},"score":1,"resource":{"primary":{"URL":"https:\/\/peerj.com\/preprints\/27500v1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,24]]},"references-count":0,"aliases":["10.7287\/peerj.preprints.27500"],"URL":"https:\/\/doi.org\/10.7287\/peerj.preprints.27500v1","relation":{},"subject":[],"published":{"date-parts":[[2019,1,24]]},"subtype":"preprint"}}