{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:35:08Z","timestamp":1777581308056,"version":"3.51.4"},"reference-count":22,"publisher":"American College of Physicians","issue":"12","license":[{"start":{"date-parts":[[2016,12,20]],"date-time":"2016-12-20T00:00:00Z","timestamp":1482192000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.acpjournals.org\/journal\/aim\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/100000199","name":"U.S. Department of Agriculture","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["U01AG022376"],"award-info":[{"award-number":["U01AG022376"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["R24HD065688"],"award-info":[{"award-number":["R24HD065688"]}],"id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["U01AG22376"],"award-info":[{"award-number":["U01AG22376"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["P30AG028740"],"award-info":[{"award-number":["P30AG028740"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["P30AG21332"],"award-info":[{"award-number":["P30AG21332"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["P30AG031679"],"award-info":[{"award-number":["P30AG031679"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["P30AG024827"],"award-info":[{"award-number":["P30AG024827"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["P30AG021342"],"award-info":[{"award-number":["P30AG021342"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["K07AG3587"],"award-info":[{"award-number":["K07AG3587"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1RR025744"],"award-info":[{"award-number":["UL1RR025744"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["U54RR025208"],"award-info":[{"award-number":["U54RR025208"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR000142"],"award-info":[{"award-number":["UL1TR000142"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Intern Med"],"published-print":{"date-parts":[[2016,12,20]]},"DOI":"10.7326\/m16-0529","type":"journal-article","created":{"date-parts":[[2018,1,31]],"date-time":"2018-01-31T20:30:52Z","timestamp":1517430652000},"page":"833-840","source":"Crossref","is-referenced-by-count":29,"title":["Effect of Structured Physical Activity on Overall Burden and Transitions Between States of Major Mobility Disability in Older Persons"],"prefix":"10.7326","volume":"165","author":[{"given":"Thomas M.","family":"Gill","sequence":"first","affiliation":[{"name":"From Yale School of Medicine, New Haven, Connecticut; University of Maryland School of Medicine, Baltimore, Maryland; University of Florida, Gainesville, Florida; Pennington Biomedical Research Center, Baton Rouge, Louisiana; Tufts University, Boston, Massachusetts; Stanford School of Medicine, Stanford, California; Wake Forest University and Wake Forest School of Medicine, Winston-Salem, North Carolina; University of Pittsburgh, Pittsburgh, Pennsylvania;"},{"name":"and Northwestern University Feinberg School of Medicine, Chicago, Illinois."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jack M.","family":"Guralnik","sequence":"additional","affiliation":[{"name":"From Yale School of Medicine, New Haven, Connecticut; University of Maryland School of Medicine, Baltimore, Maryland; University of Florida, Gainesville, Florida; Pennington Biomedical Research Center, Baton Rouge, Louisiana; Tufts University, Boston, Massachusetts; Stanford School of Medicine, Stanford, California; Wake Forest University and Wake Forest School of Medicine, Winston-Salem, North Carolina; University of Pittsburgh, Pittsburgh, Pennsylvania;"},{"name":"and Northwestern University Feinberg School of Medicine, Chicago, Illinois."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Pahor","sequence":"additional","affiliation":[{"name":"From Yale School of Medicine, New Haven, Connecticut; University of Maryland School of Medicine, Baltimore, Maryland; University of Florida, Gainesville, Florida; Pennington Biomedical Research Center, Baton Rouge, Louisiana; Tufts University, Boston, Massachusetts; Stanford School of Medicine, Stanford, California; Wake Forest University and Wake Forest School of Medicine, Winston-Salem, North Carolina; University of Pittsburgh, Pittsburgh, Pennsylvania;"},{"name":"and Northwestern University Feinberg School of Medicine, Chicago, Illinois."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy","family":"Church","sequence":"additional","affiliation":[{"name":"From Yale School of Medicine, New Haven, Connecticut; University of Maryland School of Medicine, Baltimore, Maryland; University of Florida, Gainesville, Florida; Pennington Biomedical Research Center, Baton Rouge, Louisiana; Tufts University, Boston, Massachusetts; Stanford School of Medicine, Stanford, California; Wake Forest University and Wake Forest School of Medicine, Winston-Salem, North Carolina; University of Pittsburgh, Pittsburgh, Pennsylvania;"},{"name":"and Northwestern University Feinberg School of Medicine, Chicago, Illinois."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger A.","family":"Fielding","sequence":"additional","affiliation":[{"name":"From Yale School of Medicine, New Haven, Connecticut; University of Maryland School of Medicine, Baltimore, Maryland; University of Florida, Gainesville, Florida; Pennington Biomedical Research Center, Baton Rouge, Louisiana; Tufts University, Boston, Massachusetts; Stanford School of Medicine, Stanford, California; Wake Forest University and Wake Forest School of Medicine, Winston-Salem, North Carolina; University of Pittsburgh, Pittsburgh, Pennsylvania;"},{"name":"and Northwestern University Feinberg School of Medicine, Chicago, Illinois."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abby C.","family":"King","sequence":"additional","affiliation":[{"name":"From Yale School of Medicine, New Haven, Connecticut; University of Maryland School of Medicine, Baltimore, Maryland; University of Florida, Gainesville, Florida; Pennington Biomedical Research Center, Baton Rouge, Louisiana; Tufts University, Boston, Massachusetts; Stanford School of Medicine, Stanford, California; Wake Forest University and Wake Forest School of Medicine, Winston-Salem, North Carolina; University of Pittsburgh, Pittsburgh, Pennsylvania;"},{"name":"and Northwestern University Feinberg School of Medicine, Chicago, Illinois."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony P.","family":"Marsh","sequence":"additional","affiliation":[{"name":"From Yale School of Medicine, New Haven, Connecticut; University of Maryland School of Medicine, Baltimore, Maryland; University of Florida, Gainesville, Florida; Pennington Biomedical Research Center, Baton Rouge, Louisiana; Tufts University, Boston, Massachusetts; Stanford School of Medicine, Stanford, California; Wake Forest University and Wake Forest School of Medicine, Winston-Salem, North Carolina; University of Pittsburgh, Pittsburgh, Pennsylvania;"},{"name":"and Northwestern University Feinberg School of Medicine, Chicago, Illinois."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne B.","family":"Newman","sequence":"additional","affiliation":[{"name":"From Yale School of Medicine, New Haven, Connecticut; University of Maryland School of Medicine, Baltimore, Maryland; University of Florida, Gainesville, Florida; Pennington Biomedical Research Center, Baton Rouge, Louisiana; Tufts University, Boston, Massachusetts; Stanford School of Medicine, Stanford, California; Wake Forest University and Wake Forest School of Medicine, Winston-Salem, North Carolina; University of Pittsburgh, Pittsburgh, Pennsylvania;"},{"name":"and Northwestern University Feinberg School of Medicine, Chicago, Illinois."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine A.","family":"Pellegrini","sequence":"additional","affiliation":[{"name":"From Yale School of Medicine, New Haven, Connecticut; University of Maryland School of Medicine, Baltimore, Maryland; University of Florida, Gainesville, Florida; Pennington Biomedical Research Center, Baton Rouge, Louisiana; Tufts University, Boston, Massachusetts; Stanford School of Medicine, Stanford, California; Wake Forest University and Wake Forest School of Medicine, Winston-Salem, North Carolina; University of Pittsburgh, Pittsburgh, Pennsylvania;"},{"name":"and Northwestern University Feinberg School of Medicine, Chicago, Illinois."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shyh-Huei","family":"Chen","sequence":"additional","affiliation":[{"name":"From Yale School of Medicine, New Haven, Connecticut; University of Maryland School of Medicine, Baltimore, Maryland; University of Florida, Gainesville, Florida; Pennington Biomedical Research Center, Baton Rouge, Louisiana; Tufts University, Boston, Massachusetts; Stanford School of Medicine, Stanford, California; Wake Forest University and Wake Forest School of Medicine, Winston-Salem, North Carolina; University of Pittsburgh, Pittsburgh, Pennsylvania;"},{"name":"and Northwestern University Feinberg School of Medicine, Chicago, Illinois."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heather G.","family":"Allore","sequence":"additional","affiliation":[{"name":"From Yale School of Medicine, New Haven, Connecticut; University of Maryland School of Medicine, Baltimore, Maryland; University of Florida, Gainesville, Florida; Pennington Biomedical Research Center, Baton Rouge, Louisiana; Tufts University, Boston, Massachusetts; Stanford School of Medicine, Stanford, California; Wake Forest University and Wake Forest School of Medicine, Winston-Salem, North Carolina; University of Pittsburgh, Pittsburgh, Pennsylvania;"},{"name":"and Northwestern University Feinberg School of Medicine, Chicago, Illinois."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael E.","family":"Miller","sequence":"additional","affiliation":[{"name":"From Yale School of Medicine, New Haven, Connecticut; University of Maryland School of Medicine, Baltimore, Maryland; University of Florida, Gainesville, Florida; Pennington Biomedical Research Center, Baton Rouge, Louisiana; Tufts University, Boston, Massachusetts; Stanford School of Medicine, Stanford, California; Wake Forest University and Wake Forest School of Medicine, Winston-Salem, North Carolina; University of Pittsburgh, Pittsburgh, Pennsylvania;"},{"name":"and Northwestern University Feinberg School of Medicine, Chicago, Illinois."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"for the LIFE Study Investigators*","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4285","reference":[{"key":"r1-M160529","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1997.tb00986.x"},{"key":"r3-M160529","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-010-1543-2"},{"key":"r4-M160529","doi-asserted-by":"publisher","DOI":"10.1097\/00019442-200105000-00003"},{"key":"r5-M160529","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.5616"},{"key":"r6-M160529","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2004.52570.x"},{"key":"r7-M160529","doi-asserted-by":"publisher","DOI":"10.1046\/j.1532-5415.2003.51114.x"},{"key":"r8-M160529","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glt064"},{"key":"r9-M160529","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glr123"},{"key":"r10-M160529","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwi083"},{"key":"r11-M160529","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2005.00586.x"},{"key":"r12-M160529","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199503023320902"},{"key":"r13-M160529","first-page":"314","volume":"48","author":"Teng EL","year":"1987","journal-title":"J Clin Psychiatry"},{"key":"r14-M160529","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S49737"},{"key":"r15-M160529","doi-asserted-by":"publisher","DOI":"10.1002\/sim.2712"},{"key":"r16-M160529","doi-asserted-by":"publisher","DOI":"10.1177\/0962280208092301"},{"key":"r17-M160529","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v038.i08"},{"key":"r18-M160529","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-156-2-201201170-00009"},{"key":"r19-M160529","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.1568"},{"key":"r20-M160529","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/60.8.1013"},{"key":"r21-M160529","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1997.03540250033028"},{"key":"r22-M160529","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.17.2018"},{"key":"r23-M160529","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1994.03520130074036"}],"container-title":["Annals of Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.acpjournals.org\/doi\/pdf\/10.7326\/M16-0529","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.acpjournals.org\/doi\/full-xml\/10.7326\/M16-0529","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/annals.org\/article.aspx?doi=10.7326\/M16-0529","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,9]],"date-time":"2025-02-09T13:10:39Z","timestamp":1739106639000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.acpjournals.org\/doi\/10.7326\/M16-0529"}},"subtitle":["Secondary Analysis of a Randomized Trial"],"short-title":[],"issued":{"date-parts":[[2016,12,20]]},"references-count":22,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,12,20]]}},"alternative-id":["10.7326\/M16-0529"],"URL":"https:\/\/doi.org\/10.7326\/m16-0529","relation":{},"ISSN":["0003-4819","1539-3704"],"issn-type":[{"value":"0003-4819","type":"print"},{"value":"1539-3704","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,20]]}}}