{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T16:18:16Z","timestamp":1790957896206,"version":"4.1.0"},"reference-count":27,"publisher":"American College of Physicians","issue":"7","license":[{"start":{"date-parts":[[2018,4,3]],"date-time":"2018-04-03T00:00:00Z","timestamp":1522713600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.acpjournals.org\/journal\/aim\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/100008272","name":"Novartis Pharmaceuticals Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008272","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Intern Med"],"published-print":{"date-parts":[[2018,4,3]]},"DOI":"10.7326\/m17-1094","type":"journal-article","created":{"date-parts":[[2018,2,19]],"date-time":"2018-02-19T23:32:52Z","timestamp":1519083172000},"page":"461-470","source":"Crossref","is-referenced-by-count":120,"title":["Treatment-Free Remission After Second-Line Nilotinib Treatment in Patients With Chronic Myeloid Leukemia in Chronic Phase"],"prefix":"10.7326","volume":"168","author":[{"given":"Fran\u00e7ois-Xavier","family":"Mahon","sequence":"first","affiliation":[{"name":"University of Bordeaux, Bordeaux, France (F.M.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"Boquimpani","sequence":"additional","affiliation":[{"name":"Hemocentro do Rio de Janeiro, HEMORIO, Rio de Janeiro, Brazil (C.B.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Wook","family":"Kim","sequence":"additional","affiliation":[{"name":"The Catholic University of Korea, Seoul, South Korea (D.K.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noam","family":"Benyamini","sequence":"additional","affiliation":[{"name":"Rambam Health Care Campus, Haifa, Israel (N.B.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelma Cristina D.","family":"Clementino","sequence":"additional","affiliation":[{"name":"Hospital Das Clinicas da Universidade Federal de Minas Gerais, Belo Horizonte, Brazil (N.C.C.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasily","family":"Shuvaev","sequence":"additional","affiliation":[{"name":"Russian Research Institute of Hematology and Transfusiology, Saint Petersburg, Russia (V.S.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sikander","family":"Ailawadhi","sequence":"additional","affiliation":[{"name":"Mayo Clinic, Jacksonville, Florida (S.A.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey Howard","family":"Lipton","sequence":"additional","affiliation":[{"name":"University of Toronto, Toronto, Ontario, Canada (J.H.L.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna G.","family":"Turkina","sequence":"additional","affiliation":[{"name":"National Research Center for Hematology, Moscow, Russia (A.G.T.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel","family":"De Paz","sequence":"additional","affiliation":[{"name":"University Hospital La Paz, Madrid, Spain (R.D.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"Moiraghi","sequence":"additional","affiliation":[{"name":"Hospital General De Agudos J. M. Ramos Mejia, Buenos Aires, Argentina (B.M.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franck E.","family":"Nicolini","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Lyon Sud, Pierre-B\u00e9nite, France (F.E.N.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jolanta","family":"Dengler","sequence":"additional","affiliation":[{"name":"Onkologische Praxis Heilbronn, Heilbronn, Germany (J.D.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomasz","family":"Sacha","sequence":"additional","affiliation":[{"name":"Jagiellonian University Hospital, Krak\u00f3w, Poland (T.S.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoto","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Akita University Hospital, Akita, Japan (N.T.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafik","family":"Fellague-Chebra","sequence":"additional","affiliation":[{"name":"Novartis Pharma SAS, Rueil-Malmaison, France (R.F.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandip","family":"Acharya","sequence":"additional","affiliation":[{"name":"Novartis Healthcare Pvt Ltd, Hyderabad, India (S.A.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephane","family":"Wong","sequence":"additional","affiliation":[{"name":"Novartis Oncology Precision Medicine, Cambridge, Massachusetts (S.W.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Jin","sequence":"additional","affiliation":[{"name":"Novartis Pharmaceuticals Corporation, East Hanover, New Jersey (Y.J.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy P.","family":"Hughes","sequence":"additional","affiliation":[{"name":"University of Adelaide, Adelaide, South Australia, Australia (T.P.H.)"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4285","reference":[{"key":"r1-M171094","first-page":"1497","volume":"132","author":"Nowell PC","year":"1960","journal-title":"Science"},{"key":"r2-M171094","doi-asserted-by":"publisher","DOI":"10.1038\/243290a0"},{"key":"r3-M171094","doi-asserted-by":"publisher","DOI":"10.1038\/306277a0"},{"key":"r4-M171094","doi-asserted-by":"publisher","DOI":"10.1126\/science.2406902"},{"key":"r5-M171094","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1609324"},{"key":"r6-M171094","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199904293401706"},{"key":"r7-M171094","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.66.2866"},{"key":"r9-M171094","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2015.29"},{"key":"r10-M171094","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-05-501569"},{"key":"r12-M171094","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2015.139899"},{"key":"r14-M171094","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(10)70233-3"},{"key":"r15-M171094","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2016.68.2914"},{"key":"r16-M171094","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.48.5797"},{"key":"r17-M171094","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-02-483750"},{"key":"r21-M171094","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(15)00196-9"},{"issue":"101","key":"r22-M171094","first-page":"Abstract no. P2","volume":"61","author":"Takahashi N","year":"2016","journal-title":"Haematologica"},{"key":"r23-M171094","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-12-544015"},{"key":"r25-M171094","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2011.056853"},{"key":"r26-M171094","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-01-694265"},{"key":"r28-M171094","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2016.5"},{"key":"r29-M171094","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2015.270"},{"key":"r30-M171094","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.55.6910"},{"key":"r32-M171094","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.56.3858"},{"key":"r34-M171094","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2016.115"},{"key":"r35-M171094","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdx219"},{"key":"r39-M171094","first-page":"1","author":"Park JS","year":"2015","journal-title":"Leuk Lymphoma"},{"key":"r41-M171094","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.21.8230"}],"container-title":["Annals of Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.acpjournals.org\/doi\/pdf\/10.7326\/M17-1094","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.acpjournals.org\/doi\/full-xml\/10.7326\/M17-1094","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/annals.org\/article.aspx?doi=10.7326\/M17-1094","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,9]],"date-time":"2025-02-09T13:00:20Z","timestamp":1739106020000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.acpjournals.org\/doi\/10.7326\/M17-1094"}},"subtitle":["Results From a Single-Group, Phase 2, Open-Label Study"],"short-title":[],"issued":{"date-parts":[[2018,4,3]]},"references-count":27,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,4,3]]}},"alternative-id":["10.7326\/M17-1094"],"URL":"https:\/\/doi.org\/10.7326\/m17-1094","relation":{},"ISSN":["0003-4819","1539-3704"],"issn-type":[{"value":"0003-4819","type":"print"},{"value":"1539-3704","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,3]]}}}