{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T05:31:37Z","timestamp":1788931897034,"version":"build-2803163510"},"reference-count":47,"publisher":"American College of Physicians","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Intern Med"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.7326\/m21-4653","type":"journal-article","created":{"date-parts":[[2022,8,15]],"date-time":"2022-08-15T21:01:21Z","timestamp":1660597281000},"page":"1230-1239","source":"Crossref","is-referenced-by-count":13,"title":["Left Atrial Appendage Occlusion Versus Oral Anticoagulation in Atrial Fibrillation"],"prefix":"10.7326","volume":"175","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3539-7485","authenticated-orcid":false,"given":"Derek S.","family":"Chew","sequence":"first","affiliation":[{"name":"Duke Clinical Research Institute, Duke University, Durham, North Carolina, and Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada (D.S.C.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Zhou","sequence":"additional","affiliation":[{"name":"Duke-National University of Singapore Medical School, Singapore (K.Z.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4345-0816","authenticated-orcid":false,"given":"Sean D.","family":"Pokorney","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Duke University, and Division of Cardiology, Duke University Medical Center, Durham, North Carolina (S.D.P., S.V., M.R.P., J.P.P.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3020-2108","authenticated-orcid":false,"given":"David B.","family":"Matchar","sequence":"additional","affiliation":[{"name":"Duke-National University of Singapore Medical School, Singapore, and Division of General Internal Medicine, Duke University Medical Center, Durham, North Carolina (D.B.M.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sreekanth","family":"Vemulapalli","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Duke University, and Division of Cardiology, Duke University Medical Center, Durham, North Carolina (S.D.P., S.V., M.R.P., J.P.P.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2540-3095","authenticated-orcid":false,"given":"Larry A.","family":"Allen","sequence":"additional","affiliation":[{"name":"University of Colorado School of Medicine, Aurora, Colorado (L.A.A.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin P.","family":"Jackson","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Duke University Medical Center, Durham, North Carolina (K.P.J.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zainab","family":"Samad","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Duke University Medical Center, Durham, North Carolina, and Department of Medicine, Aga Khan University, Karachi, Pakistan (Z.S.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manesh R.","family":"Patel","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Duke University, and Division of Cardiology, Duke University Medical Center, Durham, North Carolina (S.D.P., S.V., M.R.P., J.P.P.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James V.","family":"Freeman","sequence":"additional","affiliation":[{"name":"Yale University School of Medicine, New Haven, Connecticut (J.V.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0772-2404","authenticated-orcid":false,"given":"Jonathan P.","family":"Piccini","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Duke University, and Division of Cardiology, Duke University Medical Center, Durham, North Carolina (S.D.P., S.V., M.R.P., J.P.P.)"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4285","reference":[{"key":"r1-M214653","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw330"},{"key":"r2-M214653","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.04.029"},{"key":"r3-M214653","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.15192"},{"key":"r4-M214653","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.04.067"},{"key":"r5-M214653","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2015.0374"},{"key":"r6-M214653","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.1371"},{"key":"r7-M214653","doi-asserted-by":"publisher","DOI":"10.1177\/0272989X15593083"},{"key":"r8-M214653","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-016-0351-y"},{"key":"r9-M214653","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61343-X"},{"key":"r10-M214653","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2013.01.009"},{"key":"r11-M214653","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e31826d5fe8"},{"key":"r12-M214653","doi-asserted-by":"publisher","DOI":"10.1177\/1747493020974561"},{"key":"r13-M214653","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.10.021"},{"key":"r14-M214653","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.19.2441"},{"key":"r15-M214653","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)62343-0"},{"key":"r16-M214653","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2013.05.011"},{"key":"r17-M214653","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.118.011577"},{"key":"r18-M214653","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.10.010"},{"key":"r19-M214653","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.10.946"},{"key":"r21-M214653","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu006"},{"key":"r22-M214653","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2013.12.011"},{"key":"r23-M214653","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d124"},{"key":"r24-M214653","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.09.024"},{"key":"r25-M214653","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1105575"},{"key":"r26-M214653","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182a9f45f"},{"key":"r27-M214653","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.526988"},{"key":"r28-M214653","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.115.009779"},{"key":"r29-M214653","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(98)00151-6"},{"key":"r30-M214653","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2016-309782"},{"key":"r31-M214653","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.08.089"},{"key":"r32-M214653","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-010-9591-y"},{"key":"r33-M214653","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.115.011979"},{"key":"r34-M214653","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-151-5-200909010-00003"},{"key":"r35-M214653","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs292"},{"key":"r36-M214653","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv476"},{"key":"r37-M214653","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.119.006212"},{"key":"r38-M214653","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2017.06.110"},{"key":"r39-M214653","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euv421"},{"key":"r40-M214653","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa612"},{"key":"r41-M214653","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000665"},{"key":"r42-M214653","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2020.10.044"},{"key":"r43-M214653","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euz258"},{"key":"r44-M214653","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60986-6"},{"key":"r45-M214653","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-19-01027"},{"key":"r46-M214653","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-18-00344"},{"key":"r47-M214653","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw077"},{"key":"r48-M214653","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2017.11.046"}],"container-title":["Annals of Internal Medicine"],"original-title":[],"language":"en","deposited":{"date-parts":[[2022,9,19]],"date-time":"2022-09-19T21:03:07Z","timestamp":1663621387000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.acpjournals.org\/doi\/10.7326\/M21-4653"}},"subtitle":["A Decision Analysis"],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":47,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.7326\/M21-4653"],"URL":"https:\/\/doi.org\/10.7326\/m21-4653","relation":{},"ISSN":["0003-4819","1539-3704"],"issn-type":[{"value":"0003-4819","type":"print"},{"value":"1539-3704","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9]]}}}