{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T13:37:00Z","timestamp":1792417020964,"version":"4.4.0"},"reference-count":22,"publisher":"American College of Physicians","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Intern Med"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.7326\/m22-0988","type":"journal-article","created":{"date-parts":[[2022,8,22]],"date-time":"2022-08-22T17:00:28Z","timestamp":1661187628000},"page":"1250-1257","source":"Crossref","is-referenced-by-count":68,"title":["Risk for Myocardial Infarction, Stroke, and Pulmonary Embolism Following COVID-19 Vaccines in Adults Younger Than 75 Years in France"],"prefix":"10.7326","volume":"175","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4814-6370","authenticated-orcid":false,"given":"J\u00e9r\u00e9mie","family":"Botton","sequence":"first","affiliation":[{"name":"EPI-PHARE Scientific Interest Group in Epidemiology of Health Products (French National Agency for the Safety of Medicines and Health Products \u2013 ANSM, French National Health Insurance \u2013 CNAM), Saint-Denis, France, and Facult\u00e9 de Pharmacie, Universit\u00e9 Paris-Saclay, Ch\u00e2tenay-Malabry, France (J.B.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7946-7759","authenticated-orcid":false,"given":"Marie Joelle","family":"Jabagi","sequence":"additional","affiliation":[{"name":"EPI-PHARE Scientific Interest Group in Epidemiology of Health Products (French National Agency for the Safety of Medicines and Health Products \u2013 ANSM, French National Health Insurance - CNAM), Saint-Denis, France (M.J.J., M.B., B.B., J.D., S.L.V., A.W., R.D.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4115-7093","authenticated-orcid":false,"given":"Marion","family":"Bertrand","sequence":"additional","affiliation":[{"name":"EPI-PHARE Scientific Interest Group in Epidemiology of Health Products (French National Agency for the Safety of Medicines and Health Products \u2013 ANSM, French National Health Insurance - CNAM), Saint-Denis, France (M.J.J., M.B., B.B., J.D., S.L.V., A.W., R.D.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5835-7668","authenticated-orcid":false,"given":"B\u00e9rang\u00e8re","family":"Baricault","sequence":"additional","affiliation":[{"name":"EPI-PHARE Scientific Interest Group in Epidemiology of Health Products (French National Agency for the Safety of Medicines and Health Products \u2013 ANSM, French National Health Insurance - CNAM), Saint-Denis, France (M.J.J., M.B., B.B., J.D., S.L.V., A.W., R.D.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2017-7041","authenticated-orcid":false,"given":"J\u00e9r\u00f4me","family":"Drouin","sequence":"additional","affiliation":[{"name":"EPI-PHARE Scientific Interest Group in Epidemiology of Health Products (French National Agency for the Safety of Medicines and Health Products \u2013 ANSM, French National Health Insurance - CNAM), Saint-Denis, France (M.J.J., M.B., B.B., J.D., S.L.V., A.W., R.D.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1303-8281","authenticated-orcid":false,"given":"St\u00e9phane","family":"Le Vu","sequence":"additional","affiliation":[{"name":"EPI-PHARE Scientific Interest Group in Epidemiology of Health Products (French National Agency for the Safety of Medicines and Health Products \u2013 ANSM, French National Health Insurance - CNAM), Saint-Denis, France (M.J.J., M.B., B.B., J.D., S.L.V., A.W., R.D.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8687-9092","authenticated-orcid":false,"given":"Alain","family":"Weill","sequence":"additional","affiliation":[{"name":"EPI-PHARE Scientific Interest Group in Epidemiology of Health Products (French National Agency for the Safety of Medicines and Health Products \u2013 ANSM, French National Health Insurance - CNAM), Saint-Denis, France (M.J.J., M.B., B.B., J.D., S.L.V., A.W., R.D.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paddy","family":"Farrington","sequence":"additional","affiliation":[{"name":"School of Mathematics and Statistics, The Open University, Milton Keynes, United Kingdom (P.F.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8393-4217","authenticated-orcid":false,"given":"Mahmoud","family":"Zureik","sequence":"additional","affiliation":[{"name":"EPI-PHARE Scientific Interest Group in Epidemiology of Health Products (French National Agency for the Safety of Medicines and Health Products - ANSM, French National Health Insurance - CNAM), Saint-Denis, France, and University Paris-Saclay, UVSQ, Univ. Paris-Sud, Inserm, Anti-infective evasion and pharmacoepidemiology, CESP, Montigny le Bretonneux, France (M.Z.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7646-3667","authenticated-orcid":false,"given":"Rosemary","family":"Dray-Spira","sequence":"additional","affiliation":[{"name":"EPI-PHARE Scientific Interest Group in Epidemiology of Health Products (French National Agency for the Safety of Medicines and Health Products \u2013 ANSM, French National Health Insurance - CNAM), Saint-Denis, France (M.J.J., M.B., B.B., J.D., S.L.V., A.W., R.D.)"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4285","reference":[{"key":"r1-M220988","doi-asserted-by":"publisher","DOI":"10.2147\/IJGM.S324349"},{"key":"r2-M220988","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2021.102742"},{"key":"r3-M220988","doi-asserted-by":"publisher","DOI":"10.1007\/s40119-021-00248-0"},{"key":"r4-M220988","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2110475"},{"key":"r5-M220988","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00896-5"},{"key":"r6-M220988","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.21699"},{"key":"r7-M220988","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.15072"},{"key":"r8-M220988","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n1931"},{"key":"r9-M220988","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-021-01408-4"},{"key":"r10-M220988","doi-asserted-by":"crossref","unstructured":"Potteg\u00e5rd A, Lund LC, Karlstad \u00d8, et al.\n                      Arterial events, venous thromboembolism, thrombocytopenia, and bleeding after vaccination with Oxford-AstraZeneca ChAdOx1-S in Denmark and Norway: population based cohort study. BMJ. 2021;373:n1114. doi:10.1136\/bmj.n1114","DOI":"10.1136\/bmj.n1114"},{"key":"r11-M220988","doi-asserted-by":"crossref","unstructured":"Chui CSL, Fan M, Wan EYF, et al.\n                      Thromboembolic events and hemorrhagic stroke after mRNA (BNT162b2) and inactivated (CoronaVac) Covid-19 vaccination: a self-controlled case series study. eClinicalMedicine. 2022;50:101504. doi:10.1016\/j.eclinm.2022.101504","DOI":"10.1016\/j.eclinm.2022.101504"},{"key":"r12-M220988","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanepe.2021.100158"},{"key":"r13-M220988","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2021.666848"},{"key":"r14-M220988","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a008695"},{"key":"r15-M220988","doi-asserted-by":"publisher","DOI":"10.2307\/2533328"},{"key":"r16-M220988","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2016.04.050"},{"key":"r17-M220988","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000009180"},{"key":"r18-M220988","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2013.09.052"},{"key":"r19-M220988","doi-asserted-by":"publisher","DOI":"10.1002\/sim.9325"},{"key":"r20-M220988","doi-asserted-by":"publisher","DOI":"10.1093\/biostatistics\/kxn013"},{"key":"r21-M220988","doi-asserted-by":"crossref","unstructured":"Benjamini Y, Hochberg Y.\n                      Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Series B Stat Methodol. 1995;57:289-300. doi:10.1111\/j.2517-6161.1995.tb02031.x","DOI":"10.1111\/j.2517-6161.1995.tb02031.x"},{"key":"r22-M220988","doi-asserted-by":"crossref","unstructured":"Efron B.\n                      Large-scale simultaneous hypothesis testing: the choice of a null hypothesis. J Am Stat Assoc. 2004;99:96-104. doi:10.1198\/016214504000000089","DOI":"10.1198\/016214504000000089"}],"container-title":["Annals of Internal Medicine"],"original-title":[],"language":"en","deposited":{"date-parts":[[2022,9,19]],"date-time":"2022-09-19T17:03:04Z","timestamp":1663606984000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.acpjournals.org\/doi\/10.7326\/M22-0988"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":22,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.7326\/M22-0988"],"URL":"https:\/\/doi.org\/10.7326\/m22-0988","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.742288442.793595505","asserted-by":"object"}]},"ISSN":["0003-4819","1539-3704"],"issn-type":[{"value":"0003-4819","type":"print"},{"value":"1539-3704","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9]]}}}