{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T14:35:43Z","timestamp":1777646143049,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Glob Adv Health Med"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:p>\n                    People who suffer from recalcitrant chronic daily headache (CDH)\u2014a primary, episodic headache occurring at least 15 days per month, and lasting four or more hours per day for at least three consecutive months\n                    <jats:sup>1<\/jats:sup>\n                    \u2014have generally tried many pain relief medications with few positive results. These patients often continue to add more and more medications and travel from clinician to clinician seeking help, without relief. Patients with recalcitrant CDH are often caught in a vicious cycle of increasing pain which results in a substantial impact from their disease on productivity and quality of life. Studies in the United States and Europe indicate that four to five percent of the general population has recalcitrant CDH,\n                    <jats:sup>2<\/jats:sup>\n                    which encompasses transformed migraine and chronic tension-type headache.\n                    <jats:sup>3<\/jats:sup>\n                  <\/jats:p>\n                  <jats:p>\n                    The disability associated with recalcitrant CDH is substantial, as patients have a significantly diminished quality of life and mental health, as well as impaired physical, social, and occupational functioning.\n                    <jats:sup>4,5<\/jats:sup>\n                  <\/jats:p>\n                  <jats:p>\n                    Research shows that CDH may not be treated effectively with conventional medicine (CM). Integrative medicine (IM) offers a complex, personalized intervention necessary to treat CDH. Many integrative therapies have shown benefit, effectiveness, cost effectiveness and low side effect profile in patients with both chronic headache and chronic pain.\n                    <jats:sup>6\u201417<\/jats:sup>\n                    Yet even within the IM community, clinicians often struggle with the balance between providing evidence-based therapy and patient-centered, complex, personalized integrative approaches, which may use popular but unproven therapies.\n                  <\/jats:p>\n                  <jats:p>In this article, we present a series of cases comprising patients with CDH who had previously been recalcitrant to CM approaches. In each case, employing a five-pronged treatment algorithm resulted in the successful IM treatment of CDH. By using this five-pronged approach, clinicians can offer the standardized protocols and scientific rationale they are accustomed to when employing CM options while additionally offering the benefit of IM possibilities.<\/jats:p>","DOI":"10.7453\/gahmj.2014.002","type":"journal-article","created":{"date-parts":[[2014,12,30]],"date-time":"2014-12-30T07:39:25Z","timestamp":1419925165000},"page":"45-54","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["The Positive Impact of Integrative Medicine in the Treatment of Recalcitrant Chronic Daily Headache: A Series of Case Reports"],"prefix":"10.1177","volume":"3","author":[{"given":"Steve","family":"Amoils","sequence":"first","affiliation":[{"name":"The Alliance Institute for Integrative Medicine, Cincinnati, Ohio."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandi","family":"Amoils","sequence":"additional","affiliation":[{"name":"The Alliance Institute for Integrative Medicine, Cincinnati, Ohio."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiffany","family":"Lester","sequence":"additional","affiliation":[{"name":"The Alliance Institute for Integrative Medicine, Cincinnati, Ohio."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liz","family":"Woolford","sequence":"additional","affiliation":[{"name":"The Alliance Institute for Integrative Medicine, Cincinnati, Ohio."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Gallagher","sequence":"additional","affiliation":[{"name":"The Alliance Institute for Integrative Medicine, Cincinnati, Ohio."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,7,1]]},"reference":[{"key":"bibr1-gahmj.2014.002","doi-asserted-by":"publisher","DOI":"10.1007\/s10194-007-0418-3"},{"key":"bibr2-gahmj.2014.002","first-page":"885","volume":"6","author":"Silberstein SD","year":"2006","journal-title":"Johns Hopkins Advanced Studies in Medicine Proceedings."},{"key":"bibr3-gahmj.2014.002","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-001-0070-6"},{"issue":"4","key":"bibr4-gahmj.2014.002","first-page":"235","volume":"105","author":"Silberstein SD","year":"2005","journal-title":"J Am Osteopath Assoc."},{"key":"bibr5-gahmj.2014.002","doi-asserted-by":"publisher","DOI":"10.1177\/0333102411398400"},{"key":"bibr6-gahmj.2014.002","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2012.3654"},{"key":"bibr7-gahmj.2014.002","doi-asserted-by":"publisher","DOI":"10.1185\/174234306X112844"},{"key":"bibr8-gahmj.2014.002","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0b013e318208c8fe"},{"key":"bibr9-gahmj.2014.002","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38029.421863.EB"},{"key":"bibr10-gahmj.2014.002","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2007.01504.x"},{"key":"bibr11-gahmj.2014.002","doi-asserted-by":"publisher","DOI":"10.1177\/0333102411420585"},{"key":"bibr12-gahmj.2014.002","doi-asserted-by":"publisher","DOI":"10.1007\/s10194-011-0391-8"},{"key":"bibr13-gahmj.2014.002","doi-asserted-by":"publisher","DOI":"10.1089\/acm.2009.0673"},{"key":"bibr14-gahmj.2014.002","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2006.00535.x"},{"issue":"5","key":"bibr15-gahmj.2014.002","first-page":"322","volume":"78","author":"Hoyt WH","year":"1979","journal-title":"J Am Osteopath Assoc."},{"issue":"8","key":"bibr16-gahmj.2014.002","first-page":"403","volume":"109","author":"Schabert E","year":"2009","journal-title":"J Am Osteopath Assoc."},{"key":"bibr17-gahmj.2014.002","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6882-13-146"},{"key":"bibr18-gahmj.2014.002","volume-title":"Get well & stay well\u2014optimal health through transformational medicine.","author":"Amoils S","year":"2012"},{"key":"bibr19-gahmj.2014.002","unstructured":"Jones D editor. Textbook of functional medicine. Federal Way, WA: Institute for Functional Medicine; 2010: 462\u20138."}],"container-title":["Global Advances in Health and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.7453\/gahmj.2014.002","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.7453\/gahmj.2014.002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T06:34:25Z","timestamp":1777444465000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.7453\/gahmj.2014.002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["10.7453\/gahmj.2014.002"],"URL":"https:\/\/doi.org\/10.7453\/gahmj.2014.002","relation":{},"ISSN":["2164-957X","2164-9561"],"issn-type":[{"value":"2164-957X","type":"print"},{"value":"2164-9561","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7]]}}}