{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T14:38:09Z","timestamp":1777646289910,"version":"3.51.4"},"reference-count":31,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Glob Adv Health Med"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:p>Pediatric obsessive-compulsive disorder (OCD) is prevalent in 1% to 2% of the population. Emerging studies have correlated non-celiac gluten sensitivity with psychiatric conditions such as schizophrenia, depression, mania, and anxiety. This case study is the first reported case of OCD associated with non-celiac gluten sensitivity. The objectives of this case report are to (1) identify gluten sensitivity as a possible contributing factor to OCD in some patients; and (2) point out the possible benefit of an integrative medicine approach to the management of OCD in a patient with suboptimal benefit from a standard treatment regime. A 7-year-old male treated at a multi-physician integrative medicine practice in the United States had marked reduction of OCD symptoms and anxiety along with marked improvement of social behavior and school work after treatment consisting of gluten avoidance and other integrative medicine modalities. The patient's rapid response without side effects behooves the medical research community to further investigate the association of non-celiac gluten sensitivity and pediatric OCD.<\/jats:p>","DOI":"10.7453\/gahmj.2015.091","type":"journal-article","created":{"date-parts":[[2016,1,15]],"date-time":"2016-01-15T02:21:42Z","timestamp":1452824502000},"page":"117-121","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Integrative Medicine Approach to Pediatric Obsessive-Compulsive Disorder and Anxiety: a Case Report"],"prefix":"10.1177","volume":"5","author":[{"given":"Danielle Chung","family":"Couture","sequence":"first","affiliation":[{"name":"Perelman School of Medicine at the University of Pennsylvania, Philadelphia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myung Kyu","family":"Chung","sequence":"additional","affiliation":[{"name":"Cooper Medical School of Rowan University, Camden, New Jersey; Chung Institute of Integrative Medicine; Won Sook Chung Foundation, Moorestown, New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phillip","family":"Shinnick","sequence":"additional","affiliation":[{"name":"Research Institute of Global Physiology and Treatment, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Curzon","sequence":"additional","affiliation":[{"name":"Private Practice, Perkasie, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark J.","family":"Mcclure","sequence":"additional","affiliation":[{"name":"National Integrated Health Associates, Washington, DC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick J.","family":"Lariccia","sequence":"additional","affiliation":[{"name":"Adjunct Scholar Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia; Won Sook Chung Foundation, Moorestown, New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,1]]},"reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e32830f93d9"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.mp.4001823"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11126-011-9186-y"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-10-13"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2001.22123"},{"key":"e_1_3_1_7_2","article-title":"Gluten sensitivity presenting as a neuropsychiatric disorder.","author":"Genius S","unstructured":"GeniusS, LoboR. Gluten sensitivity presenting as a neuropsychiatric disorder. Gastroenterol Res Pract. http:\/\/dx.doi.org\/10.1155\/2014\/293206. Accessed December 16, 2015.","journal-title":"Gastroenterol Res Pract."},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu5103839"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13317-014-0064-0"},{"key":"e_1_3_1_10_2","unstructured":"KlinghardtD. Video demonstration: autonomic response testing versus classical kinesiology. http:\/\/www.klinghardtacademy.com\/Videos\/Autonomic-Response-Testing-vs-Classic-Kinesiology.html. Accessed December 16 2015."},{"issue":"4","key":"e_1_3_1_11_2","first-page":"182","article-title":"The use of autonomic response testing and the 5 phases paradigm to identify unresolved feelings in patients with mood disorder.","volume":"21","author":"Brobyn T","year":"2015","unstructured":"BrobynT, ChungMK. The use of autonomic response testing and the 5 phases paradigm to identify unresolved feelings in patients with mood disorder. Altern Complement Ther. 2015; 21(4): 182\u20138.","journal-title":"Altern Complement Ther."},{"key":"e_1_3_1_12_2","first-page":"184","article-title":"Neural therapy: an overlooked game changer for patients suffering chronic pain?","volume":"4","author":"Brobyn T","year":"2015","unstructured":"BrobynT, ChungMK, LaRicciaPJ. Neural therapy: an overlooked game changer for patients suffering chronic pain? J Pain Relief. 2015; 4: 184.","journal-title":"J Pain Relief."},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1047-9651(18)30180-3"},{"key":"e_1_3_1_14_2","volume-title":"Healing energies of heat and light.","author":"McGee CT","year":"2000","unstructured":"McGeeCT. Healing energies of heat and light. Coeur D'Alene, Idaho: Medipress; 2000."},{"key":"e_1_3_1_15_2","unstructured":"LaserRJ. RJ laser devices for controlled acupuncture\u2014what is required for diagnosis and therapy? http:\/\/www.rj-laser.com\/english\/pulse_controlled_acupuncture_laser_therapy.htm. Accessed December 17 2015."},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.3727\/036012986816359193"},{"issue":"2","key":"e_1_3_1_17_2","first-page":"195","article-title":"An introduction to the basic technique and theory of Omura's bi-digital O-ring test.","volume":"24","author":"Shinnick P.","year":"1996","unstructured":"ShinnickP. An introduction to the basic technique and theory of Omura's bi-digital O-ring test. Am J Acupuncture. 1996; 24(2\/3):195\u2013204.","journal-title":"Am J Acupuncture."},{"key":"e_1_3_1_18_2","unstructured":"Center for Research Strategies Inc. Evaluation of heavy metal levels in relation to ionic foot bath session with Ion Cleanse. 2008 http:\/\/www.ahrfoundation.net\/dlfiles\/study_results.pdf. Accessed December 17 2015."},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/258968"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtemb.2014.10.001"},{"key":"e_1_3_1_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtemb.2014.04.010"},{"key":"e_1_3_1_22_2","doi-asserted-by":"publisher","DOI":"10.1089\/acm.2012.0384"},{"key":"e_1_3_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbmt.2010.01.009"},{"key":"e_1_3_1_24_2","volume-title":"Pain management: a Ppactical guide for clinicians.","author":"Kirsch DL","year":"1998","unstructured":"KirschDL, LernerFN. Electromedicine the other side of physiology. In: WeinerR, editor. Pain management: a Ppactical guide for clinicians. 5th ed. Vol 2. Boca Raton, Florida: CRC Press LLC; 1998.","edition":"5"},{"issue":"3","key":"e_1_3_1_25_2","first-page":"243","article-title":"Practical clinical application of the Bi-Digital O-Ring Test in the diagnosis, treatment, and follow-up of tuberculosis and parasitic infection.","volume":"11","author":"Ong G","year":"1986","unstructured":"OngG, OmuraY. Practical clinical application of the Bi-Digital O-Ring Test in the diagnosis, treatment, and follow-up of tuberculosis and parasitic infection. Acupunct Electrother Res. 1986; 11(3-4): 243\u201350.","journal-title":"Acupunct Electrother Res."},{"issue":"3","key":"e_1_3_1_26_2","doi-asserted-by":"crossref","first-page":"201","DOI":"10.3727\/036012903815901570","article-title":"The importance of the Bi-Digital-O-Ring Test in the the treatment of multiple hepatic abscesses: a case history.","volume":"28","author":"Iwasa S","year":"2003","unstructured":"IwasaS, NevesIB, LopesAC. The importance of the Bi-Digital-O-Ring Test in the the treatment of multiple hepatic abscesses: a case history. Acupunct Electrother Res. 2003; 28(3-4): 201\u20136.","journal-title":"Acupunct Electrother Res."},{"key":"e_1_3_1_27_2","doi-asserted-by":"publisher","DOI":"10.3727\/036012914X14109544776051"},{"key":"e_1_3_1_28_2","doi-asserted-by":"publisher","DOI":"10.3727\/036012986816359085"},{"key":"e_1_3_1_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajp.2011.03.001"},{"key":"e_1_3_1_30_2","article-title":"ART, autonomic response testing.","author":"Klinghardt D","year":"1996","unstructured":"KlinghardtD, WilliamsL. ART, autonomic response testing. Self-published; 1996.","journal-title":"Self-published;"},{"key":"e_1_3_1_31_2","volume-title":"Applied kinesiology: synopsis.","author":"Walther D.","year":"2000","unstructured":"WaltherD. Applied kinesiology: synopsis. 2nd Ed. Pueblo, Colorado: Systems DC; 2000.","edition":"2"},{"key":"e_1_3_1_32_2","volume-title":"Whole person healing: the O-Ring imaging technique.","author":"Shinnick P","year":"2009","unstructured":"ShinnickP, BorgnaA. Whole person healing: the O-Ring imaging technique. Bloomington, IN: Author House; 2009."}],"container-title":["Global Advances in Health and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.7453\/gahmj.2015.091","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.7453\/gahmj.2015.091","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.7453\/gahmj.2015.091","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T06:34:50Z","timestamp":1777444490000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.7453\/gahmj.2015.091"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["10.7453\/gahmj.2015.091"],"URL":"https:\/\/doi.org\/10.7453\/gahmj.2015.091","relation":{},"ISSN":["2164-957X","2164-9561"],"issn-type":[{"value":"2164-957X","type":"print"},{"value":"2164-9561","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,1]]}}}