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However, there is limited data on the treatment options for aspergillosis-induced cerebral infarction especially surgical treatments such as superficial temporal artery (STA)-middle cerebral artery (MCA) bypass surgery.Herein, we present a case of cerebral infarction in a 59-year-old male with progressive right eye ptosis. Specifically, he had ipsilateral MCA stenosis originating from paranasal sinusitis due to invasive aspergillosis. After 3 months, the patient was readmitted due to worsening cerebral infarction and complete internal carotid artery (ICA) occlusion. Conservative treatment failed to improve cerebral perfusion, leading to gradual neurological decline. Consequently, STA-MCA bypass was performed to stabilise the patient. Postoperative imaging revealed a patent bypass graft and an enhanced cerebral perfusion. Although the patient experienced persistent left-sided hemiparesis, his overall neurological condition remained stable for 1 year, with a Glasgow Coma Scale score of 15.STA-MCA bypass should be considered a potential treatment option for patients with aspergillosis-induced vasculitis resulting in cerebral infarction secondary to total ICA occlusion.<\/jats:p>","DOI":"10.7461\/jcen.2025.e2024.06.003","type":"journal-article","created":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T19:35:26Z","timestamp":1744054526000},"page":"261-270","update-policy":"https:\/\/doi.org\/10.7461\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Superficial temporal artery-middle cerebral artery bypass for progressive cerebral infarction in invasive aspergillosis-induced total occlusion of internal carotid artery: A rare case and literature 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