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In this report, we describe the clinical and histopathologic features, the differential diagnoses, and successful treatment of this unusual disorder.<\/jats:p>","DOI":"10.7547\/14-009","type":"journal-article","created":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T20:12:31Z","timestamp":1443730351000},"page":"451-455","source":"Crossref","is-referenced-by-count":7,"title":["Kyrle Disease"],"prefix":"10.3390","volume":"105","author":[{"given":"Myron","family":"Bodman","sequence":"first","affiliation":[{"name":"Department of Podiatric Medicine, Kent State University College of Podiatric Medicine, Independence, OH."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duane","family":"Ehredt Jr","sequence":"additional","affiliation":[{"name":"Department of Podiatric Medicine and Surgery, St. Vincent's Charity Hospital, Cleveland, OH."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Barker","sequence":"additional","affiliation":[{"name":"Department of Podiatric Medicine and Surgery, University Hospitals Richmond Medical Center, Richmond Heights, OH."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amity","family":"Kirkland","sequence":"additional","affiliation":[{"name":"Department of Podiatric Medicine, Kent State University College of Podiatric Medicine, Independence, OH."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priyanka","family":"Mude","sequence":"additional","affiliation":[{"name":"Department of Podiatric Medicine, Kent State University College of Podiatric Medicine, Independence, OH."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","reference":[{"key":"i8750-7315-105-5-451-b01","series-title":"Arch Dermatol Syphilol","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1007\/BF01826081","article-title":"Hyperkeratosis follicularis et parafollicularis in cutem penetrans","volume":"123","author":"Kyrle\n              J:","year":"1916","unstructured":"Kyrle\n              J: \n          \n          Hyperkeratosis follicularis et parafollicularis in cutem penetrans. Arch Dermatol Syphilol123: 466, 1916.10.1007\/BF01826081"},{"key":"i8750-7315-105-5-451-b02","series-title":"J Am Acad Dermatol","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1016\/S0190-9622(84)80259-5","article-title":"The perforating disorders","volume":"10","author":"Patterson\n              JW,","year":"1984","unstructured":"Patterson\n              JW, \n            \n              Richmond\n              VA: \n          \n          The perforating disorders. J Am Acad Dermatol10: 561, 1984.10.1016\/S0190-9622(84)80259-56371074"},{"key":"i8750-7315-105-5-451-b03","series-title":"Br J Dermatol","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1111\/j.1365-2133.1996.tb03873.x","article-title":"Acquired perforating dermatosis in a British dialysis population","volume":"135","author":"Morton\n              C,","year":"1996","unstructured":"Morton\n              C, \n            \n              Henderson\n              I, \n            \n              Jones\n              M, \n            et al\n          : Acquired perforating dermatosis in a British dialysis population. Br J Dermatol135: 671, 1996.10.1111\/j.1365-2133.1996.tb03873.x"},{"key":"i8750-7315-105-5-451-b04","series-title":"Nephrol Dial Transplant","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1093\/ndt\/gfi204","article-title":"The role of micro-inflammation in the pathogenesis of uraemic pruritus in haemodialysis patients","volume":"21","author":"Kimmel\n              M,","year":"2006","unstructured":"Kimmel\n              M, \n            \n              Alscher\n              DM, \n            \n              Dunst\n              R, \n            et al\n          : The role of micro-inflammation in the pathogenesis of uraemic pruritus in haemodialysis patients. Nephrol Dial Transplant21: 749, 2006.10.1093\/ndt\/gfi20416249205"},{"key":"i8750-7315-105-5-451-b05","series-title":"J Infect","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1016\/j.jinf.2004.06.009","article-title":"Regression of skin lesions of Kyrle's disease with clindamycin: implications for an infectious component in the etiology of the disease","volume":"50","author":"Kasiakou\n              S,","year":"2005","unstructured":"Kasiakou\n              S, \n            \n              Peppas\n              G, \n            \n              Kapaskelis\n              A, \n            et al\n          : Regression of skin lesions of Kyrle's disease with clindamycin: implications for an infectious component in the etiology of the disease. J Infect50: 412, 2005.10.1016\/j.jinf.2004.06.00915907549"},{"key":"i8750-7315-105-5-451-b06","series-title":"Arch Dermatol","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1001\/archderm.1968.01610120023003","article-title":"Kyrle's disease: II. Histopathologic findings in five cases and review of the literature","volume":"97","author":"Constantine\n              VS,","year":"1968","unstructured":"Constantine\n              VS, \n            \n              Carter\n              VH: \n          \n          Kyrle's disease: II. Histopathologic findings in five cases and review of the literature. 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J Am Acad Dermatol16: 117, 1987.http:\/\/gateway.webofknowledge.com\/gateway\/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383369700008&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=b7bc2757938ac7a7a821505f8243d9f3380538010.1016\/S0190-9622(87)70011-5"},{"key":"i8750-7315-105-5-451-b08","series-title":"Am J Clin Dermatol","doi-asserted-by":"publisher","first-page":"47","DOI":"10.2165\/00128071-200203010-00005","article-title":"New and established topical corticosteroids in dermatology: clinical pharmacology and therapeutic use","volume":"3","author":"Brazzini\n              B,","year":"2002","unstructured":"Brazzini\n              B, \n            \n              Pimpinelli\n              N: \n          \n          New and established topical corticosteroids in dermatology: clinical pharmacology and therapeutic use. Am J Clin Dermatol3: 47, 2002.10.2165\/00128071-200203010-0000511817968"},{"key":"i8750-7315-105-5-451-b09","series-title":"J Am Acad Dermatol","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jaad.2005.01.010","article-title":"Adverse effects of topical glucocorticosteroids","volume":"54","author":"Hengge\n              U,","year":"2006","unstructured":"Hengge\n              U, \n            \n              Ruzicka\n              T, \n            \n              Schwatz\n              R, \n            et al\n          : Adverse effects of topical glucocorticosteroids. 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