{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T21:42:01Z","timestamp":1789594921214,"version":"build-2803163510"},"reference-count":8,"publisher":"MDPI AG","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:p>Nora's lesion, or bizarre parosteal osteochondromatous proliferation (BPOP), is a rare benign lesion that is made up of varying degrees of cartilage, bone, and spindle cells. Most notably, calcification of the cartilage or \u201cblue bone,\u201d is a feature of the disorder. The condition principally affects long tubular bones of the hands and feet, and is generally seen in patients in their second and third decades of life. We present a case of BPOP occurring in the second interspace with symptoms that would be consistent with a more common diagnosis of predislocation syndrome, or a second interspace neuroma. This case study may help the clinician in considering a more subtle cause of a splay deformity in the second interspace, and walk through the diagnostic and treatment course for BPOP.<\/jats:p>","DOI":"10.7547\/17-009","type":"journal-article","created":{"date-parts":[[2019,11,22]],"date-time":"2019-11-22T10:55:12Z","timestamp":1574420112000},"page":"463-466","source":"Crossref","is-referenced-by-count":5,"title":["Nora's Lesion: Bizarre Parosteal Osteochondromatous Proliferation Causing Splay Foot Deformity: A Case Report"],"prefix":"10.3390","volume":"109","author":[{"given":"Anthony J.","family":"Mollica","sequence":"first","affiliation":[{"name":"Saint John Hospital and Medical Center, Detroit, MI."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Getz","sequence":"additional","affiliation":[{"name":"Saint John Hospital and Medical Center, Detroit, MI."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chinenye","family":"Ezike","sequence":"additional","affiliation":[{"name":"Saint John Hospital and Medical Center, Detroit, MI."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blake","family":"Brannick","sequence":"additional","affiliation":[{"name":"Saint John Hospital and Medical Center, Detroit, MI."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert J.","family":"Mollica","sequence":"additional","affiliation":[{"name":"Podiatry BC, Vancouver, British Columbia, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","reference":[{"key":"i8750-7315-109-6-463-b01","series-title":"Am J Surg Pathol","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1097\/00000478-198304000-00003","article-title":"Bizarre parosteal osteochondromatous proliferations of the hands and feet","volume":"7","author":"Nora \n              FE,","year":"1983","unstructured":"Nora \n              FE, \n            \n            \n              Dahlin \n              DC, \n            \n            \n              Beabout \n              JW: \n            \n          \n          Bizarre parosteal osteochondromatous proliferations of the hands and feet. Am J Surg Pathol7: 245, 1983.683783410.1097\/00000478-198304000-00003"},{"key":"i8750-7315-109-6-463-b02","series-title":"Case Rep Med","doi-asserted-by":"publisher","first-page":"453560","DOI":"10.1155\/2012\/453560","article-title":"Bizarre parosteal osteochondromatous proliferation (Nora's lesion) of the hand: a report of two atypical cases","volume":"2012","author":"Barrera-Ochoa \n              S,","year":"2012","unstructured":"Barrera-Ochoa \n              S, \n            \n            \n              Lluch \n              A, \n            \n            \n              Gargallo-Margarit \n              A, \n            \n            et al: \n          Bizarre parosteal osteochondromatous proliferation (Nora's lesion) of the hand: a report of two atypical cases. Case Rep Med2012: 453560, 2012.2332627410.1155\/2012\/453560"},{"key":"i8750-7315-109-6-463-b03","series-title":"JAPMA","first-page":"80","article-title":"Bizarre parosteal osteochondromatous proliferation: a novel case report of recurrence in the toe","volume":"105","author":"Holmes \n              C,","year":"2015","unstructured":"Holmes \n              C, \n            \n            \n              Choksi \n              P, \n            \n            \n              Wrobel \n              JS: \n            \n          \n          Bizarre parosteal osteochondromatous proliferation: a novel case report of recurrence in the toe. JAPMA105: 80, 2015."},{"key":"i8750-7315-109-6-463-b04","series-title":"Hand (N Y)","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1007\/s11552-009-9217-4","article-title":"Benign parosteal osteochondromatous proliferation of the hand originally diagnosed as osteochondroma: a report of two cases and review","volume":"5","author":"Chamberlain \n              AM,","year":"2012","unstructured":"Chamberlain \n              AM, \n            \n            \n              Anderson \n              KL, \n            \n            \n              Hoch \n              B, \n            \n            et al: \n          Benign parosteal osteochondromatous proliferation of the hand originally diagnosed as osteochondroma: a report of two cases and review. Hand (N Y)5: 106, 2012.10.1007\/s11552-009-9217-4"},{"key":"i8750-7315-109-6-463-b05","series-title":"J Hand Surg","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1016\/j.jhsa.2007.04.004","article-title":"Bizarre parosteal osteochondromatous proliferation and periosteal chondroma: a comparative report and review of literature","volume":"32","author":"Flint \n              JH,","year":"2007","unstructured":"Flint \n              JH, \n            \n            \n              Mckay \n              PL: \n            \n          \n          Bizarre parosteal osteochondromatous proliferation and periosteal chondroma: a comparative report and review of literature. J Hand Surg32: 893, 2007.10.1016\/j.jhsa.2007.04.004http:\/\/gateway.webofknowledge.com\/gateway\/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000248195000021&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=b7bc2757938ac7a7a821505f8243d9f3"},{"key":"i8750-7315-109-6-463-b06","series-title":"Am J Surg Pathol","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1097\/00000478-199307000-00006","article-title":"Bizarre parosteal osteochondromatous proliferation of bone (Nora's lesion)","volume":"17","author":"Meneses \n              MF,","year":"1993","unstructured":"Meneses \n              MF, \n            \n            \n              Unni \n              K, \n            \n            \n              Swee \n              RG: \n            \n          \n          Bizarre parosteal osteochondromatous proliferation of bone (Nora's lesion). Am J Surg Pathol17: 691, 1993.831760910.1097\/00000478-199307000-00006"},{"key":"i8750-7315-109-6-463-b07","series-title":"Hum Pathol","doi-asserted-by":"publisher","first-page":"1205","DOI":"10.1053\/hupa.2002.130103","article-title":"Bizarre parosteal osteochondromatous proliferation (Nora's lesion): a retrospective study of 12 cases, 2 arising in long bones","volume":"333","author":"Abramovici \n              L,","year":"2002","unstructured":"Abramovici \n              L, \n            \n            \n              Steiner \n              GC: \n            \n          \n          Bizarre parosteal osteochondromatous proliferation (Nora's lesion): a retrospective study of 12 cases, 2 arising in long bones. Hum Pathol333: 1205, 2002.10.1053\/hupa.2002.130103"},{"key":"i8750-7315-109-6-463-b08","series-title":"Virchows Arch","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1007\/s00428-005-1266-7","article-title":"Bizarre parosteal osteochondromatous proliferation with a t(1;17) translocation","volume":"447","author":"Endo \n              M,","year":"2005","unstructured":"Endo \n              M, \n            \n            \n              Hasegawa \n              T, \n            \n            \n              Tashiro \n              T, \n            \n            et al: \n          Bizarre parosteal osteochondromatous proliferation with a t(1;17) translocation. Virchows Arch447: 99, 2005.10.1007\/s00428-005-1266-7"}],"container-title":["Journal of the American Podiatric Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/japmaonline.org\/view\/journals\/apms\/109\/6\/17-009.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/japma\/article-pdf\/109\/6\/463\/2458335\/17-009.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/japmaonline.org\/downloadpdf\/journals\/apms\/109\/6\/17-009.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/japmaonline.org\/downloadpdf\/journals\/apms\/109\/6\/17-009.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T10:17:47Z","timestamp":1783505867000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1930-8264\/109\/6\/463"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":8,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.7547\/17-009","relation":{},"ISSN":["8750-7315","1930-8264"],"issn-type":[{"value":"8750-7315","type":"print"},{"value":"1930-8264","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11]]}}}