{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T11:14:16Z","timestamp":1783509256330,"version":"3.55.0"},"reference-count":36,"publisher":"MDPI AG","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,1,1]]},"abstract":"<jats:p>Intraosseous lipomas are rare benign bone neoplasms with an incidence of less than 0.1%; origin in the calcaneus has been reported in only a few patients. First-line treatment remains conservative, but several surgical techniques have also been described. We describe a 44-year-old woman with increasing pain in her left heel for a year and a half, who noticed swelling on the lateral side of the calcaneus. The patient underwent radiography, magnetic resonance imaging, and computed tomography of her left foot, which was suspicious for an intraosseous lipoma with a threatening calcaneal fracture. We performed a surgical procedure, curettage of the tumor, spongioplastics (by autologous bone transplant and \u03b2-tricalcium phosphate), and internal stabilization with a calcaneal plate considering the goal of immediate postoperative weightbearing. Histologic examination confirmed an intraosseous lipoma of the calcaneus. The patient's pain was relieved immediately after surgery. Internal stabilization of the calcaneus allowed the patient to immediately fully weightbear and to return to usual daily activities. Although a benign bone tumor, intraosseous lipoma can cause many complications, such as persistent pain, decreased function, or even pathologic fracture as a result of calcaneal bone weakening. Choosing an appropriate treatment is still controversial. Conservative treatment is the first option, but for patients with severe problems and threatening fracture, surgery is necessary. Internal fixation for stabilization enables immediate postoperative weightbearing and shortens recovery time.<\/jats:p>","DOI":"10.7547\/17-077","type":"journal-article","created":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T13:03:28Z","timestamp":1554815008000},"page":"75-79","source":"Crossref","is-referenced-by-count":5,"title":["Threatening Fracture of Intraosseous Lipoma Treated by Internal Fixation"],"prefix":"10.3390","volume":"109","author":[{"given":"Igor","family":"Frange\u017e","sequence":"first","affiliation":[{"name":"Department of Traumatology, Surgical Clinic, Clinical Center Ljubljana, Ljubljana, Slovenia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tea","family":"Nizi\u010d-Kos","sequence":"additional","affiliation":[{"name":"Department of Traumatology, Surgical Clinic, Clinical Center Ljubljana, Ljubljana, Slovenia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matej","family":"Cimerman","sequence":"additional","affiliation":[{"name":"Department of Traumatology, Surgical Clinic, Clinical Center Ljubljana, Ljubljana, Slovenia."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,1,1]]},"reference":[{"key":"ref101","first-page":"51","article-title":"The \u201ccockade\u201d image: a diagnostic sign of calcaneum intraosseous lipoma","volume":"11","author":"Bruni","year":"1986","journal-title":"Rays"},{"key":"ref171","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1016\/j.ijom.2007.07.014","article-title":"Guided bone regeneration at dehiscence-type defects using biphasic hydroxyapatite + beta tricalcium phosphate (Bone Ceramic\u00ae) or a collagen-coated natural bone mineral (BioOss Collagen\u00ae): an immunohistochemical study in dogs","volume":"36","author":"Schwarz","year":"2007","journal-title":"Int J Oral Maxillofac Surg"},{"key":"ref271","first-page":"1","article-title":"Calcaneal intraosseous lipoma treated with external fixation: case report and review of the literature","volume":"5","author":"Losito","year":"2012","journal-title":"Foot Ankle Online J"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"526","DOI":"10.4055\/jkoa.2003.38.5.526","article-title":"Intraosseous lipoma","volume":"38","author":"Shin","year":"2003","journal-title":"J Korean Orthop Assoc"},{"key":"ref211","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1097\/00003086-198806000-00035","article-title":"Intraosseous lipomas: a clinicopathologic study of 66 cases","volume":"231","author":"Milgram","year":"1988","journal-title":"Clin Orthop Relat Res"},{"key":"ref111","doi-asserted-by":"crossref","first-page":"673","DOI":"10.2214\/ajr.175.3.1750673","article-title":"Radiologic-pathologic correlation of intraosseous lipomas","volume":"175","author":"Propeck","year":"2000","journal-title":"AJR Am J Roentgenol"},{"key":"ref81","first-page":"315","article-title":"Pseudo-cysts, lipomas, infarcts and simple cysts of the calcaneus: are there different or related lesions?","volume":"90","author":"Diard","year":"2007","journal-title":"JBR-BTR"},{"key":"ref221","doi-asserted-by":"crossref","first-page":"526","DOI":"10.4055\/jkoa.2003.38.5.526","article-title":"Intraosseous lipoma","volume":"38","author":"Shin","year":"2003","journal-title":"J Korean Orthop Assoc"},{"key":"ref311","first-page":"33","article-title":"Surgery is not always necessary in intraosseous lipoma","volume":"12","author":"Begatur","year":"2010","journal-title":"Orthopedics"},{"key":"ref301","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1007\/BF00193088","article-title":"Malignant transformation in bone lipomas","volume":"19","author":"Milgram","year":"1990","journal-title":"Skeletal Radiol"},{"key":"ref21","article-title":"\u201cTumor of Fat,\u201d","author":"Mirra","year":"1989","journal-title":"Bone Tumors"},{"key":"ref71","first-page":"374","article-title":"Intraosseous lipoma: retrospective analysis of 29 patients","volume":"28","author":"Radl","year":"2004","journal-title":"Int Othop"},{"key":"ref191","first-page":"349","article-title":"\u201cLipoma and Liposarcoma,\u201d","author":"Krishnan Unni","year":"1996","journal-title":"Dahlin's Bone Tumors: General Aspects and Data on 11.087 Cases"},{"key":"ref251","first-page":"374","article-title":"Intraosseous lipoma: retrospective analysis of 29 patients","volume":"28","author":"Radl","year":"2004","journal-title":"Int Othop"},{"key":"ref61","first-page":"603","article-title":"Osseous lipoma: eleven new cases and review of the literature","volume":"72","author":"Kapakaya","year":"2006","journal-title":"Acta Orthop Belg"},{"key":"ref201","article-title":"\u201cTumor of Fat,\u201d","author":"Mirra","year":"1989","journal-title":"Bone Tumors"},{"key":"ref231","first-page":"1","article-title":"A rare case of aneurysmal bone cyst of the calcaneum","volume":"4","author":"Soraganvi","year":"2011","journal-title":"Foot Ankle Online J"},{"key":"ref181","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.anndiagpath.2006.09.006","article-title":"Intraosseous lipoma: a clinical, radiologic, and pathologic study of 5 cases","volume":"11","author":"Eyzaguirre","year":"2007","journal-title":"Ann Diagn Pathol"},{"key":"ref291","doi-asserted-by":"crossref","first-page":"673","DOI":"10.2214\/ajr.175.3.1750673","article-title":"Radiologic-pathologic correlation of intraosseous lipomas","volume":"175","author":"Propeck","year":"2000","journal-title":"AJR Am J Roentgenol"},{"key":"ref51","first-page":"1","article-title":"A rare case of aneurysmal bone cyst of the calcaneum","volume":"4","author":"Soraganvi","year":"2011","journal-title":"Foot Ankle Online J"},{"key":"ref331","first-page":"4311","article-title":"Successful treatment of bilateral calcaneal intraosseous lipomas using endoscopically assisted tumor resection","volume":"27","author":"Futani","year":"2007","journal-title":"Anticancer Res"},{"key":"ref141","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.foot.2009.01.005","article-title":"Surgical treatment for calcaneal intraosseous lipomas","volume":"19","author":"Ulucay","year":"2009","journal-title":"Foot (Edinb)"},{"key":"ref241","first-page":"603","article-title":"Osseous lipoma: eleven new cases and review of the literature","volume":"72","author":"Kapakaya","year":"2006","journal-title":"Acta Orthop Belg"},{"key":"ref121","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1007\/BF00193088","article-title":"Malignant transformation in bone lipomas","volume":"19","author":"Milgram","year":"1990","journal-title":"Skeletal Radiol"},{"key":"ref01","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.anndiagpath.2006.09.006","article-title":"Intraosseous lipoma: a clinical, radiologic, and pathologic study of 5 cases","volume":"11","author":"Eyzaguirre","year":"2007","journal-title":"Ann Diagn Pathol"},{"key":"ref261","first-page":"315","article-title":"Pseudo-cysts, lipomas, infarcts and simple cysts of the calcaneus: are there different or related lesions?","volume":"90","author":"Diard","year":"2007","journal-title":"JBR-BTR"},{"key":"ref351","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1016\/j.ijom.2007.07.014","article-title":"Guided bone regeneration at dehiscence-type defects using biphasic hydroxyapatite + beta tricalcium phosphate (Bone Ceramic\u00ae) or a collagen-coated natural bone mineral (BioOss Collagen\u00ae): an immunohistochemical study in dogs","volume":"36","author":"Schwarz","year":"2007","journal-title":"Int J Oral Maxillofac Surg"},{"key":"ref91","first-page":"1","article-title":"Calcaneal intraosseous lipoma treated with external fixation: case report and review of the literature","volume":"5","author":"Losito","year":"2012","journal-title":"Foot Ankle Online J"},{"key":"ref131","first-page":"33","article-title":"Surgery is not always necessary in intraosseous lipoma","volume":"12","author":"Begatur","year":"2010","journal-title":"Orthopedics"},{"key":"ref11","first-page":"349","article-title":"\u201cLipoma and Liposarcoma,\u201d","author":"Krishnan Unni","year":"1996","journal-title":"Dahlin's Bone Tumors: General Aspects and Data on 11.087 Cases"},{"key":"ref161","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1148\/radiology.167.1.3347718","article-title":"Intraosseous lipomas: radiologic and pathologic manifestation","volume":"167","author":"Milgram","year":"1988","journal-title":"Radiology"},{"key":"ref281","first-page":"51","article-title":"The \u201ccockade\u201d image: a diagnostic sign of calcaneum intraosseous lipoma","volume":"11","author":"Bruni","year":"1986","journal-title":"Rays"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1097\/00003086-198806000-00035","article-title":"Intraosseous lipomas: a clinicopathologic study of 66 cases","volume":"231","author":"Milgram","year":"1988","journal-title":"Clin Orthop Relat Res"},{"key":"ref151","first-page":"4311","article-title":"Successful treatment of bilateral calcaneal intraosseous lipomas using endoscopically assisted tumor resection","volume":"27","author":"Futani","year":"2007","journal-title":"Anticancer Res"},{"key":"ref341","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1148\/radiology.167.1.3347718","article-title":"Intraosseous lipomas: radiologic and pathologic manifestation","volume":"167","author":"Milgram","year":"1988","journal-title":"Radiology"},{"key":"ref321","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.foot.2009.01.005","article-title":"Surgical treatment for calcaneal intraosseous lipomas","volume":"19","author":"Ulucay","year":"2009","journal-title":"Foot (Edinb)"}],"container-title":["Journal of the American Podiatric Medical Association"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/meridian.allenpress.com\/japma\/article-pdf\/109\/1\/75\/2459106\/17-077.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/meridian.allenpress.com\/japma\/article-pdf\/109\/1\/75\/2459106\/17-077.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T10:17:36Z","timestamp":1783505856000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1930-8264\/109\/1\/75"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,1]]},"references-count":36,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019,1,1]]},"published-print":{"date-parts":[[2019,1,1]]}},"URL":"https:\/\/doi.org\/10.7547\/17-077","relation":{},"ISSN":["8750-7315","1930-8264"],"issn-type":[{"value":"8750-7315","type":"print"},{"value":"1930-8264","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,1]]}}}