{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T11:14:23Z","timestamp":1783509263621,"version":"3.55.0"},"reference-count":6,"publisher":"MDPI AG","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,7]]},"abstract":"The purpose of this case report is to show the clinical presentation of a rare genetic disorder, called fibrodysplasia ossificans progressiva, on the development of the foot in a newborn. Shortened great toes and malformations of the first metatarsals are present in all affected individuals at birth. Irreversible heterotopic endochondral ossification of soft tissues occurs in the first decade of life, often resulting in permanent immobility by the third decade of life. Trauma caused by surgical excision of nodules, dental procedures, or injections can further exacerbate this condition. Early diagnosis is imperative for these patients to prevent irreversible damage that may result from unnecessary invasive interventions. This case report presents a boy aged 2 years 3 months who was born with bilateral bunion deformity. The goal is to raise awareness of this disorder in the podiatric community, especially for those who work with pediatric patients.<\/jats:p>","DOI":"10.7547\/18-021","type":"journal-article","created":{"date-parts":[[2019,7,18]],"date-time":"2019-07-18T14:01:38Z","timestamp":1563458498000},"page":"317-321","source":"Crossref","is-referenced-by-count":0,"title":["Fibrodysplasia Ossificans Progressiva and Its Implications in Podiatric Medicine: A Case Report"],"prefix":"10.3390","volume":"109","author":[{"given":"Nicholas","family":"Bolognini","sequence":"first","affiliation":[{"name":"Palo Alto Foundation Medical Group, Mountain View, CA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil Navendu","family":"Trivedi","sequence":"additional","affiliation":[{"name":"California School of Podiatric Medicine, Oakland, CA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew S.","family":"Au","sequence":"additional","affiliation":[{"name":"California School of Podiatric Medicine, Oakland, CA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nishit","family":"Vora","sequence":"additional","affiliation":[{"name":"California School of Podiatric Medicine, Oakland, CA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","reference":[{"key":"i8750-7315-109-4-317-b01","series-title":"Connective Tissue and Its Heritable Disorders: Molecular, Genetic, and Medical Aspects, Vol 2","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1002\/0471221929.ch21","article-title":"\u201cFibrodysplasia ossificans progressiva (FOP), \u201d","author":"Kaplan \n FS,","year":"2002","unstructured":"Kaplan \n FS, \n \n \n Shore \n EM, \n \n \n Connor \n JM: \n \n \n \u201cFibrodysplasia ossificans progressiva (FOP), \u201d\n in\n Connective Tissue and Its Heritable Disorders: Molecular, Genetic, and Medical Aspects, Vol 2, edited byPMRoyce, BSteinmann, p827, Wiley-Liss, Inc, New York, 2002.10.1002\/0471221929.ch21"},{"key":"i8750-7315-109-4-317-b02","series-title":"Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Vol 8","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1002\/9781118453926.ch98","article-title":"\u201cFibrodysplasia (myositis) ossificans progressive,\u201d","author":"Kaplan, \n FS,","year":"2013","unstructured":"Kaplan, \n FS, \n \n \n Pignolo \n RJ, \n \n \n Shore \n EM: \n \n \n \u201cFibrodysplasia (myositis) ossificans progressive,\u201d\n in\n Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Vol 8, p815, Wiley-Blackwell, John Wiley & Sons, Inc, Hoboken, 2013.10.1002\/9781118453926.ch98"},{"key":"i8750-7315-109-4-317-b03","series-title":"Dis Models Mech","doi-asserted-by":"publisher","first-page":"756","DOI":"10.1242\/dmm.010280","article-title":"Fibrodysplasia ossificans progressiva: mechanisms and models of skeletal metamorphosis","volume":"5","author":"Kaplan \n FS,","year":"2012","unstructured":"Kaplan \n FS, \n \n \n Chakkalakal \n SA, \n \n \n Shore \n EM: \n \n \n Fibrodysplasia ossificans progressiva: mechanisms and models of skeletal metamorphosis. Dis Models Mech5: 756, 2012.10.1242\/dmm.010280http:\/\/gateway.webofknowledge.com\/gateway\/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000311859700008&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=b7bc2757938ac7a7a821505f8243d9f3"},{"key":"i8750-7315-109-4-317-b04","series-title":"Johns Hopkins Med J","first-page":"73","article-title":"The hand and foot malformations in fibrodysplasia ossificans progressiva","volume":"147","author":"Schroeder \n HW\n Jr,","year":"1980","unstructured":"Schroeder \n HW\n Jr, \n \n \n Zasloff \n M: \n \n \n The hand and foot malformations in fibrodysplasia ossificans progressiva. Johns Hopkins Med J147: 73, 1980.7412069"},{"key":"i8750-7315-109-4-317-b05","series-title":"J Bone Joint Surg Br","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1302\/0301-620X.64B1.7068725","article-title":"Fibrodysplasia ossificans progressiva: the clinical features and natural history of 34 patients","volume":"64","author":"Connor \n JM,","year":"1982","unstructured":"Connor \n JM, \n \n \n Evans \n DAP: \n \n \n Fibrodysplasia ossificans progressiva: the clinical features and natural history of 34 patients. 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