{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T11:14:25Z","timestamp":1783509265821,"version":"3.55.0"},"reference-count":12,"publisher":"MDPI AG","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:p>Tenosynovial giant cell tumor, also known as giant cell tumor of the tendon sheath (GCT-TS), is a solitary, nodular, firm, benign, soft-tissue tumor that arises from the synovial lining of a tendon. The etiology is unknown. It is a rare soft-tissue tumor, with an overall incidence of one in 50,000 individuals, and usually affects people aged between 30 and 50 years. Magnetic resonance imaging tends to be the imaging modality of choice, used for surgical preparation. Widely accepted treatment involves local excision with or without radiotherapy. The author presents a case study involving a patient with an abnormally large, longstanding GCT-TS, diagnosed with clinical examination and imaging modalities, surgically excised, and further confirmed by pathology reports. Topic of discussion includes a review of GCT-TS.<\/jats:p>","DOI":"10.7547\/18-038","type":"journal-article","created":{"date-parts":[[2021,6,18]],"date-time":"2021-06-18T17:01:00Z","timestamp":1624035660000},"source":"Crossref","is-referenced-by-count":2,"title":["Atypical Tenosynovial Giant Cell Tumor of the Foot and Ankle: A Case Report"],"prefix":"10.3390","volume":"111","author":[{"given":"Peter","family":"Awad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","reference":[{"key":"i8750-7315-111-3-Article_19-b01","series-title":"OA Orthopaedics","first-page":"11","article-title":"Giant-cell tumour of the tendon sheath: a review","volume":"2","author":"Rukavina","year":"2014","unstructured":"Rukavina\n              I\n            \n            \n              \u0106aleta\n              D:\n            \n          \n          Giant-cell tumour of the tendon sheath: a review.\n\t\t\t\t\tOA Orthopaedics2: 11,\n\t\t\t\t\t2014."},{"key":"i8750-7315-111-3-Article_19-b02","series-title":"Diagn Cytopathol","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1002\/dc.10319","article-title":"Fine-needle aspiration cytology of giant cell tumor of tendon sheath","volume":"29","author":"Venkateswaran","year":"2003","unstructured":"Venkateswaran\n              KI\n            \n            \n              Kusum\n              K\n            \n            \n              Kusum\n              V:\n            \n          \n          Fine-needle aspiration cytology of giant cell tumor of tendon sheath.\n\t\t\t\t\tDiagn Cytopathol29: 105,\n\t\t\t\t\t2003.\n\t\t\t\t1288905110.1002\/dc.10319"},{"key":"i8750-7315-111-3-Article_19-b03","series-title":"J Surg Oncol","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1002\/jso.23220","article-title":"A multidisciplinary approach to giant cell tumors of tendon sheath and synovium: a critical appraisal of literature and treatment proposal","volume":"107","author":"van der Heiden","year":"2013","unstructured":"van der Heiden\n              L\n            \n            \n              Gibbons\n              CL\n            \n            \n              Hassan\n              AB\n            \n            :\n          \n          A multidisciplinary approach to giant cell tumors of tendon sheath and synovium: a critical appraisal of literature and treatment proposal.\n\t\t\t\t\tJ Surg Oncol107: 433,\n\t\t\t\t\t2013.\n\t\t\t\t10.1002\/jso.2322022806927"},{"key":"i8750-7315-111-3-Article_19-b04","series-title":"SA Orthop J","first-page":"39","article-title":"Giant cell tumour of the tendon sheath (GCT-TS) in the foot: a case report","volume":"13:","author":"Mayet","year":"2014","unstructured":"Mayet\n              Z\n            \n            \n              Noble\n              T\n            \n            \n              Magobotha\n              SKM:\n            \n          \n          Giant cell tumour of the tendon sheath (GCT-TS) in the foot: a case report.\n\t\t\t\t\tSA Orthop J13:39,\n\t\t\t\t\t2014.\n\t\t\t\t\tAvailable at: http:\/\/www.scielo.org.za\/scielo.php?script=sci_arttext&pid=S1681-150X2014000100007&lng=en&nrm=iso. Accessed February 21,2018."},{"key":"i8750-7315-111-3-Article_19-b05","series-title":"Br J Surg","first-page":"257","article-title":"Benign giant-cell synovioma. An investigation of 85 cases","volume":"38","author":"Wright","year":"1951","unstructured":"Wright\n              CJE:\n            \n          \n          Benign giant-cell synovioma. An investigation of 85 cases.\n\t\t\t\t\tBr J Surg38: 257,\n\t\t\t\t\t1951.\n\t\t\t\t14812103"},{"key":"i8750-7315-111-3-Article_19-b06","series-title":"J Ultrasound Med","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.7863\/jum.2007.26.10.1333","article-title":"The value of sonography in diagnosing giant cell tumors of the tendon sheath","volume":"26","author":"Tan","year":"2007","unstructured":"Tan\n              YWJ\n            \n            \n              Luo\n              Y:\n            \n          \n          The value of sonography in diagnosing giant cell tumors of the tendon sheath.\n\t\t\t\t\tJ Ultrasound Med26: 1333,\n\t\t\t\t\t2007.\n\t\t\t\thttp:\/\/gateway.webofknowledge.com\/gateway\/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000250244400006&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=b7bc2757938ac7a7a821505f8243d9f31790113610.7863\/jum.2007.26.10.1333"},{"key":"i8750-7315-111-3-Article_19-b07","series-title":"JAPMA","first-page":"231","article-title":"Diffuse type tenosynovial giant cell tumor of the ankle","volume":"83","author":"Horvath","year":"1993","unstructured":"Horvath\n              RR\n            \n            \n              Bostanche\n              J\n            \n            \n              Altman\n              MI:\n            \n          \n          Diffuse type tenosynovial giant cell tumor of the ankle.\n\t\t\t\t\tJAPMA83: 231,\n\t\t\t\t\t1993."},{"key":"i8750-7315-111-3-Article_19-b08","series-title":"J Foot Ankle Surg","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1053\/j.jfas.2004.09.002","article-title":"Pigmented villonodular synovitis of the foot and ankle: a 12 year experience from a tertiary orthopedic oncology unit","volume":"43","author":"Bisbinas","year":"2004","unstructured":"Bisbinas\n              I\n            \n            \n              De Silva\n              U\n            \n            \n              Grimer\n              RJ:\n            \n          \n          Pigmented villonodular synovitis of the foot and ankle: a 12 year experience from a tertiary orthopedic oncology unit.\n\t\t\t\t\tJ Foot Ankle Surg43: 407,\n\t\t\t\t\t2004.\n\t\t\t\t1560505410.1053\/j.jfas.2004.09.002"},{"key":"i8750-7315-111-3-Article_19-b09","series-title":"JAPMA","first-page":"557","article-title":"Giant cell tumor of the plantar fascia: a case report","volume":"77","author":"Frankel","year":"1987","unstructured":"Frankel\n              SL\n            \n            \n              Chioros\n              PG\n            \n            \n              Sidlow\n              CJ:\n            \n          \n          Giant cell tumor of the plantar fascia: a case report.\n\t\t\t\t\tJAPMA77: 557,\n\t\t\t\t\t1987."},{"key":"i8750-7315-111-3-Article_19-b10","series-title":"JAPMA","first-page":"270","article-title":"Giant cell tumor of tendon sheath in the toe","volume":"90","author":"Lo","year":"2000","unstructured":"Lo\n              EP\n            \n            \n              Ketterer\n              D:\n            \n          \n          Giant cell tumor of tendon sheath in the toe.\n\t\t\t\t\tJAPMA90: 270,\n\t\t\t\t\t2000."},{"key":"i8750-7315-111-3-Article_19-b11","series-title":"JAPMA","first-page":"368","article-title":"Pedal giant cell tumor of tendon sheath","volume":"89","author":"Paez","year":"1999","unstructured":"Paez\n              H\n            \n            \n              Vuletin\n              JC\n            \n            \n              Soave\n              RL\n            \n            :\n          \n          Pedal giant cell tumor of tendon sheath.\n\t\t\t\t\tJAPMA89: 368,\n\t\t\t\t\t1999."},{"key":"i8750-7315-111-3-Article_19-b12","series-title":"JAPMA","first-page":"249","article-title":"Giant cell tumor of the tendon sheath around the foot and ankle","volume":"105","author":"Vargaonkar","year":"2015","unstructured":"Vargaonkar\n              G\n            \n            \n              Singh\n              V\n            \n            \n              Arora\n              S\n            \n            :\n          \n          Giant cell tumor of the tendon sheath around the foot and ankle.\n\t\t\t\t\tJAPMA105: 249,\n\t\t\t\t\t2015."}],"container-title":["Journal of the American Podiatric Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/japmaonline.org\/view\/journals\/apms\/111\/3\/i8750-7315-111-3-article_19.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/japma\/article-pdf\/doi\/10.7547\/18-038\/2847469\/i8750-7315-111-3-article_19.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/japmaonline.org\/downloadpdf\/journals\/apms\/111\/3\/i8750-7315-111-3-article_19.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/japmaonline.org\/downloadpdf\/journals\/apms\/111\/3\/i8750-7315-111-3-article_19.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T10:18:15Z","timestamp":1783505895000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1930-8264\/111\/3\/18038"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":12,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.7547\/18-038","relation":{},"ISSN":["8750-7315"],"issn-type":[{"value":"8750-7315","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5]]}}}