{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T11:14:25Z","timestamp":1783509265808,"version":"3.55.0"},"reference-count":41,"publisher":"MDPI AG","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec id=\"st1\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Desmoid-type fibromatosis (DF) is an aggressive (myo)fibroblastic neoplasm with an infiltrative growth pattern and a tendency for local recurrence. It is rarely seen at the foot. The aim of this retrospective study was to analyze clinical presentation, therapy, and outcomes in a consecutive series of four patients with DF at the foot.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st2\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From 1994 to 2014, four patients had been surgically treated. The resection margin was marginal or even intralesional in all. One patient already had local recurrence at first presentation. The end point was either local recurrence or progression of residual disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st3\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The mean patient age was 27 years. In one patient, marginal excision healed the disease. In another patient, local recurrence after marginal resection necessitated distal phalanx amputation. Two other patients showed stable disease after either adjuvant radiotherapy or treatment with nonsteroidal anti-inflammatory drugs and tamoxifen.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st4\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>If surgery is necessary, operative margins are less important than keeping function for the patient. Radiotherapy might be an option to avoid major amputation. The role of adjuvant radiotherapy is controversially discussed. A watchful wait-and-see policy seems to be justified by the published data but may be difficult for DF at the foot.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.7547\/19-042","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T13:59:57Z","timestamp":1607608797000},"source":"Crossref","is-referenced-by-count":1,"title":["Desmoid Tumors of the Foot: A Retrospective Study of Four Patients"],"prefix":"10.3390","volume":"110","author":[{"given":"Hans R.","family":"D\u00fcrr","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Wirth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Baur-Melnyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Kn\u00f6sel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Falk","family":"Roeder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volkmar","family":"Jansson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Klein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","reference":[{"key":"i8750-7315-110-6-Article_14-b01","series-title":"WHO Classification of Tumours of Soft Tissue and Bone, Vol 4","article-title":"\u201cDesmoid-Type Fibromatosis,\u201c","author":"Goldblum","year":"2013","unstructured":"Goldblum\n              JR\n            \n            \n              Fletcher\n              JA:\n            \n          \n          \u201cDesmoid-Type Fibromatosis,\u201c\n           in\n          \n            WHO Classification of Tumours of Soft Tissue and Bone, Vol 4\n          , ed by\n          \n            \n              Fletcher\n              CDM\n            \n            \n              Hogendoorn\n              PCW\n            \n            \n              Mertens\n              F\n            \n          \n          et al, p 72, International Agency for Research on Cancer, Lyon,\n          2013."},{"key":"i8750-7315-110-6-Article_14-b02","series-title":"Clinical Reports of the Surgical Practice of Glasgow Royal Infirmary","first-page":"63","author":"MacFarlane","year":"1832","unstructured":"MacFarlane\n              J\n            \n          :\n\t\t\t\t\tClinical Reports of the Surgical Practice of Glasgow Royal Infirmary, p63,\n\t\t\t\t\tRobertson,\n\t\t\t\t\tGlasgow,\n\t\t\t\t\t1832."},{"key":"i8750-7315-110-6-Article_14-b03","series-title":"\u00dcber den feinern Bau und die Formen der krankhaften Geschw\u00fclste, Volume Erste Lieferung, p 60, G. Reimer, Berlin,","article-title":"\u201cVon der sehnigen Fasergeschwulst, Tumor fibrosus s. Desmoides,\u201c","author":"M\u00fcller","year":"1838","unstructured":"M\u00fcller\n              J:\n            \n          \n          \u201cVon der sehnigen Fasergeschwulst, Tumor fibrosus s. Desmoides,\u201c\n           in\n          \n            \u00dcber den feinern Bau und die Formen der krankhaften Geschw\u00fclste, Volume Erste Lieferung, p 60, G. Reimer, Berlin,\n          1838."},{"key":"i8750-7315-110-6-Article_14-b04","series-title":"Am J Clin Pathol","first-page":"66","article-title":"The desmoid tumor: I. Incidence, sex-, age- and anatomical distribution in the Finnish population","volume":"77","author":"Reitamo","year":"1982","unstructured":"Reitamo\n              JJ\n            \n            \n              Hayry\n              P\n            \n            \n              Nykyri\n              E\n            \n            :\n\t\t\t\t\t\n          The desmoid tumor: I. Incidence, sex-, age- and anatomical distribution in the Finnish population.\n\t\t\t\t\tAm J Clin Pathol77: 66,\n\t\t\t\t\t1982."},{"key":"i8750-7315-110-6-Article_14-b05","series-title":"Ann Surg Oncol","doi-asserted-by":"publisher","first-page":"2817","DOI":"10.1245\/s10434-015-4632-y","article-title":"Time trends in the incidence and treatment of extra-abdominal and abdominal aggressive fibromatosis: a population-based study","volume":"22","author":"van Broekhoven","year":"2015","unstructured":"van Broekhoven\n              DL\n            \n            \n              Grunhagen\n              DJ\n            \n            \n              den Bakker\n              MA\n            \n            :\n\t\t\t\t\t\n          Time trends in the incidence and treatment of extra-abdominal and abdominal aggressive fibromatosis: a population-based study.\n\t\t\t\t\tAnn Surg Oncol22: 2817,\n\t\t\t\t\t2015.\n\t\t\t\t10.1245\/s10434-015-4632-y26045393"},{"key":"i8750-7315-110-6-Article_14-b06","series-title":"Colorectal Dis","doi-asserted-by":"publisher","first-page":"1222","DOI":"10.1111\/j.1463-1318.2010.02345.x","article-title":"Risk factors predicting desmoid occurrence in patients with familial adenomatous polyposis: a meta-analysis","volume":"13","author":"Sinha","year":"2011","unstructured":"Sinha\n              A\n            \n            \n              Tekkis\n              PP\n            \n            \n              Gibbons\n              DC\n            \n            :\n\t\t\t\t\t\n          Risk factors predicting desmoid occurrence in patients with familial adenomatous polyposis: a meta-analysis.\n\t\t\t\t\tColorectal Dis13: 1222,\n\t\t\t\t\t2011.\n\t\t\t\t10.1111\/j.1463-1318.2010.02345.x20528895"},{"key":"i8750-7315-110-6-Article_14-b07","series-title":"Eur J Surg Oncol","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1053\/ejso.1999.0684","article-title":"Desmoid tumour: a pleomorphic lesion","volume":"25","author":"Kulaylat","year":"1999","unstructured":"Kulaylat\n              MN\n            \n            \n              Karakousis\n              CP\n            \n            \n              Keaney\n              CM\n            \n            :\n\t\t\t\t\t\n          Desmoid tumour: a pleomorphic lesion.\n\t\t\t\t\tEur J Surg Oncol25: 487,\n\t\t\t\t\t1999.\n\t\t\t\t1052759710.1053\/ejso.1999.0684"},{"key":"i8750-7315-110-6-Article_14-b08","series-title":"Eur J Surg Oncol","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.1016\/j.ejso.2016.02.012","article-title":"Extra-abdominal desmoid fibromatosis: a review of management, current guidance and unanswered questions","volume":"42","author":"Eastley","year":"2016","unstructured":"Eastley\n              N\n            \n            \n              McCulloch\n              T\n            \n            \n              Esler\n              C\n            \n            :\n\t\t\t\t\t\n          Extra-abdominal desmoid fibromatosis: a review of management, current guidance and unanswered questions.\n\t\t\t\t\tEur J Surg Oncol42: 1071,\n\t\t\t\t\t2016.\n\t\t\t\t2696530310.1016\/j.ejso.2016.02.012"},{"key":"i8750-7315-110-6-Article_14-b09","series-title":"Cancer","doi-asserted-by":"publisher","first-page":"2045","DOI":"10.1002\/(SICI)1097-0142(19991115)86:10<2045::AID-CNCR23>3.0.CO;2-F","article-title":"Extremity and trunk desmoid tumors: a multifactorial analysis of outcome","volume":"86","author":"Merchant","year":"1999","unstructured":"Merchant\n              NB\n            \n            \n              Lewis\n              JJ\n            \n            \n              Woodruff\n              JM\n            \n            :\n\t\t\t\t\t\n          Extremity and trunk desmoid tumors: a multifactorial analysis of outcome.\n\t\t\t\t\tCancer86: 2045,\n\t\t\t\t\t1999.\n\t\t\t\t10.1002\/(SICI)1097-0142(19991115)86:10<2045::AID-CNCR23>3.0.CO;2-F10570430"},{"key":"i8750-7315-110-6-Article_14-b10","series-title":"Br J Plast Surg","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1016\/j.bjps.2004.02.014","article-title":"Multicentric extra-abdominal desmoid tumours","volume":"57","author":"Wagstaff","year":"2004","unstructured":"Wagstaff\n              MJ\n            \n            \n              Raurell\n              A\n            \n            \n              Perks\n              AG:\n            \n          \n          Multicentric extra-abdominal desmoid tumours.\n\t\t\t\t\tBr J Plast Surg57: 362,\n\t\t\t\t\t2004.\n\t\t\t\t10.1016\/j.bjps.2004.02.01415145742"},{"key":"i8750-7315-110-6-Article_14-b11","series-title":"J Surg Oncol","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1002\/jso.21433","article-title":"Extra-abdominal desmoid tumors: a report of 234 cases","volume":"102","author":"Mankin","year":"2010","unstructured":"Mankin\n              HJ\n            \n            \n              Hornicek\n              FJ\n            \n            \n              Springfield\n              DS:\n            \n          \n          Extra-abdominal desmoid tumors: a report of 234 cases.\n\t\t\t\t\tJ Surg Oncol102: 380,\n\t\t\t\t\t2010.\n\t\t\t\t10.1002\/jso.2143319877160"},{"key":"i8750-7315-110-6-Article_14-b12","series-title":"Ann Oncol","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1093\/annonc\/mdg064","article-title":"The pharmacological treatment of aggressive fibromatosis: a systematic review","volume":"14","author":"Janinis","year":"2003","unstructured":"Janinis\n              J\n            \n            \n              Patriki\n              M\n            \n            \n              Vini\n              L\n            \n            :\n\t\t\t\t\t\n          The pharmacological treatment of aggressive fibromatosis: a systematic review.\n\t\t\t\t\tAnn Oncol14: 181,\n\t\t\t\t\t2003.\n\t\t\t\t1256264210.1093\/annonc\/mdg064"},{"key":"i8750-7315-110-6-Article_14-b13","series-title":"BMC Musculoskelet Disord","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/s12891-017-1924-3","article-title":"Desmoid tumours of the extremity and trunk: a retrospective study of 44 patients","volume":"19","author":"Wirth","year":"2018","unstructured":"Wirth\n              L\n            \n            \n              Klein\n              A\n            \n            \n              Baur-Melnyk\n              A\n            \n            :\n\t\t\t\t\t\n          Desmoid tumours of the extremity and trunk: a retrospective study of 44 patients.\n\t\t\t\t\tBMC Musculoskelet Disord19: 2,\n\t\t\t\t\t2018.\n\t\t\t\t10.1186\/s12891-017-1924-329304783"},{"key":"i8750-7315-110-6-Article_14-b14","series-title":"Bull Hosp Jt Dis Orthop Inst","first-page":"103","article-title":"Aggressive fibromatosis of the plantar aspect of the foot: a case report","volume":"47","author":"Alexander","year":"1987","unstructured":"Alexander\n              IJ\n            \n            \n              Johnson\n              KA\n            \n            \n              Shives\n              TC\n            \n            :\n\t\t\t\t\t\n          Aggressive fibromatosis of the plantar aspect of the foot: a case report.\n\t\t\t\t\tBull Hosp Jt Dis Orthop Inst47: 103,\n\t\t\t\t\t1987.\n\t\t\t\t2825871"},{"key":"i8750-7315-110-6-Article_14-b15","series-title":"Foot Ankle Int","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1177\/107110079601700407","article-title":"Recurring desmoid tumor of the foot: a case study","volume":"17","author":"Barbella","year":"1996","unstructured":"Barbella\n              R\n            \n            \n              Fox\n              IM:\n            \n          \n          Recurring desmoid tumor of the foot: a case study.\n\t\t\t\t\tFoot Ankle Int17: 221,\n\t\t\t\t\t1996.\n\t\t\t\t10.1177\/1071100796017004078696499"},{"key":"i8750-7315-110-6-Article_14-b16","series-title":"JAPMA","first-page":"70","article-title":"Extra-abdominal desmoid fibromatosis in the foot: a case study","volume":"101","author":"Macgill","year":"2011","unstructured":"Macgill\n              AA\n            \n            \n              Milione\n              VR\n            \n            \n              Sullivan\n              LG:\n            \n          \n          Extra-abdominal desmoid fibromatosis in the foot: a case study.\n\t\t\t\t\tJAPMA101: 70,\n\t\t\t\t\t2011."},{"key":"i8750-7315-110-6-Article_14-b17","series-title":"Orthopedics","first-page":"e1209","article-title":"Extra-abdominal periosteal desmoid tumor of the third toe","volume":"36","author":"Saleem","year":"2013","unstructured":"Saleem\n              O\n            \n            \n              Sayres\n              S\n            \n            \n              O'Malley\n              M:\n            \n          \n          Extra-abdominal periosteal desmoid tumor of the third toe.\n\t\t\t\t\tOrthopedics36: e1209,\n\t\t\t\t\t2013.\n\t\t\t\t24025015"},{"key":"i8750-7315-110-6-Article_14-b18","series-title":"Eur J Cancer","first-page":"127","article-title":"Desmoid Working Group: Management of sporadic desmoid-type fibromatosis: a European consensus approach based on patients' and professionals' expertise: a sarcoma patients EuroNet and European Organisation for Research and Treatment of Cancer\/Soft Tissue and Bone Sarcoma Group initiative","volume":"51","author":"Kasper","year":"2015","unstructured":"Kasper\n              B\n            \n            \n              Baumgarten\n              C\n            \n            \n              Bonvalot\n              S\n            \n            ;\n          \n          Desmoid Working Group: Management of sporadic desmoid-type fibromatosis: a European consensus approach based on patients' and professionals' expertise: a sarcoma patients EuroNet and European Organisation for Research and Treatment of Cancer\/Soft Tissue and Bone Sarcoma Group initiative.\n\t\t\t\t\tEur J Cancer51: 127,\n\t\t\t\t\t2015."},{"key":"i8750-7315-110-6-Article_14-b19","series-title":"Br J Radiol","doi-asserted-by":"publisher","first-page":"20150308","DOI":"10.1259\/bjr.20150308","article-title":"MRI may be used as a prognostic indicator in patients with extra-abdominal desmoid tumours","volume":"89","author":"Kamali","year":"2016","unstructured":"Kamali\n              F\n            \n            \n              Wang\n              WL\n            \n            \n              Guadagnolo\n              BA\n            \n            :\n\t\t\t\t\t\n          MRI may be used as a prognostic indicator in patients with extra-abdominal desmoid tumours.\n\t\t\t\t\tBr J Radiol89: 20150308,\n\t\t\t\t\t2016.\n\t\t\t\t2657728910.1259\/bjr.20150308"},{"key":"i8750-7315-110-6-Article_14-b20","series-title":"J Foot Ankle Surg","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1053\/j.jfas.2013.09.010","article-title":"Desmoplastic fibroma arising in the distal phalanx of the great toe: a case report","volume":"53","author":"Koba","year":"2014","unstructured":"Koba\n              T\n            \n            \n              Susa\n              M\n            \n            \n              Nakayama\n              R\n            \n            :\n\t\t\t\t\t\n          Desmoplastic fibroma arising in the distal phalanx of the great toe: a case report.\n\t\t\t\t\tJ Foot Ankle Surg53: 71,\n\t\t\t\t\t2014.\n\t\t\t\t10.1053\/j.jfas.2013.09.01024238967"},{"key":"i8750-7315-110-6-Article_14-b21","series-title":"Korean J Radiol","doi-asserted-by":"publisher","first-page":"963","DOI":"10.3348\/kjr.2013.14.6.963","article-title":"Desmoplastic fibroma of bone in a toe: radiographic and MRI findings","volume":"14","author":"Kim","year":"2013","unstructured":"Kim\n              OH\n            \n            \n              Kim\n              SJ\n            \n            \n              Kim\n              JY\n            \n            :\n\t\t\t\t\t\n          Desmoplastic fibroma of bone in a toe: radiographic and MRI findings.\n\t\t\t\t\tKorean J Radiol14: 963,\n\t\t\t\t\t2013.\n\t\t\t\t10.3348\/kjr.2013.14.6.963"},{"key":"i8750-7315-110-6-Article_14-b22","series-title":"Foot Ankle Int","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1177\/107110079902000103","article-title":"Fibromatosis of the plantar fascia: diagnosis and indications for surgical treatment","volume":"20","author":"D\u00fcrr","year":"1999","unstructured":"D\u00fcrr\n              HR\n            \n            \n              Kr\u00f6del\n              A\n            \n            \n              Trouillier\n              H\n            \n            :\n\t\t\t\t\t\n          Fibromatosis of the plantar fascia: diagnosis and indications for surgical treatment.\n\t\t\t\t\tFoot Ankle Int20: 13,\n\t\t\t\t\t1999.\n\t\t\t\t10.1177\/1071100799020001039921766"},{"key":"i8750-7315-110-6-Article_14-b23","series-title":"J Surg Oncol","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1002\/jso.23343","article-title":"Surgical outcome of desmoid tumors: adjuvant radiotherapy delayed the recurrence, but did not affect long-term outcomes","volume":"108","author":"Shin","year":"2013","unstructured":"Shin\n              SH\n            \n            \n              Ko\n              KR\n            \n            \n              Cho\n              SK\n            \n            :\n\t\t\t\t\t\n          Surgical outcome of desmoid tumors: adjuvant radiotherapy delayed the recurrence, but did not affect long-term outcomes.\n\t\t\t\t\tJ Surg Oncol108: 28,\n\t\t\t\t\t2013.\n\t\t\t\t10.1002\/jso.23343"},{"key":"i8750-7315-110-6-Article_14-b24","series-title":"Eur J Surg Oncol","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1016\/j.ejso.2004.01.010","article-title":"Evaluation of the long term outcome of patients with extremity desmoids","volume":"30","author":"Chew","year":"2004","unstructured":"Chew\n              C\n            \n            \n              Reid\n              R\n            \n            \n              O'Dwyer\n              PJ:\n            \n          \n          Evaluation of the long term outcome of patients with extremity desmoids.\n\t\t\t\t\tEur J Surg Oncol30: 428,\n\t\t\t\t\t2004.\n\t\t\t\t10.1016\/j.ejso.2004.01.010"},{"key":"i8750-7315-110-6-Article_14-b25","series-title":"Ann Surg Oncol","doi-asserted-by":"publisher","first-page":"4036","DOI":"10.1245\/s10434-012-2634-6","article-title":"Management and recurrence patterns of desmoids tumors: a multi-institutional analysis of 211 patients","volume":"19","author":"Peng","year":"2012","unstructured":"Peng\n              PD\n            \n            \n              Hyder\n              O\n            \n            \n              Mavros\n              MN\n            \n            :\n\t\t\t\t\t\n          Management and recurrence patterns of desmoids tumors: a multi-institutional analysis of 211 patients.\n\t\t\t\t\tAnn Surg Oncol19: 4036,\n\t\t\t\t\t2012.\n\t\t\t\t2297250710.1245\/s10434-012-2634-6"},{"key":"i8750-7315-110-6-Article_14-b26","series-title":"Eur J Surg Oncol","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1016\/j.ejso.2014.02.226","article-title":"Extra-abdominal desmoid fibromatosis: a sarcoma unit review of practice, long term recurrence rates and survival","volume":"40","author":"Eastley","year":"2014","unstructured":"Eastley\n              N\n            \n            \n              Aujla\n              R\n            \n            \n              Silk\n              R\n            \n            :\n\t\t\t\t\t\n          Extra-abdominal desmoid fibromatosis: a sarcoma unit review of practice, long term recurrence rates and survival.\n\t\t\t\t\tEur J Surg Oncol40: 1125,\n\t\t\t\t\t2014.\n\t\t\t\t10.1016\/j.ejso.2014.02.22624612653"},{"key":"i8750-7315-110-6-Article_14-b27","series-title":"Arch Orthop Trauma Surg","doi-asserted-by":"publisher","first-page":"929","DOI":"10.1007\/s00402-008-0750-3","article-title":"Surgical treatment for local control of extremity and trunk desmoid tumors","volume":"129","author":"Shido","year":"2009","unstructured":"Shido\n              Y\n            \n            \n              Nishida\n              Y\n            \n            \n              Nakashima\n              H\n            \n            :\n\t\t\t\t\t\n          Surgical treatment for local control of extremity and trunk desmoid tumors.\n\t\t\t\t\tArch Orthop Trauma Surg129: 929,\n\t\t\t\t\t2009.\n\t\t\t\t10.1007\/s00402-008-0750-318810472"},{"key":"i8750-7315-110-6-Article_14-b28","series-title":"J Bone Joint Surg Am","doi-asserted-by":"publisher","first-page":"848","DOI":"10.2106\/00004623-199606000-00007","article-title":"Local control of extra-abdominal desmoid tumors","volume":"78","author":"Pritchard","year":"1996","unstructured":"Pritchard\n              DJ\n            \n            \n              Nascimento\n              AG\n            \n            \n              Petersen\n              IA:\n            \n          \n          Local control of extra-abdominal desmoid tumors.\n\t\t\t\t\tJ Bone Joint Surg Am78: 848,\n\t\t\t\t\t1996.\n\t\t\t\t10.2106\/00004623-199606000-000078666602"},{"key":"i8750-7315-110-6-Article_14-b29","series-title":"J Surg Oncol","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1002\/jso.20057","article-title":"Margins in extra-abdominal desmoid tumors: a comparative analysis","volume":"86","author":"Leithner","year":"2004","unstructured":"Leithner\n              A\n            \n            \n              Gapp\n              M\n            \n            \n              Leithner\n              K\n            \n            :\n\t\t\t\t\t\n          Margins in extra-abdominal desmoid tumors: a comparative analysis.\n\t\t\t\t\tJ Surg Oncol86: 152,\n\t\t\t\t\t2004.\n\t\t\t\t10.1002\/jso.2005715170654"},{"key":"i8750-7315-110-6-Article_14-b30","series-title":"J Surg Oncol","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1002\/jso.21033","article-title":"Multimodality management of desmoid tumors: how important is a negative surgical margin?","volume":"98","author":"Melis","year":"2008","unstructured":"Melis\n              M\n            \n            \n              Zager\n              JS\n            \n            \n              Sondak\n              VK:\n            \n          \n          Multimodality management of desmoid tumors: how important is a negative surgical margin?\n          J Surg Oncol\n          98\n          : \n          594,\n\t\t\t\t\t2008.\n\t\t\t\t10.1002\/jso.2103319072851"},{"key":"i8750-7315-110-6-Article_14-b31","series-title":"J Clin Oncol","doi-asserted-by":"publisher","first-page":"1390","DOI":"10.1200\/JCO.2003.05.150","article-title":"Quality of surgery and outcome in extra-abdominal aggressive fibromatosis: a series of patients surgically treated at a single institution","volume":"21","author":"Gronchi","year":"2003","unstructured":"Gronchi\n              A\n            \n            \n              Casali\n              PG\n            \n            \n              Mariani\n              L\n            \n            :\n\t\t\t\t\t\n          Quality of surgery and outcome in extra-abdominal aggressive fibromatosis: a series of patients surgically treated at a single institution.\n\t\t\t\t\tJ Clin Oncol21: 1390,\n\t\t\t\t\t2003.\n\t\t\t\t10.1200\/JCO.2003.05.150"},{"key":"i8750-7315-110-6-Article_14-b32","series-title":"Int J Radiat Oncol Biol Phys","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1016\/S0360-3016(98)00285-5","article-title":"Radiation therapy in the management of desmoid tumors","volume":"42","author":"Ballo","year":"1998","unstructured":"Ballo\n              MT\n            \n            \n              Zagars\n              GK\n            \n            \n              Pollack\n              A:\n            \n          \n          Radiation therapy in the management of desmoid tumors.\n\t\t\t\t\tInt J Radiat Oncol Biol Phys42: 1007,\n\t\t\t\t\t1998.\n\t\t\t\t10.1016\/S0360-3016(98)00285-59869223"},{"key":"i8750-7315-110-6-Article_14-b33","series-title":"Radiat Oncol","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1186\/1748-717X-2-12","article-title":"The impact of radiotherapy in the treatment of desmoid tumours: an international survey of 110 patients: a study of the Rare Cancer Network","volume":"2","author":"Baumert","year":"2007","unstructured":"Baumert\n              BG\n            \n            \n              Spahr\n              MO\n            \n            \n              Von Hochstetter\n              A\n            \n            :\n\t\t\t\t\t\n          The impact of radiotherapy in the treatment of desmoid tumours: an international survey of 110 patients: a study of the Rare Cancer Network.\n\t\t\t\t\tRadiat Oncol2: 12,\n\t\t\t\t\t2007.\n\t\t\t\t10.1186\/1748-717X-2-1217343751"},{"key":"i8750-7315-110-6-Article_14-b34","series-title":"J Clin Oncol","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1200\/JCO.1999.17.1.158","article-title":"Desmoid tumor: prognostic factors and outcome after surgery, radiation therapy, or combined surgery and radiation therapy","volume":"17","author":"Ballo","year":"1999","unstructured":"Ballo\n              MT\n            \n            \n              Zagars\n              GK\n            \n            \n              Pollack\n              A\n            \n            :\n\t\t\t\t\t\n          Desmoid tumor: prognostic factors and outcome after surgery, radiation therapy, or combined surgery and radiation therapy.\n\t\t\t\t\tJ Clin Oncol17: 158,\n\t\t\t\t\t1999.\n\t\t\t\t10.1200\/JCO.1999.17.1.158"},{"key":"i8750-7315-110-6-Article_14-b35","series-title":"Int J Radiat Oncol Biol Phys","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1016\/S0360-3016(97)00845-6","article-title":"Individualizing management of aggressive fibromatoses","volume":"40","author":"Spear","year":"1998","unstructured":"Spear\n              MA\n            \n            \n              Jennings\n              LC\n            \n            \n              Mankin\n              HJ\n            \n            :\n\t\t\t\t\t\n          Individualizing management of aggressive fibromatoses.\n\t\t\t\t\tInt J Radiat Oncol Biol Phys40: 637,\n\t\t\t\t\t1998.\n\t\t\t\t948661410.1016\/S0360-3016(97)00845-6"},{"key":"i8750-7315-110-6-Article_14-b36","series-title":"J Clin Oncol","doi-asserted-by":"publisher","first-page":"1785","DOI":"10.1200\/JCO.2006.10.5015","article-title":"Optimizing treatment of desmoid tumors","volume":"25","author":"Lev","year":"2007","unstructured":"Lev\n              D\n            \n            \n              Kotilingam\n              D\n            \n            \n              Wei\n              C\n            \n            :\n\t\t\t\t\t\n          Optimizing treatment of desmoid tumors.\n\t\t\t\t\tJ Clin Oncol25: 1785,\n\t\t\t\t\t2007.\n\t\t\t\t1747087010.1200\/JCO.2006.10.5015"},{"key":"i8750-7315-110-6-Article_14-b37","series-title":"Fam Cancer","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1007\/s10689-015-9830-z","article-title":"Long-term outcome of sporadic and FAP-associated desmoid tumors treated with high-dose selective estrogen receptor modulators and sulindac: a single-center long-term observational study in 134 patients","volume":"15","author":"Quast","year":"2016","unstructured":"Quast\n              DR\n            \n            \n              Schneider\n              R\n            \n            \n              Burdzik\n              E\n            \n            :\n\t\t\t\t\t\n          Long-term outcome of sporadic and FAP-associated desmoid tumors treated with high-dose selective estrogen receptor modulators and sulindac: a single-center long-term observational study in 134 patients.\n\t\t\t\t\tFam Cancer15: 31,\n\t\t\t\t\t2016.\n\t\t\t\t2627586810.1007\/s10689-015-9830-z"},{"key":"i8750-7315-110-6-Article_14-b38","series-title":"Ann Oncol","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1093\/annonc\/mdq341","article-title":"Imatinib for progressive and recurrent aggressive fibromatosis (desmoid tumors): an FNCLCC\/French Sarcoma Group phase II trial with a long-term follow-up","volume":"22","author":"Penel","year":"2011","unstructured":"Penel\n              N\n            \n            \n              Le Cesne\n              A\n            \n            \n              Bui\n              BN\n            \n            :\n\t\t\t\t\t\n          Imatinib for progressive and recurrent aggressive fibromatosis (desmoid tumors): an FNCLCC\/French Sarcoma Group phase II trial with a long-term follow-up.\n\t\t\t\t\tAnn Oncol22: 452,\n\t\t\t\t\t2011.\n\t\t\t\t2062200010.1093\/annonc\/mdq341"},{"key":"i8750-7315-110-6-Article_14-b39","series-title":"J Bone Joint Surg Am","doi-asserted-by":"publisher","first-page":"631","DOI":"10.2106\/JBJS.M.00988","article-title":"Wait-and-see policy as a first-line management for extra-abdominal desmoid tumors","volume":"96","author":"Briand","year":"2014","unstructured":"Briand\n              S\n            \n            \n              Barbier\n              O\n            \n            \n              Biau\n              D\n            \n            :\n\t\t\t\t\t\n          Wait-and-see policy as a first-line management for extra-abdominal desmoid tumors.\n\t\t\t\t\tJ Bone Joint Surg Am96: 631,\n\t\t\t\t\t2014.\n\t\t\t\t2474065910.2106\/JBJS.M.00988"},{"key":"i8750-7315-110-6-Article_14-b40","series-title":"J Surg Res","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.jss.2016.06.028","article-title":"Conservative management of desmoid tumors is safe and effective","volume":"205","author":"Park","year":"2016","unstructured":"Park\n              JS\n            \n            \n              Nakache\n              YP\n            \n            \n              Katz\n              J\n            \n            :\n\t\t\t\t\t\n          Conservative management of desmoid tumors is safe and effective.\n\t\t\t\t\tJ Surg Res205: 115,\n\t\t\t\t\t2016.\n\t\t\t\t2762100710.1016\/j.jss.2016.06.028"},{"key":"i8750-7315-110-6-Article_14-b41","series-title":"BMC Cancer","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1186\/s12885-016-2704-4","article-title":"Tailored beta-catenin mutational approach in extra-abdominal sporadic desmoid tumor patients without therapeutic intervention","volume":"16","author":"van Broekhoven","year":"2016","unstructured":"van Broekhoven\n              DL\n            \n            \n              Grunhagenl\n              DJ\n            \n            \n              van Dalen\n              T\n            \n            :\n\t\t\t\t\t\n          Tailored beta-catenin mutational approach in extra-abdominal sporadic desmoid tumor patients without therapeutic intervention.\n\t\t\t\t\tBMC Cancer16: 686,\n\t\t\t\t\t2016.\n\t\t\t\t2756571810.1186\/s12885-016-2704-4"}],"container-title":["Journal of the American Podiatric Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/japmaonline.org\/view\/journals\/apms\/110\/6\/i8750-7315-110-6-article_14.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/japma\/article-pdf\/doi\/10.7547\/19-042\/2679525\/i8750-7315-110-6-article_14.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/japmaonline.org\/downloadpdf\/journals\/apms\/110\/6\/i8750-7315-110-6-article_14.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/japmaonline.org\/downloadpdf\/journals\/apms\/110\/6\/i8750-7315-110-6-article_14.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T10:18:05Z","timestamp":1783505885000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1930-8264\/110\/6\/19042"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":41,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.7547\/19-042","relation":{},"ISSN":["8750-7315"],"issn-type":[{"value":"8750-7315","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11]]}}}