{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T11:14:53Z","timestamp":1783509293390,"version":"3.55.0"},"reference-count":19,"publisher":"MDPI AG","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    The purpose of this study was to evaluate the effectiveness of tap water iontophoresis as a treatment for plantar hyperhidrosis.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    Thirty participants living with idiopathic plantar hyperhidrosis and consented to undergo treatment using iontophoresis were recruited. The Hyperhidrosis Disease Severity Score was used to evaluate the severity of the condition before and after treatment.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    Tap water iontophoresis was found to be effective in the treatment of plantar hyperhidrosis in the study group (\n                    <jats:italic>P<\/jats:italic>\n                    = .005).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    Treatment with iontophoresis led to the reduction of disease severity and improvement of quality of life, and it is a safe, easy-to-use method with minimal side effects. This technique should be considered before the use of systemic or aggressive surgical interventions, which could have potentially more severe side effects.\n                  <\/jats:p>","DOI":"10.7547\/21-003","type":"journal-article","created":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T19:47:11Z","timestamp":1678391231000},"source":"Crossref","is-referenced-by-count":0,"title":["Effectiveness of Iontophoresis in Treating Plantar Hyperhidrosis"],"prefix":"10.3390","volume":"113","author":[{"given":"Cynthia","family":"Formosa","sequence":"first","affiliation":[{"name":"University of Malta, Faculty of Health Sciences, Msida, Malta."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire Saliba","family":"Thorne","sequence":"additional","affiliation":[{"name":"University of Malta, Faculty of Health Sciences, Msida, Malta."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfred","family":"Gatt","sequence":"additional","affiliation":[{"name":"University of Malta, Faculty of Health Sciences, Msida, Malta."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","reference":[{"key":"B1","series-title":"Botulinum Toxin in Clinical Dermatology","author":"Benedetto AV","year":"2006","unstructured":"Benedetto AV: Botulinum Toxin in Clinical Dermatology, Taylor & Francis, London, 2006."},{"key":"B2","series-title":"Am Fam Physician","first-page":"1117","article-title":"Palmoplantar hyperhidrosis: a therapeutic challenge","volume":"69","author":"Thomas S","year":"2004","unstructured":"Thomas S, Brown J, Vafaie J, : Palmoplantar hyperhidrosis: a therapeutic challenge. 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