{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T11:14:46Z","timestamp":1783509286417,"version":"3.55.0"},"reference-count":9,"publisher":"MDPI AG","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    After partial bone resection for osteomyelitis there is a high rate of osteomyelitis occurrence in the remaining bone due to adherent bacterial biofilm, dysvascular infected spongiosum bone, and absence of a surgical technique that can prevent osteomyelitis developing in the remaining bone.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    Presented is a surgical procedure using a dicalcium phosphate bone void filler putty with antibiotics placed into the remaining bone to prevent the development of osteomyelitis, therefore preventing amputation.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    This procedure has an osteomyelitis eradication rate of 94.8% and also decreases the rate of lower-extremity amputations.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    This procedure provides a single stage surgical technique for infected open bone defects decreasing the previously reported high osteomyelitis reoccurrence rate of 57.1% to 5.2%.\n                  <\/jats:p>","DOI":"10.7547\/21-038","type":"journal-article","created":{"date-parts":[[2022,12,14]],"date-time":"2022-12-14T14:26:52Z","timestamp":1671028012000},"source":"Crossref","is-referenced-by-count":0,"title":["Decreasing Osteomyelitis Occurrence in Remaining Bone After Partially Resected Infected Bone"],"prefix":"10.3390","volume":"112","author":[{"given":"Jeffrey C.","family":"Karr","sequence":"first","affiliation":[{"name":"The Osteomyelitis Center of Central Florida, 5421 S Florida Ave, Lakeland, FL 33813"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","reference":[{"key":"B1","series-title":"J Foot Ankle Surg","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1053\/j.jfas.2010.12.009","article-title":"The effect of residual osteomyelitis at the resection margin in patients with surgically treated diabetic foot infection","volume":"50","author":"Kowalski TJ","year":"2011","unstructured":"Kowalski TJ, Matsuda M, Sorenson MD, : The effect of residual osteomyelitis at the resection margin in patients with surgically treated diabetic foot infection. J Foot Ankle Surg 50: 171, 2011.10.1053\/j.jfas.2010.12.009"},{"key":"B2","series-title":"J Foot Ankle Surg","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1053\/j.jfas.2012.06.017","article-title":"Rate of residual osteomyelitis after partial foot amputation in diabetic patients: a standardized method for evaluating bone margins with intraoperative culture","volume":"51","author":"Atway S","year":"2012","unstructured":"Atway S, Nerone VS, Springer KD, : Rate of residual osteomyelitis after partial foot amputation in diabetic patients: a standardized method for evaluating bone margins with intraoperative culture. J Foot Ankle Surg 51: 749, 2012.10.1053\/j.jfas.2012.06.017"},{"key":"B3","series-title":"Reconstr Surg Traumatol","first-page":"36","article-title":"Local antibiotic therapy using gentamicin-PMMA chains in post-traumatic bone infections: short and long-term results","volume":"20","author":"Jenny G","year":"1988","unstructured":"Jenny G: Local antibiotic therapy using gentamicin-PMMA chains in post-traumatic bone infections: short and long-term results. Reconstr Surg Traumatol 20: 36, 1988."},{"key":"B4","series-title":"Diabetes Care","doi-asserted-by":"publisher","first-page":"e79","DOI":"10.2337\/dc14-3100","article-title":"Use of highly purified synthetic calcium sulfate impregnated with antibiotics for the management of diabetic foot ulcers complicated by osteomyelitis","volume":"38","author":"Jogia RM","year":"2015","unstructured":"Jogia RM, Modha DE, Nisal K, : Use of highly purified synthetic calcium sulfate impregnated with antibiotics for the management of diabetic foot ulcers complicated by osteomyelitis. Diabetes Care 38: e79, 2015.10.2337\/dc14-3100"},{"key":"B5","series-title":"Int J Low Extrem Wounds","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1177\/1534734616661058","article-title":"Treatment failure and leg amputation among patients with foot osteomyelitis","volume":"15","author":"Barshes NR","year":"2016","unstructured":"Barshes NR, Mindru C, Ashong C, : Treatment failure and leg amputation among patients with foot osteomyelitis. Int J Low Extrem Wounds 15: 303, 2016.10.1177\/1534734616661058"},{"key":"B6","series-title":"Diabetes Care","doi-asserted-by":"publisher","first-page":"566","DOI":"10.2337\/diacare.29.03.06.dc05-1992","article-title":"Risk of reamputation in diabetic patients stratified by limb and level of amputation: a 10-year observation","volume":"29","author":"Lee S","year":"2006","unstructured":"Lee S, Harkless LB: Risk of reamputation in diabetic patients stratified by limb and level of amputation: a 10-year observation. Diabetes Care 29: 566, 2006.10.2337\/diacare.29.03.06.dc05-1992"},{"key":"B7","series-title":"Diabetes Care","doi-asserted-by":"publisher","first-page":"566","DOI":"10.2337\/diacare.29.03.06.dc05-1992","article-title":"Risk of reamputation in diabetic patients stratified by limb and level of amputation: a 10-year observation","volume":"29","author":"Izumi Y","year":"2006","unstructured":"Izumi Y, Satterfield K, Lee S, : Risk of reamputation in diabetic patients stratified by limb and level of amputation: a 10-year observation. Diabetes Care 29: 566, 2006.10.2337\/diacare.29.03.06.dc05-1992"},{"key":"B8","series-title":"Plast Reconstr Surg","doi-asserted-by":"publisher","first-page":"190S","DOI":"10.1097\/PRS.0b013e3182025070","article-title":"Surgical treatment of osteomyelitis","volume":"127","author":"Cierny G III","year":"2011","unstructured":"Cierny G III. Surgical treatment of osteomyelitis. Plast Reconstr Surg 127: 190S, 2011.10.1097\/PRS.0b013e3182025070"},{"key":"B9","series-title":"Surg Infect","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1089\/sur.2016.189","article-title":"Optimizing vancomycin release from calcium phosphate-based cement by carboxymethyl cellulose for prevention of osteomyelitis","volume":"18","author":"Lin BR","year":"2017","unstructured":"Lin BR, Caldwell C, Bhaduri S, : Optimizing vancomycin release from calcium phosphate-based cement by carboxymethyl cellulose for prevention of osteomyelitis. Surg Infect 18: 221, 2017.10.1089\/sur.2016.189"}],"container-title":["Journal of the American Podiatric Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/japmaonline.org\/view\/journals\/apms\/112\/6\/21-038.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/japmaonline.org\/downloadpdf\/journals\/apms\/112\/6\/21-038.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/japmaonline.org\/downloadpdf\/journals\/apms\/112\/6\/21-038.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T10:18:59Z","timestamp":1783505939000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1930-8264\/112\/6\/21038"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":9,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.7547\/21-038","relation":{},"ISSN":["8750-7315"],"issn-type":[{"value":"8750-7315","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]}}}