{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T11:15:01Z","timestamp":1783509301467,"version":"3.55.0"},"reference-count":32,"publisher":"MDPI AG","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    The purpose of this study was to determine the association of preulcerative foot care and outcomes of diabetic foot ulcerations (DFUs).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    This retrospective cohort study using the Mariner all-payers claims data set included participants with a new DFU from 2010 to 2019. Patients were stratified into two cohorts (foot care and control) based on whether they had received any outpatient foot care within 12 months before DFU. Adjusted comparison was performed by propensity matching for age, sex, and the Charlson Comorbidity Index (1:2 ratio). Kaplan-Meier estimates and logistic regression examined the association between foot care and outcomes of DFUs.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    Of the 307,131 patients in the study cohort, 4.7% (\n                    <jats:italic>n<\/jats:italic>\n                    = 14,477) received outpatient preulcerative foot care within the 12-month period before DFU. The rate of major amputation was 1.8% (foot care, 1.2%), and 9.0% of patients had hospitalizations for foot infection within 12 months after DFU (foot care, 7.8%). In the study cohort, patients who received pre-DFU foot care had greater major amputation-free survival (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; .001) on Kaplan-Meier estimate. In both the study and matched cohorts, multivariable analysis demonstrated that foot care was associated with lower odds of major amputation for both study (odds ratio [OR], 0.56; 95% confidence interval [CI], 0.48\u20130.66) and matched (OR, 0.61; 95% CI, 0.51\u20130.72) cohorts, and lower odds of hospitalizations for a foot infection in both study (OR, 0.91; 95% CI, 0.86\u20130.96) and matched (OR, 0.88, 95% CI, 0.82\u20130.94) cohorts.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    Among patients with a new DFU, those who received outpatient preulcerative foot care within 12 months of diagnosis had lower risks of major amputation and hospitalizations for foot infection.\n                  <\/jats:p>","DOI":"10.7547\/22-071","type":"journal-article","created":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T12:35:21Z","timestamp":1715862921000},"source":"Crossref","is-referenced-by-count":4,"title":["Association of Preulcerative Foot Care and Outcomes of Diabetic Foot Ulceration"],"prefix":"10.3390","volume":"114","author":[{"given":"Tze-Woei","family":"Tan","sequence":"first","affiliation":[{"name":"University of Southern California, Los Angeles, CA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey P.","family":"Tolson","sequence":"additional","affiliation":[{"name":"University of Arizona, Tucson, AZ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan C. Arias","family":"Aristizabal","sequence":"additional","affiliation":[{"name":"University of Arizona, Tucson, AZ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego J.","family":"Urbina","sequence":"additional","affiliation":[{"name":"University of Arizona, Tucson, AZ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah A.","family":"Fermawi","sequence":"additional","affiliation":[{"name":"University of Arizona, Tucson, AZ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig","family":"Weinkauf","sequence":"additional","affiliation":[{"name":"University of Arizona, Tucson, AZ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David G","family":"Marrero","sequence":"additional","affiliation":[{"name":"University of Arizona, Tucson, AZ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David G.","family":"Armstrong","sequence":"additional","affiliation":[{"name":"University of Arizona, Tucson, AZ."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","reference":[{"key":"B1","series-title":"Phys Ther","first-page":"1436","article-title":"Comprehensive foot examination and risk assessment. A report of the Task Force of the Foot Care Interest Group of the American Diabetes Association, with endorsement by the American Association of Clinical Endocrinologists","volume":"88","author":"Boulton AJ","year":"2008","unstructured":"Boulton AJ, Armstrong DG, Albert SF, et al: Comprehensive foot examination and risk assessment. A report of the Task Force of the Foot Care Interest Group of the American Diabetes Association, with endorsement by the American Association of Clinical Endocrinologists. Phys Ther 88: 1436, 2008."},{"key":"B2","series-title":"Int J Endocrinol","first-page":"7631659,","article-title":"Incidence and risk factors of diabetic foot ulcer: a population-based diabetic foot cohort (ADFC study)\u2014two-year follow-up study","volume":"2018","author":"Yazdanpanah L","unstructured":"Yazdanpanah L, Shahbazian H, Nazari I, et al: Incidence and risk factors of diabetic foot ulcer: a population-based diabetic foot cohort (ADFC study)\u2014two-year follow-up study. Int J Endocrinol 2018: 7631659, 2018."},{"key":"B3","series-title":"N Engl J Med","first-page":"2367","article-title":"Diabetic foot ulcers and their recurrence","volume":"376","author":"Armstrong DG","year":"2017","unstructured":"Armstrong DG, Boulton AJM, Bus SA: Diabetic foot ulcers and their recurrence. N Engl J Med 376: 2367, 2017."},{"key":"B4","series-title":"Diabetologia","first-page":"747","article-title":"Prediction of outcome in individuals with diabetic foot ulcers: focus on the differences between individuals with and without peripheral arterial disease. The EURODIALE Study","volume":"51","author":"Prompers L","year":"2008","unstructured":"Prompers L, Schaper N, Apelqvist J, et al: Prediction of outcome in individuals with diabetic foot ulcers: focus on the differences between individuals with and without peripheral arterial disease. The EURODIALE Study. Diabetologia 51: 747, 2008."},{"key":"B5","series-title":"J Foot Ankle Res","first-page":"16,","article-title":"Five year mortality and direct costs of care for people with diabetic foot complications are comparable to cancer","volume":"13","author":"Armstrong DG","year":"2020","unstructured":"Armstrong DG, Swerdlow MA, Armstrong AA, et al: Five year mortality and direct costs of care for people with diabetic foot complications are comparable to cancer. J Foot Ankle Res 13: 16, 2020."},{"key":"B6","series-title":"I: from ulceration to death, a systematic review. Int Wound J","first-page":"892,","article-title":"The impact of foot ulceration and amputation on mortality in diabetic patients","volume":"13","author":"Jupiter DC","year":"2016","unstructured":"Jupiter DC, Thorud JC, Buckley CJ, et al: The impact of foot ulceration and amputation on mortality in diabetic patients. I: from ulceration to death, a systematic review. Int Wound J 13: 892, 2016."},{"key":"B7","series-title":"Am Heart J","first-page":"809","article-title":"High mortality risks after major lower extremity amputation in Medicare patients with peripheral artery disease","volume":"165","author":"Jones WS","year":"2013","unstructured":"Jones WS, Patel MR, Dai D, et al: High mortality risks after major lower extremity amputation in Medicare patients with peripheral artery disease. Am Heart J 165: 809, 2013."},{"key":"B8","series-title":"JAPMA 104:","first-page":"1,","article-title":"The amputation prevention initiative","author":"Cook EA","year":"2014","unstructured":"Cook EA, Cook JJ, Labre MP, et al: The amputation prevention initiative. JAPMA 104: 1, 2014."},{"key":"B9","series-title":"Diabetes Care","first-page":"917,","article-title":"Economic costs of diabetes in the U.S. in 2017","volume":"41","year":"2018","unstructured":"Association AD: Economic costs of diabetes in the U.S. in 2017. Diabetes Care 41: 917, 2018."},{"key":"B10","article-title":"US Department of Health and Human Services. National Diabetes Statistics Report","year":"2020","unstructured":"Centers for Disease Control and Prevention, US Department of Health and Human Services. National Diabetes Statistics Report 2020. Available at: https:\/\/www.cdc.gov\/diabetes\/pdfs\/data\/statistics\/national-diabetes-statistics-report.pdf. Accessed December 1, 2022."},{"issue":"suppl 1","key":"B11","series-title":"Diabetes Care","first-page":"S55,","article-title":"Preventive foot care in people with diabetes","volume":"23","year":"2000","unstructured":"American Diabetes Association. Preventive foot care in people with diabetes. 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Wound Repair Regen 7: 7, 1999."},{"key":"B18","unstructured":"PearlDiver Mariner database and research software [computer program]."},{"key":"B19","series-title":"Int J Surg","first-page":"1500","article-title":"Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration","volume":"12","author":"Vandenbroucke JP","year":"2014","unstructured":"Vandenbroucke JP, von Elm E, Altman DG, et al: Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration. Int J Surg 12: 1500, 2014."},{"issue":"suppl 1","key":"B20","series-title":"Diabetes Care","first-page":"S124,","article-title":"Microvascular complications and foot care: standards of medical care in diabetes\u20142019","volume":"42","year":"2018","unstructured":"American Diabetes Association. Microvascular complications and foot care: standards of medical care in diabetes\u20142019. 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