{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T10:22:49Z","timestamp":1783506169297,"version":"3.55.0"},"reference-count":22,"publisher":"MDPI AG","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,11,1]]},"abstract":"\n \n Background<\/jats:title>\n We sought to demonstrate the healing efficacy of an antimicrobial hydrogel containing Oakin, an oak extract, to heal postoperative partial and total chemical matrixectomies.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Sixty participants were eligible for this open-label prospective study by having an ingrown toenail and a willingness to have the ingrown portion of the nail or the entire toenail permanently removed. All of the participants underwent a similar nail surgery, were provided a postoperative kit that included the study hydrogel, and received the same sheet of instructions for aftercare.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Fifty-four participants could be contacted for follow-up and final evaluation; 54% (n = 29) were men and 46% (n = 25) were women. Eighty-nine partial hallux nail avulsions with phenol matrixectomy were performed. The median \u00b1 SD time to healing was 7.00 \u00b1 0.00 days for 80% of participants (n =\u2009 43) and 8.85 \u00b1 4.15 days for 98% (n = 53). An analysis of variance showed that the proportion healed time trend is significant (F1,53 = 79.265; P &lt; .001).<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n The study hydrogel's ability to stop phenol's caustic activity is clinically beneficial in phenol matrixectomy aftercare. Providing each participant with a kit that included the same dressing supplies yielded consistent aftercare outcomes and 98% patient satisfaction (n = 53). The findings show that the Oakin-containing hydrogel was efficacious in healing phenol matrixectomies without the need for soaking. Furthermore, we suggest that the study hydrogel could also reduce healing times.<\/jats:p>\n <\/jats:sec>","DOI":"10.7547\/8750-7315-104.6.617","type":"journal-article","created":{"date-parts":[[2014,12,16]],"date-time":"2014-12-16T17:30:08Z","timestamp":1418751008000},"page":"617-621","source":"Crossref","is-referenced-by-count":1,"title":["Healing Efficacy and Participant Outcomes of Chemical Matrixectomies Using a Hydrogel Containing Oakin"],"prefix":"10.3390","volume":"104","author":[{"given":"Kristina N.","family":"Barreiro","sequence":"first","affiliation":[{"name":"Jackson North Hospital, Miami Shores, FL."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masoud","family":"Moradi","sequence":"first","affiliation":[{"name":"Barry University, Miami Shores, FL."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Merrill","sequence":"first","affiliation":[{"name":"Barry University, Miami Shores, FL."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Losito","sequence":"first","affiliation":[{"name":"Barry University, Miami Shores, FL."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Southerland","sequence":"first","affiliation":[{"name":"Barry University, Miami Shores, FL."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Buckley","sequence":"first","affiliation":[{"name":"Private Practice, Sarasota, FL."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","reference":[{"key":"ref01","doi-asserted-by":"crossref","first-page":"287","DOI":"10.7547\/87507315-92-5-287","article-title":"Chemical matrixectomy for ingrown toenails: is there an evidence basis to guide therapy?","volume":"92","author":"Espensen","year":"2002","journal-title":"JAPMA"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"452","DOI":"10.7547\/87507315-88-9-452","article-title":"Improved healing with a collagen-alginate dressing in the chemical matrixectomy","volume":"88","author":"Van Gils","year":"1998","journal-title":"JAPMA"},{"key":"ref131","first-page":"680","article-title":"Comparison of phenol and sodium hydroxide chemical matricectomies for the treatment of ingrowing toenails","volume":"33","author":"Bostanci","year":"2007","journal-title":"Dermatol Surg"},{"key":"ref141","doi-asserted-by":"crossref","first-page":"32","DOI":"10.7241\/ourd.20131.06","article-title":"A study on the surgical treatment of ingrowing toe nail with nail excision with chemical matricectomy versus nail excision alone","volume":"4","author":"Talwar","year":"2012","journal-title":"Our Dermatol Online"},{"key":"ref161","first-page":"233","article-title":"The phenol-alcohol technique 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extract","volume":"23","author":"Moore","year":"2010","journal-title":"Adv Skin Wound Care"},{"key":"ref201","first-page":"20","article-title":"A modification of the phenol-alcohol technique for toenail correction","volume":"13","author":"Greene","year":"1964","journal-title":"Curr Podiatry"},{"key":"ref171","author":"Laco","year":"1990","journal-title":"Operative Care of Nail Disorders: Principles and Practice of Podiatric Medicine"},{"key":"ref21","author":"Laco","year":"1990","journal-title":"Operative Care of Nail Disorders: Principles and Practice of Podiatric Medicine"},{"key":"ref11","first-page":"233","article-title":"The phenol-alcohol technique for toenails excision","volume":"5","author":"Nyman","year":"1956","journal-title":"J Chirop Soc"},{"key":"ref251","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1097\/01.ASW.0000391187.89587.2f","article-title":"Evaluating antimicrobial efficacy and cost of 3 dressings containing silver versus a novel antimicrobial hydrogel 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