{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T13:16:59Z","timestamp":1783430219426,"version":"3.54.6"},"reference-count":13,"publisher":"MDPI AG","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAPMA"],"published-print":{"date-parts":[[2002,7]]},"abstract":"<jats:p>Charcot\u2019s arthropathy is a devastating condition affecting diabetic patients with peripheral neuropathy, resulting in a foot at risk for ulceration and amputation. Early diagnosis is important for the institution of appropriate treatment, which may help prevent disease progression and foot deformity. This article discusses the pathogenesis and treatment options available for the disorder. (J Am Podiatr Med Assoc 92(7): 381-383, 2002)<\/jats:p>","DOI":"10.7547\/87507315-92-7-381","type":"journal-article","created":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T10:51:29Z","timestamp":1396349489000},"page":"381-383","source":"Crossref","is-referenced-by-count":14,"title":["Medical Treatment of Charcot\u2019s Arthropathy"],"prefix":"10.3390","volume":"92","author":[{"given":"Edward B.","family":"Jude","sequence":"first","affiliation":[{"name":"Consultant Physician, Diabetes Centre, Tameside General Hospital, Fountain St, Ashton-Under-Lyne, Lancashire OL6 9RW, England."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J. M.","family":"Boulton","sequence":"additional","affiliation":[{"name":"Professor, Department of Medicine, Manchester Royal Infirmary, Manchester, England."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","reference":[{"key":"R1","series-title":"Diabetes Care","first-page":"201","volume":"17","year":"1994","unstructured":"Cavanagh PR, Young MJ, Adams JE, et al: Radiographic abnormalities in the feet of patients with diabetic neuropathy. .Diabetes Care17::201. ,1994. .8174448"},{"key":"R2","series-title":"Foot","first-page":"65","volume":"5","year":"1995","unstructured":"Shaw JE, Boulton AJM: The Charcot foot. .Foot5::65. ,1995. ."},{"key":"R3","series-title":"Diabetes Care","first-page":"34","volume":"18","year":"1995","unstructured":"Young MJ, Marshall A, Adams JE, et al: Osteopenia, neurological dysfunction, and the development of Charcot neuroarthropathy. .Diabetes Care18::34. ,1995. .7698045"},{"key":"R4","series-title":"Diabet Med","first-page":"P26","volume":"11","year":"1994","unstructured":"Rawesh A, Foster A, Barrett J, et al: A fall in bone mineral density of the foot predicts the development of Charcot foot [abstract]. .Diabet Med11: (suppl 1):P26. ,1994. ."},{"key":"R5","series-title":"Q J Med","first-page":"843","volume":"57","year":"1985","unstructured":"Edmonds ME, Clarke MB, Newton S, et al: Increased uptake of bone radiopharmaceutical in diabetic neuropathy. .Q J Med57::843. ,1985. .4095254"},{"key":"R6","series-title":"Diabet Med","first-page":"527","volume":"14","year":"1997","unstructured":"Gough A, Abraha H, Li F, et al: Measurement of markers of osteoclast and osteoblastic activity in patients with acute and chronic diabetic Charcot neuroarthropathy. .Diabet Med14::527. ,1997. .9223389"},{"key":"R7","series-title":"Diabetologia","first-page":"A275","volume":"41","year":"1998","unstructured":"Selby PL, Jude EB, Burgess J, et al: Bone turnover markers in acute Charcot neuroarthropathy. .Diabetologia41: (suppl 1):A275. ,1998. ."},{"key":"R8","series-title":"Diabet Med","first-page":"357","volume":"14","year":"1997","unstructured":"Armstrong DG, Todd WF, Lavery LA, et al: The natural history of acute Charcot\u2019s arthropathy in a diabetic foot specialty clinic. .Diabet Med14::357. ,1997. .9171250"},{"key":"R9","series-title":"Clin Orthop","first-page":"58","volume":"296","year":"1993","unstructured":"Morgan JM, Biehl WC 3rd, Wagner FW Jr: Management of neuropathic arthropathy with the Charcot Restraint Orthotic Walker. .Clin Orthop296::58. ,1993. ."},{"key":"R10","series-title":"Foot","first-page":"158","volume":"8","year":"1998","unstructured":"McCrory JL, Morag E, Norkitis AJ, et al: Healing of Charcot fractures: skin temperature and radiographic correlates. .Foot8::158. ,1998. ."},{"key":"R11","series-title":"Pract Diabetes","first-page":"154","volume":"14","year":"1997","unstructured":"Chantelau E, Schnable T: Palliative radiotherapy for acute osteoarthropathy of diabetic feet: a preliminary study. .Pract Diabetes14::154. ,1997. ."},{"key":"R12","series-title":"Diabet Med","first-page":"14","volume":"11","year":"1994","unstructured":"Selby PL, Young MJ, Adams JE, et al: Bisphosphonate: a new treatment for diabetic Charcot neuroarthropathy. .Diabet Med11::14. ,1994. ."},{"key":"R13","series-title":"Diabetologia","first-page":"2032","volume":"44","year":"2001","unstructured":"Jude EB, Selby PL, Burgess J, et al: Bisphosphonates in the treatment of Charcot neuroarthropathy: a double-blind randomised controlled trial. .Diabetologia44::2032. ,2001. .11719835"}],"container-title":["Journal of the American Podiatric Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/japmaonline.org\/view\/journals\/apms\/92\/7\/87507315-92-7-381.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/japma\/article-pdf\/92\/7\/381\/1414769\/87507315-92-7-381.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/japmaonline.org\/downloadpdf\/journals\/apms\/92\/7\/87507315-92-7-381.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/japmaonline.org\/downloadpdf\/journals\/apms\/92\/7\/87507315-92-7-381.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T12:45:21Z","timestamp":1783428321000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1930-8264\/92\/7\/381"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,7]]},"references-count":13,"journal-issue":{"issue":"7"},"URL":"https:\/\/doi.org\/10.7547\/87507315-92-7-381","relation":{},"ISSN":["8750-7315","1930-8264"],"issn-type":[{"value":"8750-7315","type":"print"},{"value":"1930-8264","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,7]]}}}