{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T18:32:46Z","timestamp":1760985166310,"version":"3.41.2"},"reference-count":14,"publisher":"eLife Sciences Publications, Ltd","license":[{"start":{"date-parts":[[2014,8,15]],"date-time":"2014-08-15T00:00:00Z","timestamp":1408060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2014,8,15]],"date-time":"2014-08-15T00:00:00Z","timestamp":1408060800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2014,8,15]],"date-time":"2014-08-15T00:00:00Z","timestamp":1408060800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2014,8,15]],"date-time":"2014-08-15T00:00:00Z","timestamp":1408060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2014,8,15]],"date-time":"2014-08-15T00:00:00Z","timestamp":1408060800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2014,8,15]],"date-time":"2014-08-15T00:00:00Z","timestamp":1408060800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.elifesciences.org"],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>The primary role of the ZIP13 metal transporter in flies is to move iron ions out of cells, rather than moving zinc ions into cells, as is the case in human cells.<\/jats:p>","DOI":"10.7554\/elife.03997","type":"journal-article","created":{"date-parts":[[2014,8,14]],"date-time":"2014-08-14T13:18:55Z","timestamp":1408022335000},"source":"Crossref","is-referenced-by-count":5,"title":["Pumping iron"],"prefix":"10.7554","volume":"3","author":[{"given":"Caroline C","family":"Philpott","sequence":"first","affiliation":[{"name":"National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4374","published-online":{"date-parts":[[2014,8,15]]},"reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"40255","DOI":"10.1074\/jbc.M111.256784","article-title":"Biochemical characterization of human ZIP13 protein: a homo-dimerized zinc transporter involved in the spondylocheiro dysplastic Ehlers-Danlos syndrome","volume":"286","author":"Bin","year":"2011","journal-title":"Journal of Biological Chemistry"},{"key":"bib2","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/B978-0-12-394390-3.00009-4","article-title":"The cation selectivity of the ZIP transporters","volume":"69","author":"Dempski","year":"2012","journal-title":"Current Topics in Membranes"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"5624","DOI":"10.1073\/pnas.93.11.5624","article-title":"A novel iron-regulated metal transporter from plants identified by functional expression in yeast","volume":"93","author":"Eide","year":"1996","journal-title":"Proceedings of the National Academy of Sciences of the USA"},{"key":"bib4","doi-asserted-by":"publisher","first-page":"1290","DOI":"10.1016\/j.ajhg.2008.05.001","article-title":"Spondylocheiro dysplastic form of the Ehlers-Danlos syndrome\u2013an autosomal-recessive entity caused by mutations in the zinc transporter gene SLC39A13","volume":"82","author":"Giunta","year":"2008","journal-title":"American Journal of Human Genetics"},{"key":"bib5","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1016\/j.mam.2012.05.011","article-title":"The SLC39 family of zinc transporters","volume":"34","author":"Jeong","year":"2013","journal-title":"Molecular Aspects of Medicine"},{"key":"bib6","doi-asserted-by":"publisher","first-page":"E3530","DOI":"10.1073\/pnas.1211775110","article-title":"Promotion of vesicular zinc efflux by ZIP13 and its implications for spondylocheiro dysplastic Ehlers-Danlos syndrome","volume":"109","author":"Jeong","year":"2012","journal-title":"Proceedings of the National Academy of Sciences of the USA"},{"key":"bib7","doi-asserted-by":"publisher","first-page":"22566","DOI":"10.1074\/jbc.M604730200","article-title":"YKE4 (YIL023C) encodes a bidirectional zinc transporter in the endoplasmic reticulum of Saccharomyces cerevisiae","volume":"281","author":"Kumanovics","year":"2006","journal-title":"Journal of Biological Chemistry"},{"key":"bib8","doi-asserted-by":"publisher","first-page":"3254","DOI":"10.1242\/jeb.069260","article-title":"Systematic functional characterization of putative zinc transport genes and identification of zinc toxicosis phenotypes in Drosophila melanogaster","volume":"215","author":"Lye","year":"2012","journal-title":"Journal of Experimental Biology"},{"key":"bib9","doi-asserted-by":"publisher","first-page":"1622","DOI":"10.3390\/nu5051622","article-title":"Iron absorption in Drosophila melanogaster","volume":"5","author":"Mandilaras","year":"2013","journal-title":"Nutrients"},{"key":"bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/MMBR.62.1.1-34.1998","article-title":"Major facilitator superfamily","volume":"62","author":"Pao","year":"1998","journal-title":"Microbiology and Molecular Biology Reviews"},{"key":"bib11","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1038\/nrm2646","article-title":"ABC transporters: the power to change","volume":"10","author":"Rees","year":"2009","journal-title":"Nature Reviews Molecular Cell Biology"},{"key":"bib12","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1007\/s00425-009-0904-8","article-title":"Arabidopsis IRT2 cooperates with the high-affinity iron uptake system to maintain iron homeostasis in root epidermal cells","volume":"229","author":"Vert","year":"2009","journal-title":"Planta"},{"key":"bib13","doi-asserted-by":"publisher","first-page":"e03191","DOI":"10.7554\/eLife.03191","article-title":"The metal transporter ZIP13 supplies iron into the secretory pathway in Drosophila melanogaster","volume":"3","author":"Xiao","year":"2014","journal-title":"eLife"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"2454","DOI":"10.1073\/pnas.93.6.2454","article-title":"The yeast ZRT1 gene encodes the zinc transporter protein of a high-affinity uptake system induced by zinc limitation","volume":"93","author":"Zhao","year":"1996","journal-title":"Proceedings of the National Academy of Sciences of the USA"}],"container-title":["eLife"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/cdn.elifesciences.org\/articles\/03997\/elife-03997-v1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/cdn.elifesciences.org\/articles\/03997\/elife-03997-v1.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/elifesciences.org\/articles\/03997","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T00:47:51Z","timestamp":1697071671000},"score":1,"resource":{"primary":{"URL":"https:\/\/elifesciences.org\/articles\/03997"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8,15]]},"references-count":14,"alternative-id":["10.7554\/eLife.03997"],"URL":"https:\/\/doi.org\/10.7554\/elife.03997","archive":["CLOCKSS"],"relation":{},"ISSN":["2050-084X"],"issn-type":[{"type":"electronic","value":"2050-084X"}],"subject":[],"published":{"date-parts":[[2014,8,15]]},"assertion":[{"value":"2014-08-15","order":0,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e03997"}}