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Salient audiovisual cues paired with rewarding outcomes, such as the jackpot sound on a win, can enhance disadvantageous, risky choice in both rats and humans, yet it is unclear which aspects of the cue-reward contingencies drive this effect. Here, we implemented six variants of the rat gambling task (rGT), in which animals can maximize their total sugar pellet profits by avoiding options paired with higher per-trial gains but disproportionately longer and more frequent time-out penalties. When audiovisual cues were delivered concurrently with wins and scaled in salience with reward size, significantly more rats preferred the risky options as compared to the uncued rGT. Similar results were observed when the relationship between reward size and cue complexity was inverted and when cues were delivered concurrently with all outcomes. Conversely, risky choice did not increase when cues occurred randomly on 50% of trials, and decision making actually improved when cues were coincident with losses alone. As such, cues do not increase risky choice by simply elevating arousal or amplifying the difference between wins and losses. It is instead important that the cues are reliably associated with wins; presenting the cues on losing outcomes as well as wins does not diminish their ability to drive risky choice. Computational analyses indicate reductions in the impact of losses on decision making in all rGT variants in which win-paired cues increased risky choice. These results may help us understand how sensory stimulation can increase the addictive nature of gambling and gaming products.<\/jats:p>","DOI":"10.7554\/elife.105951","type":"journal-article","created":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T12:37:46Z","timestamp":1744115866000},"update-policy":"https:\/\/doi.org\/10.7554\/elife.105951","source":"Crossref","is-referenced-by-count":0,"title":["Audiovisual cues must be predictable and win-paired to drive risky choice"],"prefix":"10.7554","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1905-2199","authenticated-orcid":true,"given":"Brett A","family":"Hathaway","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03rmrcq20","id-type":"ROR","asserted-by":"publisher"}],"name":"Graduate Program in Neuroscience, Djavad Mowafaghian Centre for Brain Health, University of British Columbia","place":["Vancouver, Canada"]},{"name":"National Institute of Mental Health Intramural Research 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