{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:20:41Z","timestamp":1790745641470,"version":"4.1.0"},"reference-count":46,"publisher":"eLife Sciences Publications, Ltd","license":[{"start":{"date-parts":[[2016,11,14]],"date-time":"2016-11-14T00:00:00Z","timestamp":1479081600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2016,11,14]],"date-time":"2016-11-14T00:00:00Z","timestamp":1479081600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2016,11,14]],"date-time":"2016-11-14T00:00:00Z","timestamp":1479081600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007707","name":"University of California, Davis","doi-asserted-by":"publisher","award":["Behavioral Health Center of Excellence, Pilot Award"],"award-info":[{"award-number":["Behavioral Health Center of Excellence, Pilot Award"]}],"id":[{"id":"10.13039\/100007707","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Mental Health Services Act, Proposition 63","award":["Pilot Award"],"award-info":[{"award-number":["Pilot Award"]}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01MH065252"],"award-info":[{"award-number":["R01MH065252"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Categorization has been associated with distributed networks of the primate brain, including the prefrontal cortex (PFC) and posterior parietal cortex (PPC). Although category-selective spiking in PFC and PPC has been established, the frequency-dependent dynamic interactions of frontoparietal networks are largely unexplored. We trained monkeys to perform a delayed-match-to-spatial-category task while recording spikes and local field potentials from the PFC and PPC with multiple electrodes. We found category-selective beta- and delta-band synchrony between and within the areas. However, in addition to the categories, delta synchrony and spiking activity also reflected irrelevant stimulus dimensions. By contrast, beta synchrony only conveyed information about the task-relevant categories. Further, category-selective PFC neurons were synchronized with PPC beta oscillations, while neurons that carried irrelevant information were not. These results suggest that long-range beta-band synchrony could act as a filter that only supports neural representations of the variables relevant to the task at hand.<\/jats:p>","DOI":"10.7554\/elife.17822","type":"journal-article","created":{"date-parts":[[2016,11,14]],"date-time":"2016-11-14T08:00:09Z","timestamp":1479110409000},"source":"Crossref","is-referenced-by-count":101,"title":["Synchronous beta rhythms of frontoparietal networks support only behaviorally relevant representations"],"prefix":"10.7554","volume":"5","author":[{"given":"Evan G","family":"Antzoulatos","sequence":"first","affiliation":[{"name":"The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, United States"},{"name":"Center for Neuroscience, Department of Neurobiology, Physiology and Behavior, University of California at Davis, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Earl K","family":"Miller","sequence":"additional","affiliation":[{"name":"The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4374","published-online":{"date-parts":[[2016,11,14]]},"reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1016\/j.neuron.2009.08.028","article-title":"Intention, action planning, and decision making in parietal-frontal circuits","volume":"63","author":"Andersen","year":"2009","journal-title":"Neuron"},{"key":"bib2","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.neuron.2014.05.005","article-title":"Increases in functional connectivity between prefrontal cortex and striatum during category learning","volume":"83","author":"Antzoulatos","year":"2014","journal-title":"Neuron"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/j.neuron.2011.05.040","article-title":"Differences between neural activity in prefrontal cortex and striatum during learning of novel abstract categories","volume":"71","author":"Antzoulatos","year":"2011","journal-title":"Neuron"},{"key":"bib4","doi-asserted-by":"publisher","first-page":"10340","DOI":"10.1038\/ncomms10340","article-title":"Human brain networks function in connectome-specific harmonic waves","volume":"7","author":"Atasoy","year":"2016","journal-title":"Nature Communications"},{"key":"bib5","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1016\/j.neuron.2014.12.018","article-title":"Visual areas exert feedforward and feedback influences through distinct frequency channels","volume":"85","author":"Bastos","year":"2015","journal-title":"Neuron"},{"key":"bib6","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1016\/j.neuron.2012.06.037","article-title":"Attentional stimulus selection through selective synchronization between monkey visual areas","volume":"75","author":"Bosman","year":"2012","journal-title":"Neuron"},{"key":"bib7","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/j.neuroimage.2014.11.051","article-title":"Frontoparietal networks involved in categorization and item working memory","volume":"107","author":"Braunlich","year":"2015","journal-title":"NeuroImage"},{"key":"bib8","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1038\/nn.3954","article-title":"Frequency-specific hippocampal-prefrontal interactions during associative learning","volume":"18","author":"Brincat","year":"2015","journal-title":"Nature Neuroscience"},{"key":"bib9","doi-asserted-by":"publisher","first-page":"838","DOI":"10.1016\/j.neuron.2012.09.029","article-title":"Synchronous oscillatory neural ensembles for rules in the prefrontal cortex","volume":"76","author":"Buschman","year":"2012","journal-title":"Neuron"},{"key":"bib10","doi-asserted-by":"publisher","first-page":"1860","DOI":"10.1126\/science.1138071","article-title":"Top-down versus bottom-up control of attention in the prefrontal and posterior parietal cortices","volume":"315","author":"Buschman","year":"2007","journal-title":"Science"},{"key":"bib11","doi-asserted-by":"publisher","first-page":"11252","DOI":"10.1073\/pnas.1104666108","article-title":"Neural substrates of cognitive capacity limitations","volume":"108","author":"Buschman","year":"2011","journal-title":"PNAS"},{"key":"bib12","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1152\/jn.2000.83.3.1550","article-title":"Inactivation of parietal and prefrontal cortex reveals interdependence of neural activity during memory-guided saccades","volume":"83","author":"Chafee","year":"2000","journal-title":"Journal of Neurophysiology"},{"key":"bib13","doi-asserted-by":"crossref","first-page":"2919","DOI":"10.1152\/jn.1998.79.6.2919","article-title":"Matching patterns of activity in primate prefrontal area 8a and parietal area 7ip neurons during a spatial working memory task","volume":"79","author":"Chafee","year":"1998","journal-title":"Journal of Neurophysiology"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1016\/j.neuron.2010.05.005","article-title":"Representation of multiple, independent categories in the primate prefrontal cortex","volume":"66","author":"Cromer","year":"2010","journal-title":"Neuron"},{"key":"bib15","doi-asserted-by":"publisher","first-page":"1484","DOI":"10.1038\/nn.3509","article-title":"Prefrontal neurons transmit signals to parietal neurons that reflect executive control of cognition","volume":"16","author":"Crowe","year":"2013","journal-title":"Nature Neuroscience"},{"key":"bib16","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1016\/j.tics.2010.01.004","article-title":"The multiple-demand (MD) system of the primate brain: mental programs for intelligent behaviour","volume":"14","author":"Duncan","year":"2010","journal-title":"Trends in Cognitive Sciences"},{"key":"bib17","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1016\/j.conb.2010.02.015","article-title":"Beta-band oscillations--signalling the status quo?","volume":"20","author":"Engel","year":"2010","journal-title":"Current Opinion in Neurobiology"},{"key":"bib18","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1038\/35094565","article-title":"Dynamic predictions: oscillations and synchrony in top-down processing","volume":"2","author":"Engel","year":"2001","journal-title":"Nature Reviews Neuroscience"},{"key":"bib19","doi-asserted-by":"publisher","first-page":"16616","DOI":"10.1073\/pnas.1315235110","article-title":"Broad domain generality in focal regions of frontal and parietal cortex","volume":"110","author":"Fedorenko","year":"2013","journal-title":"PNAS"},{"key":"bib20","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1038\/nature05078","article-title":"Experience-dependent representation of visual categories in parietal cortex","volume":"443","author":"Freedman","year":"2006","journal-title":"Nature"},{"key":"bib21","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1126\/science.291.5502.312","article-title":"Categorical representation of visual stimuli in the primate prefrontal cortex","volume":"291","author":"Freedman","year":"2001","journal-title":"Science"},{"key":"bib22","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1016\/j.tics.2005.08.011","article-title":"A mechanism for cognitive dynamics: neuronal communication through neuronal coherence","volume":"9","author":"Fries","year":"2005","journal-title":"Trends in Cognitive Sciences"},{"key":"bib23","doi-asserted-by":"publisher","first-page":"3499","DOI":"10.1523\/JNEUROSCI.3585-11.2012","article-title":"Executive control over cognition: stronger and earlier rule-based modulation of spatial category signals in prefrontal cortex relative to parietal cortex","volume":"32","author":"Goodwin","year":"2012","journal-title":"Journal of Neuroscience"},{"key":"bib24","doi-asserted-by":"publisher","first-page":"10708","DOI":"10.1073\/pnas.1107297108","article-title":"Beta oscillations in the monkey sensorimotor network reflect somatosensory decision making","volume":"108","author":"Haegens","year":"2011","journal-title":"PNAS"},{"key":"bib25","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1017\/S0952523813000345","article-title":"Linking neural activity to complex decisions","volume":"30","author":"Hayden","year":"2013","journal-title":"Visual Neuroscience"},{"key":"bib26","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1016\/j.neuron.2009.11.018","article-title":"Flexibility of sensory representations in prefrontal cortex depends on cell type","volume":"64","author":"Hussar","year":"2009","journal-title":"Neuron"},{"key":"bib27","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1016\/j.neuron.2014.05.009","article-title":"Complementary roles for primate frontal and parietal cortex in guarding working memory from distractor stimuli","volume":"83","author":"Jacob","year":"2014","journal-title":"Neuron"},{"key":"bib28","doi-asserted-by":"publisher","first-page":"69","DOI":"10.3389\/fnsys.2011.00069","article-title":"Top-down spatial categorization signal from prefrontal to posterior parietal cortex in the primate","volume":"5","author":"Merchant","year":"2011","journal-title":"Frontiers in Systems Neuroscience"},{"key":"bib29","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/j.neuroimage.2015.06.043","article-title":"Inferior-frontal cortex phase synchronizes with the temporal-parietal junction prior to successful change detection","volume":"119","author":"Micheli","year":"2015","journal-title":"NeuroImage"},{"key":"bib30","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.conb.2012.11.011","article-title":"Cortical circuits for the control of attention","volume":"23","author":"Miller","year":"2013","journal-title":"Current Opinion in Neurobiology"},{"key":"bib31","doi-asserted-by":"crossref","first-page":"2580","DOI":"10.1152\/jn.2000.83.5.2580","article-title":"Selectivity for the shape, size, and orientation of objects for grasping in neurons of monkey parietal area AIP","volume":"83","author":"Murata","year":"2000","journal-title":"Journal of Neurophysiology"},{"key":"bib32","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2011\/156869","article-title":"FieldTrip: Open source software for advanced analysis of MEG, EEG, and invasive electrophysiological data","volume":"2011","author":"Oostenveld","year":"2011","journal-title":"Computational Intelligence and Neuroscience"},{"key":"bib33","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1016\/j.neuron.2013.01.007","article-title":"Independent category and spatial encoding in parietal cortex","volume":"77","author":"Rishel","year":"2013","journal-title":"Neuron"},{"key":"bib34","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1016\/j.neuropsychologia.2012.10.009","article-title":"Oscillatory activity during maintenance of spatial and temporal information in working memory","volume":"51","author":"Roberts","year":"2013","journal-title":"Neuropsychologia"},{"key":"bib35","doi-asserted-by":"publisher","first-page":"8519","DOI":"10.1523\/JNEUROSCI.4837-09.2010","article-title":"Prefrontal cortex activity during flexible categorization","volume":"30","author":"Roy","year":"2010","journal-title":"Journal of Neuroscience"},{"key":"bib36","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1126\/science.1224000","article-title":"Content-specific fronto-parietal synchronization during visual working memory","volume":"338","author":"Salazar","year":"2012","journal-title":"Science"},{"key":"bib37","doi-asserted-by":"publisher","first-page":"21341","DOI":"10.1073\/pnas.0908193106","article-title":"Phase-dependent neuronal coding of objects in short-term memory","volume":"106","author":"Siegel","year":"2009","journal-title":"PNAS"},{"key":"bib38","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1038\/nn.3016","article-title":"Preferential encoding of visual categories in parietal cortex compared with prefrontal cortex","volume":"15","author":"Swaminathan","year":"2012","journal-title":"Nature Neuroscience"},{"key":"bib39","doi-asserted-by":"publisher","first-page":"R658","DOI":"10.1016\/j.cub.2012.06.061","article-title":"The functional importance of rhythmic activity in the brain","volume":"22","author":"Thut","year":"2012","journal-title":"Current Biology"},{"key":"bib40","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1175\/1520-0477(1998)079<0061:APGTWA>2.0.CO;2","article-title":"A practical guide to wavelet analysis","volume":"79","author":"Torrence","year":"1998","journal-title":"Bulletin of the American Meteorological Society"},{"key":"bib41","doi-asserted-by":"publisher","first-page":"3038","DOI":"10.1523\/JNEUROSCI.2063-15.2016","article-title":"Representation of functional category in the monkey prefrontal cortex and its rule-dependent use for behavioral selection","volume":"36","author":"Tsutsui","year":"2016","journal-title":"Journal of Neuroscience"},{"key":"bib42","doi-asserted-by":"publisher","first-page":"2984","DOI":"10.1152\/jn.90713.2008","article-title":"Contributions of primate prefrontal and posterior parietal cortices to length and numerosity representation","volume":"101","author":"Tudusciuc","year":"2009","journal-title":"Journal of Neurophysiology"},{"key":"bib43","doi-asserted-by":"publisher","first-page":"17","DOI":"10.3389\/neuro.07.017.2009","article-title":"Neural synchrony in cortical networks: history, concept and current status","volume":"3","author":"Uhlhaas","year":"2009","journal-title":"Frontiers in Integrative Neuroscience"},{"key":"bib44","doi-asserted-by":"publisher","first-page":"6621","DOI":"10.1523\/JNEUROSCI.5071-11.2012","article-title":"Numerical rule coding in the prefrontal, premotor, and posterior parietal cortices of macaques","volume":"32","author":"Vallentin","year":"2012","journal-title":"Journal of Neuroscience"},{"key":"bib45","doi-asserted-by":"publisher","first-page":"1104","DOI":"10.1162\/jocn_a_00773","article-title":"Choice-related activity in the anterior intraparietal area during 3-D structure categorization","volume":"27","author":"Verhoef","year":"2015","journal-title":"Journal of Cognitive Neuroscience"},{"key":"bib46","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/j.neuroimage.2010.01.073","article-title":"The pairwise phase consistency: A bias-free measure of rhythmic neuronal synchronization","volume":"51","author":"Vinck","year":"2010","journal-title":"NeuroImage"}],"container-title":["eLife"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/cdn.elifesciences.org\/articles\/17822\/elife-17822-v3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/cdn.elifesciences.org\/articles\/17822\/elife-17822-v3.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/elifesciences.org\/articles\/17822","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T20:54:30Z","timestamp":1697057670000},"score":1,"resource":{"primary":{"URL":"https:\/\/elifesciences.org\/articles\/17822"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,14]]},"references-count":46,"alternative-id":["10.7554\/eLife.17822"],"URL":"https:\/\/doi.org\/10.7554\/elife.17822","archive":["CLOCKSS"],"relation":{"has-review":[{"id-type":"doi","id":"10.7554\/eLife.17822.030","asserted-by":"object"},{"id-type":"doi","id":"10.7554\/eLife.17822.029","asserted-by":"object"}]},"ISSN":["2050-084X"],"issn-type":[{"value":"2050-084X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,14]]},"article-number":"e17822"}}