{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T17:05:35Z","timestamp":1790010335728,"version":"4.0.1"},"reference-count":46,"publisher":"eLife Sciences Publications, Ltd","license":[{"start":{"date-parts":[[2017,10,20]],"date-time":"2017-10-20T00:00:00Z","timestamp":1508457600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2017,10,20]],"date-time":"2017-10-20T00:00:00Z","timestamp":1508457600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2017,10,20]],"date-time":"2017-10-20T00:00:00Z","timestamp":1508457600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["MOP-53339"],"award-info":[{"award-number":["MOP-53339"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000156","name":"Fonds de Recherche du Qu\u00e9bec - Sant\u00e9","doi-asserted-by":"publisher","award":["Infrastructure Group Grant"],"award-info":[{"award-number":["Infrastructure Group Grant"]}],"id":[{"id":"10.13039\/501100000156","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>We test the hypothesis that the posterior parietal cortex (PPC) contributes to the control of visually guided locomotor gait modifications by constructing an estimation of object location relative to body state, and in particular the changing gap between them. To test this hypothesis, we recorded neuronal activity from areas 5b and 7 of the PPC of cats walking on a treadmill and stepping over a moving obstacle whose speed of advance was varied (slowed or accelerated with respect to the speed of the cat). We found distinct populations of neurons in the PPC, primarily in area 5b, that signaled distance- or time-to-contact with the obstacle, regardless of which limb was the first to step over the obstacle. We propose that these cells are involved in a sensorimotor transformation whereby information on the location of an obstacle with respect to the body is used to initiate the gait modification.<\/jats:p>","DOI":"10.7554\/elife.28143","type":"journal-article","created":{"date-parts":[[2017,10,19]],"date-time":"2017-10-19T10:00:09Z","timestamp":1508407209000},"source":"Crossref","is-referenced-by-count":59,"title":["Posterior parietal cortex estimates the relationship between object and body location during locomotion"],"prefix":"10.7554","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6610-9058","authenticated-orcid":true,"given":"Daniel S","family":"Marigold","sequence":"first","affiliation":[{"name":"Department of Biomedical Physiology and Kinesiology, Simon Fraser University, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5199-3581","authenticated-orcid":true,"given":"Trevor","family":"Drew","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Neurosciences, Universit\u00e9 de Montr\u00e9al, Qu\u00e9bec, Canada"},{"name":"Groupe de Recherche sur le Syst\u00e8me Nerveux Central, Universit\u00e9 de Montr\u00e9al, Qu\u00e9bec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4374","published-online":{"date-parts":[[2017,10,20]]},"reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1152\/jn.00912.2009","article-title":"A contribution of area 5 of the posterior parietal cortex to the planning of visually guided locomotion: limb-specific and limb-independent effects","volume":"103","author":"Andujar","year":"2010","journal-title":"Journal of Neurophysiology"},{"key":"bib2","doi-asserted-by":"publisher","first-page":"18686","DOI":"10.1073\/pnas.1314311110","article-title":"A universal strategy for visually guided landing","volume":"110","author":"Baird","year":"2013","journal-title":"PNAS"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1152\/jn.00011.2012","article-title":"Effector selection precedes reach planning in the dorsal parietofrontal cortex","volume":"108","author":"Bernier","year":"2012","journal-title":"Journal of Neurophysiology"},{"key":"bib4","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1016\/j.nlm.2008.09.015","article-title":"Where am I and how will I get there from here? 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