{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T10:12:49Z","timestamp":1790071969530,"version":"4.0.1"},"reference-count":67,"publisher":"eLife Sciences Publications, Ltd","license":[{"start":{"date-parts":[[2018,2,20]],"date-time":"2018-02-20T00:00:00Z","timestamp":1519084800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2018,2,20]],"date-time":"2018-02-20T00:00:00Z","timestamp":1519084800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2018,2,20]],"date-time":"2018-02-20T00:00:00Z","timestamp":1519084800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Recent work has estimated that sub-Saharan Africa could lose US$3.5 billion of economic productivity every year as a result of schistosomiasis and soil-transmitted helminthiasis. One of the main interventions to control schistosomiasis is the provision of safe water to limit the contact with infected water bodies and break the cycle of transmission. To date, a rigorous quantification of the impact of safe water supplies on schistosomiasis is lacking. Using data from one of Africa\u2019s largest population-based cohorts, we establish the impact of the scale-up of piped water in a typical rural South African population over a seven-year time horizon. High coverage of piped water in the community decreased a child\u2019s risk of urogenital schistosomiasis infection eight-fold (adjusted odds ratio = 0.12, 95% CI 0.06\u20130.26, p&lt;0.001). The provision of safe water could drive levels of urogenital schistosomiasis infection to low levels of endemicity in rural African settings.<\/jats:p>","DOI":"10.7554\/elife.33065","type":"journal-article","created":{"date-parts":[[2018,2,20]],"date-time":"2018-02-20T05:05:08Z","timestamp":1519103108000},"source":"Crossref","is-referenced-by-count":21,"title":["Impact of the scale-up of piped water on urogenital schistosomiasis infection in rural South Africa"],"prefix":"10.7554","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9797-0000","authenticated-orcid":true,"given":"Frank","family":"Tanser","sequence":"first","affiliation":[{"name":"Africa Health Research Institute, KwaZulu-Natal, South Africa"},{"name":"School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa"},{"name":"Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa"},{"name":"Institute of Epidemiology and Health Care, University College London, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel K","family":"Azongo","sequence":"additional","affiliation":[{"name":"Navrongo Health Research Centre, Ghana Health Service, Navrongo, Upper East Region, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5742-0511","authenticated-orcid":true,"given":"Alain","family":"Vandormael","sequence":"additional","affiliation":[{"name":"Africa Health Research Institute, KwaZulu-Natal, South Africa"},{"name":"School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa"},{"name":"KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Till","family":"B\u00e4rnighausen","sequence":"additional","affiliation":[{"name":"Africa Health Research Institute, KwaZulu-Natal, South Africa"},{"name":"Institute of Epidemiology and Health Care, University College London, London, United Kingdom"},{"name":"Department of Global Health and Population, Harvard T.H. 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