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We aimed to disentangle three possible functions of the rTPJ for human altruism, namely: implementing the motivation to help, signaling conflicts between moral and material values, or representing social reputation concerns. Our novel donation-decision task consisted of decisions requiring trade-offs of either positive moral values and monetary cost when donating to a good cause, or negative moral values and monetary benefits when sending money to a bad cause. Disrupting the rTPJ using transcranial magnetic stimulation did not change the general motivation to give or to react to social reputation cues, but specifically reduced the behavioral impact of moral-material conflicts. These findings reveal that signaling moral-material conflict is a core rTPJ mechanism that may contribute to a variety of human moral behaviors.<\/jats:p>","DOI":"10.7554\/elife.40671","type":"journal-article","created":{"date-parts":[[2018,12,18]],"date-time":"2018-12-18T10:11:44Z","timestamp":1545127904000},"source":"Crossref","is-referenced-by-count":51,"title":["A causal role for right temporo-parietal junction in signaling moral conflict"],"prefix":"10.7554","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8783-7281","authenticated-orcid":true,"given":"Ignacio","family":"Obeso","sequence":"first","affiliation":[{"name":"Neuroeconomics, reward and decision making group, Institut des Sciences Cognitives Marc Jeannerod, CNRS, UMR 5229 and Universit\u00e9 Claude Bernard (UCBL), Lyon 1, Bron, France"},{"name":"Fundaci\u00f3n de Investigaci\u00f3n HM Hospitales, HM Hospitales \u2013 Centro Integral en Neurociencias HM CINAC, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9789-3383","authenticated-orcid":true,"given":"Marius","family":"Moisa","sequence":"additional","affiliation":[{"name":"Laboratory for Social and Neural Systems Research, Department of Economics, University of Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3964-2364","authenticated-orcid":true,"given":"Christian C","family":"Ruff","sequence":"additional","affiliation":[{"name":"Laboratory for Social and Neural Systems Research, Department of Economics, University of Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2157-1529","authenticated-orcid":true,"given":"Jean-Claude","family":"Dreher","sequence":"additional","affiliation":[{"name":"Neuroeconomics, reward and decision making group, Institut des Sciences Cognitives Marc Jeannerod, CNRS, UMR 5229 and Universit\u00e9 Claude Bernard (UCBL), Lyon 1, Bron, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4374","published-online":{"date-parts":[[2018,12,18]]},"reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1257\/aer.99.1.544","article-title":"Doing good or doing well? 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