{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T00:58:16Z","timestamp":1784595496011,"version":"3.55.0"},"reference-count":62,"publisher":"eLife Sciences Publications, Ltd","license":[{"start":{"date-parts":[[2020,3,24]],"date-time":"2020-03-24T00:00:00Z","timestamp":1585008000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,3,24]],"date-time":"2020-03-24T00:00:00Z","timestamp":1585008000000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,3,24]],"date-time":"2020-03-24T00:00:00Z","timestamp":1585008000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31872920 and 31571978"],"award-info":[{"award-number":["31872920 and 31571978"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31571978"],"award-info":[{"award-number":["31571978"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Carbon catabolite repression 4 (CCR4) is a conserved mRNA deadenylase regulating posttranscriptional gene expression. However, regulation of CCR4 in virus infections is less understood. Here, we characterized a pro-viral role of CCR4 in replication of a plant cytorhabdovirus, Barley yellow striate mosaic virus (BYSMV). The barley (Hordeum vulgare) CCR4 protein (HvCCR4) was identified to interact with the BYSMV phosphoprotein (P). The BYSMV P protein recruited HvCCR4 from processing bodies (PBs) into viroplasm-like bodies. Overexpression of HvCCR4 promoted BYSMV replication in plants. Conversely, knockdown of the small brown planthopper CCR4 inhibited viral accumulation in the insect vector. Biochemistry experiments revealed that HvCCR4 was recruited into N\u2013RNA complexes by the BYSMV P protein and triggered turnover of N-bound cellular mRNAs, thereby releasing RNA-free N protein to bind viral genomic RNA for optimal viral replication. Our results demonstrate that the co-opted CCR4-mediated RNA decay facilitates cytorhabdovirus replication in plants and insects.<\/jats:p>","DOI":"10.7554\/elife.53753","type":"journal-article","created":{"date-parts":[[2020,3,24]],"date-time":"2020-03-24T09:00:20Z","timestamp":1585040420000},"source":"Crossref","is-referenced-by-count":23,"title":["CCR4, a RNA decay factor, is hijacked by a plant cytorhabdovirus phosphoprotein to facilitate virus replication"],"prefix":"10.7554","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0473-2738","authenticated-orcid":true,"given":"Zhen-Jia","family":"Zhang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Agro-Biotechnology, College of Biological Sciences, China Agricultural University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Gao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agro-Biotechnology, College of Biological Sciences, China Agricultural University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Dong","family":"Fang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agro-Biotechnology, College of Biological Sciences, China Agricultural University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Hang","family":"Ding","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agro-Biotechnology, College of Biological Sciences, China Agricultural University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Min","family":"Gao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agro-Biotechnology, College of Biological Sciences, China Agricultural University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Ya","family":"Xu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agro-Biotechnology, College of Biological Sciences, China Agricultural University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Cao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agro-Biotechnology, College of Biological Sciences, China Agricultural University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Hui","family":"Qiao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agro-Biotechnology, College of Biological Sciences, China Agricultural University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Zhou","family":"Yang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agro-Biotechnology, College of Biological Sciences, China Agricultural University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenggui","family":"Han","sequence":"additional","affiliation":[{"name":"College of Plant Protection, China Agricultural University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Plant Protection, China Agricultural University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuefeng","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Plant Pathology, College of Plant Protection, Shandong Agricultural University, Shandong Province Key Laboratory of Agricultural Microbiology, Tai'an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawei","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agro-Biotechnology, College of Biological Sciences, China Agricultural University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3082-2462","authenticated-orcid":true,"given":"Xian-Bing","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agro-Biotechnology, College of Biological Sciences, China Agricultural University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4374","published-online":{"date-parts":[[2020,3,24]]},"reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1146\/annurev.ento.54.110807.090454","article-title":"Cellular and molecular aspects of rhabdovirus interactions with insect and plant hosts","volume":"54","author":"Ammar","year":"2009","journal-title":"Annual Review of Entomology"},{"key":"bib2","doi-asserted-by":"publisher","first-page":"2015","DOI":"10.1093\/pcp\/pcz089","article-title":"Identification of Arabidopsis CCR4-NOT complexes with pumilio RNA-Binding proteins, APUM5 and APUM2","volume":"60","author":"Arae","year":"2019","journal-title":"Plant and Cell Physiology"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"13922","DOI":"10.1128\/JVI.01517-07","article-title":"DDX3 DEAD-box RNA helicase is required for hepatitis C virus RNA replication","volume":"81","author":"Ariumi","year":"2007","journal-title":"Journal of Virology"},{"key":"bib4","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/j.molcel.2012.08.014","article-title":"Architecture of the nuclease module of the yeast Ccr4-not complex: the Not1-Caf1-Ccr4 interaction","volume":"48","author":"Basquin","year":"2012","journal-title":"Molecular Cell"},{"key":"bib5","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1016\/j.chom.2008.03.004","article-title":"P bodies, stress granules, and viral life cycles","volume":"3","author":"Beckham","year":"2008","journal-title":"Cell Host & Microbe"},{"key":"bib6","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.01419","article-title":"Transmission characteristics of barley yellow striate mosaic virus in its planthopper vector Laodelphax striatellus","volume":"9","author":"Cao","year":"2018","journal-title":"Frontiers in Microbiology"},{"key":"bib7","doi-asserted-by":"publisher","first-page":"13478","DOI":"10.1128\/JVI.01244-07","article-title":"Interaction of vesicular stomatitis virus P and N proteins: identification of two overlapping domains at the N terminus of P that are involved in N0-P complex formation and encapsidation of viral genome RNA","volume":"81","author":"Chen","year":"2007","journal-title":"Journal of Virology"},{"key":"bib8","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1007\/978-1-4614-5107-5_11","article-title":"Deadenylation and P-bodies","volume":"768","author":"Chen","year":"2013","journal-title":"Advances in Experimental Medicine and Biology"},{"key":"bib9","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1007\/s11103-016-0548-6","article-title":"Novel interaction between CCR4 and CAF1 in rice CCR4-NOT deadenylase complex","volume":"93","author":"Chou","year":"2017","journal-title":"Plant Molecular Biology"},{"key":"bib10","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2011.00099","article-title":"RNA decay and RNA silencing in plants: competition or collaboration?","volume":"2","author":"Christie","year":"2011","journal-title":"Frontiers in Plant Science"},{"key":"bib11","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1002\/wrna.1332","article-title":"The Ccr4-Not complex is a key regulator of eukaryotic gene expression","volume":"7","author":"Collart","year":"2016","journal-title":"Wiley Interdisciplinary Reviews: RNA"},{"key":"bib12","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1104\/pp.103.027979","article-title":"A gateway cloning vector set for high-throughput functional analysis of genes in planta","volume":"133","author":"Curtis","year":"2003","journal-title":"Plant Physiology"},{"key":"bib13","doi-asserted-by":"publisher","DOI":"10.1094\/PDIS-06-14-0579-PDN","article-title":"First Report of Barley yellow striate mosaic virus on Wheat in China","volume":"98","author":"Di","year":"2014","journal-title":"Plant Disease"},{"key":"bib14","doi-asserted-by":"publisher","DOI":"10.3390\/v8110303","article-title":"Plant Virus-Insect Vector Interactions: Current and Potential Future Research Directions","volume":"8","author":"Dietzgen","year":"2016","journal-title":"Viruses"},{"key":"bib15","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1016\/S0968-0004(00)01582-6","article-title":"Functionally unrelated signalling proteins contain a fold similar to Mg2+-dependent endonucleases","volume":"25","author":"Dlaki\u0107","year":"2000","journal-title":"Trends in Biochemical Sciences"},{"key":"bib16","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1128\/JVI.01657-10","article-title":"Poliovirus-mediated disruption of cytoplasmic processing bodies","volume":"85","author":"Dougherty","year":"2011","journal-title":"Journal of Virology"},{"key":"bib17","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-2-9","article-title":"Identification of four families of yCCR4- and Mg2+-dependent endonuclease-related proteins in higher eukaryotes, and characterization of orthologs of yCCR4 with a conserved leucine-rich repeat essential for hCAF1\/hPOP2 binding","volume":"2","author":"Dupressoir","year":"2001","journal-title":"BMC Genomics"},{"key":"bib18","doi-asserted-by":"publisher","first-page":"4049","DOI":"10.1093\/jxb\/erz195","article-title":"A Cytorhabdovirus phosphoprotein forms mobile inclusions trafficked on the actin\/ER network for viral RNA synthesis","volume":"70","author":"Fang","year":"2019","journal-title":"Journal of Experimental Botany"},{"key":"bib19","doi-asserted-by":"publisher","first-page":"2120","DOI":"10.1111\/nph.15889","article-title":"Rescue of a plant Cytorhabdovirus as versatile expression platforms for planthopper and cereal genomic studies","volume":"223","author":"Gao","year":"2019","journal-title":"New Phytologist"},{"key":"bib20","doi-asserted-by":"publisher","first-page":"1588","DOI":"10.1111\/mpp.12851","article-title":"Host factors against plant viruses","volume":"20","author":"Garcia-Ruiz","year":"2019","journal-title":"Molecular Plant Pathology"},{"key":"bib21","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1038\/nrm2104","article-title":"The highways and byways of mRNA decay","volume":"8","author":"Garneau","year":"2007","journal-title":"Nature Reviews Molecular Cell Biology"},{"key":"bib22","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1046\/j.1365-313X.2002.01360.x","article-title":"pGD vectors: versatile tools for the expression of green and red fluorescent protein fusions in agroinfiltrated plant leaves","volume":"31","author":"Goodin","year":"2002","journal-title":"The Plant Journal"},{"key":"bib23","doi-asserted-by":"publisher","first-page":"211","DOI":"10.2217\/fvl-2017-0106","article-title":"Viral manipulation of host mRNA decay","volume":"13","author":"Guo","year":"2018","journal-title":"Future Virology"},{"key":"bib24","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.01695","article-title":"Recessive resistance to plant viruses: potential resistance genes beyond translation initiation factors","volume":"7","author":"Hashimoto","year":"2016","journal-title":"Frontiers in Microbiology"},{"key":"bib25","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1016\/j.cell.2009.01.019","article-title":"The many pathways of RNA degradation","volume":"136","author":"Houseley","year":"2009","journal-title":"Cell"},{"key":"bib26","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/j.virusres.2011.09.025","article-title":"Structural insights into the rhabdovirus transcription\/replication complex","volume":"162","author":"Ivanov","year":"2011","journal-title":"Virus Research"},{"key":"bib27","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1016\/j.virol.2009.01.015","article-title":"Silencing of Nicotiana benthamiana Xrn4p exoribonuclease promotes Tombusvirus RNA accumulation and recombination","volume":"386","author":"Jaag","year":"2009","journal-title":"Virology"},{"key":"bib28","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1104\/pp.17.00871","article-title":"Three-Dimensional analysis of chloroplast structures associated with virus infection","volume":"176","author":"Jin","year":"2018","journal-title":"Plant Physiology"},{"key":"bib29","doi-asserted-by":"publisher","first-page":"1261","DOI":"10.1016\/j.febslet.2009.03.055","article-title":"SGS3 and RDR6 interact and colocalize in cytoplasmic SGS3\/RDR6-bodies","volume":"583","author":"Kumakura","year":"2009","journal-title":"FEBS Letters"},{"key":"bib30","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1016\/j.cell.2013.04.016","article-title":"Roquin promotes constitutive mRNA decay via a conserved class of stem-loop recognition motifs","volume":"153","author":"Leppek","year":"2013","journal-title":"Cell"},{"key":"bib31","doi-asserted-by":"publisher","first-page":"465","DOI":"10.2217\/fvl.11.10","article-title":"Structure, interactions with host cell and functions of rhabdovirus phosphoprotein","volume":"6","author":"Leyrat","year":"2011","journal-title":"Future Virology"},{"key":"bib32","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002248","article-title":"Structure of the vesicular stomatitis virus N\u2070-P complex","volume":"7","author":"Leyrat","year":"2011","journal-title":"PLOS Pathogens"},{"key":"bib33","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007228","article-title":"RNA decay is an antiviral defense in plants that is counteracted by viral RNA silencing suppressors","volume":"14","author":"Li","year":"2018","journal-title":"PLOS Pathogens"},{"key":"bib34","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1002\/wrna.1162","article-title":"Regulation of stress granules and P-bodies during RNA virus infection","volume":"4","author":"Lloyd","year":"2013","journal-title":"Wiley Interdisciplinary Reviews: RNA"},{"key":"bib35","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1093\/jxb\/eru447","article-title":"Different roles for RNA silencing and RNA processing components in virus recovery and virus-induced gene silencing in plants","volume":"66","author":"Ma","year":"2015","journal-title":"Journal of Experimental Botany"},{"key":"bib36","doi-asserted-by":"publisher","first-page":"1889","DOI":"10.1007\/s00705-014-2029-z","article-title":"Plant rhabdoviruses: new insights and research needs in the interplay of negative-strand RNA viruses with plant and insect hosts","volume":"159","author":"Mann","year":"2014","journal-title":"Archives of Virology"},{"key":"bib37","doi-asserted-by":"publisher","first-page":"2658","DOI":"10.1128\/JVI.62.8.2658-2664.1988","article-title":"Complex formation with vesicular stomatitis virus phosphoprotein NS prevents binding of nucleocapsid protein N to nonspecific RNA","volume":"62","author":"Masters","year":"1988","journal-title":"Journal of Virology"},{"key":"bib38","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1016\/j.virol.2006.01.030","article-title":"Rabies virus chaperone: identification of the phosphoprotein peptide that keeps nucleoprotein soluble and free from non-specific RNA","volume":"349","author":"Mavrakis","year":"2006","journal-title":"Virology"},{"key":"bib39","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1038\/nri.2017.63","article-title":"Translation inhibition and stress granules in the antiviral immune response","volume":"17","author":"McCormick","year":"2017","journal-title":"Nature Reviews Immunology"},{"key":"bib40","doi-asserted-by":"publisher","first-page":"8224","DOI":"10.1093\/nar\/gkz509","article-title":"DEAD-box helicase eIF4A2 inhibits CNOT7 deadenylation activity","volume":"47","author":"Meijer","year":"2019","journal-title":"Nucleic Acids Research"},{"key":"bib41","doi-asserted-by":"publisher","first-page":"315","DOI":"10.3109\/10409238.2012.667214","article-title":"Ccr4-Not complex: the control freak of eukaryotic cells","volume":"47","author":"Miller","year":"2012","journal-title":"Critical Reviews in Biochemistry and Molecular Biology"},{"key":"bib42","doi-asserted-by":"publisher","first-page":"4699","DOI":"10.1093\/nar\/gkt152","article-title":"Cytoplasmic and nuclear quality control and turnover of single-stranded RNA modulate post-transcriptional gene silencing in plants","volume":"41","author":"Moreno","year":"2013","journal-title":"Nucleic Acids Research"},{"key":"bib43","doi-asserted-by":"publisher","first-page":"1550","DOI":"10.1261\/rna.057679.116","article-title":"CCR4 and CAF1 deadenylases have an intrinsic activity to remove the post-poly(A) sequence","volume":"22","author":"Niinuma","year":"2016","journal-title":"RNA"},{"key":"bib44","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1016\/j.molcel.2007.02.011","article-title":"P bodies and the control of mRNA translation and degradation","volume":"25","author":"Parker","year":"2007","journal-title":"Molecular Cell"},{"key":"bib45","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1016\/0042-6822(88)90477-1","article-title":"Viral proteins required for the in vitro replication of vesicular stomatitis virus defective interfering particle genome RNA","volume":"162","author":"Peluso","year":"1988","journal-title":"Virology"},{"key":"bib46","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/j.virol.2012.11.017","article-title":"Diversion of stress granules and P-bodies during viral infection","volume":"436","author":"Reineke","year":"2013","journal-title":"Virology"},{"key":"bib47","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1093\/pcp\/pcv012","article-title":"AtCCR4a and AtCCR4b are involved in determining the poly(A) Length of Granule-bound starch synthase 1 transcript and modulating sucrose and starch metabolism in Arabidopsis thaliana","volume":"56","author":"Suzuki","year":"2015","journal-title":"Plant and Cell Physiology"},{"key":"bib48","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1016\/j.bbagrm.2013.01.003","article-title":"RNA decay machines: deadenylation by the Ccr4\u2013Not and Pan2\u2013Pan3 complexes","volume":"1829","author":"Wahle","year":"2013","journal-title":"Biochimica Et Biophysica Acta (BBA) - Gene Regulatory Mechanisms"},{"key":"bib49","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.virusres.2011.09.004","article-title":"Rhabdovirus accessory genes","volume":"162","author":"Walker","year":"2011","journal-title":"Virus Research"},{"key":"bib50","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1111\/j.1365-313X.2004.02219.x","article-title":"Visualization of protein interactions in living plant cells using bimolecular fluorescence complementation","volume":"40","author":"Walter","year":"2004","journal-title":"The Plant Journal"},{"key":"bib51","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1146\/annurev-phyto-080614-120001","article-title":"Dissecting the molecular network of virus-plant interactions: the complex roles of host factors","volume":"53","author":"Wang","year":"2015","journal-title":"Annual Review of Phytopathology"},{"key":"bib52","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-22778-9","article-title":"Hsc70-2 is required for beet black scorch virus infection through interaction with replication and capsid proteins","volume":"8","author":"Wang","year":"2018","journal-title":"Scientific Reports"},{"key":"bib53","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.40670","article-title":"RNA-binding proteins distinguish between similar sequence motifs to promote targeted deadenylation by Ccr4-Not","volume":"8","author":"Webster","year":"2019","journal-title":"eLife"},{"key":"bib54","doi-asserted-by":"publisher","first-page":"1531","DOI":"10.1042\/BST0381531","article-title":"Cytoplasmic deadenylation: regulation of mRNA fate","volume":"38","author":"Wiederhold","year":"2010","journal-title":"Biochemical Society Transactions"},{"key":"bib55","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.pbi.2010.10.003","article-title":"Processing bodies and plant development","volume":"14","author":"Xu","year":"2011","journal-title":"Current Opinion in Plant Biology"},{"key":"bib56","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1038\/nature21690","article-title":"DND1 maintains germline stem cells via recruitment of the CCR4-NOT complex to target mRNAs","volume":"543","author":"Yamaji","year":"2017","journal-title":"Nature"},{"key":"bib57","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/j.virol.2014.12.042","article-title":"Characterization of the complete genome of barley yellow striate mosaic virus reveals a nested gene encoding a small hydrophobic protein","volume":"478","author":"Yan","year":"2015","journal-title":"Virology"},{"key":"bib58","doi-asserted-by":"publisher","first-page":"1582","DOI":"10.1105\/tpc.18.00122","article-title":"Barley stripe mosaic virus \u03b3b protein subverts autophagy to promote viral infection by disrupting the ATG7-ATG8 interaction","volume":"30","author":"Yang","year":"2018","journal-title":"The Plant Cell"},{"key":"bib59","doi-asserted-by":"publisher","first-page":"2194","DOI":"10.1016\/j.celrep.2019.07.054","article-title":"Orchestration of processing body dynamics and mRNA decay in Arabidopsis immunity","volume":"28","author":"Yu","year":"2019","journal-title":"Cell Reports"},{"key":"bib60","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006522","article-title":"Cucumber mosaic virus coat protein modulates the accumulation of 2b protein and antiviral silencing that causes symptom recovery in planta","volume":"13","author":"Zhang","year":"2017","journal-title":"PLOS Pathogens"},{"key":"bib61","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-06404-w","article-title":"LOTUS domain protein MARF1 binds CCR4-NOT deadenylase complex to post-transcriptionally regulate gene expression in oocytes","volume":"9","author":"Zhu","year":"2018","journal-title":"Nature Communications"},{"key":"bib62","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1093\/nar\/29.5.1017","article-title":"Exoribonuclease superfamilies: structural analysis and phylogenetic distribution","volume":"29","author":"Zuo","year":"2001","journal-title":"Nucleic Acids Research"}],"container-title":["eLife"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/cdn.elifesciences.org\/articles\/53753\/elife-53753-v2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/cdn.elifesciences.org\/articles\/53753\/elife-53753-v2.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/elifesciences.org\/articles\/53753","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T21:01:36Z","timestamp":1697058096000},"score":1,"resource":{"primary":{"URL":"https:\/\/elifesciences.org\/articles\/53753"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,24]]},"references-count":62,"alternative-id":["10.7554\/eLife.53753"],"URL":"https:\/\/doi.org\/10.7554\/elife.53753","archive":["CLOCKSS"],"relation":{"has-review":[{"id-type":"doi","id":"10.7554\/eLife.53753.sa2","asserted-by":"object"},{"id-type":"doi","id":"10.7554\/eLife.53753.sa1","asserted-by":"object"}]},"ISSN":["2050-084X"],"issn-type":[{"value":"2050-084X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,24]]},"article-number":"e53753"}}