{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T20:24:24Z","timestamp":1787948664075,"version":"build-2784847793"},"reference-count":134,"publisher":"eLife Sciences Publications, Ltd","license":[{"start":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T00:00:00Z","timestamp":1653955200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T00:00:00Z","timestamp":1653955200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T00:00:00Z","timestamp":1653955200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010663","name":"H2020 European Research Council","doi-asserted-by":"publisher","award":["ERC-2018-CoG-81904"],"award-info":[{"award-number":["ERC-2018-CoG-81904"]}],"id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["502961"],"award-info":[{"award-number":["502961"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000156","name":"Fonds de Recherche du Qu\u00e9bec - Sant\u00e9","doi-asserted-by":"publisher","award":["35510"],"award-info":[{"award-number":["35510"]}],"id":[{"id":"10.13039\/501100000156","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Max Planck Institute of Molecular Cell Biology and Genetics","award":["open access funding"],"award-info":[{"award-number":["open access funding"]}]},{"name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia Investigator grant","award":["CEECIND\/03268\/2018"],"award-info":[{"award-number":["CEECIND\/03268\/2018"]}]}],"content-domain":{"domain":["elifesciences.org"],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2022,5,30]]},"abstract":"<jats:p>Migration of cells in the developing brain is integral for the establishment of neural circuits and function of the central nervous system. While migration modes during which neurons employ predetermined directional guidance of either preexisting neuronal processes or underlying cells have been well explored, less is known about how cells featuring multipolar morphology migrate in the dense environment of the developing brain. To address this, we here investigated multipolar migration of horizontal cells in the zebrafish retina. We found that these cells feature several hallmarks of amoeboid-like migration that enable them to tailor their movements to the spatial constraints of the crowded retina. These hallmarks include cell and nuclear shape changes, as well as persistent rearward polarization of stable F-actin. Interference with the organization of the developing retina by changing nuclear properties or overall tissue architecture hampers efficient horizontal cell migration and layer formation showing that cell-tissue interplay is crucial for this process. In view of the high proportion of multipolar migration phenomena observed in brain development, the here uncovered amoeboid-like migration mode might be conserved in other areas of the developing nervous system.<\/jats:p>","DOI":"10.7554\/elife.76408","type":"journal-article","created":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T10:00:16Z","timestamp":1653991216000},"update-policy":"https:\/\/doi.org\/10.7554\/elife.76408","source":"Crossref","is-referenced-by-count":23,"title":["Amoeboid-like migration ensures correct horizontal cell layer formation in the developing vertebrate retina"],"prefix":"10.7554","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3974-5072","authenticated-orcid":true,"given":"Rana","family":"Amini","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05b8d3w18","id-type":"ROR","asserted-by":"publisher"}],"name":"Max Planck Institute of Molecular Cell Biology and Genetics","place":["Dresden, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Archit","family":"Bhatnagar","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05b8d3w18","id-type":"ROR","asserted-by":"publisher"}],"name":"Max Planck Institute of Molecular Cell Biology and Genetics","place":["Dresden, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3752-2382","authenticated-orcid":true,"given":"Raimund","family":"Schl\u00fc\u00dfler","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/042aqky30","id-type":"ROR","asserted-by":"publisher"}],"name":"Biotechnology Center, Center for Molecular and Cellular Bioengineering, Technische Universita\u0308t Dresden","place":["Dresden, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"M\u00f6llmert","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/042aqky30","id-type":"ROR","asserted-by":"publisher"}],"name":"Biotechnology Center, Center for Molecular and Cellular Bioengineering, Technische Universita\u0308t Dresden","place":["Dresden, Germany"]},{"id":[{"id":"https:\/\/ror.org\/020as7681","id-type":"ROR","asserted-by":"publisher"}],"name":"Max Planck Institute for the Science of Light and Max-Planck-Zentrum fu\u0308r Physik und Medizin","place":["Erlangen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jochen","family":"Guck","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/042aqky30","id-type":"ROR","asserted-by":"publisher"}],"name":"Biotechnology Center, Center for Molecular and Cellular Bioengineering, Technische Universita\u0308t Dresden","place":["Dresden, Germany"]},{"id":[{"id":"https:\/\/ror.org\/020as7681","id-type":"ROR","asserted-by":"publisher"}],"name":"Max Planck Institute for the Science of Light and Max-Planck-Zentrum fu\u0308r Physik und Medizin","place":["Erlangen, Germany"]},{"id":[{"id":"https:\/\/ror.org\/042aqky30","id-type":"ROR","asserted-by":"publisher"}],"name":"Physics of Life, Technische Universita\u0308t Dresden","place":["Dresden, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8835-1451","authenticated-orcid":true,"given":"Caren","family":"Norden","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05b8d3w18","id-type":"ROR","asserted-by":"publisher"}],"name":"Max Planck Institute of Molecular Cell Biology and Genetics","place":["Dresden, Germany"]},{"id":[{"id":"https:\/\/ror.org\/04b08hq31","id-type":"ROR","asserted-by":"publisher"}],"name":"Instituto Gulbenkian de Cie\u0302ncia, Rua da Quinta Grande 6","place":["Oeiras, Portugal"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4374","published-online":{"date-parts":[[2022,5,31]]},"reference":[{"key":"bib1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2017.00742","article-title":"Neuronal Migration and Lamination in the Vertebrate Retina","volume":"11","author":"Amini","year":"2017","journal-title":"Frontiers in Neuroscience"},{"key":"bib2","doi-asserted-by":"publisher","DOI":"10.1242\/dev.173450","article-title":"Stochastic single cell migration leads to robust horizontal cell layer formation in the vertebrate retina","volume":"146","author":"Amini","year":"2019","journal-title":"Development (Cambridge, England)"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1038\/192766b0","article-title":"Autoradiographic study of cell migration during histogenesis of cerebral cortex in the mouse","volume":"192","author":"Angevine","year":"1961","journal-title":"Nature"},{"key":"bib4","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.667213","article-title":"Endothelial Focal Adhesions Are Functional Obstacles for Leukocytes During Basolateral Crawling","volume":"12","author":"Arts","year":"2021","journal-title":"Frontiers in Immunology"},{"key":"bib5","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.cell.2006.12.021","article-title":"Trekking across the brain: the journey of neuronal migration","volume":"128","author":"Ayala","year":"2007","journal-title":"Cell"},{"key":"bib6","doi-asserted-by":"publisher","first-page":"3801","DOI":"10.1242\/jcs.206128","article-title":"Live imaging reveals distinct modes of neutrophil and macrophage migration within interstitial tissues","volume":"130","author":"Barros-Becker","year":"2017","journal-title":"Journal of Cell Science"},{"key":"bib7","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1080\/19490992.2014.1047714","article-title":"Comparative analysis of tools for live cell imaging of actin network architecture","volume":"4","author":"Belin","year":"2014","journal-title":"Bioarchitecture"},{"key":"bib8","doi-asserted-by":"publisher","first-page":"14434","DOI":"10.1073\/pnas.1207968109","article-title":"Cell mechanics control rapid transitions between blebs and lamellipodia during migration","volume":"109","author":"Bergert","year":"2012","journal-title":"PNAS"},{"key":"bib9","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1016\/j.modgep.2006.04.006","article-title":"GFAP transgenic zebrafish","volume":"6","author":"Bernardos","year":"2006","journal-title":"Gene Expression Patterns"},{"key":"bib10","first-page":"691","article-title":"The migration of neuroblasts in the developing cerebral cortex","volume":"99","author":"Berry","year":"1965","journal-title":"Journal of Anatomy"},{"key":"bib11","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2015.00363","article-title":"Microglia mechanics: immune activation alters traction forces and durotaxis","volume":"9","author":"Bollmann","year":"2015","journal-title":"Frontiers in Cellular Neuroscience"},{"key":"bib12","doi-asserted-by":"publisher","first-page":"1135","DOI":"10.1126\/science.176.4039.1135","article-title":"Age changes in the neuronal microenvironment","volume":"176","author":"Bondareff","year":"1972","journal-title":"Science (New York, N.Y.)"},{"key":"bib13","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/0014-4827(55)90055-0","article-title":"Mitosis in cultures of newt tissues. IV. The cell surface in late anaphase and the movements of ribonucleoprotein","volume":"8","author":"Boss","year":"1955","journal-title":"Experimental Cell Research"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"7939","DOI":"10.1073\/pnas.0702511104","article-title":"Endosomal recycling controls plasma membrane area during mitosis","volume":"104","author":"Boucrot","year":"2007","journal-title":"PNAS"},{"key":"bib15","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1007\/s004180050138","article-title":"A- and B-type lamins are differentially expressed in normal human tissues","volume":"107","author":"Broers","year":"1997","journal-title":"Histochemistry and Cell Biology"},{"key":"bib16","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1038\/nrm3488","article-title":"The nuclear lamins: flexibility in function","volume":"14","author":"Burke","year":"2013","journal-title":"Nature Reviews. Molecular Cell Biology"},{"key":"bib17","doi-asserted-by":"publisher","first-page":"822","DOI":"10.1002\/cm.20226","article-title":"Versatile fluorescent probes for actin filaments based on the actin-binding domain of utrophin","volume":"64","author":"Burkel","year":"2007","journal-title":"Cell Motility and the Cytoskeleton"},{"key":"bib18","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1038\/385450a0","article-title":"Traction forces of cytokinesis measured with optically modified elastic substrata","volume":"385","author":"Burton","year":"1997","journal-title":"Nature"},{"key":"bib19","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1083\/jcb.110.4.1067","article-title":"Chemoattractant-stimulated polymorphonuclear leukocytes contain two populations of actin filaments that differ in their spatial distributions and relative stabilities","volume":"110","author":"Cassimeris","year":"1990","journal-title":"The Journal of Cell Biology"},{"key":"bib20","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1038\/nrm2453","article-title":"Blebs lead the way: how to migrate without lamellipodia","volume":"9","author":"Charras","year":"2008","journal-title":"Nature Reviews. Molecular Cell Biology"},{"key":"bib21","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-05543-2","article-title":"Versatile functional roles of horizontal cells in the retinal circuit","volume":"7","author":"Chaya","year":"2017","journal-title":"Scientific Reports"},{"key":"bib22","doi-asserted-by":"publisher","first-page":"2665","DOI":"10.1242\/dev.122473","article-title":"Inhibitory neuron migration and IPL formation in the developing zebrafish retina","volume":"142","author":"Chow","year":"2015","journal-title":"Development (Cambridge, England)"},{"key":"bib23","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/0092-8674(79)90005-9","article-title":"Properties of a basement membrane-related glycoprotein synthesized in culture by a mouse embryonal carcinoma-derived cell line","volume":"16","author":"Chung","year":"1979","journal-title":"Cell"},{"key":"bib24","doi-asserted-by":"publisher","first-page":"3180","DOI":"10.1091\/mbc.E08-02-0225","article-title":"The PCH family member proline-serine-threonine phosphatase-interacting protein 1 targets to the leukocyte uropod and regulates directed cell migration","volume":"19","author":"Cooper","year":"2008","journal-title":"Molecular Biology of the Cell"},{"key":"bib25","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1083\/jcb.201305021","article-title":"Cell biology in neuroscience: mechanisms of cell migration in the nervous system","volume":"202","author":"Cooper","year":"2013","journal-title":"The Journal of Cell Biology"},{"key":"bib26","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2014.00386","article-title":"Molecules and mechanisms that regulate multipolar migration in the intermediate zone","volume":"8","author":"Cooper","year":"2014","journal-title":"Frontiers in Cellular Neuroscience"},{"key":"bib27","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2017.02.005","article-title":"Tmem2 Regulates Embryonic Vegf Signaling by Controlling Hyaluronic Acid Turnover","volume":"40","author":"De Angelis","year":"2017","journal-title":"Developmental Cell"},{"key":"bib28","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1038\/nmeth.2075","article-title":"Icy: an open bioimage informatics platform for extended reproducible research","volume":"9","author":"de Chaumont","year":"2012","journal-title":"Nature Methods"},{"key":"bib29","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1523\/JNEUROSCI.07-06-01928.1987","article-title":"Glial-guided granule neuron migration in vitro: a high-resolution time-lapse video microscopic study","volume":"7","author":"Edmondson","year":"1987","journal-title":"The Journal of Neuroscience"},{"key":"bib30","doi-asserted-by":"publisher","first-page":"1343","DOI":"10.1242\/dev.01018","article-title":"Newborn horizontal cells migrate bi-directionally across the neuroepithelium during retinal development","volume":"131","author":"Edqvist","year":"2004","journal-title":"Development (Cambridge, England)"},{"key":"bib31","doi-asserted-by":"publisher","first-page":"2670","DOI":"10.1364\/BOE.10.002670","article-title":"Brillouin Light Scattering Microspectroscopy for Biomedical Research and Applications: introduction to feature issue","volume":"10","author":"Elsayad","year":"2019","journal-title":"Biomedical Optics Express"},{"key":"bib32","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1016\/j.tcb.2019.04.002","article-title":"Probing Mechanical Properties in Biology Using Brillouin Microscopy","volume":"29","author":"Elsayad","year":"2019","journal-title":"Trends in Cell Biology"},{"key":"bib33","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1083\/jcb.114.5.967","article-title":"Microinjection of the catalytic fragment of myosin light chain kinase into dividing cells: effects on mitosis and cytokinesis","volume":"114","author":"Fishkind","year":"1991","journal-title":"The Journal of Cell Biology"},{"key":"bib34","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1002\/dneu.20946","article-title":"Extracellular matrix functions during neuronal migration and lamination in the mammalian central nervous system","volume":"71","author":"Franco","year":"2011","journal-title":"Developmental Neurobiology"},{"key":"bib35","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1083\/jcb.200909003","article-title":"Plasticity of cell migration: a multiscale tuning model","volume":"188","author":"Friedl","year":"2010","journal-title":"The Journal of Cell Biology"},{"key":"bib36","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.ceb.2010.10.015","article-title":"Nuclear mechanics during cell migration","volume":"23","author":"Friedl","year":"2011","journal-title":"Current Opinion in Cell Biology"},{"key":"bib37","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.26990","article-title":"Actin-based protrusions of migrating neutrophils are intrinsically lamellar and facilitate direction changes","volume":"6","author":"Fritz-Laylin","year":"2017","journal-title":"eLife"},{"key":"bib38","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/0165-3806(90)90220-s","article-title":"Neuron migration within the radial glial fiber system of the developing murine cerebrum: an electron microscopic autoradiographic analysis","volume":"52","author":"Gadisseux","year":"1990","journal-title":"Brain Research. Developmental Brain Research"},{"key":"bib39","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1016\/j.preteyeres.2008.02.001","article-title":"The genesis of retinal architecture: an emerging role for mechanical interactions?","volume":"27","author":"Galli-Resta","year":"2008","journal-title":"Progress in Retinal and Eye Research"},{"key":"bib40","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.jsb.2011.11.007","article-title":"Nuclear lamina at the crossroads of the cytoplasm and nucleus","volume":"177","author":"Gerace","year":"2012","journal-title":"Journal of Structural Biology"},{"key":"bib41","doi-asserted-by":"publisher","first-page":"2118","DOI":"10.1073\/pnas.71.5.2118","article-title":"Cyclic-AMP-controlled oscillations in suspended Dictyostelium cells: their relation to morphogenetic cell interactions","volume":"71","author":"Gerisch","year":"1974","journal-title":"PNAS"},{"key":"bib42","doi-asserted-by":"publisher","first-page":"14307","DOI":"10.1523\/JNEUROSCI.2198-15.2015","article-title":"Neuronal Migration Dynamics in the Developing Ferret Cortex","volume":"35","author":"Gertz","year":"2015","journal-title":"The Journal of Neuroscience"},{"key":"bib43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3109\/02713683.2014.914543","article-title":"Translating ocular biomechanics into clinical practice: current state and future prospects","volume":"40","author":"Girard","year":"2015","journal-title":"Current Eye Research"},{"key":"bib44","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1016\/j.neuron.2007.09.036","article-title":"Nonapical symmetric divisions underlie horizontal cell layer formation in the developing retina in vivo","volume":"56","author":"Godinho","year":"2007","journal-title":"Neuron"},{"key":"bib45","doi-asserted-by":"publisher","DOI":"10.1242\/dev.160739","article-title":"Nppa and Nppb act redundantly during zebrafish cardiac development to confine AVC marker expression and reduce cardiac jelly volume","volume":"145","author":"Grassini","year":"2018","journal-title":"Development (Cambridge, England)"},{"key":"bib46","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1203\/00006450-200012000-00004","article-title":"Mechanisms and disturbances of neuronal migration","volume":"48","author":"Gressens","year":"2000","journal-title":"Pediatric Research"},{"key":"bib47","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1038\/nrm1550","article-title":"The nuclear lamina comes of age","volume":"6","author":"Gruenbaum","year":"2005","journal-title":"Nature Reviews. Molecular Cell Biology"},{"key":"bib48","article-title":"BrillouinAcquisition","volume-title":"GitHub","author":"GuckLab \u2013 BrillouinMicroscopy","year":"2022","unstructured":"GuckLab \u2013 BrillouinMicroscopy. 2022. BrillouinAcquisition. GitHub. 4321f1e. https:\/\/github.com\/BrillouinMicroscopy\/BrillouinAcquisition."},{"key":"bib49","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1083\/jcb.200406063","article-title":"Cell migration without a lamellipodium: translation of actin dynamics into cell movement mediated by tropomyosin","volume":"168","author":"Gupton","year":"2005","journal-title":"The Journal of Cell Biology"},{"key":"bib50","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1083\/jcb.201308029","article-title":"Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival","volume":"204","author":"Harada","year":"2014","journal-title":"The Journal of Cell Biology"},{"key":"bib51","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/0166-2236(90)90044-b","article-title":"Riding the glial monorail: a common mechanism for glial-guided neuronal migration in different regions of the developing mammalian brain","volume":"13","author":"Hatten","year":"1990","journal-title":"Trends in Neurosciences"},{"key":"bib52","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.devcel.2016.06.031","article-title":"Leading from the Back: The Role of the Uropod in Neutrophil Polarization and Migration","volume":"38","author":"Hind","year":"2016","journal-title":"Developmental Cell"},{"key":"bib53","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1002\/cne.901870303","article-title":"Differentiation of photoreceptors and horizontal cells in the embryonic mouse retina: an electron microscopic, serial section analysis","volume":"187","author":"Hinds","year":"1979","journal-title":"The Journal of Comparative Neurology"},{"key":"bib54","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/S1084-9521(03)00008-9","article-title":"Cellular and molecular mechanisms of neuronal migration in neocortical development","volume":"14","author":"Honda","year":"2003","journal-title":"Seminars in Cell & Developmental Biology"},{"key":"bib55","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1006\/dbio.1998.9031","article-title":"Retinal Neurogenesis: The Formation of the Initial Central Patch of Postmitotic Cells","volume":"207","author":"Hu","year":"1999","journal-title":"Developmental Biology"},{"key":"bib56","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1109\/MCSE.2007.55","article-title":"Matplotlib: A 2D Graphics Environment","volume":"9","author":"Hunter","year":"2007","journal-title":"Computing in Science & Engineering"},{"key":"bib57","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1083\/jcb.201604095","article-title":"Independent modes of ganglion cell translocation ensure correct lamination of the zebrafish retina","volume":"215","author":"Icha","year":"2016","journal-title":"The Journal of Cell Biology"},{"key":"bib58","doi-asserted-by":"publisher","DOI":"10.3791\/53966","article-title":"Using Light Sheet Fluorescence Microscopy to Image Zebrafish Eye Development","volume":"e53966","author":"Icha","year":"2016","journal-title":"Journal of Visualized Experiments"},{"key":"bib59","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1016\/j.devcel.2009.08.012","article-title":"Actin dynamics at the leading edge: from simple machinery to complex networks","volume":"17","author":"Insall","year":"2009","journal-title":"Developmental Cell"},{"key":"bib60","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1016\/j.bpj.2009.06.021","article-title":"Vascular smooth muscle cell durotaxis depends on substrate stiffness gradient strength","volume":"97","author":"Isenberg","year":"2009","journal-title":"Biophysical Journal"},{"key":"bib61","doi-asserted-by":"publisher","first-page":"818","DOI":"10.1016\/j.tcb.2020.06.007","article-title":"Principles of Leukocyte Migration Strategies","volume":"30","author":"Kameritsch","year":"2020","journal-title":"Trends in Cell Biology"},{"key":"bib62","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.mcn.2003.10.006","article-title":"Dual phases of migration of cerebellar granule cells guided by axonal and dendritic leading processes","volume":"25","author":"Kawaji","year":"2004","journal-title":"Molecular and Cellular Neurosciences"},{"key":"bib63","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1016\/s0896-6273(01)00312-9","article-title":"Retinal ganglion cell genesis requires lakritz, a Zebrafish atonal Homolog","volume":"30","author":"Kay","year":"2001","journal-title":"Neuron"},{"key":"bib64","doi-asserted-by":"publisher","first-page":"1331","DOI":"10.1242\/dev.01040","article-title":"Transient requirement for ganglion cells during assembly of retinal synaptic layers","volume":"131","author":"Kay","year":"2004","journal-title":"Development (Cambridge, England)"},{"key":"bib65","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1002\/aja.1002030302","article-title":"Stages of embryonic development of the zebrafish","volume":"203","author":"Kimmel","year":"1995","journal-title":"Developmental Dynamics"},{"key":"bib66","doi-asserted-by":"publisher","first-page":"1115","DOI":"10.1523\/JNEUROSCI.2254-13.2014","article-title":"Hippocampal pyramidal neurons switch from a multipolar migration mode to a novel \u201cclimbing\u201d migration mode during development","volume":"34","author":"Kitazawa","year":"2014","journal-title":"The Journal of Neuroscience"},{"key":"bib67","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1080\/19336918.2015.1061173","article-title":"Cancer cell migration in 3D tissue: negotiating space by proteolysis and nuclear deformability","volume":"9","author":"Krause","year":"2015","journal-title":"Cell Adhesion & Migration"},{"key":"bib68","doi-asserted-by":"publisher","first-page":"2603","DOI":"10.1073\/pnas.79.8.2603","article-title":"Polarization of the Golgi apparatus and the microtubule-organizing center in cultured fibroblasts at the edge of an experimental wound","volume":"79","author":"Kupfer","year":"1982","journal-title":"PNAS"},{"key":"bib69","doi-asserted-by":"publisher","first-page":"25768","DOI":"10.1074\/jbc.M513511200","article-title":"Lamins A and C but not lamin B1 regulate nuclear mechanics","volume":"281","author":"Lammerding","year":"2006","journal-title":"The Journal of Biological Chemistry"},{"key":"bib70","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1002\/cphy.c100038","article-title":"Mechanics of the nucleus","volume":"1","author":"Lammerding","year":"2011","journal-title":"Comprehensive Physiology"},{"key":"bib71","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1038\/nature06887","article-title":"Rapid leukocyte migration by integrin-independent flowing and squeezing","volume":"453","author":"Lammermann","year":"2008","journal-title":"Nature"},{"key":"bib72","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1016\/j.ceb.2009.05.003","article-title":"Mechanical modes of \u201camoeboid\u201d cell migration","volume":"21","author":"Lammermann","year":"2009","journal-title":"Current Opinion in Cell Biology"},{"key":"bib73","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1038\/ncb3426","article-title":"Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes","volume":"18","author":"Leithner","year":"2016","journal-title":"Nature Cell Biology"},{"key":"bib74","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/S0006-3495(00)76279-5","article-title":"Cell movement is guided by the rigidity of the substrate","volume":"79","author":"Lo","year":"2000","journal-title":"Biophysical Journal"},{"key":"bib75","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1016\/j.ceb.2011.08.001","article-title":"Orientation and function of the nuclear-centrosomal axis during cell migration","volume":"23","author":"Luxton","year":"2011","journal-title":"Current Opinion in Cell Biology"},{"key":"bib76","doi-asserted-by":"publisher","first-page":"1075","DOI":"10.1083\/jcb.201503115","article-title":"M\u00fcller glia provide essential tensile strength to the developing retina","volume":"210","author":"MacDonald","year":"2015","journal-title":"The Journal of Cell Biology"},{"key":"bib77","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1007\/978-3-030-44826-4_25","volume-title":"Eukaryome Impact on Human Intestine Homeostasis and Mucosal Immunology","author":"Manich","year":"2020"},{"key":"bib78","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1002\/JLB.3HI0120-589R","article-title":"Frontline Science: Dynamic cellular and subcellular features of migrating leukocytes revealed by in vivo lattice lightsheet microscopy","volume":"108","author":"Manley","year":"2020","journal-title":"Journal of Leukocyte Biology"},{"key":"bib79","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1038\/35097509","article-title":"A long, remarkable journey: tangential migration in the telencephalon","volume":"2","author":"Marin","year":"2001","journal-title":"Nature Reviews. Neuroscience"},{"key":"bib80","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1146\/annurev.neuro.26.041002.131058","article-title":"Cell migration in the forebrain","volume":"26","author":"Marin","year":"2003","journal-title":"Annual Review of Neuroscience"},{"key":"bib81","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1146\/annurev-bioeng-071910-124638","article-title":"Mechanical regulation of nuclear structure and function","volume":"14","author":"Martins","year":"2012","journal-title":"Annual Review of Biomedical Engineering"},{"key":"bib82","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.2006018","article-title":"A non-cell-autonomous actin redistribution enables isotropic retinal growth","volume":"16","author":"Matej\u010di\u0107","year":"2018","journal-title":"PLOS Biology"},{"key":"bib83","doi-asserted-by":"publisher","DOI":"10.1142\/S1793545817420019","article-title":"Viscoelasticity of amyloid plaques in transgenic mouse brain studied by Brillouin microspectroscopy and correlative Raman analysis","volume":"10","author":"Mattana","year":"2017","journal-title":"Journal of Innovative Optical Health Sciences"},{"key":"bib84","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.ceb.2016.01.011","article-title":"Squish and squeeze-the nucleus as a physical barrier during migration in confined environments","volume":"40","author":"McGregor","year":"2016","journal-title":"Current Opinion in Cell Biology"},{"key":"bib85","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/B978-0-12-391857-4.00009-4","article-title":"Methods for cell and particle tracking","volume":"504","author":"Meijering","year":"2012","journal-title":"Methods in Enzymology"},{"key":"bib86","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1007\/BF00520999","article-title":"A study of neurogenesis in the forebrain of opossum pouch young","volume":"130","author":"Morest","year":"1970","journal-title":"Zeitschrift For Anatomie Und Entwicklungsgeschichte"},{"key":"bib87","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1007\/BF00518815","article-title":"The pattern of neurogenesis in the retina of the rat","volume":"131","author":"Morest","year":"1970","journal-title":"Zeitschrift For Anatomie Und Entwicklungsgeschichte"},{"key":"bib88","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1038\/83967","article-title":"Two modes of radial migration in early development of the cerebral cortex","volume":"4","author":"Nadarajah","year":"2001","journal-title":"Nature Neuroscience"},{"key":"bib89","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1038\/nrn845","article-title":"Modes of neuronal migration in the developing cerebral cortex","volume":"3","author":"Nadarajah","year":"2002","journal-title":"Nature Reviews. Neuroscience"},{"key":"bib90","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1093\/cercor\/13.6.607","article-title":"Neuronal migration in the developing cerebral cortex: observations based on real-time imaging","volume":"13","author":"Nadarajah","year":"2003","journal-title":"Cerebral Cortex (New York, N.Y"},{"key":"bib91","doi-asserted-by":"publisher","first-page":"3247","DOI":"10.1007\/s00429-019-01971-0","article-title":"Non-radial tortuous migration with cell polarity alterations of newly generated granule neurons in the neonatal rat dentate gyrus","volume":"224","author":"Namba","year":"2019","journal-title":"Brain Structure & Function"},{"key":"bib92","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1038\/nn1172","article-title":"Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases","volume":"7","author":"Noctor","year":"2004","journal-title":"Nature Neuroscience"},{"key":"bib93","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1007\/BF01206671","article-title":"The mode of migration of neurons to the hippocampus: a Golgi and electron microscopic analysis in foetal rhesus monkey","volume":"8","author":"Nowakowski","year":"1979","journal-title":"Journal of Neurocytology"},{"key":"bib94","doi-asserted-by":"publisher","first-page":"2865","DOI":"10.1242\/dev.025049","article-title":"Pathfinding in a large vertebrate axon tract: isotypic interactions guide retinotectal axons at multiple choice points","volume":"135","author":"Pittman","year":"2008","journal-title":"Development (Cambridge, England)"},{"key":"bib95","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1038\/s41592-019-0543-3","article-title":"Brillouin microscopy: an emerging tool for mechanobiology","volume":"16","author":"Prevedel","year":"2019","journal-title":"Nature Methods"},{"key":"bib96","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2018.00484","article-title":"Neuronal Migration During Development of the Cerebellum","volume":"12","author":"Rahimi-Balaei","year":"2018","journal-title":"Frontiers in Cellular Neuroscience"},{"key":"bib97","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1002\/cne.901410303","article-title":"Neuron-glia relationship during granule cell migration in developing cerebellar cortex. A Golgi and electronmicroscopic study in Macacus Rhesus","volume":"141","author":"Rakic","year":"1971","journal-title":"The Journal of Comparative Neurology"},{"key":"bib98","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1002\/cne.901450105","article-title":"Mode of cell migration to the superficial layers of fetal monkey neocortex","volume":"145","author":"Rakic","year":"1972","journal-title":"The Journal of Comparative Neurology"},{"key":"bib99","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1002\/cne.20134","article-title":"Timing and topography of cell genesis in the rat retina","volume":"474","author":"Rapaport","year":"2004","journal-title":"The Journal of Comparative Neurology"},{"key":"bib100","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1038\/s41586-019-1087-5","article-title":"Nuclear positioning facilitates amoeboid migration along the path of least resistance","volume":"568","author":"Renkawitz","year":"2019","journal-title":"Nature"},{"key":"bib101","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1038\/nmeth.1220","article-title":"Lifeact: a versatile marker to visualize F-actin","volume":"5","author":"Riedl","year":"2008","journal-title":"Nature Methods"},{"key":"bib102","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1016\/j.ceb.2013.04.010","article-title":"Mechanical guidance of cell migration: lessons from chemotaxis","volume":"25","author":"Roca-Cusachs","year":"2013","journal-title":"Current Opinion in Cell Biology"},{"key":"bib103","doi-asserted-by":"publisher","DOI":"10.1101\/2021.02.08.430189","article-title":"Bidirectional Neuronal Migration Coordinates Retinal Morphogenesis by Preventing Spatial Competition","volume-title":"bioRxiv","author":"Rocha-Martins","year":"2021"},{"key":"bib104","doi-asserted-by":"publisher","first-page":"8610","DOI":"10.1074\/jbc.M112.441535","article-title":"Nuclear envelope composition determines the ability of neutrophil-type cells to passage through micron-scale constrictions","volume":"288","author":"Rowat","year":"2013","journal-title":"The Journal of Biological Chemistry"},{"key":"bib105","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02680","article-title":"Nuclear Deformation During Neutrophil Migration at Sites of Inflammation","volume":"9","author":"Salvermoser","year":"2018","journal-title":"Frontiers in Immunology"},{"key":"bib106","doi-asserted-by":"publisher","DOI":"10.1016\/j.dib.2020.105427","article-title":"A 3D Brillouin microscopy dataset of the in-vivo zebrafish eye","volume":"30","author":"S\u00e1nchez-Iranzo","year":"2020","journal-title":"Data in Brief"},{"key":"bib107","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2020.107907","article-title":"Axon Growth of CNS Neurons in Three Dimensions Is Amoeboid and Independent of Adhesions","volume":"32","author":"Santos","year":"2020","journal-title":"Cell Reports"},{"key":"bib108","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1016\/j.bpj.2011.08.008","article-title":"In vivo measurement of age-related stiffening in the crystalline lens by Brillouin optical microscopy","volume":"101","author":"Scarcelli","year":"2011","journal-title":"Biophysical Journal"},{"key":"bib109","doi-asserted-by":"publisher","first-page":"9197","DOI":"10.1364\/OE.20.009197","article-title":"In vivo Brillouin optical microscopy of the human eye","volume":"20","author":"Scarcelli","year":"2012","journal-title":"Optics Express"},{"key":"bib110","doi-asserted-by":"publisher","first-page":"911","DOI":"10.1016\/j.bpj.2018.07.027","article-title":"Mechanical Mapping of Spinal Cord Growth and Repair in Living Zebrafish Larvae by Brillouin Imaging","volume":"115","author":"Schl\u00fc\u00dfler","year":"2018","journal-title":"Biophysical Journal"},{"key":"bib111","article-title":"BrillouinMicroscopy\/BrillouinEvaluation","volume-title":"GitHub","author":"Schl\u00fc\u00dfler","year":"2022","unstructured":"Schl\u00fc\u00dfler R. 2022. BrillouinMicroscopy\/BrillouinEvaluation. GitHub. swh:1:rev:3070654dc2b03fcacef8bd236935105cab128964. https:\/\/github.com\/BrillouinMicroscopy\/BrillouinEvaluation."},{"key":"bib112","doi-asserted-by":"publisher","first-page":"9426","DOI":"10.1523\/JNEUROSCI.0650-11.2011","article-title":"The outermost region of the developing cortical plate is crucial for both the switch of the radial migration mode and the Dab1-dependent \u201cinside-out\u201d lamination in the neocortex","volume":"31","author":"Sekine","year":"2011","journal-title":"The Journal of Neuroscience"},{"key":"bib113","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1002\/cne.901790407","article-title":"The development of the cerebral cortex in the embryonic mouse: an electron microscopic serial section analysis","volume":"179","author":"Shoukimas","year":"1978","journal-title":"The Journal of Comparative Neurology"},{"key":"bib114","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1002\/cne.901300204","article-title":"The development of hippocampal and dorsolateral pallial regions of the cerebral hemisphere in fetal rabbits. 3. Twenty-nine millimeter stage, marginal lamina","volume":"130","author":"Stensaas","year":"1967","journal-title":"The Journal of Comparative Neurology"},{"key":"bib115","doi-asserted-by":"publisher","DOI":"10.1126\/science.1240104","article-title":"Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation","volume":"341","author":"Swift","year":"2013","journal-title":"Science (New York, N.Y.)"},{"key":"bib116","doi-asserted-by":"crossref","first-page":"9996","DOI":"10.1523\/JNEUROSCI.23-31-09996.2003","article-title":"Multipolar migration: the third mode of radial neuronal migration in the developing cerebral cortex","volume":"23","author":"Tabata","year":"2003","journal-title":"The Journal of Neuroscience"},{"key":"bib117","doi-asserted-by":"publisher","first-page":"2167","DOI":"10.1242\/dev.02382","article-title":"Multidirectional and multizonal tangential migration of GABAergic interneurons in the developing cerebral cortex","volume":"133","author":"Tanaka","year":"2006","journal-title":"Development (Cambridge, England)"},{"key":"bib118","doi-asserted-by":"publisher","first-page":"1300","DOI":"10.1523\/JNEUROSCI.5446-08.2009","article-title":"Random walk behavior of migrating cortical interneurons in the marginal zone: time-lapse analysis in flat-mount cortex","volume":"29","author":"Tanaka","year":"2009","journal-title":"The Journal of Neuroscience"},{"key":"bib119","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2020.00687","article-title":"The Mechanics of Mitotic Cell Rounding","volume":"8","author":"Taubenberger","year":"2020","journal-title":"Frontiers in Cell and Developmental Biology"},{"key":"bib120","doi-asserted-by":"crossref","first-page":"9933","DOI":"10.1016\/S0021-9258(19)83607-4","article-title":"Laminin--a glycoprotein from basement membranes","volume":"254","author":"Timpl","year":"1979","journal-title":"The Journal of Biological Chemistry"},{"key":"bib121","doi-asserted-by":"publisher","first-page":"2369","DOI":"10.1002\/cphy.c110012","article-title":"Cell migration","volume":"2","author":"Trepat","year":"2012","journal-title":"Comprehensive Physiology"},{"key":"bib122","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1038\/ncb3284","article-title":"Innate control of actin nucleation determines two distinct migration behaviours in dendritic cells","volume":"18","author":"Vargas","year":"2016","journal-title":"Nature Cell Biology"},{"key":"bib123","doi-asserted-by":"publisher","first-page":"1342","DOI":"10.1126\/science.3137660","article-title":"Clonally related cortical cells show several migration patterns","volume":"241","author":"Walsh","year":"1988","journal-title":"Science (New York, N.Y.)"},{"key":"bib124","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1126\/science.1228456","article-title":"Interstitial dendritic cell guidance by haptotactic chemokine gradients","volume":"339","author":"Weber","year":"2013","journal-title":"Science (New York, N.Y.)"},{"key":"bib125","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1016\/j.celrep.2014.03.014","article-title":"Mitotic position and morphology of committed precursor cells in the zebrafish retina adapt to architectural changes upon tissue maturation","volume":"7","author":"Weber","year":"2014","journal-title":"Cell Reports"},{"key":"bib126","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1083\/jcb.200209006","article-title":"Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis","volume":"160","author":"Wolf","year":"2003","journal-title":"The Journal of Cell Biology"},{"key":"bib127","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1038\/ncb1616","article-title":"Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion","volume":"9","author":"Wolf","year":"2007","journal-title":"Nature Cell Biology"},{"key":"bib128","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1016\/j.tcb.2011.09.006","article-title":"Extracellular matrix determinants of proteolytic and non-proteolytic cell migration","volume":"21","author":"Wolf","year":"2011","journal-title":"Trends in Cell Biology"},{"key":"bib129","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1016\/j.cell.2011.12.034","article-title":"Arp2\/3 is critical for lamellipodia and response to extracellular matrix cues but is dispensable for chemotaxis","volume":"148","author":"Wu","year":"2012","journal-title":"Cell"},{"key":"bib130","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1038\/s41580-019-0172-9","article-title":"Mechanisms of 3D cell migration","volume":"20","author":"Yamada","year":"2019","journal-title":"Nature Reviews. Molecular Cell Biology"},{"key":"bib131","doi-asserted-by":"publisher","first-page":"3272","DOI":"10.1083\/jcb.201901077","article-title":"Cell and tissue morphology determine actin-dependent nuclear migration mechanisms in neuroepithelia","volume":"218","author":"Yanakieva","year":"2019","journal-title":"The Journal of Cell Biology"},{"key":"bib132","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1016\/j.devcel.2009.11.015","article-title":"Differential regulation of protrusion and polarity by PI3K during neutrophil motility in live zebrafish","volume":"18","author":"Yoo","year":"2010","journal-title":"Developmental Cell"},{"key":"bib133","doi-asserted-by":"publisher","first-page":"3833","DOI":"10.1242\/jcs.03152","article-title":"Dissection of amoeboid movement into two mechanically distinct modes","volume":"119","author":"Yoshida","year":"2006","journal-title":"Journal of Cell Science"},{"key":"bib134","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1039\/c6lc01443g","article-title":"Brillouin flow cytometry for label-free mechanical phenotyping of the nucleus","volume":"17","author":"Zhang","year":"2017","journal-title":"Lab on a Chip"}],"container-title":["eLife"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/cdn.elifesciences.org\/articles\/76408\/elife-76408-v2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/cdn.elifesciences.org\/articles\/76408\/elife-76408-v2.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/elifesciences.org\/articles\/76408","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T21:15:04Z","timestamp":1697058904000},"score":1,"resource":{"primary":{"URL":"https:\/\/elifesciences.org\/articles\/76408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,31]]},"references-count":134,"alternative-id":["10.7554\/eLife.76408"],"URL":"https:\/\/doi.org\/10.7554\/elife.76408","archive":["CLOCKSS"],"relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2021.10.15.464510","asserted-by":"subject"},{"id-type":"doi","id":"10.1101\/2021.10.15.464510","asserted-by":"object"}],"has-review":[{"id-type":"doi","id":"10.7554\/eLife.76408.sa1","asserted-by":"object"},{"id-type":"doi","id":"10.7554\/eLife.76408.sa0","asserted-by":"object"},{"id-type":"doi","id":"10.7554\/eLife.76408.sa2","asserted-by":"object"}]},"ISSN":["2050-084X"],"issn-type":[{"value":"2050-084X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,31]]},"assertion":[{"value":"single anonymised","name":"peer_review_transparency","label":"Peer review transparency","group":{"name":"peer_review_taxonomy"}},{"value":"other reviewer(s), editor","name":"peer_review_interaction","label":"Peer review interaction","group":{"name":"peer_review_taxonomy"}},{"value":"review summaries, review reports, author\/editor communication, reviewer identities reviewer opt in, editor identities","name":"peer_review_published","label":"Peer review published","group":{"name":"peer_review_taxonomy"}},{"value":"open (sign in with ORCID iD required)","name":"post_publication_commenting","label":"Post publication commenting","group":{"name":"post_publication_commenting"}}],"article-number":"e76408"}}