{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T21:17:14Z","timestamp":1789161434970,"version":"build-2803163510"},"reference-count":67,"publisher":"eLife Sciences Publications, Ltd","license":[{"start":{"date-parts":[[2023,12,20]],"date-time":"2023-12-20T00:00:00Z","timestamp":1703030400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,12,20]],"date-time":"2023-12-20T00:00:00Z","timestamp":1703030400000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,12,20]],"date-time":"2023-12-20T00:00:00Z","timestamp":1703030400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elifesciences.org"],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2023,12,19]]},"abstract":"<jats:p>Response inhibition in humans is important to avoid undesirable behavioral action consequences. Neuroimaging and lesion studies point to a locus of inhibitory control in the right inferior frontal gyrus (rIFG). Electrophysiology studies have implicated a downstream event-related potential from rIFG, the fronto-central P300, as a putative neural marker of the success and timing of inhibition over behavioral responses. However, it remains to be established whether rIFG effectively drives inhibition and which aspect of P300 activity uniquely indexes inhibitory control\u2014ERP timing or amplitude. Here, we dissect the connection between rIFG and P300 for inhibition by using transcranial-focused ultrasound (tFUS) to target rIFG of human subjects while they performed a Stop-Signal task. By applying tFUS simultaneously with different task events, we found behavioral inhibition was improved, but only when applied to rIFG simultaneously with a \u2018stop\u2019 signal. Improved inhibition through tFUS to rIFG was indexed by faster stopping times that aligned with significantly shorter N200\/P300 onset latencies. In contrast, P300 amplitude was modulated during tFUS across all groups without a paired change in behavior. Using tFUS, we provide evidence for a causal connection between anatomy, behavior, and electrophysiology underlying response inhibition.<\/jats:p>","DOI":"10.7554\/elife.86190","type":"journal-article","created":{"date-parts":[[2023,12,20]],"date-time":"2023-12-20T08:00:33Z","timestamp":1703059233000},"update-policy":"https:\/\/doi.org\/10.7554\/elife.86190","source":"Crossref","is-referenced-by-count":25,"title":["Transcranial focused ultrasound to human rIFG improves response inhibition through modulation of the P300 onset latency"],"prefix":"10.7554","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2378-6854","authenticated-orcid":true,"given":"Justin M","family":"Fine","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03efmqc40","id-type":"ROR","asserted-by":"publisher"}],"name":"School of Biological and Health Systems Engineering, Arizona State University","place":["Tempe, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Archana S","family":"Mysore","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03efmqc40","id-type":"ROR","asserted-by":"publisher"}],"name":"School of Biological and Health Systems Engineering, Arizona State University","place":["Tempe, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria E","family":"Fini","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03efmqc40","id-type":"ROR","asserted-by":"publisher"}],"name":"School of Biological and Health Systems Engineering, Arizona State University","place":["Tempe, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William J","family":"Tyler","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03efmqc40","id-type":"ROR","asserted-by":"publisher"}],"name":"School of Biological and Health Systems Engineering, Arizona State University","place":["Tempe, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Santello","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03efmqc40","id-type":"ROR","asserted-by":"publisher"}],"name":"School of Biological and Health Systems Engineering, Arizona State University","place":["Tempe, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4374","published-online":{"date-parts":[[2023,12,20]]},"reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"e55","DOI":"10.1016\/j.biopsych.2010.07.024","article-title":"From reactive to proactive and selective control: developing a richer model for stopping inappropriate responses","volume":"69","author":"Aron","year":"2011","journal-title":"Biological Psychiatry"},{"key":"bib2","doi-asserted-by":"publisher","first-page":"11489","DOI":"10.1523\/JNEUROSCI.2348-16.2016","article-title":"Frontosubthalamic circuits for control of action and cognition","volume":"36","author":"Aron","year":"2016","journal-title":"The Journal of Neuroscience"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1121\/1.1529663","article-title":"Experimental demonstration of noninvasive transskull adaptive focusing based on prior computed tomography scans","volume":"113","author":"Aubry","year":"2003","journal-title":"The Journal of the Acoustical Society of America"},{"key":"bib4","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/j.pneurobio.2013.06.005","article-title":"Inhibition and impulsivity: behavioral and neural basis of response control","volume":"108","author":"Bari","year":"2013","journal-title":"Progress in Neurobiology"},{"key":"bib5","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/j.ijpsycho.2004.07.005","article-title":"The pure electrophysiology of stopping","volume":"55","author":"Bekker","year":"2005","journal-title":"International Journal of Psychophysiology"},{"key":"bib6","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abf4355","article-title":"Severe violations of independence in response inhibition tasks","volume":"7","author":"Bissett","year":"2021","journal-title":"Science Advances"},{"key":"bib7","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1037\/0033-295X.114.2.376","article-title":"Inhibitory control in mind and brain: an interactive race model of countermanding saccades","volume":"114","author":"Boucher","year":"2007","journal-title":"Psychological Review"},{"key":"bib8","doi-asserted-by":"publisher","first-page":"1527","DOI":"10.1016\/j.brs.2020.08.014","article-title":"Transcranial ultrasound stimulation in humans is associated with an auditory confound that can be effectively masked","volume":"13","author":"Braun","year":"2020","journal-title":"Brain Stimulation"},{"key":"bib9","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1162\/089892906775990606","article-title":"Executive \u201cbrake failure\u201d following deactivation of human frontal lobe","volume":"18","author":"Chambers","year":"2006","journal-title":"Journal of Cognitive Neuroscience"},{"key":"bib10","doi-asserted-by":"publisher","first-page":"3638","DOI":"10.1152\/jn.00685.2007","article-title":"Dissociable Mechanisms of Cognitive Control in Prefrontal and Premotor Cortex","volume":"98","author":"Chambers","year":"2007","journal-title":"Journal of Neurophysiology"},{"key":"bib11","doi-asserted-by":"publisher","first-page":"1114","DOI":"10.1109\/TBME.2019.2930186","article-title":"Evaluation of Artifact Subspace Reconstruction for Automatic Artifact Components Removal in Multi-Channel EEG Recordings","volume":"67","author":"Chang","year":"2018","journal-title":"IEEE Transactions on Bio-Medical Engineering"},{"key":"bib12","doi-asserted-by":"publisher","first-page":"15870","DOI":"10.1523\/JNEUROSCI.3645-09.2009","article-title":"Preparation to inhibit a response complements response inhibition during performance of a stop-signal task","volume":"29","author":"Chikazoe","year":"2009","journal-title":"The Journal of Neuroscience"},{"key":"bib13","doi-asserted-by":"crossref","DOI":"10.1002\/9781118920497.ch1","volume-title":"Cognitive Control: Core Constructs and Current Considerations","author":"Cohen","year":"2017"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"1951","DOI":"10.1016\/s0042-6989(01)00084-0","article-title":"Countermanding saccades with auditory stop signals: testing the race model","volume":"41","author":"Colonius","year":"2001","journal-title":"Vision Research"},{"key":"bib15","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1016\/j.neuron.2008.04.017","article-title":"The reorienting system of the human brain: from environment to theory of mind","volume":"58","author":"Corbetta","year":"2008","journal-title":"Neuron"},{"key":"bib16","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.neuroimage.2015.11.044","article-title":"The right inferior frontal cortex in response inhibition: A tDCS-ERP co-registration study","volume":"140","author":"Cunillera","year":"2016","journal-title":"NeuroImage"},{"key":"bib17","doi-asserted-by":"publisher","DOI":"10.12987\/9780300255881","volume-title":"Causal Inference: The Mixtape","author":"Cunningham","year":"2021"},{"key":"bib18","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.jneumeth.2003.10.009","article-title":"EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis","volume":"134","author":"Delorme","year":"2004","journal-title":"Journal of Neuroscience Methods"},{"key":"bib19","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0030135","article-title":"Independent EEG sources are dipolar","volume":"7","author":"Delorme","year":"2012","journal-title":"PLOS ONE"},{"key":"bib20","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.7838","article-title":"Unfold: an integrated toolbox for overlap correction, non-linear modeling, and regression-based EEG analysis","volume":"7","author":"Ehinger","year":"2019","journal-title":"PeerJ"},{"key":"bib21","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1016\/j.neuroimage.2010.02.043","article-title":"Conflict and inhibition differentially affect the N200\/P300 complex in a combined go\/nogo and stop-signal task","volume":"51","author":"Enriquez-Geppert","year":"2010","journal-title":"NeuroImage"},{"key":"bib22","article-title":"Tfus_Inhibition_Elife","volume-title":"Software Heritage","author":"Fine","year":"2024","unstructured":"Fine JM. 2024. Tfus_Inhibition_Elife. Software Heritage. swh:1:rev:8d0c07a0fc680863c2b4ad1b9fc8a4295d7a082a. https:\/\/archive.softwareheritage.org\/swh:1:dir:e9d48536fed7de263da2e673007bff7634cfff8e;origin=https:\/\/github.com\/JustFineNeuro\/tFUS_Inhibition_Elife;visit=swh:1:snp:45e89efe3d690fdbc688f6f8e9b09c8ab1c8564b;anchor=swh:1:rev:8d0c07a0fc680863c2b4ad1b9fc8a4295d7a082a."},{"key":"bib23","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1080\/09540261.2017.1302924","article-title":"Transcranial focused ultrasound: a new tool for non-invasive neuromodulation","volume":"29","author":"Fini","year":"2017","journal-title":"International Review of Psychiatry"},{"key":"bib24","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1016\/j.neuron.2019.01.019","article-title":"Manipulation of subcortical and deep cortical activity in the primate brain using transcranial focused ultrasound stimulation","volume":"101","author":"Folloni","year":"2019","journal-title":"Neuron"},{"key":"bib25","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1080\/00031305.2012.676329","article-title":"Estimating the correlation in bivariate normal data with known variances and small sample sizes","volume":"66","author":"Fosdick","year":"2012","journal-title":"The American Statistician"},{"key":"bib26","doi-asserted-by":"publisher","first-page":"900","DOI":"10.1111\/psyp.12070","article-title":"EEG signatures associated with stopping are sensitive to preparation","volume":"50","author":"Greenhouse","year":"2013","journal-title":"Psychophysiology"},{"key":"bib27","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1111\/j.1469-8986.2005.00278.x","article-title":"Brain potentials associated with expected and unexpected good and bad outcomes","volume":"42","author":"Hajcak","year":"2005","journal-title":"Psychophysiology"},{"key":"bib28","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1152\/jn.1998.79.2.817","article-title":"Role of frontal eye fields in countermanding saccades: visual, movement, and fixation activity","volume":"79","author":"Hanes","year":"1998","journal-title":"Journal of Neurophysiology"},{"key":"bib29","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1016\/j.ijpsycho.2012.08.001","article-title":"Electroencephalography of response inhibition tasks: functional networks and cognitive contributions","volume":"87","author":"Huster","year":"2013","journal-title":"International Journal of Psychophysiology"},{"key":"bib30","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1016\/j.cortex.2020.05.021","article-title":"The P300 as marker of inhibitory control - Fact or fiction?","volume":"132","author":"Huster","year":"2020","journal-title":"Cortex; a Journal Devoted to the Study of the Nervous System and Behavior"},{"key":"bib31","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1046\/j.1469-8986.2003.00127.x","article-title":"ERP components associated with successful and unsuccessful stopping in a stop-signal task","volume":"41","author":"Kok","year":"2004","journal-title":"Psychophysiology"},{"key":"bib32","doi-asserted-by":"publisher","first-page":"35","DOI":"10.20982\/tqmp.04.1.p035","article-title":"How to use MATLAB to fit the ex-Gaussian and other probability functions to a distribution of response times","volume":"4","author":"Lacouture","year":"2008","journal-title":"Tutorials in Quantitative Methods for Psychology"},{"key":"bib33","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1038\/nn.3620","article-title":"Transcranial focused ultrasound modulates the activity of primary somatosensory cortex in humans","volume":"17","author":"Legon","year":"2014","journal-title":"Nature Neuroscience"},{"key":"bib34","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-28320-1","article-title":"Transcranial focused ultrasound neuromodulation of the human primary motor cortex","volume":"8","author":"Legon","year":"2018","journal-title":"Scientific Reports"},{"key":"bib35","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1111\/j.1749-6632.2011.05958.x","article-title":"Cognitive control and right ventrolateral prefrontal cortex: reflexive reorienting, motor inhibition, and action updating","volume":"1224","author":"Levy","year":"2011","journal-title":"Annals of the New York Academy of Sciences"},{"key":"bib36","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1016\/j.neuroimage.2012.09.014","article-title":"Convolution models for induced electromagnetic responses","volume":"64","author":"Litvak","year":"2013","journal-title":"NeuroImage"},{"key":"bib37","doi-asserted-by":"publisher","first-page":"9059","DOI":"10.1523\/JNEUROSCI.6164-08.2009","article-title":"Proactive inhibitory control and attractor dynamics in countermanding action: a spiking neural circuit model","volume":"29","author":"Lo","year":"2009","journal-title":"The Journal of Neuroscience"},{"key":"bib38","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1037\/0033-295X.91.3.295","article-title":"On the ability to inhibit thought and action: A theory of an act of control","volume":"91","author":"Logan","year":"1984","journal-title":"Psychological Review"},{"key":"bib39","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1037\/a0038893","article-title":"Inhibitory control in mind and brain 2.0: blocked-input models of saccadic countermanding","volume":"122","author":"Logan","year":"2015","journal-title":"Psychological Review"},{"key":"bib40","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1111\/psyp.12639","article-title":"How to get statistically significant effects in any ERP experiment (and why you shouldn\u2019t)","volume":"54","author":"Luck","year":"2017","journal-title":"Psychophysiology"},{"key":"bib41","doi-asserted-by":"publisher","first-page":"314","DOI":"10.3758\/s13428-011-0168-7","article-title":"OpenSesame: an open-source, graphical experiment builder for the social sciences","volume":"44","author":"Math\u00f4t","year":"2012","journal-title":"Behavior Research Methods"},{"key":"bib42","doi-asserted-by":"publisher","DOI":"10.3389\/fneng.2012.00012","article-title":"Stop-event-related potentials from intracranial electrodes reveal a key role of premotor and motor cortices in stopping ongoing movements","volume":"5","author":"Mattia","year":"2012","journal-title":"Frontiers in Neuroengineering"},{"key":"bib43","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.1037\/a0030543","article-title":"Bayesian parametric estimation of stop-signal reaction time distributions","volume":"142","author":"Matzke","year":"2013","journal-title":"Journal of Experimental Psychology. General"},{"key":"bib44","doi-asserted-by":"publisher","first-page":"13240","DOI":"10.1073\/pnas.1000674107","article-title":"Cortical and subcortical interactions during action reprogramming and their related white matter pathways","volume":"107","author":"Neubert","year":"2010","journal-title":"PNAS"},{"key":"bib45","doi-asserted-by":"publisher","first-page":"1805","DOI":"10.1109\/ICASSP.2008.4517982","article-title":"Newton method for the ICA mixture model","author":"Palmer","year":"2008","unstructured":"Palmer JA, Makeig S, Kreutz-Delgado K, Rao BD. 2008. Newton method for the ICA mixture model. ICASSP 2008. IEEE International Conference on Acoustic, Speech and Signal Processes."},{"key":"bib46","doi-asserted-by":"publisher","first-page":"2128","DOI":"10.1016\/j.clinph.2007.04.019","article-title":"Updating P300: an integrative theory of P3a and P3b","volume":"118","author":"Polich","year":"2007","journal-title":"Clinical Neurophysiology"},{"key":"bib47","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1016\/j.bandc.2004.07.002","article-title":"Effects of stop-signal probability in the stop-signal paradigm: the N2\/P3 complex further validated","volume":"56","author":"Ramautar","year":"2004","journal-title":"Brain and Cognition"},{"key":"bib48","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.npbr.2020.06.004","article-title":"A double-blind pilot study of transcranial ultrasound (TUS) as A five-day intervention: TUS mitigates worry among depressed participants","volume":"37","author":"Reznik","year":"2020","journal-title":"Neurology, Psychiatry and Brain Research"},{"key":"bib49","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2020.00052","article-title":"Transcranial focused ultrasound to the right prefrontal cortex improves mood and alters functional connectivity in humans","volume":"14","author":"Sanguinetti","year":"2020","journal-title":"Frontiers in Human Neuroscience"},{"key":"bib50","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1152\/jn.00459.2020","article-title":"Double-blind disruption of right inferior frontal cortex with TMS reduces right frontal beta power for action stopping","volume":"125","author":"Sundby","year":"2021","journal-title":"Journal of Neurophysiology"},{"key":"bib51","doi-asserted-by":"publisher","DOI":"10.1117\/1.3360308","article-title":"k-Wave: MATLAB toolbox for the simulation and reconstruction of photoacoustic wave fields","volume":"15","author":"Treeby","year":"2010","journal-title":"Journal of Biomedical Optics"},{"key":"bib52","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1016\/j.neuron.2010.05.008","article-title":"Transcranial pulsed ultrasound stimulates intact brain circuits","volume":"66","author":"Tufail","year":"2010","journal-title":"Neuron"},{"key":"bib53","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/j.conb.2018.04.011","article-title":"Ultrasonic modulation of neural circuit activity","volume":"50","author":"Tyler","year":"2018","journal-title":"Current Opinion in Neurobiology"},{"key":"bib54","doi-asserted-by":"publisher","first-page":"363","DOI":"10.3844\/jcssp.2010.363.368","article-title":"Computational Complexity between K-Means and K-Medoids Clustering Algorithms for Normal and Uniform Distributions of Data Points","volume":"6","author":"Velmurugan","year":"2010","journal-title":"Journal of Computer Science"},{"key":"bib55","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1016\/j.tics.2008.07.005","article-title":"Response inhibition in the stop-signal paradigm","volume":"12","author":"Verbruggen","year":"2008","journal-title":"Trends in Cognitive Sciences"},{"key":"bib56","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.46323","article-title":"A consensus guide to capturing the ability to inhibit actions and impulsive behaviors in the stop-signal task","volume":"8","author":"Verbruggen","year":"2019","journal-title":"eLife"},{"key":"bib57","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.40541","article-title":"Offline impact of transcranial focused ultrasound on cortical activation in primates","volume":"8","author":"Verhagen","year":"2019","journal-title":"eLife"},{"key":"bib58","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1162\/jocn_a_01183","article-title":"Establishing a right frontal beta signature for stopping action in scalp EEG: Implications for testing inhibitory control in other task contexts","volume":"30","author":"Wagner","year":"2018","journal-title":"Journal of Cognitive Neuroscience"},{"key":"bib59","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.ijpsycho.2019.01.004","article-title":"Common neural processes during action-stopping and infrequent stimulus detection: The frontocentral P3 as an index of generic motor inhibition","volume":"163","author":"Waller","year":"2021","journal-title":"International Journal of Psychophysiology"},{"key":"bib60","doi-asserted-by":"publisher","first-page":"19611","DOI":"10.1523\/JNEUROSCI.3468-13.2013","article-title":"Chronometric electrical stimulation of right inferior frontal cortex increases motor braking","volume":"33","author":"Wessel","year":"2013","journal-title":"The Journal of Neuroscience"},{"key":"bib61","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1111\/psyp.12374","article-title":"It\u2019s not too late: the onset of the frontocentral P3 indexes successful response inhibition in the stop-signal paradigm","volume":"52","author":"Wessel","year":"2015","journal-title":"Psychophysiology"},{"key":"bib62","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms11195","article-title":"Surprise disrupts cognition via a fronto-basal ganglia suppressive mechanism","volume":"7","author":"Wessel","year":"2016","journal-title":"Nature Communications"},{"key":"bib63","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/j.neuron.2016.12.013","article-title":"On the globality of motor suppression: Unexpected events and their influence on behavior and cognition","volume":"93","author":"Wessel","year":"2017","journal-title":"Neuron"},{"key":"bib64","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.42959","article-title":"Non-selective inhibition of inappropriate motor-tendencies during response-conflict by a fronto-subthalamic mechanism","volume":"8","author":"Wessel","year":"2019","journal-title":"eLife"},{"key":"bib65","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-40998-0","article-title":"Transcranial focused ultrasound-mediated neurochemical and functional connectivity changes in deep cortical regions in humans","volume":"14","author":"Yaakub","year":"2023","journal-title":"Nature Communications"},{"key":"bib66","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-28040-1","article-title":"Focused ultrasound excites cortical neurons via mechanosensitive calcium accumulation and ion channel amplification","volume":"13","author":"Yoo","year":"2022","journal-title":"Nature Communications"},{"key":"bib67","doi-asserted-by":"publisher","first-page":"1559","DOI":"10.1111\/psyp.12521","article-title":"Latency as a region contrast: Measuring ERP latency differences with Dynamic Time Warping","volume":"52","author":"Zoumpoulaki","year":"2015","journal-title":"Psychophysiology"}],"container-title":["eLife"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/cdn.elifesciences.org\/articles\/86190\/elife-86190-v2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/cdn.elifesciences.org\/articles\/86190\/elife-86190-v2.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/elifesciences.org\/articles\/86190","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,19]],"date-time":"2024-01-19T04:30:55Z","timestamp":1705638655000},"score":1,"resource":{"primary":{"URL":"https:\/\/elifesciences.org\/articles\/86190"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,20]]},"references-count":67,"alternative-id":["10.7554\/eLife.86190"],"URL":"https:\/\/doi.org\/10.7554\/elife.86190","archive":["CLOCKSS"],"relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/649665","asserted-by":"subject"},{"id-type":"doi","id":"10.1101\/649665","asserted-by":"subject"},{"id-type":"doi","id":"10.1101\/649665","asserted-by":"object"}],"has-review":[{"id-type":"doi","id":"10.7554\/eLife.86190.sa2","asserted-by":"object"},{"id-type":"doi","id":"10.7554\/eLife.86190.sa0","asserted-by":"object"},{"id-type":"doi","id":"10.7554\/eLife.86190.sa1","asserted-by":"object"}]},"ISSN":["2050-084X"],"issn-type":[{"value":"2050-084X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,20]]},"assertion":[{"value":"single anonymised","name":"peer_review_transparency","label":"Peer review transparency","group":{"name":"peer_review_taxonomy"}},{"value":"other reviewer(s), editor","name":"peer_review_interaction","label":"Peer review interaction","group":{"name":"peer_review_taxonomy"}},{"value":"review summaries, review reports, author\/editor communication, reviewer identities reviewer opt in, editor identities","name":"peer_review_published","label":"Peer review published","group":{"name":"peer_review_taxonomy"}},{"value":"open (sign in with ORCID iD required)","name":"post_publication_commenting","label":"Post publication commenting","group":{"name":"post_publication_commenting"}}],"article-number":"e86190"}}