{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T10:37:04Z","timestamp":1787567824576,"version":"build-2736575974"},"reference-count":52,"publisher":"eLife Sciences Publications, Ltd","license":[{"start":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T00:00:00Z","timestamp":1742342400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T00:00:00Z","timestamp":1742342400000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T00:00:00Z","timestamp":1742342400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["#1R01HD090050-0"],"award-info":[{"award-number":["#1R01HD090050-0"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["#1R01DK132120"],"award-info":[{"award-number":["#1R01DK132120"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K99HD103778"],"award-info":[{"award-number":["K99HD103778"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["#R00HD103778"],"award-info":[{"award-number":["#R00HD103778"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["#5R01HD039963"],"award-info":[{"award-number":["#5R01HD039963"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006510","name":"Duke University","doi-asserted-by":"publisher","award":["Trent Fund"],"award-info":[{"award-number":["Trent Fund"]}],"id":[{"id":"10.13039\/100006510","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elifesciences.org"],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>\n                    The\n                    <jats:italic>rete ovarii<\/jats:italic>\n                    (RO) is an appendage of the ovary that has been given little attention. Although the RO appears in drawings of the ovary in early versions of Gray\u2019s Anatomy, it disappeared from recent textbooks, and is often dismissed as a functionless vestige in the adult ovary. Using PAX8 immunostaining and confocal microscopy, we characterized the fetal development of the RO in the context of the mouse ovary. The RO consists of three distinct regions that persist in adult life, the intraovarian rete (IOR), the extraovarian rete (EOR), and the connecting rete (CR). While the cells of the IOR appear to form solid cords within the ovary, the EOR rapidly develops into a convoluted tubular epithelium ending in a distal dilated tip. Cells of the EOR are ciliated and exhibit cellular trafficking capabilities. The CR, connecting the EOR to the IOR, gradually acquires tubular epithelial characteristics by birth. Using microinjections into the distal dilated tip of the EOR, we found that luminal contents flow toward the ovary. Mass spectrometry revealed that the EOR lumen contains secreted proteins potentially important for ovarian function. We show that the cells of the EOR are closely associated with vasculature and macrophages, and are contacted by neuronal projections, consistent with a role as a sensory appendage of the ovary. The direct proximity of the RO to the ovary and its integration with the extraovarian landscape suggest that it plays an important role in ovary development and homeostasis.\n                  <\/jats:p>","DOI":"10.7554\/elife.96662","type":"journal-article","created":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T09:25:18Z","timestamp":1716197118000},"update-policy":"https:\/\/doi.org\/10.7554\/elife.96662","source":"Crossref","is-referenced-by-count":2,"title":["Rediscovering the rete ovarii, a secreting auxiliary structure to the ovary"],"prefix":"10.7554","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0435-4749","authenticated-orcid":true,"given":"Dilara N","family":"Anbarci","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00py81415","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Cell Biology, Duke University Medical Center","place":["Durham, United States"]}],"role":[{"role":"author","vocabulary":"crossref"},{"role":"conceptualization","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"},{"role":"visualization","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2640-1502","authenticated-orcid":true,"given":"Jennifer","family":"McKey","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00py81415","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Cell Biology, Duke University Medical Center","place":["Durham, United States"]},{"id":[{"id":"https:\/\/ror.org\/03wmf1y16","id-type":"ROR","asserted-by":"publisher"}],"name":"Section of Developmental Biology, Department of Pediatrics, University of Colorado Anschutz Medical Campus","place":["Aurora, United States"]}],"role":[{"role":"author","vocabulary":"crossref"},{"role":"conceptualization","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"resources","vocabulary":"credit"},{"role":"visualization","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0240-5178","authenticated-orcid":true,"given":"Daniel S","family":"Levic","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00py81415","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Cell Biology, Duke University Medical Center","place":["Durham, United States"]}],"role":[{"role":"author","vocabulary":"crossref"},{"role":"investigation","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3829-0168","authenticated-orcid":true,"given":"Michel","family":"Bagnat","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00py81415","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Cell Biology, Duke University Medical Center","place":["Durham, United States"]}],"role":[{"role":"author","vocabulary":"crossref"},{"role":"funding-acquisition","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"resources","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6587-0969","authenticated-orcid":true,"given":"Blanche","family":"Capel","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00py81415","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Cell Biology, Duke University Medical Center","place":["Durham, United States"]}],"role":[{"role":"author","vocabulary":"crossref"},{"role":"corresponding-author","vocabulary":"crossref"},{"role":"conceptualization","vocabulary":"credit"},{"role":"funding-acquisition","vocabulary":"credit"},{"role":"project-administration","vocabulary":"credit"},{"role":"resources","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]}],"member":"4374","published-online":{"date-parts":[[2025,3,19]]},"reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"198","DOI":"10.4103\/ijmpo.ijmpo_3_17","type":"journal-article","article-title":"Role of insulin-like growth factor, insulin-like growth factor receptors, and insulin-like growth factor-binding proteins in ovarian cancer","volume":"38","author":"Amutha","year":"2017","journal-title":"Indian Journal of Medical and Paediatric Oncology"},{"key":"bib2","doi-asserted-by":"publisher","DOI":"10.1038\/s41597-024-03227-x","type":"journal-article","article-title":"Bulk and single-cell transcriptome datasets of the mouse fetal and adult rete ovarii and surrounding tissues","volume":"11","author":"Anbarci","year":"2024","journal-title":"Scientific Data"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1530\/jrf.0.0260413","type":"journal-article","article-title":"Rete ovarii in heifers: a preliminary study","volume":"26","author":"Archbald","year":"1971","journal-title":"Journal of Reproduction and Fertility"},{"key":"bib4","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1002\/mrd.20174","type":"journal-article","article-title":"Immunolocalization of cubilin, megalin, apolipoprotein J, and apolipoprotein A-I in the uterus and oviduct","volume":"69","author":"Argraves","year":"2004","journal-title":"Molecular Reproduction and Development"},{"key":"bib5","doi-asserted-by":"publisher","first-page":"1503","DOI":"10.1071\/RD17332","type":"journal-article","article-title":"Insulin-like growth factor-1 (IGF-1) promotes primordial follicle growth and reduces DNA fragmentation through the phosphatidylinositol 3-kinase\/protein kinase B (PI3K\/AKT) signalling pathway","volume":"30","author":"Bezerra","year":"2018","journal-title":"Reproduction, Fertility, and Development"},{"key":"bib6","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1172\/JCI78361","type":"journal-article","article-title":"Neuroepithelial circuit formed by innervation of sensory enteroendocrine cells","volume":"125","author":"Boh\u00f3rquez","year":"2015","journal-title":"The Journal of Clinical Investigation"},{"key":"bib7","first-page":"207","type":"journal-article","article-title":"Follicle formation in the immature mouse ovary: the role of the rete ovarii","volume":"116","author":"Byskov","year":"1973","journal-title":"Journal of Anatomy"},{"key":"bib8","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1530\/jrf.0.0450201","type":"journal-article","article-title":"The role of the rete ovarii in meiosis and follicle formation in the cat, mink and ferret","volume":"45","author":"Byskov","year":"1975","journal-title":"Reproduction"},{"key":"bib9","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1590\/S0102-09352000000100012","type":"journal-article","article-title":"Morphological and pathological aspects of the rete ovarii in sheep (Ovis aries)","volume":"52","author":"Cassali","year":"2000","journal-title":"Arquivo Brasileiro de Medicina Veterin\u00e1ria e Zootecnia"},{"key":"bib10","doi-asserted-by":"publisher","first-page":"e47","DOI":"10.1161\/01.RES.0000259564.92792.93","type":"journal-article","article-title":"Angiogenic role of LYVE-1-positive macrophages in adipose tissue","volume":"100","author":"Cho","year":"2007","journal-title":"Circulation Research"},{"key":"bib11","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1073\/pnas.1010299108","type":"journal-article","article-title":"Vascular-mesenchymal cross-talk through Vegf and Pdgf drives organ patterning","volume":"108","author":"Cool","year":"2011","journal-title":"PNAS"},{"key":"bib12","doi-asserted-by":"publisher","first-page":"1446","DOI":"10.1038\/modpathol.2016.153","type":"journal-article","article-title":"Distinct patterns of primary and motile cilia in Rathke\u2019s cleft cysts and craniopharyngioma subtypes","volume":"29","author":"Coy","year":"2016","journal-title":"Modern Pathology"},{"key":"bib13","first-page":"175","type":"journal-article","article-title":"Co-expression of cytokeratin and vimentin filaments in mesothelial, granulosa and rete ovarii cells of the human ovary","volume":"37","author":"Czernobilsky","year":"1985","journal-title":"European Journal of Cell Biology"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"1465","DOI":"10.1152\/physrev.00037.2017","type":"journal-article","article-title":"Endosomal and Phagosomal SNAREs","volume":"98","author":"Dingjan","year":"2018","journal-title":"Physiological Reviews"},{"key":"bib15","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1210\/me.2013-1284","type":"journal-article","article-title":"TGFBR1 is required for mouse myometrial development","volume":"28","author":"Gao","year":"2014","journal-title":"Molecular Endocrinology"},{"key":"bib16","doi-asserted-by":"crossref","DOI":"10.1017\/9781108881760","type":"book","volume-title":"Physiology of the Female Reproductive System, A Textbook of Clinical Embryology","author":"Girsh","year":"2021"},{"key":"bib17","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1007\/978-1-4614-4015-4_5","type":"journal-article","article-title":"Physiological control of germline development","volume":"757","author":"Hubbard","year":"2013","journal-title":"Advances in Experimental Medicine and Biology"},{"key":"bib18","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1165\/rcmb.2009-0328OC","type":"journal-article","article-title":"Temporal relationship between primary and motile ciliogenesis in airway epithelial cells","volume":"43","author":"Jain","year":"2010","journal-title":"American Journal of Respiratory Cell and Molecular Biology"},{"key":"bib19","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1136\/jcp.52.7.517","type":"journal-article","article-title":"Ki-67, oestrogen receptor, and progesterone receptor proteins in the human rete ovarii and in endometriosis","volume":"52","author":"Khan","year":"1999","journal-title":"Journal of Clinical Pathology"},{"key":"bib20","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.1292\/jvms.11-0354","type":"journal-article","article-title":"Bilateral ovarian cysts originating from rete ovarii in an African green monkey (Cercopithecus aethiops)","volume":"74","author":"Kim","year":"2012","journal-title":"The Journal of Veterinary Medical Science"},{"key":"bib21","doi-asserted-by":"publisher","DOI":"10.1101\/2023.08.07.552336","type":"preprint","article-title":"Single-Cell Transcriptome Landscape of Developing Fetal Gonads Defines Somatic Cell Lineage Specification in Humans","volume-title":"bioRxiv","author":"Lardenois","year":"2023"},{"key":"bib22","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1007\/978-3-319-44820-6_3","type":"journal-article","article-title":"Control of germline stem cell lineages by diet and physiology","volume":"59","author":"Laws","year":"2017","journal-title":"Results Probl Cell Differ"},{"key":"bib23","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1111\/j.1469-7580.2011.01431.x","type":"journal-article","article-title":"Ovarian cysts in MRL\u200a\/\u200aMpJ mice are derived from the extraovarian rete: a developmental study","volume":"219","author":"Lee","year":"2011","journal-title":"Journal of Anatomy"},{"key":"bib24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3892\/ijmm.2021.4906","type":"journal-article","article-title":"Estrogen disorders: Interpreting the abnormal regulation of aromatase in granulosa cells (Review)","volume":"47","author":"Liu","year":"2021","journal-title":"International Journal of Molecular Medicine"},{"key":"bib25","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abm0972","type":"journal-article","article-title":"Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad","volume":"8","author":"May\u00e8re","year":"2022","journal-title":"Science Advances"},{"key":"bib26","doi-asserted-by":"publisher","first-page":"5570","DOI":"10.1073\/pnas.1814930116","type":"journal-article","article-title":"Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development","volume":"116","author":"McKey","year":"2019","journal-title":"PNAS"},{"key":"bib27","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.81088","type":"journal-article","article-title":"Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii","volume":"11","author":"McKey","year":"2022","journal-title":"eLife"},{"key":"bib28","doi-asserted-by":"publisher","DOI":"10.1093\/database\/bav077","type":"journal-article","article-title":"MetazSecKB: the human and animal secretome and subcellular proteome knowledgebase","volume":"2015","author":"Meinken","year":"2015","journal-title":"Database"},{"key":"bib29","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1016\/0002-9378(89)90126-9","type":"journal-article","article-title":"A functional and structural study of the innervation of the human uterus","volume":"160","author":"Morizaki","year":"1989","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"bib30","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.111.095208","type":"journal-article","article-title":"Temporal differences in granulosa cell specification in the ovary reflect distinct follicle fates in mice","volume":"86","author":"Mork","year":"2012","journal-title":"Biology of Reproduction"},{"key":"bib31","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1002\/dvg.20335","type":"journal-article","article-title":"A global double-fluorescent Cre reporter mouse","volume":"45","author":"Muzumdar","year":"2007","journal-title":"Genesis"},{"key":"bib32","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1038\/ng1076","type":"journal-article","article-title":"Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells","volume":"33","author":"Nauli","year":"2003","journal-title":"Nature Genetics"},{"key":"bib33","doi-asserted-by":"publisher","first-page":"10482","DOI":"10.1073\/pnas.152238499","type":"journal-article","article-title":"Early restriction of peripheral and proximal cell lineages during formation of the lung","volume":"99","author":"Perl","year":"2002","journal-title":"PNAS"},{"key":"bib34","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/B978-0-12-381361-9.00017-2","type":"journal-article","article-title":"Female reproductive system, Comparative anatomy and histology","volume":"01","author":"Rendi","year":"2012","journal-title":"Elsevier"},{"key":"bib35","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1046\/j.1365-2613.2002.00277.x","type":"journal-article","article-title":"Angiogenesis in the female reproductive organs: pathological implications","volume":"83","author":"Reynolds","year":"2002","journal-title":"International Journal of Experimental Pathology"},{"key":"bib36","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/j.ghir.2004.02.003","type":"journal-article","article-title":"What\u2019s new in the IGF-binding proteins?","volume":"14","author":"Rosenzweig","year":"2004","journal-title":"Growth Hormone & IGF Research"},{"key":"bib37","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1530\/REP-17-0518","type":"journal-article","article-title":"Clusterin in the mouse epididymis: possible roles in sperm maturation and capacitation","volume":"154","author":"Saewu","year":"2017","journal-title":"Reproduction"},{"key":"bib38","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1746-6148-8-235","type":"journal-article","article-title":"Squamous metaplasia of the rete ovarii in a Zebu cow","volume":"8","author":"Santos","year":"2012","journal-title":"BMC Veterinary Research"},{"key":"bib39","doi-asserted-by":"publisher","first-page":"4558","DOI":"10.1242\/dev.115659","type":"journal-article","article-title":"Celsr1 is required for the generation of polarity at multiple levels of the mouse oviduct","volume":"141","author":"Shi","year":"2014","journal-title":"Development"},{"key":"bib40","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1080\/0968768031000104953","type":"journal-article","article-title":"Regulated exocytosis and SNARE function (Review)","volume":"20","author":"S\u00f6llner","year":"2003","journal-title":"Molecular Membrane Biology"},{"key":"bib41","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1002\/ar.1091930203","type":"journal-article","article-title":"A qualitative and quantitative study of rete ovarii development in the fetal rat: correlation with the onset of meiosis and follicle cell appearance","volume":"193","author":"Stein","year":"1979","journal-title":"The Anatomical Record"},{"key":"bib42","doi-asserted-by":"publisher","DOI":"10.1101\/2022.07.20.500903","type":"preprint","article-title":"Characterization of the Human Fetal Rete Region by Single Cell Transcriptional Analysis of Gonads and Mesonephros\/Epididymis","volume-title":"bioRxiv","author":"Taelman","year":"2022"},{"key":"bib43","doi-asserted-by":"publisher","first-page":"4049","DOI":"10.1242\/jcs.102913","type":"journal-article","article-title":"Rab11 regulates exocytosis of recycling vesicles at the plasma membrane","volume":"125","author":"Takahashi","year":"2012","journal-title":"Journal of Cell Science"},{"key":"bib44","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2020.106311","type":"journal-article","article-title":"The insulin-like growth factor system: a target for endocrine disruptors?","volume":"147","author":"Talia","year":"2021","journal-title":"Environment International"},{"key":"bib45","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1038\/nm.1865","type":"journal-article","article-title":"An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice","volume":"14","author":"Traykova-Brauch","year":"2008","journal-title":"Nature Medicine"},{"key":"bib46","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1126\/science.1092436","type":"journal-article","article-title":"Defining the epithelial stem cell niche in skin","volume":"303","author":"Tumbar","year":"2004","journal-title":"Science"},{"key":"bib47","volume-title":"Eierstock un Ei, Ein Beitrag zur Anatomie und Entwicklungsgeschichte der Sexualorgane","author":"Waldeyer","year":"1870","type":"book"},{"key":"bib48","first-page":"411","type":"journal-article","article-title":"The mammalian rete ovarii: a literature review","volume":"75","author":"Wenzel","year":"1985","journal-title":"The Cornell Veterinarian"},{"key":"bib49","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1111\/j.1439-0264.1987.tb00731.x","type":"journal-article","article-title":"Histological and histochemical characterization of the bovine rete ovarii through the estrous cycle and gestation","volume":"16","author":"Wenzel","year":"1987","journal-title":"Anatomia, Histologia, Embryologia"},{"key":"bib50","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1080\/003130200104277","type":"journal-article","article-title":"An immunohistochemical study of the rete ovarii and epoophoron","volume":"32","author":"Woolnough","year":"2000","journal-title":"Pathology"},{"key":"bib51","doi-asserted-by":"publisher","first-page":"920","DOI":"10.1093\/hmg\/ddt486","type":"journal-article","article-title":"Two classes of ovarian primordial follicles exhibit distinct developmental dynamics and physiological functions","volume":"23","author":"Zheng","year":"2014","journal-title":"Human Molecular Genetics"},{"key":"dataset1","type":"dataset","article-title":"Transcriptome analysis of the mouse fetal and adult rete ovarii and surrounding tissues","volume-title":"NCBI Gene Expression Omnibus","author":"Anbarci","year":"2024","unstructured":"Anbarci DN, O'Rourke R, Xiang Y, Peters DT, Capel B, McKey J. 2024. Transcriptome analysis of the mouse fetal and adult rete ovarii and surrounding tissues. NCBI Gene Expression Omnibus. https:\/\/www.ncbi.nlm.nih.gov\/geo\/query\/acc.cgi?acc=GSE244849. GSE244849."}],"container-title":["eLife"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/cdn.elifesciences.org\/articles\/96662\/elife-96662-v1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/cdn.elifesciences.org\/articles\/96662\/elife-96662-v1.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/elifesciences.org\/articles\/96662","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T09:48:02Z","timestamp":1787564882000},"score":1,"resource":{"primary":{"URL":"https:\/\/elifesciences.org\/articles\/96662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,19]]},"references-count":52,"alternative-id":["10.7554\/eLife.96662"],"URL":"https:\/\/doi.org\/10.7554\/elife.96662","archive":["CLOCKSS"],"relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2023.11.08.566085","asserted-by":"subject"},{"id-type":"doi","id":"10.1101\/2023.11.08.566085","asserted-by":"object"}],"references":[{"id-type":"accession","id":"GSE244849","asserted-by":"subject"}],"is-same-as":[{"id-type":"doi","id":"10.7554\/eLife.96662.3","asserted-by":"subject"}],"is-version-of":[{"id-type":"doi","id":"10.7554\/eLife.96662.1","asserted-by":"subject"},{"id-type":"doi","id":"10.7554\/eLife.96662.2","asserted-by":"subject"}]},"ISSN":["2050-084X"],"issn-type":[{"value":"2050-084X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,19]]},"assertion":[{"value":"single anonymised","name":"peer_review_transparency","label":"Peer review transparency","group":{"name":"peer_review_taxonomy"}},{"value":"other reviewer(s), editor","name":"peer_review_interaction","label":"Peer review interaction","group":{"name":"peer_review_taxonomy"}},{"value":"review summaries, review reports, author\/editor communication, reviewer identities reviewer opt in, editor identities","name":"peer_review_published","label":"Peer review published","group":{"name":"peer_review_taxonomy"}},{"value":"open (sign in with ORCID iD required)","name":"post_publication_commenting","label":"Post publication commenting","group":{"name":"post_publication_commenting"}}],"article-number":"RP96662"}}