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Although it is not part of the diagnostic criteria, hearing difficulties ranging from deafness to hyperacusis are present in the majority of persons with ASD. High-functioning children with ASD have been found to have significantly slower and asymmetric auditory brainstem reflexes. Additionally, histopathological studies of postmortem brainstems in decedents who had ASD have consistently revealed significantly fewer neurons in auditory nuclei compared with those in people who did not have ASD. The authors review the literature implicating auditory dysfunction in ASD along with results from human study participants and postmortem human brain tissue. Together, these results implicate significant structural and functional abnormalities in the auditory brainstem in ASD and support the utility of auditory testing to screen for ASD.<\/jats:p>","DOI":"10.7556\/jaoa.2019.007","type":"journal-article","created":{"date-parts":[[2019,1,9]],"date-time":"2019-01-09T10:50:28Z","timestamp":1547031028000},"page":"41-50","source":"Crossref","is-referenced-by-count":20,"title":["Structural and Functional Aberrations of the Auditory Brainstem in Autism Spectrum Disorder"],"prefix":"10.1515","volume":"119","author":[{"given":"Amanda","family":"Smith","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha","family":"Storti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Lukose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randy J.","family":"Kulesza Jr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2019,1,1]]},"reference":[{"issue":"1-2","key":"2022022617382917839_j_jaoa.2019.007_ref_001","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.heares.2006.12.006","article-title":"Cytoarchitecture of the human superior olivary complex: medial and lateral superior olive","volume":"225","author":"Jr","year":"2007","journal-title":"Hear Res"},{"key":"2022022617382917839_j_jaoa.2019.007_ref_002","first-page":"43","article-title":"Structural organization of the descending auditory pathway","volume-title":"The Oxford Handbook of Auditory Science: Auditory Brain.","author":"Schofield","year":"2010"},{"issue":"1","key":"2022022617382917839_j_jaoa.2019.007_ref_003","first-page":"101","article-title":"On the neuronal organization of the acoustic middle ear reflex","volume":"49","author":"Borg","year":"1973","journal-title":"A physiological and anatomical study. 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