{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:09:17Z","timestamp":1777489757715,"version":"3.51.4"},"reference-count":15,"publisher":"Walter de Gruyter GmbH","issue":"7","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jaoa.2019.084_s_001\">\n                  <jats:title>Context<\/jats:title>\n                  <jats:p>Cystic fibrosis (CF) is an autosomal recessive genetic disorder primarily affecting the lungs and digestive system. Patients with CF often have multiorgan dysfunction, including chronic lung infections, pancreatic insufficiency, chronic constipation, and distal intestinal obstructive syndrome (DIOS).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jaoa.2019.084_s_002\">\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To understand the impact of osteopathic manipulative treatment (OMT) on the prevention and management of gastrointestinal symptoms in patients with CF.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jaoa.2019.084_s_003\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This study used OMT for physical manipulation of the viscera, spine, and other somatic components to improve bowel symptoms and prevent DIOS. These effects were achieved by releasing myofascial restrictions found in the abdomen and somatic structures with the intent to optimize the autonomic and lymphatic systems and improve range of motion.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jaoa.2019.084_s_004\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Four of 5 participants had a decrease in pain, and 3 participants had a reduced need for laxatives during treatment. Four participants had an overall increase in satisfaction with their bowel movements while being treated with OMT.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jaoa.2019.084_s_005\">\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>These findings support the use of OMT as a method for the management of chronic constipation and DIOS in the CF population. However, because of the small population size, more research with larger populations is needed.<\/jats:p>\n               <\/jats:sec>","DOI":"10.7556\/jaoa.2019.084","type":"journal-article","created":{"date-parts":[[2019,6,24]],"date-time":"2019-06-24T23:34:00Z","timestamp":1561419240000},"page":"e31-e35","source":"Crossref","is-referenced-by-count":8,"title":["OMT for the Prevention and Management of Chronic Constipation and Distal Intestinal Obstructive Syndrome in Cystic Fibrosis: A Pilot Study"],"prefix":"10.1515","volume":"119","author":[{"given":"Sara E.","family":"Modlin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristian","family":"Borofka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle","family":"Franzini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alaina C.","family":"Klene-Bowns","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor A.","family":"Nu\u00f1o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2019,7,1]]},"reference":[{"key":"2022022617060417532_j_jaoa.2019.084_ref_001","unstructured":"Patient Registry Annual Data Report 2015. 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