{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T10:30:06Z","timestamp":1793442606390,"version":"4.5.0"},"reference-count":24,"publisher":"Wildlife Disease Association","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Wildlife Diseases"],"published-print":{"date-parts":[[2021,3,25]]},"abstract":"<jats:p>Paratuberculosis (PTB) is a disease that affects cattle (Bos taurus), goats (Capra aegagrus hircus), sheep (Ovis aries), and wild animals, such as white-tailed deer (Odocoileus virginianus), since all ruminants are susceptible. The causal agent is Mycobacterium avium subsp. paratuberculosis (MAP). The disease is chronic, consumptive, and incurable; it causes chronic granulomatous gastroenteritis with lymphangiectasis and lymphangitis leading to a syndrome of malnutrition and eventually to death. Mycobacterium avium subsp. paratuberculosis is transmitted in feces mainly orally; however, it can also be transmitted vertically. Thus, the objective of this study was to determine the seroprevalence of MAP antibodies and its relationship to age and sex of Texas white-tailed deer in the subclinical stage of PTB in Coahuila, Mexico. The entire population (n=99) belonging to the Wildlife Management and Conservation Unit (WMCU) San Juan, Monclova, Coahuila, Mexico was captured. Mycobacterium avium subsp. paratuberculosis was diagnosed using an enzyme-linked immunosorbent assay by serologic test. Seroprevalence variables of adult vs. young females and males vs. females were compared. The treatments were assigned at random. For the analysis of data, the chi-square test was used. Total seroprevalence in an intensive WMCU was 16% (16\/99). Total seroprevalence by sex was 5.0% (5\/99) for males and 11% (11\/99) for females, and total seroprevalence by age was 7% (7\/99) for young and 9% (9\/99) for adult. Within sex, the seroprevalence in males was 16% (5\/31) and 16% (11\/68) in females. There were no statistical differences for any of the comparisons. Total seroprevalence of the white-tailed deer population in the WMCU was 16%, and PTB seroprevalence was independent of sex or age of the sampled individuals of this population.<\/jats:p>","DOI":"10.7589\/jwd-d-20-00045","type":"journal-article","created":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T12:02:20Z","timestamp":1616673740000},"page":"321-326","source":"Crossref","is-referenced-by-count":0,"title":["SEROPREVALENCE OF ANTIBODIES AGAINST MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS AND ITS RELATIONSHIP TO AGE AND SEX OF TEXAS WHITE-TAILED DEER (ODOCOILEUS VIRGINIANUS) IN COAHUILA, MEXICO"],"prefix":"10.7589","volume":"57","author":[{"given":"E. Alejandro","family":"Lozano-Cavazos","sequence":"first","affiliation":[{"name":"Departamento de Recursos Naturales Renovables, Universidad Aut\u00f3noma Agraria Antonio Narro, Saltillo, Coahuila, Mexico, 25315."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Vicente","family":"Vel\u00e1zquez-Morales","sequence":"additional","affiliation":[{"name":"Programa de Ganader\u00eda, Campus Montecillo, Colegio de Postgraduados (ColPos), Km 36.5 Carretera M\u00e9xico-Texcoco, Montecillo, Texcoco, Mexico, 56230."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco A.","family":"Santill\u00e1n-Flores","sequence":"additional","affiliation":[{"name":"Centro Nacional de Investigaci\u00f3n Disciplinaria en Microbiolog\u00eda Animal (CENID-Microbiolog\u00eda), Instituto Nacional de Investigaciones Forestales, Agr\u00edcolas y Pecuarias (INIFAP), Km. 15.5 Carretera M\u00e9xico-Toluca, Palo Alto, Cuajimalpa, Mexico, 05110."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis A.","family":"Tarango-Ar\u00e1mbula","sequence":"additional","affiliation":[{"name":"Posgrado en Innovaci\u00f3n en Manejo de Recursos Naturales, Campus SLP, Colegio de Postgraduados (ColPos), Iturbide 73, Salinas de Hidalgo, San Luis Potos\u00ed, Mexico, 78600."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genaro","family":"Olmos-Oropeza","sequence":"additional","affiliation":[{"name":"Posgrado en Innovaci\u00f3n en Manejo de Recursos Naturales, Campus SLP, Colegio de Postgraduados (ColPos), Iturbide 73, Salinas de Hidalgo, San Luis Potos\u00ed, Mexico, 78600."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Felipe","family":"Mart\u00ednez-Montoya","sequence":"additional","affiliation":[{"name":"Posgrado en Innovaci\u00f3n en Manejo de Recursos Naturales, Campus SLP, Colegio de Postgraduados (ColPos), Iturbide 73, Salinas de Hidalgo, San Luis Potos\u00ed, Mexico, 78600."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9sar","family":"Cortez-Romero","sequence":"additional","affiliation":[{"name":"Programa de Ganader\u00eda, Campus Montecillo, Colegio de Postgraduados (ColPos), Km 36.5 Carretera M\u00e9xico-Texcoco, Montecillo, Texcoco, Mexico, 56230."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4415","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"T Carta, J \u00c1lvarez,  P\u00e9rez de la Lastra, et al.  \"Res Vet Sci.\"  94, \"Wildlife and paratuberculosis: A review.\" 191 (2013)","DOI":"10.1016\/j.rvsc.2012.11.002"},{"key":"2","unstructured":"RJ Chiodini, HJ Van Kruiningen, RS Merkal,  \"Cornell Vet.\"  74, \"Ruminant paratuberculosis (Johne's disease): The current status and future prospects.\" 218 (1984)"},{"key":"3","doi-asserted-by":"crossref","unstructured":"P Corti, B Collado, C Riquelme, et al.  \"Austral J Vet Sci.\"  52, \"Mycobacterium avium subsp. paratuberculosis (MAP) infection in the endangered huemul deer (Hippocamelus bisulcus) in Patagonia.\" 33 (2020)","DOI":"10.4067\/S0719-81322020000100106"},{"key":"4","unstructured":"E. Garc\u00eda,  \"Modificaciones al sistema de clasificaci\u00f3n clim\u00e1tica de K\u00f6ppen. Serie Libros, n\u00fam. 6.\"  , 91 (2004)"},{"key":"5","doi-asserted-by":"crossref","unstructured":"HL Hattel, DP Shaw, BC Love, et al.  \"J Vet Diagn Invest.\"  16, \"A retrospective study of mortality in Pennsylvania captive white-tailed deer (Odocoileus virginianus): 2000\u20132003.\" 515 (2004)","DOI":"10.1177\/104063870401600605"},{"key":"6","unstructured":"et al.  \"Uso del suelo y vegetaci\u00f3n, escala 1:250000, Serie I (Continuo Nacional). Cat\u00e1logo de metadatos geogr\u00e1ficos. Comisi\u00f3n Nacional para el Conocimiento y Uso de la Biodiversidad (CONABIO).\"  ,  (1997)"},{"key":"7","unstructured":"et al.  \"Conjunto de datos vectoriales edafol\u00f3gico, escala 1:250000, Serie II (Continuo Nacional). Escala: 1:250000. Edici\u00f3n 2.\"  ,  (2014)"},{"key":"8","unstructured":"GN Jaimes, MA Santill\u00e1n Flores, OA Hern\u00e1ndez Cortez, et al.  \"Vet M\u00e9x.\"  39, \"Detecci\u00f3n de Mycobacterium avium subespecie paratuberculosis, por medio de PCR-anidada a partir de muestras de heces de ovinos.\" 377 (2008)"},{"key":"9","doi-asserted-by":"crossref","unstructured":"JL Khol, P Kralik, I Slana, et al.  \"J Vet Med Sci.\"  72, \"Consecutive excretion of Mycobacterium avium subspecies paratuberculosis in semen of a breeding bull compared to the distribution in feces, tissue and blood by IS900 and F57 quantitative real-time PCR and culture examinations.\" 1283 (2010)","DOI":"10.1292\/jvms.10-0052"},{"key":"10","doi-asserted-by":"crossref","unstructured":"M Kopecna, I Parmova, L Dvorska-Bartosova, et al.  \"Vet Med.\"  53, \"Distribution and transmission of Mycobacterium avium subspecies paratuberculosis in farmed red deer (Cervus elaphus) studied by faecal culture, serology and IS900 RFLP examinations.\" 510 (2008)","DOI":"10.17221\/1980-VETMED"},{"key":"11","doi-asserted-by":"crossref","unstructured":"CG Mackintosh, RG Clark, B Thompson, et al.  \"Vet Microbiol.\"  143, \"Age susceptibility of red deer (Cervus elaphus) to paratuberculosis.\" 255 (2010)","DOI":"10.1016\/j.vetmic.2009.11.014"},{"key":"12","unstructured":"LE Maderey-Rasc\u00f3n  and C Torres-Ruata  \"Hidrograf\u00eda. Extra\u00eddo de hidrograf\u00eda e hidrometr\u00eda, IV.6.1 (A). Atlas Nacional de M\u00e9xico. Vol. II. Escala 1: 4000000.\"  ,  (1990)"},{"key":"13","doi-asserted-by":"crossref","unstructured":"S. Mandujano,  \"Acta Zool Mex.\"  20, \"An\u00e1lisis bibliogr\u00e1fico de los estudios de venados en M\u00e9xico.\" 211 (2004)","DOI":"10.21829\/azm.2004.2012536"},{"key":"14","unstructured":"AG Mart\u00ednez Covarrubias, MA Santill\u00e1n Flores, CC Guzm\u00e1n Ruiz, et al.  \"Rev Mex Cienc Pec.\"  3, \"Desarrollo de un inmuno-ensayo enzim\u00e1tico (ELISA) para el diagn\u00f3stico de paratuberculosis en bovinos.\" 1 (2012)"},{"key":"15","doi-asserted-by":"crossref","unstructured":"MV Palmer, C Kanipe, R Cox, et al.  \"J Vet Diagn Invest.\"  31, \"Characteristics of subclinical Mycobacterium avium ssp. paratuberculosis infection in a captive white-tailed deer herd.\" 844 (2019)","DOI":"10.1177\/1040638719873028"},{"key":"16","doi-asserted-by":"crossref","unstructured":"CF Quist, VF Nettles, EJB Manning, et al.  \"J Wildl Dis.\"  38, \"Paratuberculosis in key deer (Odocoileus virginianus clavium).\" 729 (2002)","DOI":"10.7589\/0090-3558-38.4.729"},{"key":"17","doi-asserted-by":"crossref","unstructured":"L Rindi  and C Garzelli  \"Infect Genet Evol.\"  21, \"Genetic diversity and phylogeny of Mycobacterium avium.\" 375 (2014)","DOI":"10.1016\/j.meegid.2013.12.007"},{"key":"18","doi-asserted-by":"crossref","unstructured":"JM Sleeman, EJB Manning, JH Rohm, et al.  \"J Wildl Dis.\"  45, \"Johne's disease in a free-ranging white-tailed deer from Virginia and subsequent surveillance for Mycobacterium avium subspecies paratuberculosis.\" 201 (2009)","DOI":"10.7589\/0090-3558-45.1.201"},{"key":"19","doi-asserted-by":"crossref","unstructured":"A Stau, B Seelig, D Walter, et al.  \"Small Rumin Res.\"  105, \"Seroprevalence of Mycobacterium avium subsp. paratuberculosis in small ruminants in Germany.\" 361 (2012)","DOI":"10.1016\/j.smallrumres.2012.03.008"},{"key":"20","doi-asserted-by":"crossref","unstructured":"JV Vel\u00e1zquez-Morales, MA Santill\u00e1n-Flores, J Gallegos-S\u00e1nchez, et al.  \"Animal Reprod.\"  16, \"Detection of Mycobacterium avium subsp. paratuberculosis in reproductive tissue and semen of naturally infected rams.\" 930 (2019)","DOI":"10.21451\/1984-3143-AR2018-0147"},{"key":"21","doi-asserted-by":"crossref","unstructured":"RJ Whittington, DJ Begg, K De Silva, et al.  \"Vet Immunol Immunopathol.\"  148, \"Comparative immunological and microbiological aspects of paratuberculosis as a model mycobacterial infection.\" 29 (2012)","DOI":"10.1016\/j.vetimm.2011.03.003"},{"key":"22","doi-asserted-by":"crossref","unstructured":"PA Windsor  and RJ Whittington  \"Vet J.\"  184, \"Evidence for age susceptibility of cattle to Johne's disease.\" 37 (2010)","DOI":"10.1016\/j.tvjl.2009.01.007"},{"key":"23","doi-asserted-by":"crossref","unstructured":"KN Wolf, CS DePerno, JA Jenks, et al.  \"J Wildl Dis.\"  44, \"Selenium status and antibodies to selected pathogens in white-tailed deer (Odocoileus virginianus) in southern Minnesota.\" 181 (2008)","DOI":"10.7589\/0090-3558-44.1.181"},{"key":"24","unstructured":"MR Woodbury, M Chirino-Trejo, B Mihajlovic,  \"Can Vet J.\"  49, \"Diagnostic detection methods for Mycobacterium avium subsp. paratuberculosis in white-tailed deer.\" 683 (2008)"}],"container-title":["Journal of Wildlife Diseases"],"original-title":[],"deposited":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T09:32:00Z","timestamp":1793439120000},"score":1,"resource":{"primary":{"URL":"https:\/\/bioone.org\/journals\/journal-of-wildlife-diseases\/volume-57\/issue-2\/JWD-D-20-00045\/SEROPREVALENCE-OF-ANTIBODIES-AGAINST-MYCOBACTERIUM-AVIUM-SUBSP-PARATUBERCULOSIS-AND-ITS\/10.7589\/JWD-D-20-00045.full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,25]]},"references-count":24,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,4,1]]}},"URL":"https:\/\/doi.org\/10.7589\/jwd-d-20-00045","relation":{},"ISSN":["0090-3558","1943-3700"],"issn-type":[{"value":"0090-3558","type":"print"},{"value":"1943-3700","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,25]]}}}