{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T07:32:02Z","timestamp":1793431922024,"version":"4.5.0"},"reference-count":7,"publisher":"Wildlife Disease Association","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Wildlife Diseases"],"published-print":{"date-parts":[[2022,7,25]]},"abstract":"<jats:p>During necropsy of two manatees, masses in multiple organs including liver and spleen were identified. They were composed of neoplastic round to spindle-shaped cells, positive for vimentin, Iba-1, lysozyme, and Mac387, consistent with histiocytic sarcoma. One manatee also had an undifferentiated sarcoma that may have arisen from the histiocytic sarcoma.<\/jats:p>","DOI":"10.7589\/jwd-d-21-00138","type":"journal-article","created":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T06:59:36Z","timestamp":1658732376000},"page":"685-688","source":"Crossref","is-referenced-by-count":3,"title":["Disseminated Histiocytic Sarcoma in Two Free-Living Florida Manatees (Trichechus manatus latirostris)"],"prefix":"10.7589","volume":"58","author":[{"given":"David S.","family":"Rotstein","sequence":"first","affiliation":[{"name":"Marine Mammal Pathology Services, 19117 Bloomfield Road, Olney, Maryland 20832, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole I.","family":"Stacy","sequence":"additional","affiliation":[{"name":"Department of Comparative, Diagnostic, and Population Medicine, College of Veterinary Medicine, University of Florida, 2015 SW 16th Avenue, Gainesville, Florida 32608, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Kinsel","sequence":"additional","affiliation":[{"name":"Zoological Pathology Program, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, 3300 Golf Road, Maywood, Illinois 60153, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martine","family":"de Wit","sequence":"additional","affiliation":[{"name":"Fish and Wildlife Research Institute, Florida Fish and Wildlife Conservation Commission, 100 8th Avenue SE, St. Petersburg, Florida 33701, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4415","reference":[{"key":"4","doi-asserted-by":"crossref","unstructured":"PF. Moore,  \"Vet Pathol.\"  51, \"A review of histiocytic diseases of dogs and cats.\" 167 (2014)","DOI":"10.1177\/0300985813510413"},{"key":"2","doi-asserted-by":"crossref","unstructured":"LJ Flewelling, JP Naar, JP Abbott, et al.  \"Nature.\"  435, \"Brevetoxicosis: red tides and marine mammal mortalities.\" 755 (2005)","DOI":"10.1038\/nature435755a"},{"key":"1","doi-asserted-by":"crossref","unstructured":"GD Bossart, RY Ewing, M Lowe, et al.  \"Exp Mol Pathol.\"  72, \"Viral papillomatosis in Florida manatees (Trichechus manatus latirostris).\" 37 (2002)","DOI":"10.1006\/exmp.2001.2407"},{"key":"3","doi-asserted-by":"crossref","unstructured":"AS Hammer, B Klausen, S Knold, et al.  \"J Wildl Dis.\"  41, \"Malignant lymphoma in a West Indian manatee (Trichechus manatus).\" 834 (2005)","DOI":"10.7589\/0090-3558-41.4.834"},{"key":"5","doi-asserted-by":"crossref","unstructured":"K Ogihara, T Itoh, Y Mizuno, et al.  \"J Comp Pathol.\"  155, \"Disseminated histiocytic sarcoma in an African hedgehog (Atelerix albiventris).\" 361 (2016)","DOI":"10.1016\/j.jcpa.2016.09.001"},{"key":"6","doi-asserted-by":"crossref","unstructured":"LN Smith, DS Rotstein, RL Ball, et al.  \"J Zoo Wildl Med.\"  46, \"Reproductive neoplasms in wild and long-term captive female Florida manatees (Trichechus manatus latirostris).\" 895 (2015)","DOI":"10.1638\/2014-0195.1"},{"key":"7","doi-asserted-by":"crossref","unstructured":"A Thongtharb, K Uchida, JK Chambers, et al.  \"J Vet Diagn Invest.\"  28, \"Histological and immunohistochemical features of histiocytic sarcoma in four domestic ferrets (Mustela putorius furo).\" 165 (2016)","DOI":"10.1177\/1040638715626485"}],"container-title":["Journal of Wildlife Diseases"],"original-title":[],"deposited":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T07:04:42Z","timestamp":1793430282000},"score":1,"resource":{"primary":{"URL":"https:\/\/bioone.org\/journals\/journal-of-wildlife-diseases\/volume-58\/issue-3\/JWD-D-21-00138\/Disseminated-Histiocytic-Sarcoma-in-Two-Free-Living-Florida-Manatees-Trichechus\/10.7589\/JWD-D-21-00138.full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,25]]},"references-count":7,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2022,7,1]]}},"URL":"https:\/\/doi.org\/10.7589\/jwd-d-21-00138","relation":{},"ISSN":["0090-3558","1943-3700"],"issn-type":[{"value":"0090-3558","type":"print"},{"value":"1943-3700","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,25]]}}}