{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T17:35:18Z","timestamp":1793900118017,"version":"4.8.0"},"reference-count":20,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"4","content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["biomedica"],"abstract":"<jats:p>Introduccci\u00f3n. La apendicitis aguda es la primera causa de abdomen agudo; sin embargo, poco se conoce sobre las bacterias asociadas y su perfil de sensibilidad.Objetivo. Identificar y determinar el patr\u00f3n de resistencia de las bacterias aerobias y anaerobias aisladas en cultivo de l\u00edquido periapendicular tomado de los pacientes con apendicitis aguda, y establecer la proporci\u00f3n de bacterias seg\u00fan la fase cl\u00ednica. Materiales y m\u00e9todos. Se llev\u00f3 a cabo un estudio descriptivo y prospectivo en el Hospital Universitario de San Jos\u00e9 de Bogot\u00e1 (Colombia), en pacientes mayores de 16 a\u00f1os sometidos a apendicectom\u00eda abierta. Se tomaron muestras de l\u00edquido periapendicular, las cuales se sembraron directamente en botellas de hemocultivos para aerobios y anaerobios.Resultados. Se incluyeron 154 pacientes. Del total de cultivos, el 87 % (n=134) fueron positivos: 77 % (n=118) para aerobios y 51 % (n=79) para anaerobios. La proporci\u00f3n de cultivos positivos fue inferior en los casos de apendicitis no complicada, en comparaci\u00f3n con aquellos de apendicitis complicada (80 % (66\/83) Vs. 95 % (67\/71); p=0,003). Los microorganismos aislados con mayor frecuencia fueron: Escherichia coli (53 %) (n=84), Bacteroides sp. (25 %) (n=25), Propionibacterium acnes (21 %) (n=21), Staphylococci coagulasa negativo (17 %) (n=27), Enterococcus sp. (10 %) (n=15) y Fusobacterium sp. (11 %) (n=11). La sensibilidad de E. coli a la amplicilina sulbactam fue de 30 %. La sensibilidad de Bacteroides spp. a la clindamicina y la ampicilina sulbactam fue de 91 %. El 100 % de los anaerobios fueron sensibles a piperacilina tazobactam, ertapenem, meropenem y metronidazol.Conclusiones. Los cultivos intraoperatorios son pertinentes en la apendicitis para determinar el patr\u00f3n epidemiol\u00f3gico local, y establecer los antibi\u00f3ticos profil\u00e1cticos y terap\u00e9uticos para esta enfermedad. Su siembra directa en botellas de hemocultivo permite una gran recuperaci\u00f3n de microorganismos.<\/jats:p>","DOI":"10.7705\/biomedica.4774","type":"journal-article","created":{"date-parts":[[2019,12,10]],"date-time":"2019-12-10T08:33:08Z","timestamp":1575966788000},"page":"699-706","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":9,"title":["Recuperaci\u00f3n de bacterias aerobias y anaerobias de pacientes con apendicitis aguda mediante botellas de hemocultivo"],"prefix":"10.7705","volume":"39","author":[{"given":"Adriana","family":"Jim\u00e9nez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9s","family":"S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9s","family":"Rey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Fajardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4444","published-online":{"date-parts":[[2019,12,1]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Flum D. 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