{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T22:49:48Z","timestamp":1648766988304},"reference-count":33,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"Supl. 1","content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["biomedica"],"abstract":"<jats:p>Introducci\u00f3n. Staphylococcus aureus resistente a la meticilina (SARM) es un microorganismo que coloniza las fosas nasales y diferentes partes del cuerpo, lo cual se considera un factor de riesgo para adquirir infecciones invasivas, especialmente en pacientes sometidos a cirug\u00eda cardiovascular.Objetivo. Determinar la colonizaci\u00f3n nasal por SARM y establecer las caracter\u00edsticas cl\u00ednicas en pacientes programados para cirug\u00eda cardiovascular.Materiales y m\u00e9todos. Se hizo un estudio descriptivo entre febrero y diciembre de 2015. Se incluyeron pacientes adultos programados para cirug\u00eda cardiovascular en el Hospital Universitario San Ignacio de Bogot\u00e1. La colonizaci\u00f3n se identific\u00f3 mediante reacci\u00f3n en cadena de la polimerasa (Polymerase Chain Reaction, PCR) en tiempo real en muestras obtenidas mediante hisopados nasales. Los pacientes fueron descolonizados con mupirocina al 2,0 % intranasal dos veces al d\u00eda y ba\u00f1os con gluconato de clorhexidina al 4 % del cuello hac\u00eda abajo durante cinco d\u00edas, al cabo de lo cual se hizo una PCR de control.Resultados. Se incluyeron 141 pacientes, 52 hospitalizados y 89 ambulatorios. Del total, 19 (13,4 %) ten\u00edan colonizaci\u00f3n nasal por SARM, correspondientes a 9 (17,3 %) de los 52 hospitalizados y 10 (11,2 %) de los 89 ambulatorios. Todos los pacientes sometidos a descolonizaci\u00f3n tuvieron resultado negativo en la PCR al final del proceso y ninguno present\u00f3 infecci\u00f3n del sitio operatorio por S. aureus.Conclusiones. Se demostr\u00f3 colonizaci\u00f3n nasal por SARM tanto en los pacientes hospitalizados como en los ambulatorios. La descolonizaci\u00f3n con mupirocina fue efectiva para erradicar el estado de portador a corto plazo, lo que podr\u00eda tener efecto en las tasas de infecci\u00f3n del sitio operatorio en las cirug\u00edas cardiovasculares.<\/jats:p>","DOI":"10.7705\/biomedica.4791","type":"journal-article","created":{"date-parts":[[2020,5,27]],"date-time":"2020-05-27T21:32:34Z","timestamp":1590615154000},"page":"37-44","update-policy":"http:\/\/dx.doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":0,"title":["Colonizaci\u00f3n nasal por Staphylococcus aureus resistente a la meticilina en pacientes sometidos a cirug\u00eda cardiovascular en un hospital universitario de Bogot\u00e1, Colombia"],"prefix":"10.7705","volume":"40","author":[{"given":"Heidy C.","family":"Mart\u00ednez-D\u00edaz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra L.","family":"Valderrama-Beltr\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana C.","family":"Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia K.","family":"Pinedo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan R.","family":"Correa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c9dgar G.","family":"R\u00edos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie J.","family":"Rojas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yessica Y.","family":"Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marylin","family":"Hidalgo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4444","published-online":{"date-parts":[[2020,5,1]]},"reference":[{"key":"97402","unstructured":"Wertheim HF, Melles DC, Vos MC, van Leeuwen W, van Belkum A, Verbrugh H, et al. 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