{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T14:23:35Z","timestamp":1747232615754,"version":"3.40.5"},"reference-count":16,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"2","content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["biomedica"],"abstract":"<jats:p>La nefropat\u00eda full house se refiere a la detecci\u00f3n simult\u00e1nea de dep\u00f3sitos de IgA, IgG, IgM, C3 y C1q en la inmunofluorescencia, lo que generalmente indica la presencia de nefritis l\u00fapica. Hay pacientes con este patr\u00f3n de inmunofluorescencia, pero con serolog\u00eda negativa para autoanticuerpos, por lo que no se les puede diagnosticar un lupus eritematoso sist\u00e9mico. Este tipo de nefropat\u00eda, en la que no se presentan otros criterios para lupus, se denomina nefropat\u00eda full house no l\u00fapica.En esta presentaci\u00f3n, se describen dos casos: un paciente que ingres\u00f3 con una glomerulonefritis r\u00e1pidamente progresiva y una paciente con s\u00edndrome nefr\u00f3tico, ambos con serolog\u00eda negativa para autoanticuerpos, hallazgos en la biopsia renal indicativos de nefritis l\u00fapica de clase IV y un patr\u00f3n full house en la inmunofluorescencia. La nefropat\u00eda full house no l\u00fapica tiene rasgos histol\u00f3gicos similares a los de la nefritis l\u00fapica y, probablemente, sus bases fisiopatol\u00f3gicas son parecidas. Sin embargo, se necesitan estudios prospectivos para conocer los factores de riesgo y el pron\u00f3stico renal, y poder hacer sugerencias sobre tratamientos espec\u00edficos.<\/jats:p>","DOI":"10.7705\/biomedica.4863","type":"journal-article","created":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T15:00:07Z","timestamp":1594738807000},"page":"220-227","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":0,"title":["Nefropat\u00eda full house no l\u00fapica en pediatr\u00eda: reporte de dos casos"],"prefix":"10.7705","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1253-4934","authenticated-orcid":false,"given":"Gustavo Adolfo","family":"Guerrero","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9135-5186","authenticated-orcid":false,"given":"Luis Francisco","family":"Guerrero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1947-4893","authenticated-orcid":false,"given":"Tatiana","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4444","published-online":{"date-parts":[[2020,6,15]]},"reference":[{"key":"98163","doi-asserted-by":"crossref","unstructured":"Cameron JS. 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Nephrol Dial Transplant. 2004;19:1420-6. https:\/\/doi.org\/10.1093\/ndt\/gfh139","DOI":"10.1093\/ndt\/gfh139"},{"key":"98170","doi-asserted-by":"crossref","unstructured":"Baskin E, Agras PI, Menekse N, Ozdemir H, Cengiz N. Full-house nephropathy in a patient with negative serology for lupus. Rheumatol Int. 2007;27:281-4. https:\/\/doi.org\/10.1007\/s00296-006-0198-0","DOI":"10.1007\/s00296-006-0198-0"},{"key":"98171","doi-asserted-by":"crossref","unstructured":"Lai FM, To KF, Wang AY, Choi PC, Szeto CC, Li PK, et al. Hepatitis B virus-related nephropathy and lupus nephritis: Morphologic similarities of two clinical entities. Mod Pathol. 2000;13:166-72. https:\/\/doi.org\/10.1038\/modpathol.3880031","DOI":"10.1038\/modpathol.3880031"},{"key":"98172","doi-asserted-by":"crossref","unstructured":"Mart\u00edn ML, Mu\u00f1oz C, Eraso R, Vel\u00e1squez MP, Arias LF. Nefropat\u00eda \u201cfull house\u201d no l\u00fapica, aspectos cl\u00ednicos e histol\u00f3gicos. Experiencia en dos centros hospitalarios de Medell\u00edn, Colombia. Revista Colombiana de Reumatolog\u00eda. 2012;19:124-30.","DOI":"10.1016\/S0121-8123(12)70021-X"},{"key":"98173","doi-asserted-by":"crossref","unstructured":"Rijnink EC, Teng YK, Kraaij T, Wolterbeek R, Bruijn JA, Bajema IM. Idiopathic non-lupus full-house nephropathy is associated with poor renal outcome. Nephrol Dial Transplant. 2017;32:654-62. https:\/\/doi.org\/10.1093\/ndt\/gfx020","DOI":"10.1093\/ndt\/gfx020"},{"key":"98174","doi-asserted-by":"crossref","unstructured":"Ruggiero B, Vivarelli M, Gianviti A, Pecoraro C, Peruzzi L, Benetti E, et al. Outcome of childhood-onset full-house nephropathy. Nephrol Dial Transplant. 2017;32:1194-204. https:\/\/doi.org\/10.1093\/ndt\/gfw230","DOI":"10.1093\/ndt\/gfw230"},{"key":"98175","doi-asserted-by":"crossref","unstructured":"L\u2019Erario I, Frezzolini A, Ruggiero B, De Pit\u00e0 O, Emma F, Gianviti A. 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