{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T11:17:33Z","timestamp":1762341453047,"version":"3.37.3"},"reference-count":14,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"Supl. 1","content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["biomedica"],"abstract":"<jats:p>Strongyloides stercoralis hyperinfection syndrome is a medical emergency that requires a high level of suspicion. Immunocompromised patients are at high risk of hyperinfection syndrome; however, malnutrition, alcoholism, and diabetes mellitus also need to be considered as predisposing factors. The diagnosis and treatment of Strongyloides hyperinfection are challenging and patients often have severe complications. Consequently, mortality is overwhelmingly high, with proportions above 60%.Herein, we report a case of Strongyloides hyperinfection in a 40-year-old alcoholic diabetic patient living in M\u00e9xico. Unfortunately, the late diagnosis resulted in his death despite the treatment and supportive measures. Increased awareness is needed to prevent the dire consequences of strongyloidiasis.<\/jats:p>","DOI":"10.7705\/biomedica.5071","type":"journal-article","created":{"date-parts":[[2020,5,27]],"date-time":"2020-05-27T21:32:34Z","timestamp":1590615154000},"page":"32-36","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":3,"title":["Fatal Strongyloides stercoralis hyperinfection syndrome in an alcoholic diabetic patient from M\u00e9xico"],"prefix":"10.7705","volume":"40","author":[{"given":"Elba G.","family":"Rodr\u00edguez-P\u00e9rez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alma Y.","family":"Arce-Mendoza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Sald\u00edvar-Palacios","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7173-7486","authenticated-orcid":false,"given":"Kevin","family":"Escand\u00f3n-Vargas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4444","published-online":{"date-parts":[[2020,5,1]]},"reference":[{"key":"97322","doi-asserted-by":"crossref","unstructured":"Olsen A, van Lieshout L, Marti H, Polderman T, Polman K, Steinmann P, et al. Strongyloidiasis \u2013 the most neglected of the neglected tropical diseases? Trans R Soc Trop Med Hyg. 2009;103:967-72. https:\/\/doi.org\/10.1016\/j.trstmh.2009.02.013","DOI":"10.1016\/j.trstmh.2009.02.013"},{"key":"97323","doi-asserted-by":"crossref","unstructured":"Bisoffi Z, Buonfrate D, Montresor A, Requena-M\u00e9ndez A, Mu\u00f1oz J, Krolewiecki AJ, et al. Strongyloides stercoralis: A plea for action. PLoS Negl Trop Dis. 2013;7:7-10. https:\/\/doi.org\/10.1371\/journal.pntd.0002214","DOI":"10.1371\/journal.pntd.0002214"},{"key":"97324","unstructured":"Guarner J, Matilde-Nava T, Villase\u00f1or-Flores R, S\u00e1nchez-Mejorada G. Frequency of intestinal parasites in adult cancer patients in M\u00e9xico. Arch Med Res. 1997;28:219-22."},{"key":"97325","doi-asserted-by":"crossref","unstructured":"Faulkner CT, Borrego-Garc\u00eda B, Logan MH, New JC, Patton S. Prevalence of endoparasitic infection in children and its relation with cholera prevention efforts in M\u00e9xico. Rev Panam Salud P\u00fablica. 2003;14:31-41. https:\/\/doi.org\/10.1590\/S1020-49892003000600006","DOI":"10.1590\/S1020-49892003000600006"},{"key":"97326","unstructured":"Carrada-Bravo T. Strongyloides stercoralis: ciclo vital, cuadros cl\u00ednicos, epidemiolog\u00eda, patolog\u00eda y terap\u00e9utica. Revista Latinoamericana de Patolog\u00eda Cl\u00ednica y Medicina de Laboratorio. 2008;55:88-110."},{"key":"97327","doi-asserted-by":"crossref","unstructured":"Viney ME, Lok JB. The biology of Strongyloides spp. Pasadena: WormBook; 2015. p. 1-17. https:\/\/doi.org\/10.1895\/wormbook.1.141.2","DOI":"10.1895\/wormbook.1.141.2"},{"key":"97328","doi-asserted-by":"crossref","unstructured":"Krolewiecki A, Nutman TB. Strongyloidiasis. Infect Dis Clin North Am. 2019;33:135-51. https:\/\/doi.org\/10.1016\/j.idc.2018.10.006","DOI":"10.1016\/j.idc.2018.10.006"},{"key":"97329","doi-asserted-by":"crossref","unstructured":"Teixeira MCA, Pacheco FTF, Souza JN, Silva MLS, In\u00eas EJ, Soares NM. Strongyloides stercoralis infection in alcoholic patients. Biomed Res Int. 2016;2016:4872473. https:\/\/doi.org\/10.1155\/2016\/4872473","DOI":"10.1155\/2016\/4872473"},{"key":"97330","doi-asserted-by":"crossref","unstructured":"McGuire E, Welch C, Melzer M. Is Strongyloides seropositivity associated with diabetes mellitus? A retrospective case-control study in an East London NHS Trust. Trans R Soc Trop Med Hyg. 2019;113:189-94. https:\/\/doi.org\/10.1093\/trstmh\/try132","DOI":"10.1093\/trstmh\/try132"},{"key":"97331","doi-asserted-by":"crossref","unstructured":"Silva MLS, de J. In\u00eas E, da S. Souza AB, dos S. Dias VM, Guimar\u00e3es CM, Menezes ER, et al. Association between Strongyloides stercoralis infection and cortisol secretion in alcoholic patients. Acta Trop. 2016;154:133-8. https:\/\/doi.org\/10.1016\/j.actatropica.2015.11.010","DOI":"10.1016\/j.actatropica.2015.11.010"},{"key":"97332","doi-asserted-by":"crossref","unstructured":"Buonfrate D, Requena-M\u00e9ndez A, Angheben A, Mu\u00f1oz J, Gobbi F, van Den Ende J, et al. Severe strongyloidiasis: A systematic review of case reports. BMC Infect Dis. 2013;13:78. https:\/\/doi.org\/10.1186\/1471-2334-13-78","DOI":"10.1186\/1471-2334-13-78"},{"key":"97333","doi-asserted-by":"crossref","unstructured":"Geri G, Rabbat A, Mayaux J, Zafrani L, Chalumeau-Lemoine L, Guidet B, et al. Strongyloides stercoralis hyperinfection syndrome: A case series and a review of the literature. Infection. 2015;43:691-8. https:\/\/doi.org\/10.1007\/s15010-015-0799-1","DOI":"10.1007\/s15010-015-0799-1"},{"key":"97334","doi-asserted-by":"crossref","unstructured":"Henr\u00edquez-Camacho C, Gotuzzo E, Echevarr\u00eda J, White AC, Terashima A, Samalvides F, et al. Ivermectin versus albendazole or thiabendazole for Strongyloides stercoralis infection. Cochrane Database Syst Rev. 2016;CD007745. https:\/\/doi.org\/10.1002\/14651858.CD007745.pub3","DOI":"10.1002\/14651858.CD007745.pub3"},{"key":"97335","doi-asserted-by":"crossref","unstructured":"Barrett J, Broderick C, Soulsby H, Wade P, Newsholme W. Subcutaneous ivermectin use in the treatment of severe Strongyloides stercoralis infection: Two case reports and a discussion of the literature. J Antimicrob Chemother. 2016;71:220-5. https:\/\/doi.org\/10.1093\/jac\/dkv315","DOI":"10.1093\/jac\/dkv315"}],"container-title":["Biom\u00e9dica"],"original-title":[],"link":[{"URL":"https:\/\/revistabiomedica.org\/index.php\/biomedica\/article\/download\/5071\/4456","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistabiomedica.org\/index.php\/biomedica\/article\/download\/5071\/4456","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,29]],"date-time":"2020-05-29T19:52:15Z","timestamp":1590781935000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistabiomedica.org\/index.php\/biomedica\/article\/view\/5071"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,1]]},"references-count":14,"journal-issue":{"issue":"Supl. 1","published-online":{"date-parts":[[2020,5,1]]}},"URL":"https:\/\/doi.org\/10.7705\/biomedica.5071","relation":{},"ISSN":["2590-7379","0120-4157"],"issn-type":[{"type":"electronic","value":"2590-7379"},{"type":"print","value":"0120-4157"}],"subject":[],"published":{"date-parts":[[2020,5,1]]},"assertion":[{"value":"2020-05-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}},{"value":"Yes","order":0,"name":"peer_reviewed","label":"Peer Reviewed","group":{"name":"peer_review","label":"Peer Review"}},{"value":"Instituto Nacional de Salud","name":"publisher","label":"This article is maintained by"},{"value":"Biomedica","name":"journaltitle","label":"Journal Title"},{"value":"Case presentation","name":"content_type","label":"Content Type"}]}}