{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T07:53:12Z","timestamp":1648626792158},"reference-count":32,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"3","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["biomedica"],"abstract":"<jats:p>Se presenta el caso de una mujer de 38 a\u00f1os que consult\u00f3 inicialmente por fiebre indiferenciada. A pesar de que el cuadro cl\u00ednico evolucion\u00f3 con manifestaciones cl\u00ednicas de dengue con signos de alarma y de que la detecci\u00f3n de IgM antidengue en una sola muestra indicaba que se trataba de un caso probable que hab\u00eda podido ocurrir durante los tres meses anteriores, la paciente consult\u00f3 de forma reiterada, pues no presentaba una mejor\u00eda significativa.En el d\u00e9cimo d\u00eda del inicio de los s\u00edntomas, se observ\u00f3 edema sim\u00e9trico en m\u00faltiples articulaciones acompa\u00f1ado de dolor, as\u00ed como lesiones hiperpigmentadas en el surco nasogeniano. Se confirm\u00f3 el diagn\u00f3stico de chikungunya por la presencia de anticuerpos IgM.Aunque puede pasar desapercibida, en los pa\u00edses end\u00e9micos para dengue y chikungunya existe la posibilidad de la infecci\u00f3n concomitante, la cual puede agravar la evoluci\u00f3n cl\u00ednica de cada una de estas enfermedades. Por ello, es necesario que el m\u00e9dico considere las caracter\u00edsticas cl\u00ednicas y de laboratorio de ambas enfermedades para diagnosticar su presencia simult\u00e1nea, garantizar un manejo adecuado y minimizar las complicaciones.<\/jats:p>","DOI":"10.7705\/biomedica.5085","type":"journal-article","created":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T19:26:44Z","timestamp":1601321204000},"page":"472-478","update-policy":"http:\/\/dx.doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":0,"title":["Importancia de las caracter\u00edsticas cl\u00ednicas y de laboratorio en el diagn\u00f3stico de las infecciones concomitantes por dengue y chikungunya: reporte de un caso probable"],"prefix":"10.7705","volume":"40","author":[{"given":"Berta Nelly","family":"Restrepo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margarita","family":"Arboleda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katerine","family":"Mar\u00edn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Romero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Luisa","family":"Mu\u00f1oz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene","family":"Bosch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4444","published-online":{"date-parts":[[2020,9,1]]},"reference":[{"key":"99744","unstructured":"Organizaci\u00f3n Mundial de la Salud. 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