{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T01:46:31Z","timestamp":1775094391985,"version":"3.50.1"},"reference-count":60,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"2","license":[{"start":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T00:00:00Z","timestamp":1624924800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["biomedica"],"abstract":"<jats:p>Introducci\u00f3n. El riesgo de infecci\u00f3n con Brucella canis en humanos y perros aumenta con la exposici\u00f3n constante a perros portadores asintom\u00e1ticos. En Colombia hay evidencia de infecci\u00f3n con B. canis en personas que conviven con perros. Una preocupaci\u00f3n adicional en Bogot\u00e1 es la falta de informaci\u00f3n actualizada sobre la prevalencia de la infecci\u00f3n en perros destinados a programas de adopci\u00f3n.Objetivo. Establecer la seroprevalencia de la infecci\u00f3n por B. canis en perros de un refugio para animales de compa\u00f1\u00eda destinados a la adopci\u00f3n en Bogot\u00e1.Materiales y m\u00e9todos. Se hizo un estudio descriptivo de corte transversal en un refugio ara animales de Bogot\u00e1. Se detectaron anticuerpos contra B. canis en el suero de 51 perros (28 hembras y 23 machos) mediante una prueba inmunocromatogr\u00e1fica de flujo lateral. Asimismo, los individuos positivos se analizaron con PCR para la detecci\u00f3n del ADN de Brucella spp.Resultado. La seroprevalencia de B. canis fue del 1,96 % (1\/51). El perro seropositivo correspondi\u00f3 a una hembra asintom\u00e1tica de tres a\u00f1os de edad en la cual no se detect\u00f3 ADN bacteriano en sangre mediante la PCR.Conclusiones. La seroprevalencia representada por un solo perro con IgG anti-B. canis puede considerarse un riesgo potencial para las poblaciones de perros y humanos, ya que podr\u00eda tratarse de un animal con infecci\u00f3n persistente capaz de diseminar la bacteria.<\/jats:p>","DOI":"10.7705\/biomedica.5409","type":"journal-article","created":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T13:20:29Z","timestamp":1625059229000},"page":"260-270","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":7,"title":["Seroprevalencia de Brucella canis en perros de un refugio para animales de compa\u00f1\u00eda en Bogot\u00e1, Colombia"],"prefix":"10.7705","volume":"41","author":[{"given":"Astrid-Jullieth","family":"Laverde","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Restrepo-Botero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Hern\u00e1ndez-Pulido","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Luis","family":"Rodr\u00edguez-Bautista","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel-Sof\u00eda","family":"Sandoval","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4444","published-online":{"date-parts":[[2021,6,29]]},"reference":[{"key":"104330","doi-asserted-by":"crossref","unstructured":"Batinga MC, Dos Santos JC, Lima JT, Bigotto MF, Muner K, Faita T, et al. Comparison of three methods for recovery of Brucella canis DNA from canine blood samples. J Microbiol Methods. 2017;143:26-31. https:\/\/doi.org\/10.1016\/j.mimet.2017.08.019","DOI":"10.1016\/j.mimet.2017.08.019"},{"key":"104331","doi-asserted-by":"crossref","unstructured":"Hensel ME, Negron M, Arenas-Gamboa AM. Brucellosis in dogs and public health risk. Emerg Infect Dis. 2018;24:1401-6. https:\/\/doi.org\/10.3201\/eid2408.171171","DOI":"10.3201\/eid2408.171171"},{"key":"104332","doi-asserted-by":"crossref","unstructured":"Pujol M, Borie C, Montoya M, Ferreira A, Vernal R. Brucella canis induces canine CD4+ T cells multi-cytokine Th1\/Th17 production via dendritic cell activation. Comp Immunol Microbiol Infect Dis. 2019;62:68-75. https:\/\/doi.org\/10.1016\/j.cimid.2018.11.017","DOI":"10.1016\/j.cimid.2018.11.017"},{"key":"104333","doi-asserted-by":"crossref","unstructured":"Olsen SC, Palmer MV. Advancement of knowledge of Brucella over the past 50 years. Vet Pathol. 2014;51:1076-89. https:\/\/doi.org\/10.1177\/0300985814540545","DOI":"10.1177\/0300985814540545"},{"key":"104334","doi-asserted-by":"crossref","unstructured":"Chac\u00f3n-D\u00edaz C, Altamirano-Silva P, Gonz\u00e1lez-Espinoza G, Medina MC, Alfaro-Alarc\u00f3n A, Bouza-Mora L, et al. Brucella canis is an intracellular pathogen that induces a lower proinflammatory response than smooth zoonotic counterparts. Infect Immun. 2015;83:4861-70. https:\/\/doi.org\/10.1128\/IAI.00995-15","DOI":"10.1128\/IAI.00995-15"},{"key":"104335","doi-asserted-by":"crossref","unstructured":"Gyuranecz M, Szeredi L, R\u00f3nai Z, D\u00e9nes B, Dencso L, D\u00e1n \u00c1, et al. Detection of Brucella canis-induced reproductive diseases in a Kennel. J Vet Diagnostic Investig. 2011;23:143-7. https:\/\/doi.org\/10.1177\/104063871102300127","DOI":"10.1177\/104063871102300127"},{"key":"104336","doi-asserted-by":"crossref","unstructured":"Byndloss MX, Tsolis RM. Brucella spp. virulence factors and immunity. Annu Rev Anim Biosci. 2016;4:111-27. https:\/\/doi.org\/10.1146\/annurev-animal-021815-111326","DOI":"10.1146\/annurev-animal-021815-111326"},{"key":"104337","unstructured":"Forbes JN, Frederick SW, Savage MY, Cross AR. Brucella canis sacroiliitis and discospondylitis in a dog. Can Vet J. 2019;60:1301-4."},{"key":"104338","doi-asserted-by":"crossref","unstructured":"Ledbetter EC, Landry MP, Stokol T, Kern TJ, Messick JB. Brucella canis endophthalmitis in 3 dogs: Clinical features, diagnosis, and treatment. Vet Ophthalmol. 2009;12:183-91. https:\/\/doi.org\/10.1111\/j.1463-5224.2009.00690.x","DOI":"10.1111\/j.1463-5224.2009.00690.x"},{"key":"104339","doi-asserted-by":"crossref","unstructured":"Keid LB, Chiebao DP, Batinga MC, Faita T, Diniz JA, Oliveira TM, et al. Brucella canis infection in dogs from commercial breeding kennels in Brazil. Transbound Emerg Dis. 2017;64:691-7. https:\/\/doi.org\/10.1111\/tbed.12632","DOI":"10.1111\/tbed.12632"},{"key":"104340","doi-asserted-by":"crossref","unstructured":"Johnson CA, Carter TD, Dunn JR, Baer SR, Schalow MM, Bellay YM, et al. Investigation and characterization of Brucella canis infections in pet-quality dogs and associated human exposures during a 2007\u20132016 outbreak in Michigan. J Am Vet Med Assoc. 2018;253:322-36. https:\/\/doi.org\/10.2460\/javma.253.3.322","DOI":"10.2460\/javma.253.3.322"},{"key":"104341","unstructured":"Carmichael LE, Joubert JC. Transmission of Brucella canis by contact exposure. Cornell Vet. 1988;78:63-73."},{"key":"104342","doi-asserted-by":"crossref","unstructured":"Kauffman LK, Petersen CA. Canine brucellosis: Old foe and reemerging scourge. Vet Clin North Am Small Anim Pract. 2019;49:763-79. https:\/\/doi.org\/10.1016\/j.cvsm.2019.02.013","DOI":"10.1016\/j.cvsm.2019.02.013"},{"key":"104343","doi-asserted-by":"crossref","unstructured":"De Souza TD, De Carvalho TF, Mol JP, Lopes JV, Silva MF, Da Paix\u00e3o TA, et al. Tissue distribution and cell tropism of Brucella canis in naturally infected canine foetuses and neonates. Sci Rep. 2018;8:7203-12. https:\/\/doi.org\/10.1038\/s41598-018-25651-x","DOI":"10.1038\/s41598-018-25651-x"},{"key":"104344","doi-asserted-by":"crossref","unstructured":"Wanke MM, Delpino MV, Baldi PC. Use of enrofloxacin in the treatment of canine brucellosis in a dog kennel (clinical trial). Theriogenology. 2006;66:1573-8. https:\/\/doi.org\/10.1016\/j.theriogenology","DOI":"10.1016\/j.theriogenology.2006.01.034"},{"key":"104345","doi-asserted-by":"crossref","unstructured":"Boeri EJ, Escobar GI, Ayala SM, Hasan D, Lucero NE. Tracking dogs infected with Brucella canis after antibiotic treatment. Arch Anim Husb Dairy Sci. 2018;1:1-4. https:\/\/doi.org\/10.33552\/AAHDS.2018.01.000505","DOI":"10.33552\/AAHDS.2018.01.000505"},{"key":"104346","doi-asserted-by":"crossref","unstructured":"Lucero NE, Corazza R, Almuzara MN, Reynes E, Escobar GI, Boeri E, et al. Human Brucella canis outbreak linked to infection in dogs. Epidemiol Infect. 2010;138:280-5. https:\/\/doi.org\/10.1017\/S0950268809990525","DOI":"10.1017\/S0950268809990525"},{"key":"104347","doi-asserted-by":"crossref","unstructured":"Krueger WS, Lucero NE, Brower A, Heil GL, Gray GC. Evidence for unapparent Brucella canis infections among adults with occupational exposure to dogs. Zoonoses Public Health. 2014;61:509-18. https:\/\/doi.org\/10.1111\/zph.12102","DOI":"10.1111\/zph.12102"},{"key":"104348","doi-asserted-by":"crossref","unstructured":"Castrill\u00f3n-Salazar L, Giraldo-Echeverri CA, S\u00e1nchez-Jim\u00e9nez MM, Olivera-Angel M. Factores asociados con la seropositividad a Brucella canis en criaderos caninos de dos regiones de Antioquia, Colombia. Cad Sa\u00fade P\u00fablica. 2013;29:1955-73. https:\/\/doi.org\/10.1590\/0102-311X00133013","DOI":"10.1590\/0102-311X00133013"},{"key":"104349","doi-asserted-by":"crossref","unstructured":"Makloski CL. Canine brucellosis management. Vet Clin North Am Small Anim Pract. 2011;41:1209-19. https:\/\/doi.org\/10.1016\/j.cvsm.2011.08.001","DOI":"10.1016\/j.cvsm.2011.08.001"},{"key":"104350","doi-asserted-by":"crossref","unstructured":"Olivera M, Di-Lorenzo C. Aislamiento de Brucella canis en un humano conviviente con caninos infectados. Informe de un caso. Colomb Med. 2009;40:218-20.","DOI":"10.25100\/cm.v40i2.645"},{"key":"104351","doi-asserted-by":"crossref","unstructured":"S\u00e1nchez-Jim\u00e9nez MM, Giraldo-Echeverri CA, Olivera-Angel M. Infecci\u00f3n por Brucella canis en humanos: propuesta de un modelo te\u00f3rico de infecci\u00f3n a trav\u00e9s de la ruta oral. Infectio. 2013;17:193-200. https:\/\/doi.org\/10.1016\/S0123-9392(13)70731-8","DOI":"10.1016\/S0123-9392(13)70731-8"},{"key":"104352","doi-asserted-by":"crossref","unstructured":"Giraldo-Echeverri CA, Ruiz-Cort\u00e9s ZT, Olivera-\u00c1ngel M. Brucella canis en Medell\u00edn (Colombia), un problema actual. Revista UDCA Actualidad & Divulgaci\u00f3n Cient\u00edfica. 2009;12:51-5.","DOI":"10.31910\/rudca.v12.n1.2009.641"},{"key":"104353","doi-asserted-by":"crossref","unstructured":"Whitten TV, Brayshaw G, Patnayak D, \u00c1lvarez J, Larson CM, Root Kustritz M, et al. Seroprevalence of Brucella canis antibodies in dogs entering a Minnesota humane society, Minnesota, 2016-2017. Prev Vet Med. 2019;168:90-4. https:\/\/doi.org\/10.1016\/j.prevetmed.2019.04.015","DOI":"10.1016\/j.prevetmed.2019.04.015"},{"key":"104354","doi-asserted-by":"crossref","unstructured":"Agudelo P, Molina V, Arias V, Madrigal E. Estudio serol\u00f3gico de brucelosis canina en dos albergues del municipio de Envigado, Colombia (2011). Revista de la Facultad de Medicina Veterinaria y de Zootecnia. 2014;61:134-41. https:\/\/doi.org\/10.15446\/rfmvz.v61n2.44676","DOI":"10.15446\/rfmvz.v61n2.44676"},{"key":"104355","unstructured":"Uribe R, Delgado K. Determinaci\u00f3n de la presencia de Brucella canis en caninos de dos refugios de la ciudad de Bucaramanga en 2012. CES Medicina Veterinaria y Zootecnia. 2013;8:95-103."},{"key":"104356","doi-asserted-by":"crossref","unstructured":"Ruiz-Buitrago JD, Giraldo-Echeverri CA, L\u00f3pez LV, Chica JF. Seroprevalencia de Brucella canis en perros callejeros del Centro de Bienestar Animal \u201cLa Perla\u201d, Medell\u00edn (Colombia), 2008. Revista Colombiana de Ciencias Pecuarias. 2010;23:166-72.","DOI":"10.17533\/udea.rccp.324559"},{"key":"104357","doi-asserted-by":"crossref","unstructured":"Tuemmers C, L\u00fcders C, Rojas C, Serri M, Castillo C, Espinoza R. Detecci\u00f3n de Brucella canis por m\u00e9todo de inmunocromatograf\u00eda en perros vagos capturados en la ciudad de Temuco, Chile, 2011. Rev Chil Infectol. 2013;30:395-401. https:\/\/doi.org\/10.4067\/S0716-10182013000400007","DOI":"10.4067\/S0716-10182013000400007"},{"key":"104358","doi-asserted-by":"crossref","unstructured":"Hubbard K, Wang M, Smith DR. Seroprevalence of brucellosis in Mississippi shelter dogs. Prev Vet Med. 2018;159:82-6. https:\/\/doi.org\/10.1016\/j.prevetmed.2018.09.002","DOI":"10.1016\/j.prevetmed.2018.09.002"},{"key":"104359","doi-asserted-by":"crossref","unstructured":"Chinyoka S, Dhliwayo S, Marabini L, Dutlow K, Matope G, Pfukenyi DM. Serological survey of Brucella canis in dogs in urban Harare and selected rural communities in Zimbabwe. J S Afr Vet Assoc. 2014;85:e1-e5. https:\/\/doi.org\/10.4102\/jsava.v85i1.1087","DOI":"10.4102\/jsava.v85i1.1087"},{"key":"104360","doi-asserted-by":"crossref","unstructured":"Hafemann DCM, Merlini LS, Gon\u00e7alves DD, Fortes MS, Navarro IT, Chiderolli RT, et al. Detection of anti-Leptospira spp., anti-Brucella spp., and anti-Toxoplasma gondii antibodies in stray dogs. J Venom Anim Toxins Incl Trop Dis. 2013;19:23-7. https:\/\/doi.org\/10.1186\/1678-9199-19-23","DOI":"10.1186\/1678-9199-19-23"},{"key":"104361","doi-asserted-by":"crossref","unstructured":"de Paula Dreer M, Gon\u00e7alves D, da Silva Caetano I, Ger\u00f4nimo E, Menegas P, Bergo D, et al. Toxoplasmosis, leptospirosis and brucellosis in stray dogs housed at the shelter in Umuarama municipality, Paran\u00e1, Brazil. J Venom Anim Toxins Incl Trop Dis. 2013;19:23-7. https:\/\/doi.org\/10.1186\/1678-9199-19-23","DOI":"10.1186\/1678-9199-19-23"},{"key":"104362","unstructured":"Anigen Rapid C. Brucella Ab Test Kit. Fecha de consulta: 28 de septiembre de 2020. Disponible en: http:\/\/www.vetpetspharma.com\/images\/productos\/canino\/CBrucellaAb\/CBrucellaAb.pdf"},{"key":"104363","doi-asserted-by":"crossref","unstructured":"Kim D, Park J, Kim SJ, Soh YM, Kim HM, Oh BH, et al. Brucella immunogenic BP26 forms a channel-like structure. J Mol Biol. 2013;425:1119-26. https:\/\/doi.org\/10.1016\/j.jmb.2013.01.015","DOI":"10.1016\/j.jmb.2013.01.015"},{"key":"104364","doi-asserted-by":"crossref","unstructured":"S\u00e1nchez-Jim\u00e9nez MM, Ortiz-Rom\u00e1n LF, Castrill\u00f3n-Salazar LL, Giraldo-Echeverri CA, Olivera-Angel M. Application of a polymerase chain reaction test for the detection of Brucella canis from clinical samples of canines and humans. Revista Colombiana de Ciencias Pecuarias. 2014;27:3-11.","DOI":"10.17533\/udea.rccp.324873"},{"key":"104365","doi-asserted-by":"crossref","unstructured":"Olivera M, Giraldo CA, Di Lorenzo C. PCR identification of Brucella canis in canine blood and milk. A case report. Arch Med Vet. 2011;43:295-8. https:\/\/doi.org\/10.4067\/S0301-732X2011000300012","DOI":"10.4067\/S0301-732X2011000300012"},{"key":"104366","unstructured":"C\u00e1rdenas D, Obando J, Moreno C, Mesa L, Ortiz A. Seroprevalencia de Brucella canis en la poblaci\u00f3n canina del centro de zoonosis de la ciudad de Villavicencio. Revista Electro\u0301nica de Veterinaria. 2017;18:1-11."},{"key":"104367","doi-asserted-by":"crossref","unstructured":"Pardo A, P\u00e9rez C, G\u00f3ngora A, G\u00f3mez L, Moreno A. Encuesta exploratoria de infecci\u00f3n por Brucella canis en perros de Villavicencio-Colombia. Rev MVZ C\u00f3rdoba. 2009;14:1690-6. https:\/\/doi.org\/10.21897\/rmvz.352","DOI":"10.21897\/rmvz.352"},{"key":"104368","unstructured":"Agudelo-Fl\u00f3rez P, Castro B, Rojo-Ospina R, Henao-Villegas S. Seroprevalencia y factores de riesgo para brucelosis canina en perros dom\u00e9sticos de once comunas de la ciudad de Medell\u00edn-Colombia. Rev Salud P\u00fablica (Bogot\u00e1). 2012;14:644-56."},{"key":"104369","doi-asserted-by":"crossref","unstructured":"Castrill\u00f3n-Salazar L, L\u00f3pez-Diez L, S\u00e1nchez-Nodarse R, Sanabria-Gonz\u00e1lez W, Henao-Correa E, Olivera-Angel M. Prevalencia de presentaci\u00f3n de algunos agentes zoon\u00f3ticos transmitidos por caninos y felinos en Medell\u00edn, Colombia. Rev MVZ C\u00f3rdoba. 2019;24:7119-26. https:\/\/doi.org\/10.21897\/rmvz.1524","DOI":"10.21897\/rmvz.1524"},{"key":"104370","unstructured":"Ballut JC, Calder\u00f3n A, Rodr\u00edguez V. Brucelosis en hembras caninas en Monter\u00eda (Colombia): un problema para la salud p\u00fablica. Biosalud. 2013;12:66-74."},{"key":"104371","doi-asserted-by":"crossref","unstructured":"Kaltungo BY, Saidu SNA, Sackey AKB, Kazeem HM. A review on diagnostic techniques for brucellosis. Afr J Biotechnol. 2014;13:1-10. https:\/\/doi.org\/10.5897\/AJB2013.13442","DOI":"10.5897\/AJB2013.13442"},{"key":"104372","doi-asserted-by":"crossref","unstructured":"Carmichael LE, Shin SJ. Canine brucellosis: A diagnostician\u2019s dilemma. Semin Vet Med Surg Small Anim. 1996;11:161-5. https:\/\/doi.org\/10.1016\/s1096-2867(96)80028-4","DOI":"10.1016\/S1096-2867(96)80028-4"},{"key":"104373","doi-asserted-by":"crossref","unstructured":"Hollett RB. Canine brucellosis: Outbreaks and compliance. Theriogenology. 2006;66:575-87. https:\/\/doi.org\/10.1016\/j.theriogenology.2006.04.011","DOI":"10.1016\/j.theriogenology.2006.04.011"},{"key":"104374","unstructured":"Greene CE, Carmichael LE. Canine brucellosis. En: Sykes J, Greene J, editors. Infectious Diseases of the Dog and Cat. 4th edition. London: Elsevier Health Sciences; 2012. p. 398-411."},{"key":"104375","unstructured":"Cosford KL. Brucella canis: An update on research and clinical management. Can Vet J. 2018;59:74-81."},{"key":"104376","doi-asserted-by":"crossref","unstructured":"Ardoino SM, Baruta DA, Toso RE. Brucelosis canina. Ciencia Veterinaria. 2006;8:49-60. 48. Wanke M. Canine brucellosis. Anim Reprod Sci. 2004;82-83:195-207. https:\/\/doi.org\/10.1016\/j.anireprosci.2004.05.005","DOI":"10.1016\/j.anireprosci.2004.05.005"},{"key":"104377","doi-asserted-by":"crossref","unstructured":"De Souza TD, De Carvalho TF, Mol JPDS, Lopes JVM, Silva MF, Da Paix\u00e3o TA, et al. Tissue distribution and cell tropism of Brucella canis in naturally infected canine foetuses and neonates. Sci Rep. 2018;8:7203-12. https:\/\/doi.org\/10.1038\/s41598-018-25651-x","DOI":"10.1038\/s41598-018-25651-x"},{"key":"104378","doi-asserted-by":"crossref","unstructured":"Aras Z, U\u00e7an US. Detection of Brucella canis from inguinal lymph nodes of naturally infected dogs by PCR. Theriogenology. 2010;74:658-62. https:\/\/doi.org\/10.1016\/j.theriogenology.2010.03.023","DOI":"10.1016\/j.theriogenology.2010.03.023"},{"key":"104379","doi-asserted-by":"crossref","unstructured":"Daly R, Willis KC, Wood J, Brown K, Brown D, Beguin-Strong T, et al. Seroprevalence of Brucella canis in dogs rescued from South Dakota Indian reservations, 2015-2019. Prev Vet Med. 2020;184:105157. https:\/\/doi.org\/10.1016\/j.prevetmed.2020.105157","DOI":"10.1016\/j.prevetmed.2020.105157"},{"key":"104380","doi-asserted-by":"crossref","unstructured":"Oosthuizen J, Oguttu JW, Etsebeth C, Gouws WF, Fasina FO. Risk factors associated with the occurrence of Brucella canis seropositivity in dogs within selected provinces of South Africa. J S Afr Vet Assoc. 2019;90:e1-e8. https:\/\/doi.org\/10.4102\/jsava.v90i0.1956","DOI":"10.4102\/jsava.v90i0.1956"},{"key":"104381","doi-asserted-by":"crossref","unstructured":"Lawaczeck E, Toporek J, Cwikla J, Mathison BA. Brucella canis in a HIV-infected patient. Zoonoses Public Health. 2011;58:150-2. https:\/\/doi.org\/10.1111\/j.1863-2378.2010.01334.x","DOI":"10.1111\/j.1863-2378.2010.01334.x"},{"key":"104382","doi-asserted-by":"crossref","unstructured":"Lucero NE, Maldonado PI, Kaufman S, Escobar GI, Boeri E, Jacob NR. Brucella canis causing infection in an HIV-infected patient. Vector Borne Zoonotic Dis. 2010;10:527-9. https:\/\/doi.org\/10.1089\/vbz.2009.0034","DOI":"10.1089\/vbz.2009.0034"},{"key":"104383","doi-asserted-by":"crossref","unstructured":"Dentinger CM, Jacob K, Lee LV, M\u00e9ndez HA, Chotikanatis K, Mcdonough PL, et al. Human Brucella canis infection and subsequent laboratory exposures associated with a puppy, New York City, 2012. Zoonoses Public Health. 2015;62:407-14. https:\/\/doi.org\/10.1111\/zph.12163","DOI":"10.1111\/zph.12163"},{"key":"104384","doi-asserted-by":"crossref","unstructured":"Lucero NE, Escobar GI, Ayala SM, Jacob N. Diagnosis of human brucellosis caused by Brucella canis. J Med Microbiol. 2005;54:457-61. https:\/\/doi.org\/10.1099\/jmm.0.45927-0","DOI":"10.1099\/jmm.0.45927-0"},{"key":"104385","doi-asserted-by":"crossref","unstructured":"Tosi MF, Nelson TJ. Brucella canis infection in a 17-month-old child successfully treated with moxalactam. J Pediatr. 1982;101:725-7. https:\/\/doi.org\/10.1016\/s0022-3476(82)80301-6","DOI":"10.1016\/S0022-3476(82)80301-6"},{"key":"104386","doi-asserted-by":"crossref","unstructured":"Nomura A, Imaoka K, Imanishi H, Shimizu H, Nagura F, Maeda K, et al. Human Brucella canis infections diagnosed by blood culture. Emerg Infect Dis. 2010;16:1183-5. https:\/\/doi.org\/10.3201\/eid1607.090209","DOI":"10.3201\/eid1607.090209"},{"key":"104387","doi-asserted-by":"crossref","unstructured":"Swenson RM, Carmichael LE, Cundy KR. Human infection with Brucella canis. Ann Intern Med. 1972;76:435-8. https:\/\/doi.org\/10.7326\/0003-4819-76-3-435","DOI":"10.7326\/0003-4819-76-3-435"},{"key":"104388","doi-asserted-by":"crossref","unstructured":"Smith LM, Hartmann S, Munteanu AM, Villa PD, Quinnell RJ, Collins LM. The effectiveness of dog population management: A systematic review. Animals (Basel). 2019;9:1020-49. https:\/\/doi.org\/10.3390\/ani9121020","DOI":"10.3390\/ani9121020"},{"key":"104389","doi-asserted-by":"crossref","unstructured":"Maia C, Almeida B, Coimbra M, Fernandes MC, Crist\u00f3v\u00e3o JM, Ramos C, et al. Bacterial and protozoal agents of canine vector-borne diseases in the blood of domestic and stray dogs from southern Portugal. Parasit Vectors. 2015;8:138-44. https:\/\/doi.org\/10.1186\/s13071-015-0759-8","DOI":"10.1186\/s13071-015-0759-8"}],"container-title":["Biom\u00e9dica"],"original-title":[],"link":[{"URL":"https:\/\/revistabiomedica.org\/index.php\/biomedica\/article\/download\/5409\/4746","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistabiomedica.org\/index.php\/biomedica\/article\/download\/5409\/4746","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T00:33:04Z","timestamp":1725323584000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistabiomedica.org\/index.php\/biomedica\/article\/view\/5409"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,29]]},"references-count":60,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,6,29]]}},"URL":"https:\/\/doi.org\/10.7705\/biomedica.5409","relation":{},"ISSN":["2590-7379","0120-4157"],"issn-type":[{"value":"2590-7379","type":"electronic"},{"value":"0120-4157","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6,29]]},"assertion":[{"value":"2021-05-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}},{"value":"Yes","order":0,"name":"peer_reviewed","label":"Peer Reviewed","group":{"name":"peer_review","label":"Peer Review"}},{"value":"Instituto Nacional de Salud","name":"publisher","label":"This article is maintained by"},{"value":"Biomedica","name":"journaltitle","label":"Journal Title"},{"value":"Original article","name":"content_type","label":"Content Type"}]}}