{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T01:24:31Z","timestamp":1778808271073,"version":"3.51.4"},"reference-count":21,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"2","license":[{"start":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T00:00:00Z","timestamp":1624924800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["biomedica"],"abstract":"<jats:p>El s\u00edndrome verrugoso tropical comprende condiciones cut\u00e1neas infecciosas, cr\u00f3nicas y granulomatosas que cursan con placas, n\u00f3dulos o \u00falceras verrugosas, de ah\u00ed su nombre. Este s\u00edndrome incluye la cromoblastomicosis, la esporotricosis, la paracoccidioidomicosis, la lobomicosis, la leishmaniasis y la tuberculosis cut\u00e1nea verrugosa, todas ellas enfermedades de amplia distribuci\u00f3n en \u00e1reas tropicales y subtropicales. Sus diagn\u00f3sticos pueden ser dif\u00edciles y confundirse entre s\u00ed, lo cual es m\u00e1s frecuente entre la esporotricosis y la leishmaniasis. Para distinguirlas se recurre a criterios cl\u00ednicos y epidemiol\u00f3gicos, y a m\u00e9todos diagn\u00f3sticos como intradermorreacci\u00f3n, examen directo, biopsia, cultivo, inmunofluorescencia y PCR, algunos de los cuales no son de uso com\u00fan. El diagn\u00f3stico preciso conduce al tratamiento adecuado. Se presenta el caso de un hombre de 18 a\u00f1os con extensas placas verrugosas en una rodilla, inicialmente interpretadas como leishmaniasis verrugosa por la cl\u00ednica, la epidemiolog\u00eda y la biopsia. Se le trat\u00f3 con Glucantime\u00ae durante 20 d\u00edas, pero no present\u00f3 mejor\u00eda, por lo que se tom\u00f3 una nueva biopsia que tambi\u00e9n se interpret\u00f3 como leishmaniasis cut\u00e1nea. La revisi\u00f3n de ambas biopsias evidenci\u00f3 inflamaci\u00f3n con granulomas abscedados y presencia de cuerpos asteroides esporotric\u00f3sicos, que condujeron al diagn\u00f3stico de esporotricosis, el cual se confirm\u00f3 luego con el cultivo del hongo. Las lesiones remitieron con la administraci\u00f3n de itraconazol.La cl\u00ednica y la epidemiolog\u00eda de la leishmaniasis y las de la esporotricosis pueden ser semejantes, por lo que la biopsia y los estudios de laboratorio son esenciales para establecer el diagn\u00f3stico. El cuerpo asteroide esporotric\u00f3sico es patognom\u00f3nico de esta entidad.<\/jats:p>","DOI":"10.7705\/biomedica.5757","type":"journal-article","created":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T13:20:29Z","timestamp":1625059229000},"page":"240-246","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":3,"title":["Hombre de 18 a\u00f1os con s\u00edndrome verrugoso tropical: \u00bfleishmaniasis o esporotricosis?"],"prefix":"10.7705","volume":"41","author":[{"given":"Paola","family":"Mac\u00edas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliana","family":"Ord\u00f3\u00f1ez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia M.","family":"Arenas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerza\u00edn","family":"Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4444","published-online":{"date-parts":[[2021,6,29]]},"reference":[{"key":"104089","unstructured":"Rodr\u00edguez G, Arenas C, Ovalle C, Hern\u00e1ndez CA, Camargo C. 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