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Aunque la muerte por CHIKV es poco frecuente, la enfermedad puede llegar a ser incapacitante y generar un amplio espectro de manifestaciones at\u00edpicas, como complicaciones cardiovasculares, respiratorias, oculares, renales y d\u00e9rmicas, entre otras. Cuando el dolor articular persiste por tres o m\u00e1s meses, da lugar a la forma cr\u00f3nica de la enfermedad denominada reumatismo inflamatorio cr\u00f3nico poschikungu\u00f1a, el cual es la principal secuela de la enfermedad. Se considera que este virus no es neurotr\u00f3pico, sin embargo, puede afectar el sistema nervioso central y generar secuelas graves y permanentes, principalmente, en ni\u00f1os y ancianos.En \u00c1frica, Asia y Europa se hab\u00edan reportado anteriormente brotes epid\u00e9micos por CHIKV, pero solo hasta finales del 2013 se document\u00f3 la introducci\u00f3n del virus a las Am\u00e9ricas; desde entonces, el virus se ha propagado a 45 pa\u00edses o territorios del continente y el n\u00famero de casos acumulados ascendi\u00f3 a cerca de dos millones en dos a\u00f1os.Esta revisi\u00f3n describe de manera general la biolog\u00eda molecular del virus, sus manifestaciones cl\u00ednicas, su patog\u00e9nesis y las principales complicaciones posteriores a la infecci\u00f3n. Adem\u00e1s, re\u00fane la informaci\u00f3n de la epidemia en Colombia y el continente americano publicada entre el 2014 y el 2020.<\/jats:p>","DOI":"10.7705\/biomedica.5797","type":"journal-article","created":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T09:20:29Z","timestamp":1625044829000},"page":"353-373","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":10,"title":["Reconociendo el virus del chikungu\u00f1a"],"prefix":"10.7705","volume":"41","author":[{"given":"Eliana Patricia","family":"Calvo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8633-8031","authenticated-orcid":false,"given":"Edwin Dar\u00edo","family":"Archila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3595-1602","authenticated-orcid":false,"given":"Lady","family":"L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1596-8383","authenticated-orcid":false,"given":"Jaime Eduardo","family":"Castellanos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4444","published-online":{"date-parts":[[2021,6,29]]},"reference":[{"key":"104857","doi-asserted-by":"crossref","unstructured":"Her Z, Kam Y, Lin R, Ng L. 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